SK13896A3 - Substituted derivatives of indole, method of their manufacture, their use and medicaments containing these compounds - Google Patents

Substituted derivatives of indole, method of their manufacture, their use and medicaments containing these compounds Download PDF

Info

Publication number
SK13896A3
SK13896A3 SK138-96A SK13896A SK13896A3 SK 13896 A3 SK13896 A3 SK 13896A3 SK 13896 A SK13896 A SK 13896A SK 13896 A3 SK13896 A3 SK 13896A3
Authority
SK
Slovakia
Prior art keywords
group
carbon atoms
straight
substituted indole
indole derivatives
Prior art date
Application number
SK138-96A
Other languages
English (en)
Slovak (sk)
Inventor
Matthias Muller-Gliemann
Ulrich Muller
Martin Beuck
Siegfried Zaiss
Christoph Gerdes
Anke Domdey-Bette
Rudi Grutzmann
Stefan Lohmer
Stefan Wohlfeil
Ozkan Yalkinoglu
James Elting
Dirk Denzer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19513716A external-priority patent/DE19513716A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SK13896A3 publication Critical patent/SK13896A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
SK138-96A 1995-02-01 1996-01-31 Substituted derivatives of indole, method of their manufacture, their use and medicaments containing these compounds SK13896A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19503159 1995-02-01
DE19513716A DE19513716A1 (de) 1995-02-01 1995-04-11 Substituierte 2-Phenylindol-Derivate

Publications (1)

Publication Number Publication Date
SK13896A3 true SK13896A3 (en) 1996-10-02

Family

ID=26012026

Family Applications (1)

Application Number Title Priority Date Filing Date
SK138-96A SK13896A3 (en) 1995-02-01 1996-01-31 Substituted derivatives of indole, method of their manufacture, their use and medicaments containing these compounds

Country Status (25)

Country Link
US (1) US5607962A (es)
EP (1) EP0725061B1 (es)
JP (1) JPH08253451A (es)
CN (1) CN1067987C (es)
AR (1) AR002271A1 (es)
AT (1) ATE193701T1 (es)
AU (1) AU708784B2 (es)
BG (1) BG62807B1 (es)
CA (1) CA2168320A1 (es)
CZ (1) CZ28996A3 (es)
DK (1) DK0725061T3 (es)
DZ (1) DZ1985A1 (es)
EE (1) EE9600021A (es)
ES (1) ES2148600T3 (es)
FI (1) FI960424L (es)
GR (1) GR3034245T3 (es)
HR (1) HRP960015B1 (es)
HU (1) HUP9600231A2 (es)
IL (1) IL116956A (es)
MA (1) MA23795A1 (es)
NO (1) NO305119B1 (es)
NZ (1) NZ280906A (es)
PL (1) PL312545A1 (es)
PT (1) PT725061E (es)
SK (1) SK13896A3 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525028A1 (de) * 1995-07-10 1997-01-16 Bayer Ag Amide und Sulfonamide von heterocyclisch substituierten Benzylaminen
DE19924818A1 (de) 1999-05-29 2000-11-30 Bayer Ag Substituierte Phenylcyclohexancarbonsäureamide
DE10044792A1 (de) * 2000-09-11 2002-04-04 Bayer Ag Substituierte Phenylcyclohexancarbonsäureamide und ihre Verwendung
GB0208642D0 (en) 2002-04-16 2002-05-22 Accentus Plc Metal implants
GB0405680D0 (en) 2004-03-13 2004-04-21 Accentus Plc Metal implants
ES2573290T3 (es) 2007-10-03 2016-06-07 Accentus Medical Limited Método de fabricación de metal con propiedades biocidas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908367A (en) * 1985-07-11 1990-03-13 Roussel Uclaf N-(1H-indole-4-yl)-benzamides
JPH07103105B2 (ja) * 1989-05-12 1995-11-08 杏林製薬株式会社 インドール誘導体及びその製造方法
DE4221009A1 (de) * 1992-06-26 1994-01-05 Bayer Ag Imidazolyl-substituierte Cyclohexanderivate
DE4304455A1 (de) * 1993-02-15 1994-08-18 Bayer Ag Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate
US5358959A (en) * 1993-02-18 1994-10-25 President And Fellows Of Harvard University Methods for treating arteriosclerosis
DE4308788A1 (de) * 1993-03-18 1994-09-22 Bayer Ag Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate
DE4401893A1 (de) * 1994-01-24 1995-07-27 Bayer Ag Substituierte Arylharnstoffe

Also Published As

Publication number Publication date
NO960413D0 (no) 1996-01-31
BG62807B1 (bg) 2000-08-31
US5607962A (en) 1997-03-04
EE9600021A (et) 1996-08-15
CA2168320A1 (en) 1996-08-02
AU708784B2 (en) 1999-08-12
DZ1985A1 (fr) 2002-10-15
MA23795A1 (fr) 1996-10-01
NZ280906A (en) 1996-10-28
HU9600231D0 (en) 1996-03-28
NO960413L (no) 1996-08-02
PT725061E (pt) 2000-11-30
AR002271A1 (es) 1998-03-11
ATE193701T1 (de) 2000-06-15
CZ28996A3 (en) 1996-08-14
JPH08253451A (ja) 1996-10-01
GR3034245T3 (en) 2000-12-29
EP0725061A1 (de) 1996-08-07
IL116956A0 (en) 1996-05-14
FI960424A0 (fi) 1996-01-30
HRP960015B1 (en) 2000-12-31
FI960424A7 (fi) 1996-08-02
NO305119B1 (no) 1999-04-06
HUP9600231A3 (en) 1997-05-28
ES2148600T3 (es) 2000-10-16
CN1137520A (zh) 1996-12-11
DK0725061T3 (da) 2000-10-02
EP0725061B1 (de) 2000-06-07
PL312545A1 (en) 1996-08-05
AU4224196A (en) 1996-08-08
BG100325A (bg) 1996-08-30
CN1067987C (zh) 2001-07-04
HRP960015A2 (en) 1997-10-31
HUP9600231A2 (en) 1997-05-28
FI960424L (fi) 1996-08-02
IL116956A (en) 2000-02-17

Similar Documents

Publication Publication Date Title
JP4316794B2 (ja) イソキノリン誘導体及び医薬
JP2005535702A (ja) 新規化合物
JPH09208545A (ja) アルコールまたはアルデヒド誘導体およびその用途
CN103781753B (zh) 用于治疗ape1介导的疾病的醌化合物
CZ286739B6 (en) Imidazopyridine derivative, process of its preparation and pharmaceutical preparation containing thereof
US10456405B2 (en) Nitric oxide-releasing prodrug molecule of substituted quinazolines
KR20140117356A (ko) N-포밀 펩타이드 수용체 유사-1(fprl-1) 수용체 조절제로서의 아릴 유레아 유도체
FI112660B (fi) Menetelmä matriksin metalloproteaasien inhibiittoreina käyttökelpoisten trisyklisten indolijohdannaisten valmistamiseksi
WO2007017092A1 (en) Substituted 4-benzyloxy-benzoic acid amide derivatives
AU710235B2 (en) Use of phenylcyclohexylcarboxamides
CZ28996A3 (en) Substituted indole derivatives, process of their preparation, their use and medicaments in which said compound are comprised
SK32194A3 (en) Hetero-tricyclic substituted derivatives of phenyl- -cyclohexanecarboxyle acid, method of their production treatments containing these matters, method of their production and using of this matters
CZ51693A3 (en) Propenoyl-imidazole derivatives
SK35094A3 (en) Phenylglycinamides heterocyclic substituted derivatives of phenylacetic acid, method of their production, medicines contains these matters, method of their production and using of these matters
CA3149128A1 (en) Composition and methods for the treatment of anal and rectal disorders
RU2162842C2 (ru) Производные 2-фенилиндола, смесь их изомеров, или отдельные изомеры, или их физиологически приемлемые соли, фармацевтическая композиция, проявляющая антипролиферативную активность
GB2344821A (en) Crystalline pharmaceutically acceptable salt of an oxazolidinone derivative
US20010051637A1 (en) Indole derivatives as prodrugs of 5-HT1-like receptor agonists
CS209950B2 (en) Method of making the new 4- amino-6,7-dialcoxy-2-piperazinochinazoline derivatives