SI21542A - Formulacija amino kislin in riboflavina, koristna za zmanjšanje toksičnih učinkov citotoksične kemoterapije - Google Patents

Formulacija amino kislin in riboflavina, koristna za zmanjšanje toksičnih učinkov citotoksične kemoterapije Download PDF

Info

Publication number
SI21542A
SI21542A SI200220037A SI200220037A SI21542A SI 21542 A SI21542 A SI 21542A SI 200220037 A SI200220037 A SI 200220037A SI 200220037 A SI200220037 A SI 200220037A SI 21542 A SI21542 A SI 21542A
Authority
SI
Slovenia
Prior art keywords
concentration
riboflavin
glycine
threonine
serine
Prior art date
Application number
SI200220037A
Other languages
English (en)
Slovenian (sl)
Inventor
Stanislav R. Burzynski
Original Assignee
Stanislav R. Burzynski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stanislav R. Burzynski filed Critical Stanislav R. Burzynski
Publication of SI21542A publication Critical patent/SI21542A/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200220037A 2001-11-27 2002-11-21 Formulacija amino kislin in riboflavina, koristna za zmanjšanje toksičnih učinkov citotoksične kemoterapije SI21542A (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/995,010 US20030105104A1 (en) 2001-11-27 2001-11-27 Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy
PCT/US2002/037354 WO2003045372A1 (en) 2001-11-27 2002-11-21 Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy

Publications (1)

Publication Number Publication Date
SI21542A true SI21542A (sl) 2005-02-28

Family

ID=25541300

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200220037A SI21542A (sl) 2001-11-27 2002-11-21 Formulacija amino kislin in riboflavina, koristna za zmanjšanje toksičnih učinkov citotoksične kemoterapije

Country Status (21)

Country Link
US (2) US20030105104A1 (de)
EP (1) EP1450781B1 (de)
JP (1) JP4614660B2 (de)
KR (1) KR100953483B1 (de)
CN (1) CN100358527C (de)
AT (1) ATE330595T1 (de)
BR (1) BR0214430A (de)
CA (1) CA2468133C (de)
DE (1) DE60212693T2 (de)
EA (1) EA009516B1 (de)
HU (1) HU230986B1 (de)
IL (2) IL162141A0 (de)
MX (1) MXPA04004994A (de)
NO (1) NO332858B1 (de)
NZ (1) NZ532833A (de)
PL (1) PL353656A1 (de)
RO (1) RO121173B1 (de)
SI (1) SI21542A (de)
UA (1) UA78977C2 (de)
WO (1) WO2003045372A1 (de)
ZA (1) ZA200404115B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060293335A1 (en) * 2002-08-02 2006-12-28 Qishou Xu Riboflavin derivative and its manufacture and uses
US20070248693A1 (en) * 2003-08-02 2007-10-25 Elizabeth Mazzio Nutraceutical composition and method of use for treatment / prevention of cancer
US20060035981A1 (en) * 2003-08-02 2006-02-16 Mazzio Elizabeth A Inhibition of anaerobic glucose metabolism and corresponding composition as a natural non-toxic approach to cancer treatment
RU2240788C1 (ru) * 2003-09-09 2004-11-27 Воронежская государственная медицинская академия им. Н.Н. Бурденко Детоксикационное средство
PT2319581E (pt) 2004-11-26 2015-06-30 Ucl Business Plc Composições compreendendo ornitina e fenilacetato ou fenilbutirato para tratamento de encefalopatia hepática
KR101265377B1 (ko) * 2005-09-19 2013-05-20 옴니비젼 씨디엠 옵틱스 인코퍼레이티드 태스크-기반의 이미징 시스템
AU2007237685B2 (en) 2006-03-15 2012-08-09 Suntory Holdings Limited Compositions containing riboflavin and sesamin-class compounds
WO2008050836A1 (en) * 2006-10-25 2008-05-02 Ajinomoto Co., Inc. Agent for ameliorating adverse side-effect of chemotherapeutic agent
WO2008105384A1 (ja) * 2007-02-26 2008-09-04 Kyowa Hakko Bio Co., Ltd. シトルリン含有錠剤
EP3342409A1 (de) 2007-03-15 2018-07-04 Suntory Holdings Limited Mittel gegen müdigkeit
WO2010011927A1 (en) 2008-07-25 2010-01-28 Noventis, Inc. Compositions and methods for the prevention and treatment of cardiovascular diseases
AU2014200578B2 (en) * 2008-09-19 2016-08-11 Société des Produits Nestlé S.A. Nutritional support to prevent or moderate bone marrow paralysis or neutropenia during anti-cancer treatment
WO2010033425A2 (en) 2008-09-19 2010-03-25 Nestec S.A. Nutritional support to prevent or moderate bone marrow paralysis or neutropenia during anti-cancer treatment
CN106810464B (zh) 2009-04-03 2019-01-22 欧塞拉治疗有限公司 L-鸟氨酸苯乙酸盐及其制备方法
ES2517340T3 (es) 2009-06-08 2014-11-03 Ucl Business Plc Tratamiento de la hipertensión portal usando L-ornitina y fenilacetato
US8449512B2 (en) 2010-04-09 2013-05-28 Davinci Biomedical Research Products Inc. Stoma stabilitating device and method
EP2397458A1 (de) * 2010-06-21 2011-12-21 Lunamed AG Organische Salze und Co-Kristalle von Phenylbuttersäure
CN108420827A (zh) * 2010-07-22 2018-08-21 雷文制药有限公司 包含磁偶极子稳定化溶液的组合物及其用途
JP6000253B2 (ja) * 2010-09-24 2016-09-28 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 胃腸機能を改善するための材料および方法
EP2625162B1 (de) 2010-10-06 2019-03-13 Ocera Therapeutics, Inc. Verfahren zur herstellung von l-ornithin-phenyl-acetat
CN103429234B (zh) 2010-12-10 2016-10-05 布罗迪健康科学有限公司 茉莉酮酸酯治疗膀胱功能障碍的用途
WO2012111790A1 (ja) * 2011-02-17 2012-08-23 味の素株式会社 化学療法剤の抗腫瘍活性増強剤
JP6082737B2 (ja) * 2011-07-07 2017-02-15 リサーチ キャンサー インスティテュート オブ アメリカResearch Cancer Institute Of America がんを治療するためのシステム、方法、および製剤
MX361647B (es) 2013-03-11 2018-12-13 Univ Florida Materiales y métodos para mejorar la función pulmonar y para la prevención y/o tratamiento de complicaciones pulmonares inducidas por radiación.
RU2016117205A (ru) * 2013-11-08 2017-12-11 Легаси Хелскеар Лтд Способ ведения пациентов, больных раком и сопутствующими заболеваниями, связанными с лечением рака
JP6598425B2 (ja) * 2014-02-27 2019-10-30 花王株式会社 疲労の評価方法
KR20230018526A (ko) 2014-11-24 2023-02-07 유씨엘 비즈니스 리미티드 암모니아-저감 치료를 이용한 간성상세포 활성화와 연관된 질병의 치료
JP6990170B2 (ja) 2015-08-18 2022-01-12 オセラ セラピューティクス, インコーポレイテッド L-オルニチンをフェニルアセテートおよびフェニルブチレートのうちの少なくとも1つと組み合わせて用いる筋肉喪失の治療および予防
US11219611B2 (en) 2015-11-13 2022-01-11 Ocera Therapeutics, Inc. Formulations of L-ornithine phenylacetate
CN105495582A (zh) * 2015-12-11 2016-04-20 北京康比特体育科技股份有限公司 一款抗疲劳、促恢复的保健食品氨基酸组合物
MX389665B (es) 2017-05-11 2025-03-20 Ocera Therapeutics Inc Procesos para producir fenilacetato de l-ornitina

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535049A (en) * 1978-09-04 1980-03-11 Otsuka Pharmaceut Factory Inc Amino acid transfusion for cancerous patient
JPS58126767A (ja) * 1982-01-22 1983-07-28 Ajinomoto Co Inc 肝臓病患者用栄養組成物
EP0220537B1 (de) * 1985-10-23 1990-07-25 Dr. Kurt Mulli Nachf. GmbH & Co. KG Thymusextraktfraktionen enthaltende pharmazeutische Zusammensetzung
US5045468A (en) 1986-12-12 1991-09-03 Cell Enterprises, Inc. Protein-free culture medium which promotes hybridoma growth
ATE113441T1 (de) * 1989-10-02 1994-11-15 Sandoz Nutrition Ltd Proteinhydrolysaten.
US5292773A (en) 1990-02-14 1994-03-08 Hirsch Gerald P Treating aids and HIV infection with methionine
CA2143420C (en) * 1992-12-23 1999-01-19 Phyllis J. B. Acosta Medical foods for the nutritional support of infant/toddler metabolic diseases
US5571783A (en) * 1993-03-09 1996-11-05 Clintec Nutrition Company Composition and method for treating patients with hepatic disease
FR2705765B1 (fr) * 1993-04-29 1995-08-18 Eurofours Sa Porte de four.
NZ248605A (en) * 1993-05-28 1994-12-22 Abbott Lab Enteral nutritional product comprising protein and fat
US5547927A (en) * 1993-05-28 1996-08-20 Abbott Laboratories Enteral nutritional product for patients undergoing radiation therapy and/or chemotherapy
US5719133A (en) * 1994-09-21 1998-02-17 Novartis Nutrition Ag Adolescent dietary composition
US5656608B1 (en) 1995-02-23 2000-09-26 Novartis Nutrition Ltd Amino acid compositions and methods of treatment using same
US5728678A (en) * 1995-06-06 1998-03-17 Nestec Ltd. Method and composition for providing nutrition to a renal failure patient
US5776913A (en) 1995-10-10 1998-07-07 Colgate Palmolive Company Therapeutic diet for metabolic abnormalities found in animals with lymphoma
DE69734713T2 (de) * 1996-05-14 2006-07-06 Burzynski, Stanislaw R., Houston Liposomale antineoplaston therapie mit bemerkenswert verbesserter antineoplastischer aktivität
US5817927A (en) * 1997-04-11 1998-10-06 Betzdearborn Inc. Method and apparatus for monitoring water process equipment
US5817695A (en) * 1997-12-24 1998-10-06 Pellico; Michael A. Nutritional product with high fat, low carbohydrate and amino acid imbalance
PT1062879E (pt) 1999-06-26 2003-12-31 Braun Melsungen Ag Solucao aquosa para nutricao parenteral
GB0009056D0 (en) * 2000-04-12 2000-05-31 Nestle Sa Composition comprising free amino acids
US6377094B1 (en) * 2002-03-25 2002-04-23 Oak Technology, Inc. Arbitrary waveform synthesizer using a free-running ring oscillator

Also Published As

Publication number Publication date
DE60212693D1 (de) 2006-08-03
CN1596109A (zh) 2005-03-16
NO20042364L (no) 2004-06-07
KR100953483B1 (ko) 2010-04-16
BR0214430A (pt) 2004-11-03
NZ532833A (en) 2006-12-22
DE60212693T2 (de) 2007-07-05
JP4614660B2 (ja) 2011-01-19
ZA200404115B (en) 2005-11-30
ATE330595T1 (de) 2006-07-15
NO332858B1 (no) 2013-01-21
RO121173B1 (ro) 2007-01-30
KR20040065565A (ko) 2004-07-22
HUP0402240A3 (en) 2012-09-28
US7427619B2 (en) 2008-09-23
MXPA04004994A (es) 2005-04-08
UA78977C2 (en) 2007-05-10
US20050182064A1 (en) 2005-08-18
EA200400737A1 (ru) 2004-12-30
IL162141A0 (en) 2005-11-20
WO2003045372A1 (en) 2003-06-05
HU230986B1 (hu) 2019-08-28
IL162141A (en) 2009-05-04
CA2468133C (en) 2011-02-22
CN100358527C (zh) 2008-01-02
EP1450781A1 (de) 2004-09-01
US20030105104A1 (en) 2003-06-05
EA009516B1 (ru) 2008-02-28
HUP0402240A2 (hu) 2005-02-28
AU2002352843A1 (en) 2003-06-10
EP1450781B1 (de) 2006-06-21
JP2005518361A (ja) 2005-06-23
PL353656A1 (en) 2003-06-02
CA2468133A1 (en) 2003-06-05

Similar Documents

Publication Publication Date Title
KR100953483B1 (ko) 세포독성 화학요법의 독성효과 감소에 유용한 아미노산 및리보플라빈 조성물
AUSTGEN et al. The effects of glutamine-enriched total parenteral nutrition on tumor growth and host tissues
EP0679081B1 (de) Pharmazeutische zusammensetzungen zur prävention und behandlung von krebserkrankungen und verfahren für ihre herstellung
CA2499199A1 (en) Leucine-enriched nutritional compositions
US5276018A (en) Composition comprising amino acids and methods for decreasing muscle breakdown
US20100234308A1 (en) Wake-up remedy
US9119416B2 (en) Muscle fatigue remedy
KR102295317B1 (ko) 근육 질환 예방 및 치료용 조성물
WO1999017612A1 (en) Serotonin containing formulation for oral administration and method of use
US6479068B1 (en) Therapeutic nutrient regimen for alleviating mucositis, stomatitis and cachexia in oncology patients
JPH06256184A (ja) 癌患者用アミノ酸製剤
WO1999016433A1 (en) Remedy for hepatopathy
AU2002352843B2 (en) Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy
Hilgers et al. A phase I and pharmacokinetic study of irofulven and cisplatin administered in a 30-min infusion every two weeks to patients with advanced solid tumors
JPH06256186A (ja) 癌用アミノ酸製剤
JP3534535B2 (ja) グルタミン含有栄養液
CN106806382A (zh) 抗癌组合物
WO2001052828A2 (en) Glutamine prevention of delayed-onset irinotecan-induced diarrhea
JP5477413B2 (ja) 分岐鎖アミノ酸の心不全適応
LLLGGGGG LGGGGGGGGGS GGGGGGG LLLLLGLL GGGGL GGG LLLL
HK40024470A (en) Use of amino acid supplementation for improved muscle protein synthesis
JPS59184124A (ja) 腎不全、糖尿病及び糖尿病性腎症におけるエネルギー代謝改善剤

Legal Events

Date Code Title Description
OO00 Grant of patent

Effective date: 20050104

KO00 Lapse of patent

Effective date: 20121126