SK18292000A3 - Močoviny a karbamáty n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie - Google Patents

Močoviny a karbamáty n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie Download PDF

Info

Publication number: SK18292000A3
Authority: SK; Slovakia
Prior art keywords: carboxylic acid; hydrogen; straight; branched chain; substituted
Prior art date: 1998-06-03

Application number

SK1829-2000A

Other languages

English (en)

Slovak (sk)

Inventor

Gregory S. Hamilton

Mark H. Norman

Yong-Qian Wu

Original Assignee

Gpi Nil Holdings, Inc.

Amgen Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-03

Filing date

1998-12-03

Publication date

2001-07-10

1998-12-03 Application filed by Gpi Nil Holdings, Inc., Amgen Inc. filed Critical Gpi Nil Holdings, Inc.

2001-07-10 Publication of SK18292000A3 publication Critical patent/SK18292000A3/sk

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Birds (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Dermatology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

SK1829-2000A 1998-06-03 1998-12-03 Močoviny a karbamáty n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie SK18292000A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8784498P	1998-06-03	1998-06-03
PCT/US1998/025570 WO1999062879A1 (en)	1998-06-03	1998-12-03	Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres

Publications (1)

Publication Number	Publication Date
SK18292000A3 true SK18292000A3 (sk)	2001-07-10

Family

ID=22207585

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1829-2000A SK18292000A3 (sk)	1998-06-03	1998-12-03	Močoviny a karbamáty n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie

Country Status (17)

Country	Link
US (2)	US20020007075A1 (no)
EP (1)	EP1082301A1 (no)
JP (1)	JP2002516903A (no)
KR (1)	KR20010052502A (no)
CN (1)	CN1299346A (no)
AU (1)	AU1620499A (no)
BG (1)	BG105014A (no)
BR (1)	BR9815881A (no)
CA (1)	CA2333960A1 (no)
EA (1)	EA200001246A1 (no)
HU (1)	HUP0102847A2 (no)
IL (1)	IL140039A0 (no)
NO (1)	NO20006111L (no)
PL (1)	PL348671A1 (no)
SK (1)	SK18292000A3 (no)
WO (1)	WO1999062879A1 (no)
ZA (1)	ZA9811061B (no)

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* Cited by examiner, † Cited by third party
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JP2000302757A (ja) *	1999-04-16	2000-10-31	Shiseido Co Ltd	Ｎ−置換ピペリジン誘導体
US6809107B1 (en) *	1999-07-09	2004-10-26	Ortho-Mcneil Pharmaceutical, Inc.	Neurotrophic pyrrolidines and piperidines, and related compositions and methods
CN100400040C (zh) *	2000-10-30	2008-07-09	詹森药业有限公司	三肽酶抑制剂
EP2661433B1 (en)	2011-01-04	2017-08-16	Novartis AG	Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd)
JP6214647B2 (ja)	2012-06-28	2017-10-18	ノバルティスアーゲー	補体経路モジュレーターおよびその使用
JP6273274B2 (ja)	2012-06-28	2018-01-31	ノバルティスアーゲー	補体経路モジュレーターおよびその使用
CN104379579B (zh)	2012-06-28	2017-03-08	诺华股份有限公司	吡咯烷衍生物及其作为补体途径调节剂的用途
ES2644700T3 (es)	2012-06-28	2017-11-30	Novartis Ag	Derivados de pirrolidina y su uso como moduladores de la ruta del complemento
WO2014002054A1 (en)	2012-06-28	2014-01-03	Novartis Ag	Pyrrolidine derivatives and their use as complement pathway modulators
WO2014009833A2 (en)	2012-07-12	2014-01-16	Novartis Ag	Complement pathway modulators and uses thereof
WO2023090853A1 (ko) *	2021-11-19	2023-05-25	고려대학교 세종산학협력단	신규 우레아계 또는 카바메이트계 p2x7 수용체 길항제 및 이를 유효성분으로 포함하는 주요 우울 장애의 예방 또는 치료용 약학 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55151555A (en) *	1979-05-14	1980-11-26	Tanabe Seiyaku Co Ltd	Proline derivatives and their production
US4402969A (en) *	1981-03-23	1983-09-06	Merck & Co., Inc.	Antihypertensive proline derivatives
DE3134933A1 (de) *	1981-09-03	1983-03-31	Hoechst Ag, 6230 Frankfurt	"harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung"
JPS58170752A (ja) *	1982-03-30	1983-10-07	Kureha Chem Ind Co Ltd	Ｎ−カルバモイルアミノ酸誘導体
DE4228455A1 (de) *	1992-08-26	1994-09-15	Beiersdorf Ag	Kosmetische und dermatologische Lichtschutzformulierungen mit einem Gehalt an Thiolen und/oder Thiolderivaten
US5411991A (en) *	1992-12-22	1995-05-02	Shander; Douglas	Method of reducing hair growth employing sulfhydryl active compounds
US5264619B1 (en) *	1993-01-15	1996-05-14	Cosmos Pharm Corp	Anti-androgenic cyclo and bicyclo alkenes
US5744485A (en) *	1994-03-25	1998-04-28	Vertex Pharmaceuticals Incorporated	Carbamates and ureas as modifiers of multi-drug resistance
US5780484A (en) *	1996-11-13	1998-07-14	Vertex Pharmaceuticals Incorporated	Methods for stimulating neurite growth with piperidine compounds
US5935989A (en) *	1996-12-31	1999-08-10	Gpi Nil Holdings Inc.	N-linked ureas and carbamates of heterocyclic thioesters

1998
- 1998-12-03 PL PL98348671A patent/PL348671A1/xx unknown
- 1998-12-03 IL IL14003998A patent/IL140039A0/xx unknown
- 1998-12-03 EP EP98960656A patent/EP1082301A1/en not_active Withdrawn
- 1998-12-03 JP JP2000552091A patent/JP2002516903A/ja active Pending
- 1998-12-03 AU AU16204/99A patent/AU1620499A/en not_active Abandoned
- 1998-12-03 CA CA002333960A patent/CA2333960A1/en not_active Abandoned
- 1998-12-03 WO PCT/US1998/025570 patent/WO1999062879A1/en not_active Ceased
- 1998-12-03 BR BR9815881-3A patent/BR9815881A/pt not_active Application Discontinuation
- 1998-12-03 KR KR1020007013636A patent/KR20010052502A/ko not_active Withdrawn
- 1998-12-03 SK SK1829-2000A patent/SK18292000A3/sk unknown
- 1998-12-03 CN CN98814098A patent/CN1299346A/zh active Pending
- 1998-12-03 EA EA200001246A patent/EA200001246A1/ru unknown
- 1998-12-03 HU HU0102847A patent/HUP0102847A2/hu unknown
- 1998-12-03 ZA ZA9811061A patent/ZA9811061B/xx unknown
2000
- 2000-12-01 BG BG105014A patent/BG105014A/xx unknown
- 2000-12-01 NO NO20006111A patent/NO20006111L/no not_active Application Discontinuation
2001
- 2001-01-30 US US09/771,686 patent/US20020007075A1/en not_active Abandoned
- 2001-05-03 US US09/847,432 patent/US20020042442A1/en not_active Abandoned

Also Published As

Publication number	Publication date
KR20010052502A (ko)	2001-06-25
EA200001246A1 (ru)	2001-08-27
PL348671A1 (en)	2002-06-03
AU1620499A (en)	1999-12-20
BG105014A (en)	2001-08-31
IL140039A0 (en)	2002-02-10
CA2333960A1 (en)	1999-12-09
JP2002516903A (ja)	2002-06-11
US20020007075A1 (en)	2002-01-17
NO20006111L (no)	2001-02-01
ZA9811061B (en)	1999-12-03
WO1999062879A1 (en)	1999-12-09
US20020042442A1 (en)	2002-04-11
EP1082301A1 (en)	2001-03-14
CN1299346A (zh)	2001-06-13
HUP0102847A2 (hu)	2001-12-28
WO1999062879A8 (en)	2000-05-04
BR9815881A (pt)	2002-07-23
NO20006111D0 (no)	2000-12-01

Publication	Publication Date	Title
US7459473B2 (en)	2008-12-02	N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres
EP1084107B1 (en)	2007-04-11	Aza-heterocyclic compounds used to treat neurological disorders and hair loss
SK18292000A3 (sk)	2001-07-10	Močoviny a karbamáty n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
US20020045641A1 (en)	2002-04-18	Multiple heteroatom containing heterocyclic ring compounds substituted with carboxylic acids and isosteres thereof
EP1842845B1 (en)	2014-07-16	Aza-heterocyclic compounds used to treat neurological disorders and hair loss
CN101245043B (zh)	2013-02-13	N-杂环化合物的羧酸和羧酸电子等排物
AU2004200797B2 (en)	2008-04-10	Carboxylic Acids and Carboxylic Acid Isosteres of N-Heterocyclic Compounds
HK1109893A (en)	2008-06-27	Aza-heterocyclic compounds used to treat neurological disorders and hair loss
MXPA00011906A (en)	2002-07-25	Aza-heterocyclic compounds used to treat neurological disorders and hair loss
MXPA00011808A (en)	2002-07-25	N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres
MXPA00011811A (en)	2002-07-25	Ureas and carbamates of n-heterocyclic carboxylic acids and carboxylic acid isosteres
MXPA00011843A (en)	2001-09-07	Aza-heterocyclic compounds used to treat neurological disorders and hair loss
CZ20004470A3 (cs)	2001-05-16	Aza-heterocyklické sloučeniny používané k léčbě neurologických poruch a ztráty vlasů
CZ20004473A3 (cs)	2001-03-14	Močoviny a karbamáty N-heterocyklických karboxylových kyselin a isosterů karboxylových kyselin
CZ20004472A3 (cs)	2001-03-14	N-sulfonamidy N-heterocyklických karboxylových kyselin nebo isosterů karboxylových kyselin
CZ20004471A3 (cs)	2001-04-11	AZA-heterocyklické sloučeniny používané k léčbě neurologických poruch a ztráty vlasů