SG149045A1 - Novel fused pyrrolocarbazoles - Google Patents

Novel fused pyrrolocarbazoles

Info

Publication number: SG149045A1
Authority: SG; Singapore
Prior art keywords: fused pyrrolocarbazoles; novel fused; pyrrolocarbazoles; present; novel
Prior art date: 2003-12-23

Application number

SG200809413-8A

Other languages

English (en)

Inventor

Nadine C Becknell

James L Diebold

Diane E Gingrich

Robert L Hudkins

Dandu R Reddy

Ming Tao

Theodore L Underiner

Allison L Zulli

Original Assignee

Cephalon Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-23

Filing date

2004-12-23

Publication date

2009-01-29

2004-12-23 Application filed by Cephalon Inc filed Critical Cephalon Inc

2009-01-29 Publication of SG149045A1 publication Critical patent/SG149045A1/en

Links

QNMMYUBZGLXCCK-UHFFFAOYSA-N pyrrolo[3,2-a]carbazole Chemical class N1=C2C=CC=CC2=C2C1=C1C=CN=C1C=C2 QNMMYUBZGLXCCK-UHFFFAOYSA-N 0.000 title abstract 3
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Psychology (AREA)
Virology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
AIDS & HIV (AREA)
Communicable Diseases (AREA)

SG200809413-8A 2003-12-23 2004-12-23 Novel fused pyrrolocarbazoles SG149045A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US53218203P	2003-12-23	2003-12-23
US11/017,947 US7169802B2 (en)	2003-12-23	2004-12-22	Fused pyrrolocarbazoles

Publications (1)

Publication Number	Publication Date
SG149045A1 true SG149045A1 (en)	2009-01-29

Family

ID=34703676

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG200809413-8A SG149045A1 (en)	2003-12-23	2004-12-23	Novel fused pyrrolocarbazoles

Country Status (29)

Country	Link
US (4)	US7169802B2 (de)
EP (1)	EP1704148B1 (de)
JP (1)	JP5006046B2 (de)
KR (2)	KR101179372B1 (de)
CN (1)	CN1918162B (de)
AR (1)	AR047168A1 (de)
AT (1)	ATE500256T1 (de)
AU (1)	AU2004309394B2 (de)
BR (1)	BRPI0418113B8 (de)
CA (1)	CA2549627C (de)
CR (1)	CR8519A (de)
CY (1)	CY1111524T1 (de)
DE (1)	DE602004031672D1 (de)
DK (1)	DK1704148T3 (de)
EA (1)	EA012295B1 (de)
HR (1)	HRP20110373T1 (de)
IL (1)	IL176384A (de)
IS (1)	IS8519A (de)
MA (1)	MA28298A1 (de)
MY (2)	MY143373A (de)
NO (2)	NO336893B1 (de)
NZ (1)	NZ548099A (de)
PL (1)	PL1704148T3 (de)
PT (1)	PT1704148E (de)
RS (1)	RS51886B (de)
SG (1)	SG149045A1 (de)
SI (1)	SI1704148T1 (de)
TW (1)	TWI355385B (de)
WO (1)	WO2005063763A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060276497A1 (en) *	2000-05-09	2006-12-07	Cephalon, Inc.	Novel multicyclic compounds and the use thereof
US7241779B2 (en) *	2003-12-23	2007-07-10	Cephalon, Inc.	Fused pyrrolocarbazoles
SE0401790D0 (sv) *	2004-07-07	2004-07-07	Forskarpatent I Syd Ab	Tamoxifen response in pre- and postmenopausal breast cancer patients
EP2064178A4 (de) *	2006-09-08	2011-10-05	Merck Canada Inc	Prodrugs von inhibitoren von cathepsin s
US20080125377A1 (en) *	2006-11-28	2008-05-29	Bartels Stephen P	Delivery system for antiangiogenic and antiinflammatory pharmaceuticals and method of use
US9061009B2 (en) *	2007-06-08	2015-06-23	University Of Massachusetts	Mixed lineage kinases and metabolic disorders
TWI580694B (zh)	2007-11-30	2017-05-01	建南德克公司	抗-ｖｅｇｆ抗體
UA107652C2 (en)	2008-10-06	2015-02-10	Incuron Llc	Carbazole compounds and therapeutic uses of the compounds
BRPI0919564A2 (pt)	2008-10-22	2019-09-24	Genentech, Inc	modulação da degeneração do axônio
WO2010059795A1 (en) *	2008-11-19	2010-05-27	Cephalon, Inc.	Novel forms of an indazolo [5,4-a] pyrrolo [3,4-c] carbazole compound
EP2192121A1 (de) *	2008-11-27	2010-06-02	Cephalon France	Regioselektive Reduktion von fusionierten Pyrrolocarbazol-5,7-Dionen
ES2554623T3 (es) *	2008-12-30	2015-12-22	Arqule, Inc.	Compuestos de 5,6-dihidro-6-fenilbenzo[f]isoquinolin-2-amina sustituida
US8263610B2 (en) *	2008-12-30	2012-09-11	Arqule, Inc.	Substituted imidazolyl-5,6-dihydrobenzo[N]isoquinoline compounds
CN104043126A (zh) *	2009-10-22	2014-09-17	霍夫曼-拉罗奇有限公司	轴突变性的调节
US20110189174A1 (en) *	2010-02-01	2011-08-04	Afshin Shafiee	Compositions and methods for treating, reducing, ameliorating, alleviating, or inhibiting progression of, pathogenic ocular neovascularization
EP2571885B1 (de) *	2010-05-18	2014-11-12	Cephalon, Inc.	Verfahren zur reinigung eines fusionierten pyrrolocarbazolderivates
CN103664797A (zh) *	2012-09-25	2014-03-26	杨子娇	一类治疗房角狭窄的化合物及其用途
CN104370880A (zh) *	2013-01-24	2015-02-25	韩冰	一类蛋白酶抑制剂及其制备方法和用途
EP2954331B1 (de)	2013-02-11	2018-03-28	Incuron LLC	Verwendung von facilitates chromatintranskriptionskomplex (fact) bei krebs
EP3049077A4 (de) *	2013-09-26	2017-02-15	CHDI Foundation, Inc.	Kynurenin-3-monooxygenase-hemmer, pharmazeutische zusammensetzungen und verfahren zur verwendung davon
CN106572992A (zh)	2014-04-06	2017-04-19	英丘伦有限责任公司	用curaxins进行组合治疗

Family Cites Families (15)

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NZ245203A (en)	1991-11-29	1997-07-27	Banyu Pharma Co Ltd	5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates
US5594009A (en)	1994-10-14	1997-01-14	Cephalon, Inc.	Fused pyrrolocarbazoles
US5475110A (en)	1994-10-14	1995-12-12	Cephalon, Inc.	Fused Pyrrolocarbazoles
US5705511A (en) *	1994-10-14	1998-01-06	Cephalon, Inc.	Fused pyrrolocarbazoles
US5591855A (en)	1994-10-14	1997-01-07	Cephalon, Inc.	Fused pyrrolocarbazoles
US5616724A (en)	1996-02-21	1997-04-01	Cephalon, Inc.	Fused pyrrolo[2,3-c]carbazole-6-ones
JP2000516250A (ja)	1996-08-22	2000-12-05	ブリストルーマイヤーズスクイブカンパニー	インドロピロロカルバゾールの細胞毒性アミノ糖および関連する糖誘導体
US6841567B1 (en)	1999-02-12	2005-01-11	Cephalon, Inc.	Cyclic substituted fused pyrrolocarbazoles and isoindolones
US6399780B1 (en)	1999-08-20	2002-06-04	Cephalon, Inc.	Isomeric fused pyrrolocarbazoles and isoindolones
US6630500B2 (en)	2000-08-25	2003-10-07	Cephalon, Inc.	Selected fused pyrrolocarbazoles
DK1325011T3 (da) *	2000-09-29	2004-08-16	Lilly Co Eli	Fremgangsmåder og forbindelser til behandling af proliferative sygdomme
US6653290B2 (en)	2000-10-06	2003-11-25	Bristol-Myers Squibb Company	Tumor proliferation inhibitors
US6610727B2 (en)	2000-10-06	2003-08-26	Bristol-Myers Squibb Company	Anhydro sugar derivatives of indolocarbazoles
AR035971A1 (es)	2001-05-16	2004-07-28	Cephalon Inc	Metodos para el tratamiento y la prevencion del dolor
US7241779B2 (en) *	2003-12-23	2007-07-10	Cephalon, Inc.	Fused pyrrolocarbazoles

2004
- 2004-12-22 US US11/017,947 patent/US7169802B2/en not_active Expired - Lifetime
- 2004-12-23 SI SI200431670T patent/SI1704148T1/sl unknown
- 2004-12-23 MY MYPI20045332A patent/MY143373A/en unknown
- 2004-12-23 DE DE602004031672T patent/DE602004031672D1/de not_active Expired - Lifetime
- 2004-12-23 PT PT04815262T patent/PT1704148E/pt unknown
- 2004-12-23 KR KR1020067014792A patent/KR101179372B1/ko not_active Expired - Fee Related
- 2004-12-23 PL PL04815262T patent/PL1704148T3/pl unknown
- 2004-12-23 CA CA2549627A patent/CA2549627C/en not_active Expired - Lifetime
- 2004-12-23 AT AT04815262T patent/ATE500256T1/de active
- 2004-12-23 AU AU2004309394A patent/AU2004309394B2/en not_active Expired
- 2004-12-23 NZ NZ548099A patent/NZ548099A/en not_active IP Right Cessation
- 2004-12-23 HR HR20110373T patent/HRP20110373T1/hr unknown
- 2004-12-23 TW TW093140222A patent/TWI355385B/zh not_active IP Right Cessation
- 2004-12-23 BR BRPI0418113A patent/BRPI0418113B8/pt active IP Right Grant
- 2004-12-23 JP JP2006547322A patent/JP5006046B2/ja not_active Expired - Lifetime
- 2004-12-23 EP EP04815262A patent/EP1704148B1/de not_active Expired - Lifetime
- 2004-12-23 MY MYPI20093362A patent/MY158159A/en unknown
- 2004-12-23 WO PCT/US2004/043160 patent/WO2005063763A1/en not_active Ceased
- 2004-12-23 EA EA200601217A patent/EA012295B1/ru not_active IP Right Cessation
- 2004-12-23 KR KR1020127011232A patent/KR20120066057A/ko not_active Ceased
- 2004-12-23 DK DK04815262.3T patent/DK1704148T3/da active
- 2004-12-23 CN CN200480041770.5A patent/CN1918162B/zh not_active Expired - Lifetime
- 2004-12-23 SG SG200809413-8A patent/SG149045A1/en unknown
- 2004-12-23 RS RS20110203A patent/RS51886B/sr unknown
- 2004-12-27 AR ARP040104890A patent/AR047168A1/es not_active Application Discontinuation
2006
- 2006-06-18 IL IL176384A patent/IL176384A/en active IP Right Grant
- 2006-06-22 IS IS8519A patent/IS8519A/xx unknown
- 2006-06-29 US US11/477,639 patent/US7671064B2/en not_active Expired - Lifetime
- 2006-07-10 NO NO20063196A patent/NO336893B1/no not_active IP Right Cessation
- 2006-07-17 MA MA29192A patent/MA28298A1/fr unknown
- 2006-07-19 CR CR8519A patent/CR8519A/es unknown
2010
- 2010-02-18 US US12/708,306 patent/US8044064B2/en not_active Expired - Lifetime
2011
- 2011-06-01 CY CY20111100533T patent/CY1111524T1/el unknown
- 2011-09-16 US US13/234,501 patent/US8383813B2/en not_active Expired - Lifetime
2015
- 2015-09-23 NO NO20151245A patent/NO20151245A1/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
US7169802B2 (en)	2007-01-30
PT1704148E (pt)	2011-05-25
WO2005063763A1 (en)	2005-07-14
PL1704148T3 (pl)	2011-07-29
EP1704148B1 (de)	2011-03-02
US20120004253A1 (en)	2012-01-05
CN1918162B (zh)	2014-05-14
EA200601217A1 (ru)	2006-12-29
HK1096096A1 (en)	2007-05-25
JP2007516293A (ja)	2007-06-21
CR8519A (es)	2007-06-06
NO20151245A1 (no)	2015-09-23
EP1704148A1 (de)	2006-09-27
EA012295B1 (ru)	2009-08-28
TW200530243A (en)	2005-09-16
AU2004309394B2 (en)	2011-04-28
DK1704148T3 (da)	2011-06-14
KR101179372B1 (ko)	2012-09-03
TWI355385B (en)	2012-01-01
NO336893B1 (no)	2015-11-23
US20050143442A1 (en)	2005-06-30
BRPI0418113B8 (pt)	2021-05-25
NO20063196L (no)	2006-09-20
DE602004031672D1 (de)	2011-04-14
KR20120066057A (ko)	2012-06-21
ATE500256T1 (de)	2011-03-15
AU2004309394A1 (en)	2005-07-14
US20060247294A1 (en)	2006-11-02
IL176384A0 (en)	2006-10-05
BRPI0418113A (pt)	2007-04-17
IL176384A (en)	2015-05-31
US7671064B2 (en)	2010-03-02
AR047168A1 (es)	2006-01-11
MY158159A (en)	2016-09-15
RS51886B (sr)	2012-02-29
CY1111524T1 (el)	2015-08-05
MY143373A (en)	2011-04-29
JP5006046B2 (ja)	2012-08-22
HRP20110373T1 (hr)	2011-06-30
NZ548099A (en)	2010-05-28
US20100152196A1 (en)	2010-06-17
CN1918162A (zh)	2007-02-21
SI1704148T1 (sl)	2011-06-30
KR20060127069A (ko)	2006-12-11
US8383813B2 (en)	2013-02-26
BRPI0418113B1 (pt)	2020-04-14
CA2549627A1 (en)	2005-07-14
MA28298A1 (fr)	2006-11-01
IS8519A (is)	2006-06-22
US8044064B2 (en)	2011-10-25
CA2549627C (en)	2012-12-11

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MXPA04005151A (es)	2004-08-11	Compuestos terapeuticos.