SI9200408A - Substituted 4(5)-amino-1,8-naphtyridine derivatives - Google Patents

Substituted 4(5)-amino-1,8-naphtyridine derivatives Download PDF

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Publication number
SI9200408A
SI9200408A SI19929200408A SI9200408A SI9200408A SI 9200408 A SI9200408 A SI 9200408A SI 19929200408 A SI19929200408 A SI 19929200408A SI 9200408 A SI9200408 A SI 9200408A SI 9200408 A SI9200408 A SI 9200408A
Authority
SI
Slovenia
Prior art keywords
group
hydrogen
alkyl group
formula
halo
Prior art date
Application number
SI19929200408A
Other languages
English (en)
Slovenian (sl)
Inventor
Bernard John Armitage
John Gareth Bowen
Malcolm John Crossley
Ian Michael Hunneyball
Bruce William Leslie
Thomas Kerr Miller
Michael Spowage
Original Assignee
The Boots Company Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Company Plc filed Critical The Boots Company Plc
Publication of SI9200408A publication Critical patent/SI9200408A/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI19929200408A 1991-12-23 1992-12-22 Substituted 4(5)-amino-1,8-naphtyridine derivatives SI9200408A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919127252A GB9127252D0 (en) 1991-12-23 1991-12-23 Therapeutic agents
CN93109454A CN1096784A (zh) 1991-12-23 1993-06-22 含取代4(5)-氨基-1,8-二氨杂萘的治疗剂

Publications (1)

Publication Number Publication Date
SI9200408A true SI9200408A (en) 1993-09-30

Family

ID=36822317

Family Applications (1)

Application Number Title Priority Date Filing Date
SI19929200408A SI9200408A (en) 1991-12-23 1992-12-22 Substituted 4(5)-amino-1,8-naphtyridine derivatives

Country Status (22)

Country Link
US (1) US5464781A (2)
EP (1) EP0618916B1 (2)
JP (1) JP2527917B2 (2)
CN (1) CN1096784A (2)
AT (1) ATE171452T1 (2)
AU (1) AU656832B2 (2)
BG (1) BG98813A (2)
CA (1) CA2125858A1 (2)
CZ (1) CZ153594A3 (2)
DE (1) DE69227125T2 (2)
FI (1) FI943019A7 (2)
GB (1) GB9127252D0 (2)
HR (1) HRP921455A2 (2)
HU (1) HUT66971A (2)
IL (1) IL104169A0 (2)
IN (1) IN174405B (2)
MX (1) MX9207494A (2)
NO (1) NO942376L (2)
NZ (1) NZ246156A (2)
SI (1) SI9200408A (2)
SK (1) SK75094A3 (2)
WO (1) WO1993013097A1 (2)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9312891D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
GB9318931D0 (en) * 1993-09-14 1993-10-27 Boots Co Plc Therapeutic agents
GB9420168D0 (en) * 1994-10-06 1994-11-23 Boots Co Plc Therapeutic agents
AR004010A1 (es) 1995-10-11 1998-09-30 Glaxo Group Ltd Compuestos heterociclicos
WO1998013350A1 (en) * 1996-09-25 1998-04-02 Zeneca Limited Qinoline derivatives inhibiting the effect of growth factors such as vegf
RS49779B (sr) 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
US6166069A (en) * 1998-05-12 2000-12-26 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
JP2003504363A (ja) 1999-07-09 2003-02-04 グラクソ グループ リミテッド プロテインチロシンキナーゼ阻害剤としてのアニリノキナゾリン類
US6933299B1 (en) 1999-07-09 2005-08-23 Smithkline Beecham Corporation Anilinoquinazolines as protein tyrosine kinase inhibitors
ES2267748T3 (es) 2000-04-07 2007-03-16 Astrazeneca Ab Compuestos de quinazolina.
US6534656B2 (en) * 2001-05-31 2003-03-18 North Carolina State University Short synthesis of pyridine-based pharmaceutical intermediates
JP2003329989A (ja) * 2002-03-06 2003-11-19 Nippon Telegr & Teleph Corp <Ntt> 光送信装置
GB0230018D0 (en) 2002-12-23 2003-01-29 Syngenta Ltd Fungicides
AU2004253967B2 (en) 2003-07-03 2010-02-18 Cytovia, Inc. 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
US8309562B2 (en) * 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
WO2006074147A2 (en) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
AU2004309166B2 (en) 2003-12-23 2008-02-21 Pfizer Inc. Novel quinoline derivatives
US8258145B2 (en) * 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
EP2345652A1 (en) 2005-12-21 2011-07-20 Abbott Laboratories Antiviral compounds
US7910595B2 (en) * 2005-12-21 2011-03-22 Abbott Laboratories Anti-viral compounds
EP1979349B1 (en) * 2005-12-21 2010-07-28 Abbott Laboratories Anti-viral compounds
TWI392676B (zh) * 2005-12-21 2013-04-11 Abbott Lab 抗病毒化合物、其製備方法及用途
WO2007081517A2 (en) 2005-12-21 2007-07-19 Abbott Laboratories Anti-viral compounds
US8236950B2 (en) 2006-12-20 2012-08-07 Abbott Laboratories Anti-viral compounds
MX2010013842A (es) * 2008-07-03 2011-01-14 Merck Patent Gmbh Naftiridinonas como inhibidores de aurora cinasa.
WO2010097410A1 (en) 2009-02-24 2010-09-02 Respiratorius Ab Novel bronchodilating diazaheteroaryls
US8853235B2 (en) * 2009-11-23 2014-10-07 Senhwa Biosciences, Inc. Polymorphs and salts of a kinase inhibitor
RU2605549C2 (ru) 2010-04-02 2016-12-20 Синомикс, Инк. Производные 3-карбокси-4-аминохинолина, полезные как модификаторы сладкого вкуса

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466965A (en) * 1982-07-26 1984-08-21 American Hospital Supply Corporation Phthalazine compounds, compositions and use
NZ213986A (en) * 1984-10-30 1989-07-27 Usv Pharma Corp Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such
EP0222839A4 (en) * 1985-05-17 1988-11-09 Univ Australian ANTI-MALARIA COMPOUNDS.
JPS6368568A (ja) * 1986-09-10 1988-03-28 Otsuka Pharmaceut Factory Inc ｐ−アミノフエノ−ル誘導体
DE3644825A1 (de) * 1986-12-31 1988-07-14 Basf Ag Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide
WO1989000571A2 (en) * 1987-07-22 1989-01-26 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US4978661A (en) * 1988-09-29 1990-12-18 Innocenzo Caruso Use of 6-halo-4-quinolone compounds and pharmaceutical compositions thereof for the preparation of a medicament for the therapeutical application in rheumatoid arthritis
GR900100380A (el) * 1989-05-20 1991-10-10 Fisons Plc Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives
JP2988739B2 (ja) * 1990-04-16 1999-12-13 協和醗酵工業株式会社 １，８−ナフチリジン−２−オン誘導体
JP3157077B2 (ja) * 1994-02-16 2001-04-16 内山工業株式会社 ベアリングシール

Also Published As

Publication number Publication date
AU3158793A (en) 1993-07-28
US5464781A (en) 1995-11-07
IL104169A0 (en) 1993-05-13
JPH07502280A (ja) 1995-03-09
NO942376D0 (2) 1994-06-22
JP2527917B2 (ja) 1996-08-28
BG98813A (bg) 1995-05-31
ATE171452T1 (de) 1998-10-15
FI943019A0 (fi) 1994-06-22
DE69227125T2 (de) 1999-02-18
EP0618916B1 (en) 1998-09-23
HRP921455A2 (en) 1994-12-31
CZ153594A3 (en) 1995-02-15
FI943019A7 (fi) 1994-06-22
HU9401877D0 (en) 1994-09-28
HUT66971A (en) 1995-01-30
IN174405B (2) 1994-11-26
NO942376L (no) 1994-06-22
SK75094A3 (en) 1995-04-12
WO1993013097A1 (en) 1993-07-08
AU656832B2 (en) 1995-02-16
DE69227125D1 (de) 1998-10-29
CA2125858A1 (en) 1993-07-08
NZ246156A (en) 1996-01-26
CN1096784A (zh) 1994-12-28
MX9207494A (es) 1993-07-01
EP0618916A1 (en) 1994-10-12
GB9127252D0 (en) 1992-02-19

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