UA78977C2 - Drug comprising amino acids and riboflavin for reducing toxicity of anticancer chemotherapy - Google Patents

Drug comprising amino acids and riboflavin for reducing toxicity of anticancer chemotherapy Download PDF

Info

Publication number: UA78977C2
Authority: UA; Ukraine
Prior art keywords: cancer; amino acids; patients; administration; chemotherapy
Prior art date: 2001-11-27

Application number

UA20040605059A

Other languages

English (en)

Ukrainian (uk)

Inventor

Stanislaw R Burzynskii

Original Assignee

Stanislaw R Burzynskii

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-27

Filing date

2002-11-21

Publication date

2007-05-10

2002-11-21 Application filed by Stanislaw R Burzynskii filed Critical Stanislaw R Burzynskii

2007-05-10 Publication of UA78977C2 publication Critical patent/UA78977C2/uk

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Oncology (AREA)
Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

UA20040605059A 2001-11-27 2002-11-21 Drug comprising amino acids and riboflavin for reducing toxicity of anticancer chemotherapy UA78977C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/995,010 US20030105104A1 (en)	2001-11-27	2001-11-27	Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy
PCT/US2002/037354 WO2003045372A1 (en)	2001-11-27	2002-11-21	Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy

Publications (1)

Publication Number	Publication Date
UA78977C2 true UA78977C2 (en)	2007-05-10

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UA20040605059A UA78977C2 (en)	2001-11-27	2002-11-21	Drug comprising amino acids and riboflavin for reducing toxicity of anticancer chemotherapy

Country Status (21)

Country	Link
US (2)	US20030105104A1 (de)
EP (1)	EP1450781B1 (de)
JP (1)	JP4614660B2 (de)
KR (1)	KR100953483B1 (de)
CN (1)	CN100358527C (de)
AT (1)	ATE330595T1 (de)
BR (1)	BR0214430A (de)
CA (1)	CA2468133C (de)
DE (1)	DE60212693T2 (de)
EA (1)	EA009516B1 (de)
HU (1)	HU230986B1 (de)
IL (2)	IL162141A0 (de)
MX (1)	MXPA04004994A (de)
NO (1)	NO332858B1 (de)
NZ (1)	NZ532833A (de)
PL (1)	PL353656A1 (de)
RO (1)	RO121173B1 (de)
SI (1)	SI21542A (de)
UA (1)	UA78977C2 (de)
WO (1)	WO2003045372A1 (de)
ZA (1)	ZA200404115B (de)

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CA2839727C (en) *	2011-07-07	2023-10-17	Research Cancer Institute Of America	Systems, methods, and formulations for treating cancer
EP4417256A3 (de)	2013-03-11	2024-10-23	University of Florida Research Foundation, Inc.	Materialien und verfahren zur verbesserung der lungenfunktion
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2001
- 2001-11-27 US US09/995,010 patent/US20030105104A1/en not_active Abandoned
2002
- 2002-04-26 PL PL02353656A patent/PL353656A1/xx not_active Application Discontinuation
- 2002-11-21 CN CNB028236068A patent/CN100358527C/zh not_active Expired - Fee Related
- 2002-11-21 HU HU0402240A patent/HU230986B1/hu not_active IP Right Cessation
- 2002-11-21 NZ NZ532833A patent/NZ532833A/en not_active IP Right Cessation
- 2002-11-21 CA CA2468133A patent/CA2468133C/en not_active Expired - Fee Related
- 2002-11-21 KR KR1020047007754A patent/KR100953483B1/ko not_active Expired - Fee Related
- 2002-11-21 MX MXPA04004994A patent/MXPA04004994A/es active IP Right Grant
- 2002-11-21 SI SI200220037A patent/SI21542A/sl not_active IP Right Cessation
- 2002-11-21 UA UA20040605059A patent/UA78977C2/uk unknown
- 2002-11-21 BR BR0214430-1A patent/BR0214430A/pt not_active Application Discontinuation
- 2002-11-21 IL IL16214102A patent/IL162141A0/xx unknown
- 2002-11-21 WO PCT/US2002/037354 patent/WO2003045372A1/en not_active Ceased
- 2002-11-21 AT AT02789801T patent/ATE330595T1/de not_active IP Right Cessation
- 2002-11-21 RO ROA200400481A patent/RO121173B1/ro unknown
- 2002-11-21 JP JP2003546874A patent/JP4614660B2/ja not_active Expired - Fee Related
- 2002-11-21 EA EA200400737A patent/EA009516B1/ru not_active IP Right Cessation
- 2002-11-21 DE DE60212693T patent/DE60212693T2/de not_active Expired - Lifetime
- 2002-11-21 EP EP02789801A patent/EP1450781B1/de not_active Expired - Lifetime
2004
- 2004-05-24 IL IL162141A patent/IL162141A/en not_active IP Right Cessation
- 2004-05-26 ZA ZA2004/04115A patent/ZA200404115B/en unknown
- 2004-06-07 NO NO20042364A patent/NO332858B1/no not_active IP Right Cessation
2005
- 2005-04-18 US US11/108,277 patent/US7427619B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ZA200404115B (en)	2005-11-30
PL353656A1 (en)	2003-06-02
EP1450781B1 (de)	2006-06-21
CN100358527C (zh)	2008-01-02
KR20040065565A (ko)	2004-07-22
EA200400737A1 (ru)	2004-12-30
EA009516B1 (ru)	2008-02-28
IL162141A (en)	2009-05-04
NO332858B1 (no)	2013-01-21
RO121173B1 (ro)	2007-01-30
US20050182064A1 (en)	2005-08-18
NZ532833A (en)	2006-12-22
US20030105104A1 (en)	2003-06-05
KR100953483B1 (ko)	2010-04-16
HUP0402240A3 (en)	2012-09-28
BR0214430A (pt)	2004-11-03
HUP0402240A2 (hu)	2005-02-28
MXPA04004994A (es)	2005-04-08
WO2003045372A1 (en)	2003-06-05
NO20042364L (no)	2004-06-07
ATE330595T1 (de)	2006-07-15
AU2002352843A1 (en)	2003-06-10
DE60212693T2 (de)	2007-07-05
CA2468133C (en)	2011-02-22
JP4614660B2 (ja)	2011-01-19
CN1596109A (zh)	2005-03-16
DE60212693D1 (de)	2006-08-03
EP1450781A1 (de)	2004-09-01
SI21542A (sl)	2005-02-28
US7427619B2 (en)	2008-09-23
JP2005518361A (ja)	2005-06-23
IL162141A0 (en)	2005-11-20
HU230986B1 (hu)	2019-08-28
CA2468133A1 (en)	2003-06-05

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LLLGGGGG	0	LGGGGGGGGGS GGGGGGG LLLLLGLL GGGGL GGG LLLL
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JPS59501545A (ja)	1984-08-30	抗腫瘍医薬調剤
JP2011084536A (ja)	2011-04-28	経腸栄養剤