SG52480A1 - Immunogenic compositions against helicobacter infection polypeptides for use in the compositions and nucleic accid sequences encoding said polypeptides - Google Patents

Immunogenic compositions against helicobacter infection polypeptides for use in the compositions and nucleic accid sequences encoding said polypeptides

Info

Publication number
SG52480A1
SG52480A1 SG1996005085A SG1996005085A SG52480A1 SG 52480 A1 SG52480 A1 SG 52480A1 SG 1996005085 A SG1996005085 A SG 1996005085A SG 1996005085 A SG1996005085 A SG 1996005085A SG 52480 A1 SG52480 A1 SG 52480A1
Authority
SG
Singapore
Prior art keywords
polypeptides
fragment
compositions
helicobacter
accid
Prior art date
Application number
SG1996005085A
Other languages
English (en)
Inventor
Agnes Labigne
Sebastien Suerbaum
Richard Ferrero
Jean-Michel Thiberge
Original Assignee
Pasteur Institut
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut, Inst Nat Sante Rech Med filed Critical Pasteur Institut
Publication of SG52480A1 publication Critical patent/SG52480A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG1996005085A 1993-05-19 1994-05-19 Immunogenic compositions against helicobacter infection polypeptides for use in the compositions and nucleic accid sequences encoding said polypeptides SG52480A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93401309 1993-05-19
PCT/EP1993/003259 WO1995014093A1 (fr) 1993-05-19 1993-11-19 Compositions immunogenes dirigees contre les infections par helicobacter, polypeptides utilisables dans ces compositions, et sequences d'acides nucleiques codant ces polypeptides

Publications (1)

Publication Number Publication Date
SG52480A1 true SG52480A1 (en) 1998-09-28

Family

ID=26070083

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996005085A SG52480A1 (en) 1993-05-19 1994-05-19 Immunogenic compositions against helicobacter infection polypeptides for use in the compositions and nucleic accid sequences encoding said polypeptides

Country Status (11)

Country Link
US (1) US6248330B1 (fr)
EP (1) EP0703981B1 (fr)
JP (4) JPH08509873A (fr)
AT (1) ATE364083T1 (fr)
AU (1) AU689779B2 (fr)
CA (1) CA2144307C (fr)
DE (1) DE69434985T2 (fr)
DK (1) DK0703981T3 (fr)
ES (1) ES2288753T3 (fr)
SG (1) SG52480A1 (fr)
WO (2) WO1995014093A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995014093A1 (fr) 1993-05-19 1995-05-26 Institut Pasteur Compositions immunogenes dirigees contre les infections par helicobacter, polypeptides utilisables dans ces compositions, et sequences d'acides nucleiques codant ces polypeptides
US5874405A (en) * 1994-12-16 1999-02-23 Birnbaum; Gary Heat shock protein peptides that share sequences with cyclic nucleotide phosphodiesterase and methods for modulating autoimmune central nervous system disease
WO1996033220A1 (fr) * 1995-04-21 1996-10-24 Csl Limited Antigenes protecteurs d'helicobacter
KR19990008155A (ko) * 1995-04-28 1999-01-25 랜스 고든 다가, 재조합 우레아제 백신
AU5693496A (en) * 1995-05-02 1996-11-21 Institut National De La Sante Et De La Recherche Medicale Immunogenic compositions against helicobacter infection, pol ypeptides for use in the compositions, and nucleic acid sequ ences encoding said polypeptides
JP2000502054A (ja) 1995-11-30 2000-02-22 アグリカルチャー ビクトリア サービシーズ ピーティーワイ．エルティーディー． 治療用および診断用の組成物
GB2307987A (en) * 1995-12-06 1997-06-11 Univ Manchester Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto
GB2324093A (en) * 1996-01-04 1998-10-14 Rican Limited Helicobacter pylori bacterioferritin
DE19630390A1 (de) * 1996-07-26 1998-01-29 Chiron Behring Gmbh & Co Proteine, insbesondere Membranproteine von Helicobacter pylori, ihre Herstellung und Verwendung
EP0835928A1 (fr) * 1996-10-11 1998-04-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin Vaccin vivant d'hélicobacter pylori
US6248551B1 (en) 1997-03-28 2001-06-19 Institut Pasteur Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides
JP3430853B2 (ja) * 1997-04-11 2003-07-28 株式会社ゲン・コーポレーション 胃炎、胃潰瘍および十二指腸潰瘍の予防剤並びに治療剤
AU7537598A (en) * 1997-04-30 1998-11-24 Pasteur Merieux Serums Et Vaccins Dna based anti-(helicobacter) vaccine composition
US5985631A (en) * 1997-09-12 1999-11-16 Oravax-Merieux Co. Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease
US20020151462A1 (en) * 1998-02-19 2002-10-17 Ling Lissolo Helicobacter pylori membrane proteins
US6190667B1 (en) 1998-06-30 2001-02-20 Institut Pasteur Methods of inhibiting Helicobacter pylori
CA2351110A1 (fr) * 2000-07-17 2002-01-17 Akzo Nobel N.V. Vaccin contre les infections a helicobacter felis
GB0021757D0 (en) * 2000-09-04 2000-10-18 Colaco Camilo Vaccine against microbial pathogens
MXPA05000778A (es) * 2002-07-18 2005-08-29 Helix Biopharma Corp Uso de ureasa para inhibir el crecimiento de celulas cancerosas.
US7264800B2 (en) * 2002-07-18 2007-09-04 Helix Biopharma Corporation Method and composition for inhibiting cancer cell growth
CA2612271A1 (fr) 2005-06-16 2006-12-21 Universiteit Gent Vaccins d'immunisation contre helicobacter
US7790143B2 (en) 2005-06-16 2010-09-07 Universiteit Gent Vaccines for immunization against helicobacter
HK1216903A1 (zh) 2013-04-08 2016-12-09 赫利克斯生物药品公司 抗体-尿素酶偶联物在诊断和治疗中的应用
AU2016210551B2 (en) 2015-01-23 2019-03-07 Helix Biopharma Corp. Antibody-urease conjugates for therapeutic purposes
CA3241995A1 (fr) * 2021-12-23 2023-06-29 Luciana ARAMUNI GONCALVES Vaccin a adn contre la leishmaniose
CN116052799B (zh) * 2022-04-06 2026-01-23 大连理工江苏研究院有限公司 一种基于机器学习的幽门螺杆菌抗体药物制备方法及其研发用区块链应用系统

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459041A (en) * 1988-02-18 1995-10-17 Enteric Research Laboratories, Inc. Campylobacter pylori antigens and uses thereof for detection of Campylobacter pylori infection
FR2637612B1 (fr) * 1988-10-06 1993-09-10 Pasteur Institut Sequences de nucleotides codant pour une proteine a activite ureasique
GB8928625D0 (en) * 1989-12-19 1990-02-21 3I Res Expl Ltd H.pylori dna probes
US5262156A (en) * 1991-08-12 1993-11-16 Hycor Biomedical, Inc. Antigenic compositions and their use for the detection of Helicobacter pylori
FR2682122B1 (fr) * 1991-10-03 1995-06-09 Pasteur Institut Nouveaux genes d'helicobacter pylori. leur utilisation pour la preparation de souches recombinantes de h. pylori.
WO1993016723A1 (fr) 1992-02-26 1993-09-02 Vanderbilt University Toxine vacuolisante purifiee issue de helicobacter pylori et methodes d'utilisation de cette toxine
EP0967279B1 (fr) * 1992-03-02 2008-01-02 Novartis Vaccines and Diagnostics S.r.l. Cytotoxine d' Helicobacter pylori utile dans des vaccins et en diagnostique
MX9301706A (es) * 1992-04-13 1994-05-31 Oravax Inc Composicion de vacuna para el tratamiento de la infeccion por helicobacter.
ES2174852T3 (es) * 1992-08-26 2002-11-16 Celtrix Pharma Metodo para el tratamiento sistemico de estados catabolicos y lesiones sistemicas de tejidos.
AU4924893A (en) * 1992-09-16 1994-04-12 Galagen, Inc. Antibody treatment of (helicobacter pylori)
US5972336A (en) 1992-11-03 1999-10-26 Oravax Merieux Co. Urease-based vaccine against helicobacter infection
WO1995014093A1 (fr) 1993-05-19 1995-05-26 Institut Pasteur Compositions immunogenes dirigees contre les infections par helicobacter, polypeptides utilisables dans ces compositions, et sequences d'acides nucleiques codant ces polypeptides
JP3919812B2 (ja) 1993-07-27 2007-05-30 シーエスエル、リミテッド Ｈ．ピロリ関連胃十二指腸疾患の治療
AR003125A1 (es) 1995-06-01 1998-07-08 Astra Ab Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la
WO1996040893A1 (fr) 1995-06-07 1996-12-19 Astra Aktiebolag Sequences d'acide nucleique et d'acides amines concernant helicobacter pylori, utilisees a des fins diagnostiques et therapeutiques

Also Published As

Publication number Publication date
JP2008086316A (ja) 2008-04-17
CA2144307C (fr) 2008-09-02
WO1994026901A1 (fr) 1994-11-24
ES2288753T3 (es) 2008-01-16
EP0703981B1 (fr) 2007-06-06
JP2004337170A (ja) 2004-12-02
WO1995014093A1 (fr) 1995-05-26
EP0703981A1 (fr) 1996-04-03
ATE364083T1 (de) 2007-06-15
DK0703981T3 (da) 2007-10-08
AU689779B2 (en) 1998-04-09
JP3955317B2 (ja) 2007-08-08
AU6929094A (en) 1994-12-12
DE69434985D1 (de) 2007-07-19
JPH08510120A (ja) 1996-10-29
US6248330B1 (en) 2001-06-19
CA2144307A1 (fr) 1994-11-24
JPH08509873A (ja) 1996-10-22
DE69434985T2 (de) 2008-02-21

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