SK287992B6 - Combination of fenofibrate and coenzyme Q10 for the treatment of endothelial dysfunction - Google Patents

Combination of fenofibrate and coenzyme Q10 for the treatment of endothelial dysfunction Download PDF

Info

Publication number: SK287992B6
Authority: SK; Slovakia
Prior art keywords: ubiquinone; ppar; activator; fenofibrate; composition
Prior art date: 2000-10-26

Application number

SK508-2003A

Other languages

English (en)

Slovak (sk)

Other versions

SK5082003A3 (en

Inventor

Gerald Watts

David Playford

Original Assignee

Fournier Laboratories Ireland Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-26

Filing date

2001-10-23

Publication date

2012-09-03

2000-10-26 Priority claimed from AUPR1038A external-priority patent/AUPR103800A0/en

2001-02-28 Priority claimed from AUPR3424A external-priority patent/AUPR342401A0/en

2001-10-23 Application filed by Fournier Laboratories Ireland Limited filed Critical Fournier Laboratories Ireland Limited

2003-11-04 Publication of SK5082003A3 publication Critical patent/SK5082003A3/sk

2012-09-03 Publication of SK287992B6 publication Critical patent/SK287992B6/sk

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Classifications

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- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SK508-2003A 2000-10-26 2001-10-23 Combination of fenofibrate and coenzyme Q10 for the treatment of endothelial dysfunction SK287992B6 (sk)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AUPR1038A AUPR103800A0 (en)	2000-10-26	2000-10-26	Compositions for the treatment of endothelial dysfunction
AUPR3424A AUPR342401A0 (en)	2001-02-28	2001-02-28	Compositions for the treatment of endothelial dysfunction
PCT/EP2001/012425 WO2002034259A1 (fr)	2000-10-26	2001-10-23	Combinaison de fenofibrate et de coenzyme q10 permettant de traiter un dysfonctionnement endothelial

Publications (2)

Publication Number	Publication Date
SK5082003A3 SK5082003A3 (en)	2003-11-04
SK287992B6 true SK287992B6 (sk)	2012-09-03

Family

ID=25646491

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK508-2003A SK287992B6 (sk)	2000-10-26	2001-10-23	Combination of fenofibrate and coenzyme Q10 for the treatment of endothelial dysfunction

Country Status (29)

Country	Link
US (1)	US7410983B2 (fr)
EP (1)	EP1328266B1 (fr)
JP (1)	JP4236464B2 (fr)
KR (1)	KR100862129B1 (fr)
CN (1)	CN1220488C (fr)
AR (1)	AR035071A1 (fr)
AT (1)	ATE316787T1 (fr)
AU (1)	AU2176502A (fr)
BG (1)	BG65979B1 (fr)
BR (1)	BR0114701A (fr)
CA (1)	CA2426625C (fr)
CY (1)	CY1105007T1 (fr)
CZ (1)	CZ301282B6 (fr)
DE (1)	DE60117046T2 (fr)
DK (1)	DK1328266T3 (fr)
DZ (1)	DZ3442A1 (fr)
EE (1)	EE05281B1 (fr)
ES (1)	ES2257457T3 (fr)
HU (1)	HUP0303566A3 (fr)
IL (2)	IL155524A0 (fr)
MA (1)	MA25847A1 (fr)
MX (1)	MXPA03003733A (fr)
NO (1)	NO332260B1 (fr)
PL (1)	PL212952B1 (fr)
PT (1)	PT1328266E (fr)
RU (1)	RU2003111175A (fr)
SK (1)	SK287992B6 (fr)
TN (1)	TNSN01151A1 (fr)
WO (1)	WO2002034259A1 (fr)

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FR2845602B1 (fr) *	2002-10-11	2005-07-08	Servier Lab	Association entre un ligand des recepteurs actives par les proliferateurs de peroxisomes et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
GB0309154D0 (en)	2003-01-14	2003-05-28	Aventis Pharma Inc	Use of insulin glargine to reduce or prevent cardiovascular events in patients being treated for dysglycemia
JP2005104951A (ja) *	2003-01-17	2005-04-21	Kirin Brewery Co Ltd	血圧降下用組成物および血管柔軟性改善用組成物並びにこれらの機能が付与された食品
FR2868313B1 (fr) *	2004-03-31	2008-08-15	Servier Lab	Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
EP1621200A1 (fr) *	2004-07-26	2006-02-01	Fournier Laboratories Ireland Limited	Combinaison pharmaceutique comprenant un inhibiteur de l'aggregation des thrombocytes et un fibrate
CA2610152C (fr)	2005-06-01	2018-04-10	Edison Pharmaceuticals, Inc.	Medicaments pouvant subir une oxydo-reduction destines au traitement des maladies mitochondriales et d'autres affections et modulation de biomarqueurs relatifs a l'etat energetique
ES2823728T3 (es)	2005-09-15	2021-05-10	Ptc Therapeutics Inc	Variantes de cola de agentes terapéuticos con actividad redox para el tratamiento de enfermedades mitocondriales y otras afecciones y la modulación de biomarcadores de energía
EP1785133A1 (fr) *	2005-11-10	2007-05-16	Laboratoires Fournier S.A.	Utilisation du fenofibrate ou d'un de ses dérivés pour la prevention de la retinopathie diabetique
EA019675B1 (ru)	2006-02-22	2014-05-30	Эдисон Фармасьютикалз, Инк.	Редокс-активные терапевтические средства для лечения митохондриальных заболеваний и модуляции биомаркера коэнзима q
WO2007106912A2 (fr) *	2006-03-16	2007-09-20	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Agonistes du récepteur-alpha activé de la prolifération des peroxysomes pour la conservation d'organe
US20070225606A1 (en) *	2006-03-22	2007-09-27	Endothelix, Inc.	Method and apparatus for comprehensive assessment of vascular health
US20080027330A1 (en) *	2006-05-15	2008-01-31	Endothelix, Inc.	Risk assessment method for acute cardiovascular events
US20080081963A1 (en) *	2006-09-29	2008-04-03	Endothelix, Inc.	Methods and Apparatus for Profiling Cardiovascular Vulnerability to Mental Stress
KR100989093B1 (ko)	2008-01-18	2010-10-25	한화제약주식회사	생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물
BRPI0918139B1 (pt)	2008-09-10	2024-04-30	Ptc Therapeutics, Inc	Composição, alimento medicinal ou funcional, suplemento alimentar ou dietético para tratamento de distúrbios de desenvolvimento pervasivos com terapêuticos redox-ativos
WO2010088378A1 (fr) *	2009-01-29	2010-08-05	Levine Joshua D	Procédé d'ajout d'agents botaniques/de suppléments de régime à des agents pharmaceutiques dans un régime pharmacothérapeutique
US8973851B2 (en) *	2009-07-01	2015-03-10	The Procter & Gamble Company	Apparatus and methods for producing charged fluid droplets
ES2657940T3 (es) *	2010-03-26	2018-03-07	Emerald Health Pharmaceuticals Inc.	Derivados de quinona de cannabinoides
RU2554500C2 (ru) *	2013-09-20	2015-06-27	Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ)	Способ лечения ишемического инсульта
CN113024369A (zh)	2015-12-17	2021-06-25	Ptc医疗公司	用于治疗氧化应急障碍的化合物
US10881686B2 (en)	2017-10-27	2021-01-05	Zeta Biolongevity, Inc	Compositions and methods for treating and preventing proteinuria and endothelial erosion
CN110907407B (zh) *	2019-12-03	2022-02-25	东北石油大学	一种基于spr的高灵敏度光子准晶体光纤折射率传感器

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FR2627696B1 (fr)	1988-02-26	1991-09-13	Fournier Innovation Synergie	Nouvelle forme galenique du fenofibrate
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2001
- 2001-10-23 MX MXPA03003733A patent/MXPA03003733A/es active IP Right Grant
- 2001-10-23 EP EP01988586A patent/EP1328266B1/fr not_active Expired - Lifetime
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- 2001-10-23 RU RU2003111175/15A patent/RU2003111175A/ru not_active Application Discontinuation
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- 2001-10-23 DZ DZ013442A patent/DZ3442A1/fr active
- 2001-10-23 EE EEP200300165A patent/EE05281B1/xx not_active IP Right Cessation
- 2001-10-23 HU HU0303566A patent/HUP0303566A3/hu unknown
- 2001-10-23 US US10/399,639 patent/US7410983B2/en not_active Expired - Fee Related
- 2001-10-23 DK DK01988586T patent/DK1328266T3/da active
- 2001-10-23 CA CA2426625A patent/CA2426625C/fr not_active Expired - Fee Related
- 2001-10-23 AT AT01988586T patent/ATE316787T1/de active
- 2001-10-23 SK SK508-2003A patent/SK287992B6/sk unknown
- 2001-10-23 IL IL15552401A patent/IL155524A0/xx active IP Right Grant
- 2001-10-23 JP JP2002537311A patent/JP4236464B2/ja not_active Expired - Fee Related
- 2001-10-23 CZ CZ20031148A patent/CZ301282B6/cs not_active IP Right Cessation
- 2001-10-23 PL PL361635A patent/PL212952B1/pl not_active IP Right Cessation
- 2001-10-23 DE DE60117046T patent/DE60117046T2/de not_active Expired - Lifetime
- 2001-10-23 BR BR0114701-3A patent/BR0114701A/pt not_active Application Discontinuation
- 2001-10-23 WO PCT/EP2001/012425 patent/WO2002034259A1/fr not_active Ceased
- 2001-10-23 PT PT01988586T patent/PT1328266E/pt unknown
- 2001-10-23 ES ES01988586T patent/ES2257457T3/es not_active Expired - Lifetime
- 2001-10-23 KR KR1020037004793A patent/KR100862129B1/ko not_active Expired - Fee Related
- 2001-10-25 TN TNTNSN01151A patent/TNSN01151A1/en unknown
- 2001-10-26 AR ARP010105032A patent/AR035071A1/es unknown
2003
- 2003-04-21 IL IL155524A patent/IL155524A/en not_active IP Right Cessation
- 2003-04-24 NO NO20031851A patent/NO332260B1/no not_active IP Right Cessation
- 2003-04-25 BG BG107765A patent/BG65979B1/bg unknown
- 2003-04-25 MA MA27124A patent/MA25847A1/fr unknown
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Also Published As

Publication number	Publication date
CY1105007T1 (el)	2009-11-04
BR0114701A (pt)	2003-11-18
PL212952B1 (pl)	2012-12-31
CZ301282B6 (cs)	2009-12-30
MA25847A1 (fr)	2003-07-01
EP1328266A1 (fr)	2003-07-23
AR035071A1 (es)	2004-04-14
US20040022778A1 (en)	2004-02-05
CA2426625C (fr)	2010-06-01
WO2002034259A1 (fr)	2002-05-02
JP2004512302A (ja)	2004-04-22
EE200300165A (et)	2003-06-16
DK1328266T3 (da)	2006-06-06
IL155524A0 (en)	2003-11-23
CA2426625A1 (fr)	2002-05-02
KR20030055276A (ko)	2003-07-02
BG65979B1 (bg)	2010-08-31
PL361635A1 (en)	2004-10-04
EP1328266B1 (fr)	2006-02-01
ATE316787T1 (de)	2006-02-15
DE60117046T2 (de)	2006-09-28
AU2176502A (en)	2002-05-06
NO20031851L (no)	2003-06-24
NO20031851D0 (no)	2003-04-24
TNSN01151A1 (en)	2005-11-10
MXPA03003733A (es)	2004-10-15
SK5082003A3 (en)	2003-11-04
NO332260B1 (no)	2012-08-13
BG107765A (bg)	2004-02-27
KR100862129B1 (ko)	2008-10-09
IL155524A (en)	2008-08-07
RU2003111175A (ru)	2004-09-10
CN1220488C (zh)	2005-09-28
EE05281B1 (et)	2010-04-15
HK1057340A1 (en)	2004-04-02
US7410983B2 (en)	2008-08-12
CN1471390A (zh)	2004-01-28
PT1328266E (pt)	2006-05-31
HUP0303566A3 (en)	2005-05-30
ES2257457T3 (es)	2006-08-01
DE60117046D1 (de)	2006-04-13
DZ3442A1 (fr)	2002-05-02
HUP0303566A2 (hu)	2004-03-01
JP4236464B2 (ja)	2009-03-11

Publication	Publication Date	Title
EP1328266B1 (fr)	2006-02-01	Combinaison de fenofibrate et de coenzyme q10 permettant de traiter un dysfonctionnement endothelial
AU705002B2 (en)	1999-05-13	Method and formulation of stimulating nitric oxide synthesis
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