SK287357B6 - Použitie antagonistu alfa v beta 3 na prípravu farmaceutickej kompozície na liečbu tumorových buniek a terapeutická kompozícia a súprava na liečenie tumoru alebo tumorových metastáz - Google Patents

Použitie antagonistu alfa v beta 3 na prípravu farmaceutickej kompozície na liečbu tumorových buniek a terapeutická kompozícia a súprava na liečenie tumoru alebo tumorových metastáz Download PDF

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Publication number
SK287357B6
SK287357B6 SK1113-2001A SK11132001A SK287357B6 SK 287357 B6 SK287357 B6 SK 287357B6 SK 11132001 A SK11132001 A SK 11132001A SK 287357 B6 SK287357 B6 SK 287357B6
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SK
Slovakia
Prior art keywords
tumor
antigen
antitumor
angiogenesis
kit
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SK1113-2001A
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English (en)
Slovak (sk)
Other versions
SK11132001A3 (sk
Inventor
Holger N. Lode
Ralph A. Reisfeld
David A. Cheresh
Stephen D. Gillies
Original Assignee
The Scripps Research Institute
Lexigen Pharmaceuticals Corporation
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Publication date
Application filed by The Scripps Research Institute, Lexigen Pharmaceuticals Corporation filed Critical The Scripps Research Institute
Publication of SK11132001A3 publication Critical patent/SK11132001A3/sk
Publication of SK287357B6 publication Critical patent/SK287357B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
SK1113-2001A 1999-02-12 2000-02-11 Použitie antagonistu alfa v beta 3 na prípravu farmaceutickej kompozície na liečbu tumorových buniek a terapeutická kompozícia a súprava na liečenie tumoru alebo tumorových metastáz SK287357B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11972199P 1999-02-12 1999-02-12
PCT/US2000/003483 WO2000047228A1 (fr) 1999-02-12 2000-02-11 Methodes de traitement des tumeurs et des metastases au moyen d'une combinaison de therapies anti-angiogeniques et d'immunotherapies

Publications (2)

Publication Number Publication Date
SK11132001A3 SK11132001A3 (sk) 2002-06-04
SK287357B6 true SK287357B6 (sk) 2010-08-09

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SK1113-2001A SK287357B6 (sk) 1999-02-12 2000-02-11 Použitie antagonistu alfa v beta 3 na prípravu farmaceutickej kompozície na liečbu tumorových buniek a terapeutická kompozícia a súprava na liečenie tumoru alebo tumorových metastáz

Country Status (22)

Country Link
US (3) US7115261B1 (fr)
EP (1) EP1156823B1 (fr)
JP (2) JP4841727B2 (fr)
KR (1) KR100704140B1 (fr)
CN (1) CN1192796C (fr)
AT (1) ATE412433T1 (fr)
AU (1) AU776790B2 (fr)
BR (1) BR0008161A (fr)
CA (1) CA2360106C (fr)
CZ (1) CZ303155B6 (fr)
DE (1) DE60040651D1 (fr)
DK (1) DK1156823T3 (fr)
ES (1) ES2313883T3 (fr)
HU (1) HU229520B1 (fr)
MX (1) MXPA01008110A (fr)
NO (2) NO331072B1 (fr)
PL (1) PL200919B1 (fr)
PT (1) PT1156823E (fr)
RU (1) RU2236251C2 (fr)
SI (1) SI1156823T1 (fr)
SK (1) SK287357B6 (fr)
WO (1) WO2000047228A1 (fr)

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HU229520B1 (en) 2014-01-28
EP1156823B1 (fr) 2008-10-29
SI1156823T1 (sl) 2009-02-28
NO20101696L (no) 2001-10-09
JP4841727B2 (ja) 2011-12-21
EP1156823A1 (fr) 2001-11-28
NO331072B1 (no) 2011-09-26
BR0008161A (pt) 2002-05-28
NO20013906D0 (no) 2001-08-10
US7365054B2 (en) 2008-04-29
US7833976B2 (en) 2010-11-16
PT1156823E (pt) 2009-01-08
JP2002536419A (ja) 2002-10-29
US7115261B1 (en) 2006-10-03
SK11132001A3 (sk) 2002-06-04
CZ20012791A3 (cs) 2002-05-15
AU776790B2 (en) 2004-09-23
ES2313883T3 (es) 2009-03-16
MXPA01008110A (es) 2002-10-23
US20070036751A1 (en) 2007-02-15
ATE412433T1 (de) 2008-11-15
US20090060864A1 (en) 2009-03-05
CN1192796C (zh) 2005-03-16
CA2360106C (fr) 2012-10-30
RU2236251C2 (ru) 2004-09-20
PL350329A1 (en) 2002-12-02
DE60040651D1 (de) 2008-12-11
EP1156823A4 (fr) 2003-02-19
DK1156823T3 (da) 2009-01-19
WO2000047228A1 (fr) 2000-08-17
PL200919B1 (pl) 2009-02-27
KR20010102043A (ko) 2001-11-15
CZ303155B6 (cs) 2012-05-09
NO20013906L (no) 2001-10-09
CA2360106A1 (fr) 2000-08-17
CN1346279A (zh) 2002-04-24
JP2011207892A (ja) 2011-10-20
AU3228000A (en) 2000-08-29
KR100704140B1 (ko) 2007-04-09
HUP0200128A2 (en) 2002-05-29

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