SI20149B - Pharmaceutical compositions of tizoxanide and nitazoxanide - Google Patents

Pharmaceutical compositions of tizoxanide and nitazoxanide Download PDF

Info

Publication number: SI20149B
Authority: SI; Slovenia
Prior art keywords: active ingredient; composition according; particle size; pharmaceutical composition; formula
Prior art date: 1997-05-07

Application number

SI9820037A

Other languages

English (en)

Slovenian (sl)

Other versions

SI20149A (sl

Inventor

Jean-Francois Rossignol

Original Assignee

Romark Lab Lc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-07

Filing date

1998-05-06

Publication date

2001-08-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI20149(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-05-07 Priority claimed from US08/852,447 external-priority patent/US5968961A/en

1997-07-03 Priority claimed from US08/887,809 external-priority patent/US5965590A/en

1997-07-03 Priority claimed from US08/887,810 external-priority patent/US5856348A/en

1998-05-06 Application filed by Romark Lab Lc filed Critical Romark Lab Lc

2000-08-31 Publication of SI20149A publication Critical patent/SI20149A/sl

2001-08-31 Publication of SI20149B publication Critical patent/SI20149B/sl

Links

239000008194 pharmaceutical composition Substances 0.000 title claims abstract 27
YQNQNVDNTFHQSW-UHFFFAOYSA-N acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester Chemical compound CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 YQNQNVDNTFHQSW-UHFFFAOYSA-N 0.000 title claims 2
229960002480 nitazoxanide Drugs 0.000 title claims 2
FDTZUTSGGSRHQF-UHFFFAOYSA-N Desacetyl-nitazoxanide Chemical group OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 FDTZUTSGGSRHQF-UHFFFAOYSA-N 0.000 title 1
239000002245 particle Substances 0.000 claims abstract 39
239000002253 acid Substances 0.000 claims abstract 16
150000001875 compounds Chemical class 0.000 claims abstract 14
239000013543 active substance Substances 0.000 claims abstract 3
239000004480 active ingredient Substances 0.000 claims 32
239000000203 mixture Substances 0.000 claims 21
239000003979 granulating agent Substances 0.000 claims 6
239000007787 solid Substances 0.000 claims 5
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 5
BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims 4
COVZYZSDYWQREU-UHFFFAOYSA-N Busulfan Chemical compound CS(=O)(=O)OCCCCOS(C)(=O)=O COVZYZSDYWQREU-UHFFFAOYSA-N 0.000 claims 4
BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims 4
239000002552 dosage form Substances 0.000 claims 4
239000001630 malic acid Substances 0.000 claims 4
235000011090 malic acid Nutrition 0.000 claims 4
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
239000003814 drug Substances 0.000 claims 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
241001126309 Fasciolopsis Species 0.000 claims 2
241001491880 Heterophyes Species 0.000 claims 2
241000124008 Mammalia Species 0.000 claims 2
241001660197 Metagonimus Species 0.000 claims 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 2
229930006000 Sucrose Natural products 0.000 claims 2
208000004938 Trematode Infections Diseases 0.000 claims 2
239000001913 cellulose Substances 0.000 claims 2
229920002678 cellulose Polymers 0.000 claims 2
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 claims 2
125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
230000003071 parasitic effect Effects 0.000 claims 2
239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
239000005720 sucrose Substances 0.000 claims 2
239000000725 suspension Substances 0.000 claims 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
241000223936 Cryptosporidium parvum Species 0.000 claims 1
241000205707 Cystoisospora belli Species 0.000 claims 1
241000577452 Dicrocoelium Species 0.000 claims 1
241000577456 Dicrocoelium dendriticum Species 0.000 claims 1
241000596569 Encephalitozoon intestinalis Species 0.000 claims 1
241000204939 Fasciola gigantica Species 0.000 claims 1
241000242711 Fasciola hepatica Species 0.000 claims 1
206010061598 Immunodeficiency Diseases 0.000 claims 1
206010023076 Isosporiasis Diseases 0.000 claims 1
229920000881 Modified starch Polymers 0.000 claims 1
241000186367 Mycobacterium avium Species 0.000 claims 1
241000187479 Mycobacterium tuberculosis Species 0.000 claims 1
241000242678 Schistosoma Species 0.000 claims 1
241000242683 Schistosoma haematobium Species 0.000 claims 1
241000242687 Schistosoma intercalatum Species 0.000 claims 1
241000242677 Schistosoma japonicum Species 0.000 claims 1
241000242680 Schistosoma mansoni Species 0.000 claims 1
241001520868 Schistosoma mekongi Species 0.000 claims 1
241000242541 Trematoda Species 0.000 claims 1
239000000654 additive Substances 0.000 claims 1
230000000996 additive effect Effects 0.000 claims 1
229960000541 cetyl alcohol Drugs 0.000 claims 1
125000005456 glyceride group Chemical group 0.000 claims 1
239000006194 liquid suspension Substances 0.000 claims 1
244000005700 microbiome Species 0.000 claims 1
235000019426 modified starch Nutrition 0.000 claims 1
239000006072 paste Substances 0.000 claims 1
239000008253 pharmaceutical paste Substances 0.000 claims 1
235000015067 sauces Nutrition 0.000 claims 1
239000002562 thickening agent Substances 0.000 claims 1
239000000080 wetting agent Substances 0.000 claims 1
208000001388 Opportunistic Infections Diseases 0.000 abstract 1
241000869417 Trematodes Species 0.000 abstract 1
230000001010 compromised effect Effects 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)

SI9820037A 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide SI20149B (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/852,447 US5968961A (en)	1997-05-07	1997-05-07	Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en)	1994-09-08	1997-07-03	Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en)	1994-09-08	1997-07-03	Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
PCT/US1998/009229 WO1998050035A1 (en)	1997-05-07	1998-05-06	Pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (2)

Publication Number	Publication Date
SI20149A SI20149A (sl)	2000-08-31
SI20149B true SI20149B (en)	2001-08-31

Family

ID=27420362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9820037A SI20149B (en)	1997-05-07	1998-05-06	Pharmaceutical compositions of tizoxanide and nitazoxanide

Country Status (34)

Country	Link
EP (2)	EP1005342B1 (pl)
JP (1)	JP3739802B2 (pl)
KR (2)	KR100576646B1 (pl)
CN (2)	CN100515420C (pl)
AP (1)	AP1103A (pl)
AR (1)	AR057242A2 (pl)
AT (2)	ATE281166T1 (pl)
AU (1)	AU740022B2 (pl)
BG (2)	BG109365A (pl)
BR (1)	BR9808722A (pl)
CA (2)	CA2288003C (pl)
CZ (2)	CZ298269B6 (pl)
DE (2)	DE69827417T2 (pl)
DK (2)	DK1222921T3 (pl)
EA (2)	EA002908B1 (pl)
EE (1)	EE04870B1 (pl)
ES (2)	ES2232687T3 (pl)
GE (1)	GEP20032970B (pl)
HU (1)	HU229641B1 (pl)
IL (2)	IL132516A (pl)
IS (1)	IS2087B (pl)
LV (1)	LV12492B (pl)
ME (1)	ME00530B (pl)
NO (2)	NO313983B1 (pl)
NZ (2)	NZ513881A (pl)
OA (1)	OA11169A (pl)
PL (1)	PL193275B1 (pl)
PT (2)	PT1005342E (pl)
RO (1)	RO120605B1 (pl)
SI (1)	SI20149B (pl)
SK (2)	SK283946B6 (pl)
TR (1)	TR199902733T2 (pl)
UA (2)	UA57079C2 (pl)
WO (1)	WO1998050035A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2467321A1 (en)	2004-05-14	2005-11-14	Paul J. Santerre	Polymeric coupling agents and pharmaceutically-active polymers made therefrom
AP2907A (en)	2006-01-09	2014-05-31	Romark Lab Lc	Viral hepatitis treatment
BRPI1007945C8 (pt) *	2009-02-13	2021-05-25	Romark Laboratories Lc	formulação farmacêutica de liberação controlada de nitazoxanida, tizoxanida ou uma combinação dos mesmos, e, comprimido de bicamada para administração oral
EP3078377A3 (en)	2009-05-12	2017-04-05	Romark Laboratories, L.C.	Nitazoxanide and tizoxanide as anti-viral agents
MX341877B (es)	2009-06-26	2016-09-06	Romark Laboratories L C *	Compuestos y métodos para tratar influenza.
MX340846B (es)	2012-01-27	2016-07-28	Rhein Siegfried Sa De Cv	Composición de nitazoxanida mejorada y proceso para prepararla.
CN107105660A (zh) *	2014-11-11	2017-08-29	罗马克实验室有限公司	使用替唑尼特、其类似物或盐的前药的治疗组合物和治疗方法
WO2019148294A1 (en)	2018-02-02	2019-08-08	Interface Biologics, Inc.	Dimeric dexamethasone prodrug compositions and uses thereof
WO2019241376A1 (en)	2018-06-14	2019-12-19	The Trustees Of Columbia University In The City Of New York	Treatment of cognitive disorders using nitazoxanide (ntz), nitazoxanide (ntz) analogs, and metabolites thereof
US12473326B2 (en)	2019-02-01	2025-11-18	Ripple Therapeutics Corporation	Crystalline forms of dexamethasone dimers and uses thereof
US20220347305A1 (en)	2019-08-07	2022-11-03	Ripple Therapeutics Corporation	Controlled release drug dimers
WO2021220061A2 (en)	2020-05-01	2021-11-04	Ripple Therapeutics Corporation	Heterodimer compositions and methods for the treatment of ocular disorders
WO2022130406A1 (en) *	2020-12-15	2022-06-23	Cipla Limited	Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1437800A (en) *	1973-08-08	1976-06-03	Phavic Sprl	Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) *	1978-12-07	1982-02-09	Rossignol Jean F	Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5387598A (en) *	1994-04-13	1995-02-07	Rossignol; Jean-Francois	Composition and galenic formulation suitable for combatting affections of the lower abdomen
US5578621A (en) *	1994-09-08	1996-11-26	Romark Lab Lc	Benzamide derivatives

1998
- 1998-05-06 DE DE69827417T patent/DE69827417T2/de not_active Expired - Lifetime
- 1998-05-06 SK SK1511-99A patent/SK283946B6/sk unknown
- 1998-05-06 EP EP98920285A patent/EP1005342B1/en not_active Expired - Lifetime
- 1998-05-06 RO RO99-01166A patent/RO120605B1/ro unknown
- 1998-05-06 KR KR1020037011334A patent/KR100576646B1/ko not_active Expired - Fee Related
- 1998-05-06 CA CA002288003A patent/CA2288003C/en not_active Expired - Fee Related
- 1998-05-06 CZ CZ0391199A patent/CZ298269B6/cs not_active IP Right Cessation
- 1998-05-06 ES ES02002887T patent/ES2232687T3/es not_active Expired - Lifetime
- 1998-05-06 CN CNB2004100459536A patent/CN100515420C/zh not_active Expired - Fee Related
- 1998-05-06 AP APAP/P/1999/001675A patent/AP1103A/en active
- 1998-05-06 SK SK708-2003A patent/SK283947B6/sk unknown
- 1998-05-06 PL PL336805A patent/PL193275B1/pl not_active IP Right Cessation
- 1998-05-06 NZ NZ513881A patent/NZ513881A/xx not_active IP Right Cessation
- 1998-05-06 DE DE69809928T patent/DE69809928T2/de not_active Expired - Lifetime
- 1998-05-06 EP EP02002887A patent/EP1222921B1/en not_active Expired - Lifetime
- 1998-05-06 HU HU0003330A patent/HU229641B1/hu not_active IP Right Cessation
- 1998-05-06 TR TR1999/02733T patent/TR199902733T2/xx unknown
- 1998-05-06 IL IL13251698A patent/IL132516A/xx not_active IP Right Cessation
- 1998-05-06 ES ES98920285T patent/ES2150404T3/es not_active Expired - Lifetime
- 1998-05-06 AT AT02002887T patent/ATE281166T1/de active
- 1998-05-06 KR KR10-1999-7009930A patent/KR100426657B1/ko not_active Expired - Lifetime
- 1998-05-06 DK DK02002887T patent/DK1222921T3/da active
- 1998-05-06 BR BR9808722-3A patent/BR9808722A/pt not_active IP Right Cessation
- 1998-05-06 DK DK98920285T patent/DK1005342T3/da active
- 1998-05-06 CN CNB988049007A patent/CN1158074C/zh not_active Expired - Fee Related
- 1998-05-06 IL IL15579998A patent/IL155799A/en not_active IP Right Cessation
- 1998-05-06 EE EEP199900578A patent/EE04870B1/xx unknown
- 1998-05-06 EA EA199901012A patent/EA002908B1/ru not_active IP Right Cessation
- 1998-05-06 WO PCT/US1998/009229 patent/WO1998050035A1/en not_active Ceased
- 1998-05-06 ME MEP-2008-877A patent/ME00530B/me unknown
- 1998-05-06 CZ CZ20060366A patent/CZ298270B6/cs not_active IP Right Cessation
- 1998-05-06 CA CA002418634A patent/CA2418634C/en not_active Expired - Fee Related
- 1998-05-06 NZ NZ500149A patent/NZ500149A/en not_active IP Right Cessation
- 1998-05-06 JP JP54843798A patent/JP3739802B2/ja not_active Expired - Fee Related
- 1998-05-06 PT PT98920285T patent/PT1005342E/pt unknown
- 1998-05-06 AU AU72895/98A patent/AU740022B2/en not_active Ceased
- 1998-05-06 AT AT98920285T patent/ATE228839T1/de active
- 1998-05-06 GE GEAP19985109A patent/GEP20032970B/en unknown
- 1998-05-06 SI SI9820037A patent/SI20149B/sl not_active IP Right Cessation
- 1998-05-06 EA EA200100956A patent/EA002920B1/ru not_active IP Right Cessation
- 1998-05-06 PT PT02002887T patent/PT1222921E/pt unknown
- 1998-06-05 UA UA99126626A patent/UA57079C2/uk unknown
- 1998-12-06 BG BG109365A patent/BG109365A/en unknown
1999
- 1999-10-19 IS IS5223A patent/IS2087B/is unknown
- 1999-10-29 OA OA9900239A patent/OA11169A/en unknown
- 1999-11-04 NO NO19995406A patent/NO313983B1/no not_active IP Right Cessation
- 1999-12-01 LV LVP-99-170A patent/LV12492B/en unknown
- 1999-12-06 BG BG103958A patent/BG64973B1/bg unknown
2002
- 2002-04-18 NO NO20021832A patent/NO335781B1/no not_active IP Right Cessation
2003
- 2003-04-04 UA UA2003042974A patent/UA74388C2/uk unknown
2006
- 2006-12-14 AR ARP060105534A patent/AR057242A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0003330A2 (hu)	2001-05-28
IL155799A0 (en)	2003-12-23
CN1552322A (zh)	2004-12-08
NO995406L (no)	2000-01-04
JP3739802B2 (ja)	2006-01-25
CN1158074C (zh)	2004-07-21
KR100576646B1 (ko)	2006-05-08
AU740022B2 (en)	2001-10-25
EP1222921B1 (en)	2004-11-03
EA199901012A1 (ru)	2000-08-28
NO313983B1 (no)	2003-01-13
DK1222921T3 (da)	2005-03-07
SK151199A3 (en)	2000-07-11
SK283946B6 (sk)	2004-05-04
EP1005342B1 (en)	2002-12-04
SI20149A (sl)	2000-08-31
CZ298269B6 (cs)	2007-08-08
NO20021832L (no)	2000-01-04
NO20021832D0 (no)	2002-04-18
NZ513881A (en)	2002-10-25
UA74388C2 (uk)	2005-12-15
DK1005342T3 (da)	2003-03-24
CZ298270B6 (cs)	2007-08-08
PT1005342E (pt)	2003-02-28
IS2087B (is)	2006-03-15
AU7289598A (en)	1998-11-27
EP1005342A4 (en)	2001-02-07
ES2150404T1 (es)	2000-12-01
EA002920B1 (ru)	2002-10-31
OA11169A (en)	2003-04-25
HU229641B1 (en)	2014-03-28
EE9900578A (et)	2000-08-15
GEP20032970B (en)	2003-05-27
BG109365A (en)	2006-08-31
AP1103A (en)	2002-09-04
CA2418634A1 (en)	1998-11-12
ME00530B (me)	2011-10-10
DE69827417D1 (de)	2004-12-09
IS5223A (is)	1999-10-19
KR20010020322A (ko)	2001-03-15
LV12492B (en)	2001-01-20
EP1005342A1 (en)	2000-06-07
NZ500149A (en)	2001-11-30
KR20040004544A (ko)	2004-01-13
IL132516A (en)	2003-12-10
PL336805A1 (en)	2000-07-17
IL132516A0 (en)	2001-03-19
BG64973B1 (bg)	2006-11-30
NO995406D0 (no)	1999-11-04
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