SG42355A1 - Stable liquid composition containing urate oxidase and lyophilized composition for its preparation - Google Patents
Stable liquid composition containing urate oxidase and lyophilized composition for its preparationInfo
- Publication number
- SG42355A1 SG42355A1 SG1996006306A SG1996006306A SG42355A1 SG 42355 A1 SG42355 A1 SG 42355A1 SG 1996006306 A SG1996006306 A SG 1996006306A SG 1996006306 A SG1996006306 A SG 1996006306A SG 42355 A1 SG42355 A1 SG 42355A1
- Authority
- SG
- Singapore
- Prior art keywords
- urate oxidase
- preparation
- stable liquid
- composition containing
- liquid composition
- Prior art date
Links
- 108010092464 Urate Oxidase Proteins 0.000 title abstract 3
- 229940005267 urate oxidase Drugs 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 title 1
- CTKXFMQHOOWWEB-UHFFFAOYSA-N Ethylene oxide/propylene oxide copolymer Chemical compound CCCOC(C)COCCO CTKXFMQHOOWWEB-UHFFFAOYSA-N 0.000 abstract 2
- 229920001993 poloxamer 188 Polymers 0.000 abstract 2
- 229940044519 poloxamer 188 Drugs 0.000 abstract 2
- -1 polyoxyethylene Polymers 0.000 abstract 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 229920001451 polypropylene glycol Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9505606A FR2733914B1 (fr) | 1995-05-11 | 1995-05-11 | Composition de liquide stable contenant de l'urate oxydase et composition lyophilisee pour sa preparation |
| US08/644,163 US5811096A (en) | 1995-05-11 | 1996-05-10 | Stable liquid composition containing urate oxidase and lyophilized composition for its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG42355A1 true SG42355A1 (en) | 1997-08-15 |
Family
ID=26231954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG1996006306A SG42355A1 (en) | 1995-05-11 | 1996-05-10 | Stable liquid composition containing urate oxidase and lyophilized composition for its preparation |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5811096A (da) |
| EP (1) | EP0742013B1 (da) |
| JP (1) | JP2950775B2 (da) |
| CN (1) | CN1090972C (da) |
| AT (1) | ATE183925T1 (da) |
| AU (1) | AU710288B2 (da) |
| BR (1) | BR1100337A (da) |
| CA (1) | CA2175971C (da) |
| CZ (1) | CZ290799B6 (da) |
| DE (1) | DE69604009T2 (da) |
| DK (1) | DK0742013T3 (da) |
| EA (1) | EA000024B1 (da) |
| ES (1) | ES2137635T3 (da) |
| FR (1) | FR2733914B1 (da) |
| GR (1) | GR3031896T3 (da) |
| HU (1) | HU225147B1 (da) |
| IL (1) | IL118171A (da) |
| NO (1) | NO315261B1 (da) |
| NZ (1) | NZ286554A (da) |
| PL (1) | PL184135B1 (da) |
| SG (1) | SG42355A1 (da) |
| SI (1) | SI0742013T1 (da) |
| TW (1) | TW420614B (da) |
| ZA (1) | ZA963683B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030166525A1 (en) * | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
| EP2158923B1 (en) * | 1998-08-06 | 2013-02-27 | Mountain View Pharmaceuticals, Inc. | Peg-urate oxidase conjugates and use thereof |
| US6783965B1 (en) | 2000-02-10 | 2004-08-31 | Mountain View Pharmaceuticals, Inc. | Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates |
| FR2782455B3 (fr) * | 1998-08-20 | 2000-09-15 | Sanofi Sa | Composition pharmaceutique injectable a base d'un sel pharmaceutiquement acceptable du clopidogrel ou de ticlopidine |
| CA2517310C (en) * | 2003-02-28 | 2015-11-24 | Chugai Seiyaku Kabushiki Kaisha | Stabilized protein-containing formulations comprising a poloxamer |
| AU2004226666B9 (en) * | 2003-04-02 | 2010-04-08 | Ares Trading S.A. | Liquid pharmaceutical formulations of FSH and LH together with a non-ionic surfactant |
| AU2004248931B2 (en) * | 2003-06-20 | 2009-07-16 | Ares Trading S.A. | Freeze-dried FSH / LH formulations |
| DK3321359T3 (da) | 2005-04-11 | 2021-03-08 | Horizon Pharma Rheumatology Llc | Variante former af uratoxidase og anvendelse deraf |
| US8148123B2 (en) * | 2005-04-11 | 2012-04-03 | Savient Pharmaceuticals, Inc. | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
| US20080159976A1 (en) * | 2005-04-11 | 2008-07-03 | Jacob Hartman | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
| WO2008051178A2 (en) | 2006-04-12 | 2008-05-02 | Savient Pharmaceuticals, Inc. | Purification of proteins with cationic surfactant |
| CN102807973A (zh) | 2005-04-11 | 2012-12-05 | 萨文特医药公司 | 尿酸氧化酶的变体形式及其用途 |
| CN1864744B (zh) * | 2005-05-18 | 2010-09-29 | 杭州北斗生物技术有限公司 | 含有尿酸氧化酶的药用制剂 |
| JP2008545665A (ja) * | 2005-05-23 | 2008-12-18 | ユニベルシテ ドゥ ジュネーブ | 高体温による処置のための注入可能な超常磁性ナノ粒子および高体温インプラントを形成するための使用 |
| RU2535038C2 (ru) | 2009-06-25 | 2014-12-10 | Криэлта Фармасьютикалз ЭлЭлСи | Способы и наборы для прогнозирования риска инфузионных реакций и опосредованной антителами потери ответа при терапии пэгилированной уриказой с помощью мониторинга содержания мочевой кислоты в сыворотке крови |
| CN105412942B (zh) * | 2015-12-23 | 2019-02-26 | 沈阳三生制药有限责任公司 | 聚乙二醇化的重组产朊假丝酵母尿酸氧化酶冻干注射剂 |
| EP3443346B1 (en) * | 2016-04-13 | 2023-08-30 | Medimmune, LLC | Use of amino acids as stabilizing compounds in pharmaceutical compositions containing high concentrations of protein-based therapeutic agents |
| EP3538135A4 (en) | 2016-11-11 | 2020-07-29 | Horizon Pharma Rheumatology LLC | POLYTHERAPIES OF PREDNISONE AND URICASE MOLECULES AND THEIR USES |
| US20200237881A1 (en) | 2019-01-30 | 2020-07-30 | Horizon Pharma Rheumatology Llc | Reducing immunogenicity to pegloticase |
| KR101744900B1 (ko) | 2017-01-20 | 2017-06-08 | 주식회사 대웅 | 보툴리눔 독소를 포함하는 안정한 액상 조성물 |
| US12121566B2 (en) | 2019-01-30 | 2024-10-22 | Horizon Therapeutics Usa, Inc. | Methods for treating gout |
| US12269875B2 (en) | 2023-08-03 | 2025-04-08 | Jeff R. Peterson | Gout flare prevention methods using IL-1BETA blockers |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3928137A (en) * | 1971-10-20 | 1975-12-23 | Mallinckrodt Inc | Reagent formulation for uric acid assay |
| US3997470A (en) * | 1971-10-20 | 1976-12-14 | Mallinckrodt, Inc. | Surfactant containing reagent formulations for assaying biological specimens and methods of preparing same |
| JPS51104807A (en) * | 1975-03-12 | 1976-09-17 | Hitachi Ltd | Teepurekoodano ootoribaasuseigyokairo |
| JPS5417027A (en) * | 1977-07-07 | 1979-02-08 | Canon Inc | Image forming system |
| DE3126759A1 (de) * | 1981-07-07 | 1983-01-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung |
| JPS60224499A (ja) * | 1984-04-23 | 1985-11-08 | Toyobo Co Ltd | 安定なウリカ−ゼ製剤 |
| DE3743405A1 (de) * | 1987-05-14 | 1988-11-24 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung von fructosamin |
| JPH0243471A (ja) * | 1988-08-03 | 1990-02-14 | Iwataro Moriyama | 立体駐車装置 |
| WO1992016555A1 (en) | 1991-03-18 | 1992-10-01 | Enzon, Inc. | Hydrazine containing conjugates of polypeptides and glycopolypeptides with polymers |
| CA2130357A1 (en) | 1992-02-18 | 1993-08-19 | Doron Friedman | Dry compositions for preparing submicron emulsions |
-
1995
- 1995-05-11 FR FR9505606A patent/FR2733914B1/fr not_active Expired - Lifetime
-
1996
- 1996-05-07 EA EA199600024A patent/EA000024B1/ru not_active IP Right Cessation
- 1996-05-07 CA CA002175971A patent/CA2175971C/en not_active Expired - Lifetime
- 1996-05-07 AU AU52139/96A patent/AU710288B2/en not_active Expired
- 1996-05-07 IL IL11817196A patent/IL118171A/xx not_active IP Right Cessation
- 1996-05-08 TW TW085105457A patent/TW420614B/zh not_active IP Right Cessation
- 1996-05-09 HU HU9601241A patent/HU225147B1/hu unknown
- 1996-05-09 AT AT96400995T patent/ATE183925T1/de active
- 1996-05-09 DK DK96400995T patent/DK0742013T3/da active
- 1996-05-09 DE DE69604009T patent/DE69604009T2/de not_active Expired - Lifetime
- 1996-05-09 ZA ZA9603683A patent/ZA963683B/xx unknown
- 1996-05-09 EP EP96400995A patent/EP0742013B1/fr not_active Expired - Lifetime
- 1996-05-09 CZ CZ19961350A patent/CZ290799B6/cs not_active IP Right Cessation
- 1996-05-09 PL PL96314147A patent/PL184135B1/pl unknown
- 1996-05-09 ES ES96400995T patent/ES2137635T3/es not_active Expired - Lifetime
- 1996-05-09 SI SI9630093T patent/SI0742013T1/xx unknown
- 1996-05-10 CN CN96110721A patent/CN1090972C/zh not_active Expired - Lifetime
- 1996-05-10 NO NO19961915A patent/NO315261B1/no not_active IP Right Cessation
- 1996-05-10 NZ NZ286554A patent/NZ286554A/en not_active IP Right Cessation
- 1996-05-10 SG SG1996006306A patent/SG42355A1/en unknown
- 1996-05-10 JP JP8152802A patent/JP2950775B2/ja not_active Expired - Lifetime
- 1996-05-10 US US08/644,163 patent/US5811096A/en not_active Expired - Lifetime
-
1997
- 1997-04-24 BR BR1100337-5A patent/BR1100337A/pt active IP Right Grant
-
1999
- 1999-11-18 GR GR990402988T patent/GR3031896T3/el unknown
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