SK2992003A3 - Processes for preparing cilostazol - Google Patents

Processes for preparing cilostazol Download PDF

Info

Publication number
SK2992003A3
SK2992003A3 SK299-2003A SK2992003A SK2992003A3 SK 2992003 A3 SK2992003 A3 SK 2992003A3 SK 2992003 A SK2992003 A SK 2992003A SK 2992003 A3 SK2992003 A3 SK 2992003A3
Authority
SK
Slovakia
Prior art keywords
tetrazole
cilostazol
cyclohexyl
alkali metal
dihydroquinoline
Prior art date
Application number
SK299-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Marioara Mendelovichi
Nina Finkelstein
Gideon Pilarksi
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of SK2992003A3 publication Critical patent/SK2992003A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
SK299-2003A 2000-08-14 2001-08-14 Processes for preparing cilostazol SK2992003A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22536200P 2000-08-14 2000-08-14
PCT/US2001/025398 WO2002014283A1 (en) 2000-08-14 2001-08-14 Processes for preparing cilostazol

Publications (1)

Publication Number Publication Date
SK2992003A3 true SK2992003A3 (en) 2003-10-07

Family

ID=22844569

Family Applications (1)

Application Number Title Priority Date Filing Date
SK299-2003A SK2992003A3 (en) 2000-08-14 2001-08-14 Processes for preparing cilostazol

Country Status (17)

Country Link
EP (1) EP1311485A4 (is)
JP (2) JP3845059B2 (is)
KR (1) KR20030024865A (is)
CN (1) CN1469864A (is)
AU (1) AU2001284887A1 (is)
CA (1) CA2419181A1 (is)
CZ (1) CZ2003667A3 (is)
HK (1) HK1053116A1 (is)
HU (1) HUP0302688A2 (is)
IL (1) IL154458A0 (is)
IS (1) IS6716A (is)
MX (1) MXPA03001470A (is)
NO (1) NO20030699L (is)
NZ (1) NZ524363A (is)
PL (1) PL365672A1 (is)
SK (1) SK2992003A3 (is)
WO (1) WO2002014283A1 (is)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045547A1 (en) 2001-05-02 2003-03-06 Shinji Aki Process for producing carbostyril derivatives
US7399864B2 (en) 2001-05-02 2008-07-15 Otsuka Pharmaceutical Co., Ltd. Process for producing carbostyril derivatives
US20050101631A1 (en) 2002-08-01 2005-05-12 Otsuka Pharmaceuticals Company Process for producing carbostyril derivatives
EP1489080B1 (en) 2002-09-10 2011-01-26 Otsuka Pharmaceutical Co., Ltd. Process for producing cilostazol
WO2006001846A1 (en) * 2004-02-05 2006-01-05 Teva Pharmaceutical Industries Ltd. Method of making 7-(4-bromobutoxy)-3,4-dihydrocarbostyril
KR100633232B1 (ko) * 2004-08-25 2006-10-11 주식회사유한양행 신규한 6-[4-(1-시클로헥실-1ｈ-테트라졸-5-일)부톡시]-3,4-디히드로-2(1ｈ)-퀴놀리논 정제방법
US20070270590A1 (en) * 2006-04-20 2007-11-22 Marioara Mendelovici Methods for preparing eszopiclone crystalline form a, substantially pure eszopiclone and optically enriched eszopiclone
TW200848041A (en) 2007-03-30 2008-12-16 Otsuka Pharma Co Ltd A medicament for treating schizophrenia comprising cilostazol
ES2401914T3 (es) 2007-04-25 2013-04-25 Concert Pharmaceuticals Inc. Análogos de Cilostazol
CN101434598B (zh) * 2008-12-19 2012-11-07 重庆康乐制药有限公司 西洛他唑的制备方法
CN102086190B (zh) * 2011-01-28 2013-07-10 海南美兰史克制药有限公司 西洛他唑化合物及其制法
CN107382970A (zh) * 2017-07-26 2017-11-24 浙江金立源药业有限公司 一种西洛他唑的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535019A (en) * 1978-09-01 1980-03-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPH01265051A (ja) * 1988-04-14 1989-10-23 Fuji Photo Film Co Ltd ジアリールオキシアルカン製造方法

Also Published As

Publication number Publication date
EP1311485A1 (en) 2003-05-21
JP3845059B2 (ja) 2006-11-15
NZ524363A (en) 2004-03-26
CZ2003667A3 (cs) 2003-08-13
HUP0302688A2 (hu) 2003-12-29
JP2004506043A (ja) 2004-02-26
IS6716A (is) 2003-02-13
CA2419181A1 (en) 2002-02-21
NO20030699D0 (no) 2003-02-13
KR20030024865A (ko) 2003-03-26
HK1053116A1 (zh) 2003-10-10
EP1311485A4 (en) 2004-05-12
WO2002014283A1 (en) 2002-02-21
JP2005350474A (ja) 2005-12-22
MXPA03001470A (es) 2005-06-30
AU2001284887A1 (en) 2002-02-25
PL365672A1 (en) 2005-01-10
CN1469864A (zh) 2004-01-21
NO20030699L (no) 2003-04-10
IL154458A0 (en) 2003-09-17

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