SI21302A - Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino - Google Patents

Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino Download PDF

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Publication number
SI21302A
SI21302A SI200200244A SI200200244A SI21302A SI 21302 A SI21302 A SI 21302A SI 200200244 A SI200200244 A SI 200200244A SI 200200244 A SI200200244 A SI 200200244A SI 21302 A SI21302 A SI 21302A
Authority
SI
Slovenia
Prior art keywords
gas
pharmaceutical
active ingredient
amorphous active
stable
Prior art date
Application number
SI200200244A
Other languages
English (en)
Slovenian (sl)
Inventor
Rok Grahek
Andrej Bastarda
Mateja Salobir
Original Assignee
LEK farmacevtska dru�ba d.d.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32091984&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI21302(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LEK farmacevtska dru�ba d.d. filed Critical LEK farmacevtska dru�ba d.d.
Priority to SI200200244A priority Critical patent/SI21302A/sl
Priority to TW092127769A priority patent/TWI320709B/zh
Priority to DE60312049T priority patent/DE60312049T2/de
Priority to PCT/EP2003/011265 priority patent/WO2004032920A1/fr
Priority to AU2003280361A priority patent/AU2003280361B2/en
Priority to PT03770970T priority patent/PT1608362E/pt
Priority to CZ200718450U priority patent/CZ17610U1/cs
Priority to AT03770970T priority patent/ATE354362T1/de
Priority to DE20321455U priority patent/DE20321455U1/de
Priority to MEP-2008-842A priority patent/ME00514B/fr
Priority to ES03770970T priority patent/ES2285205T3/es
Priority to UAA200504398A priority patent/UA85544C2/ru
Priority to EP03770970A priority patent/EP1608362B1/fr
Priority to ARP030103710A priority patent/AR041588A1/es
Priority to DK03770970T priority patent/DK1608362T3/da
Priority to SI200330805T priority patent/SI1608362T1/sl
Priority to CNB2003801009910A priority patent/CN100372529C/zh
Priority to SK5006-2007U priority patent/SK5233Y1/sk
Priority to US10/683,683 priority patent/US20040077708A1/en
Priority to RU2005114485/15A priority patent/RU2358727C2/ru
Priority to YU20050273A priority patent/RS51819B/sr
Publication of SI21302A publication Critical patent/SI21302A/sl
Priority to DK200700025U priority patent/DK200700025U4/da
Priority to FI20070036U priority patent/FI7617U1/fi
Priority to AT0010907U priority patent/AT10424U1/de
Priority to CY20071100681T priority patent/CY1106608T1/el
Priority to US11/923,059 priority patent/US20090012150A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SI200200244A 2002-10-11 2002-10-11 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino SI21302A (sl)

Priority Applications (26)

Application Number Priority Date Filing Date Title
SI200200244A SI21302A (sl) 2002-10-11 2002-10-11 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
TW092127769A TWI320709B (en) 2002-10-11 2003-10-07 Stabilized pharmaceutical composition comprising an amorphous active substance
YU20050273A RS51819B (sr) 2002-10-11 2003-10-10 Stabilizovani farmaceutski preparat koji sadrži amorfnu aktivnu supstancu
EP03770970A EP1608362B1 (fr) 2002-10-11 2003-10-10 Preparation pharmaceutique stabilisee renfermant une substance amorphe active
SI200330805T SI1608362T1 (sl) 2002-10-11 2003-10-10 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
AU2003280361A AU2003280361B2 (en) 2002-10-11 2003-10-10 Stabilized pharmaceutical preparation comprising an amorphous active substance
PT03770970T PT1608362E (pt) 2002-10-11 2003-10-10 Preparação farmacêutica estabilizada incluindo uma substância activa amorfa
CZ200718450U CZ17610U1 (cs) 2002-10-11 2003-10-10 Stabilizovaný farmaceutický prípravek obsahující amorfní kalcium-atorvastatin
AT03770970T ATE354362T1 (de) 2002-10-11 2003-10-10 Stabilisierte pharmazeutische zusammensetzung enthaltend einen amorphen wirkstoff
DE20321455U DE20321455U1 (de) 2002-10-11 2003-10-10 Stabilisiertes pharmazeutisches Erzeugnis, das einen amorphen Wirkstoff enthält
MEP-2008-842A ME00514B (fr) 2002-10-11 2003-10-10 Preparation pharmaceutique stabilisee renfermant une substance amorphe active
ES03770970T ES2285205T3 (es) 2002-10-11 2003-10-10 Preparacion farmaceutica estable que comprende una substancia activa amorfa.
UAA200504398A UA85544C2 (ru) 2002-10-11 2003-10-10 Стабилизированный фармацевтический препарат аморфного аторвастатина кальция
DE60312049T DE60312049T2 (de) 2002-10-11 2003-10-10 Stabilisierte pharmazeutische zusammensetzung enthaltend einen amorphen wirkstoff
ARP030103710A AR041588A1 (es) 2002-10-11 2003-10-10 Composicion farmaceutica estabilizada que comprende una sustancia activa amorfa
DK03770970T DK1608362T3 (da) 2002-10-11 2003-10-10 Stabiliseret farmaceutisk præparat indeholdende en amorf aktiv forbindelse
PCT/EP2003/011265 WO2004032920A1 (fr) 2002-10-11 2003-10-10 Preparation pharmaceutique stabilisee renfermant une substance amorphe active
CNB2003801009910A CN100372529C (zh) 2002-10-11 2003-10-10 包含无定形活性物质的稳定药物制剂
SK5006-2007U SK5233Y1 (en) 2002-10-11 2003-10-10 Stabilized pharmaceutical preparation comprising amorphous atorvastatin calcium and method for packaging and stabilisation thereof
US10/683,683 US20040077708A1 (en) 2002-10-11 2003-10-10 Stablized pharmaceutical composition comprising an amorphous active substance
RU2005114485/15A RU2358727C2 (ru) 2002-10-11 2003-10-10 Стабилизированный фармацевтический препарат, включающий аморфное активное вещество
DK200700025U DK200700025U4 (da) 2002-10-11 2007-01-25 Stabiliseret farmaceutisk præparat indeholdende en amorf aktiv forbindelse
FI20070036U FI7617U1 (fi) 2002-10-11 2007-01-26 Amorfisen aktiivisen ainesosan stabiloitu farmaseuttinen valmiste
AT0010907U AT10424U1 (de) 2002-10-11 2007-02-20 Fertigarzneimittel, enthaltend ein in inertgas gelagertes, amorphes atorvastatin-ca
CY20071100681T CY1106608T1 (el) 2002-10-11 2007-05-21 Σταθεροποιημενα φαρμακευτικα σκευασματα που περιλαμβανουν μια αμορφη δραστικη ουσια
US11/923,059 US20090012150A1 (en) 2002-10-11 2007-10-24 Stablized Pharmaceutical Composition Comprising an Amorphous Active Substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200200244A SI21302A (sl) 2002-10-11 2002-10-11 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino

Publications (1)

Publication Number Publication Date
SI21302A true SI21302A (sl) 2004-04-30

Family

ID=32091984

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200200244A SI21302A (sl) 2002-10-11 2002-10-11 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino
SI200330805T SI1608362T1 (sl) 2002-10-11 2003-10-10 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200330805T SI1608362T1 (sl) 2002-10-11 2003-10-10 Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino

Country Status (21)

Country Link
US (2) US20040077708A1 (fr)
EP (1) EP1608362B1 (fr)
CN (1) CN100372529C (fr)
AR (1) AR041588A1 (fr)
AT (2) ATE354362T1 (fr)
AU (1) AU2003280361B2 (fr)
CY (1) CY1106608T1 (fr)
CZ (1) CZ17610U1 (fr)
DE (2) DE60312049T2 (fr)
DK (2) DK1608362T3 (fr)
ES (1) ES2285205T3 (fr)
FI (1) FI7617U1 (fr)
ME (1) ME00514B (fr)
PT (1) PT1608362E (fr)
RS (1) RS51819B (fr)
RU (1) RU2358727C2 (fr)
SI (2) SI21302A (fr)
SK (1) SK5233Y1 (fr)
TW (1) TWI320709B (fr)
UA (1) UA85544C2 (fr)
WO (1) WO2004032920A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8044086B2 (en) 2004-07-16 2011-10-25 Lek Pharmaceuticals D.D. Oxidative degradation products of atorvastatin calcium

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SI20109A (sl) * 1998-12-16 2000-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Stabilna farmacevtska formulacija
US7411075B1 (en) * 2000-11-16 2008-08-12 Teva Pharmaceutical Industries Ltd. Polymorphic form of atorvastatin calcium
IL156055A0 (en) 2000-11-30 2003-12-23 Teva Pharma Novel crystal forms of atorvastatin hemi calcium and processes for their preparation as well as novel processes for preparing other forms
US7501450B2 (en) 2000-11-30 2009-03-10 Teva Pharaceutical Industries Ltd. Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
JP4739672B2 (ja) 2001-12-21 2011-08-03 ネクター セラピューティクス 湿気のバリアを有するカプセルパッケージ
US20080171784A1 (en) * 2003-08-05 2008-07-17 Zentiva, A.S. Methods For the Stabilization of Atorvastatin
CA2560252C (fr) 2004-03-17 2009-08-04 Ranbaxy Laboratories Limited Procede de production d'atorvastatine calcique sous forme amorphe
US20080009540A1 (en) * 2004-09-30 2008-01-10 Srinivasulu Gudipati Amorphous Atorvastatin Calcium
JP2008521878A (ja) * 2004-12-02 2008-06-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 非晶質アトルバスタチンの医薬組成物及びその製造のための方法
TWI318571B (en) * 2005-06-10 2009-12-21 Lilly Co Eli Formulation of a thienopyridine platelet aggregation inhibitor
US20090216029A1 (en) * 2005-09-16 2009-08-27 Yatendra Kumar Process for the production of atorvastatin calcium in amorphous form
CA2547216A1 (fr) * 2005-09-21 2007-03-21 Renuka D. Reddy Procede de recuit de l'atorvastatine amorphe
US20090247603A1 (en) 2005-12-23 2009-10-01 Orbus Pharma, Inc. Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor
EP1810667A1 (fr) * 2006-01-20 2007-07-25 KRKA, tovarna zdravil, d.d., Novo mesto Composition pharmaceutique contenant de l'atorvastatin amorphé
GB2450117A (en) * 2007-06-13 2008-12-17 Reckitt Benckiser Healthcare A water- and oxygen-occlusive blister tablet pack
KR20100051667A (ko) * 2007-07-27 2010-05-17 씨아이피엘에이 엘티디. 약제학적 조성물 및 그의 제조방법
US20090071855A1 (en) * 2007-09-14 2009-03-19 Bahuguna Sumit Packaging for amorphous statins and compositions thereof
EP2127628A1 (fr) * 2008-05-27 2009-12-02 Ranbaxy Laboratories Limited Emballage de dose d'unité
US20120244220A1 (en) 2009-12-25 2012-09-27 Sawai Pharmaceutical Co., Ltd. Atrovastatin-containing coated preparation
IN2014CN04119A (fr) 2011-11-15 2015-07-10 Reddys Lab Ltd Dr
CN102525942A (zh) * 2012-01-05 2012-07-04 金陵药业股份有限公司 一种阿托伐他汀钙肠溶微丸及其制备方法
CA3011685C (fr) * 2015-02-03 2021-07-20 Kadmon Pharmaceuticals, Llc Formulations stables de trientine
US10905113B2 (en) 2015-11-12 2021-02-02 Regents Of The University Of Minnesota Compositions and method for storing liquid biospecimens
EP3184103A1 (fr) 2015-12-21 2017-06-28 Hexal AG Composition pharmaceutique comprenant de l'atorvastatine ou un sel de celui-ci
US11968975B2 (en) 2019-04-30 2024-04-30 Regents Of The University Of Minnesota Compositions and methods for storing liquid biospecimens

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8044086B2 (en) 2004-07-16 2011-10-25 Lek Pharmaceuticals D.D. Oxidative degradation products of atorvastatin calcium

Also Published As

Publication number Publication date
FI7617U1 (fi) 2007-09-28
SI1608362T1 (sl) 2007-12-31
AU2003280361A1 (en) 2004-05-04
RS20050273A (sr) 2007-06-04
AU2003280361B2 (en) 2009-02-26
US20090012150A1 (en) 2009-01-08
FIU20070036U0 (fi) 2007-01-26
SK50062007U1 (en) 2009-03-05
RU2005114485A (ru) 2006-01-27
ME00514B (fr) 2011-10-10
EP1608362A1 (fr) 2005-12-28
AR041588A1 (es) 2005-05-26
WO2004032920A1 (fr) 2004-04-22
DK1608362T3 (da) 2007-05-14
RS51819B (sr) 2011-12-31
CY1106608T1 (el) 2012-01-25
CZ17610U1 (cs) 2007-06-18
SK5233Y1 (en) 2009-09-07
TWI320709B (en) 2010-02-21
EP1608362B1 (fr) 2007-02-21
CN1703215A (zh) 2005-11-30
CN100372529C (zh) 2008-03-05
ES2285205T3 (es) 2007-11-16
PT1608362E (pt) 2007-05-31
DK200700025U1 (da) 2007-06-08
DE20321455U1 (de) 2007-05-24
TW200501947A (en) 2005-01-16
DE60312049D1 (de) 2007-04-05
DK200700025U4 (da) 2008-03-14
DE60312049T2 (de) 2007-10-04
RU2358727C2 (ru) 2009-06-20
ATE354362T1 (de) 2007-03-15
US20040077708A1 (en) 2004-04-22
AT10424U1 (de) 2009-03-15
UA85544C2 (ru) 2009-02-10

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