SK3242002A3 - Calcium complex of phosphorus containing ethylenediamine derivatives - Google Patents
Calcium complex of phosphorus containing ethylenediamine derivatives Download PDFInfo
- Publication number
- SK3242002A3 SK3242002A3 SK324-2002A SK3242002A SK3242002A3 SK 3242002 A3 SK3242002 A3 SK 3242002A3 SK 3242002 A SK3242002 A SK 3242002A SK 3242002 A3 SK3242002 A3 SK 3242002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- kappa
- cap
- carboxy
- methyl
- bis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
- A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Detergent Compositions (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Absorbent Articles And Supports Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19944893A DE19944893C2 (de) | 1999-09-09 | 1999-09-09 | Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-. kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6, .kappa.N9,.kappa.O11]1-oxidato(6-)]-, hexahydrogen, dessen Salze und diese Komplexe enthaltende pharmazeutische Mittel |
| PCT/EP2000/008694 WO2001018011A1 (en) | 1999-09-09 | 2000-09-06 | Calcium complex of phosphorus containing ethylenediamine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK3242002A3 true SK3242002A3 (en) | 2002-10-08 |
Family
ID=7922563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK324-2002A SK3242002A3 (en) | 1999-09-09 | 2000-09-06 | Calcium complex of phosphorus containing ethylenediamine derivatives |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1210353B1 (sr) |
| JP (1) | JP2003508537A (sr) |
| KR (1) | KR100650090B1 (sr) |
| CN (1) | CN100341883C (sr) |
| AT (1) | ATE245159T1 (sr) |
| AU (1) | AU783982B2 (sr) |
| BG (1) | BG65280B1 (sr) |
| BR (1) | BR0013871A (sr) |
| CA (1) | CA2380766C (sr) |
| CZ (1) | CZ2002834A3 (sr) |
| DE (2) | DE19964224B4 (sr) |
| DK (1) | DK1210353T3 (sr) |
| EE (1) | EE05106B1 (sr) |
| ES (1) | ES2202178T3 (sr) |
| HR (1) | HRP20020302B1 (sr) |
| HU (1) | HUP0202873A3 (sr) |
| IL (1) | IL148563A (sr) |
| MX (1) | MXPA02001583A (sr) |
| NO (1) | NO20021167L (sr) |
| NZ (1) | NZ517708A (sr) |
| PL (1) | PL354749A1 (sr) |
| PT (1) | PT1210353E (sr) |
| RS (1) | RS50125B (sr) |
| RU (1) | RU2247727C2 (sr) |
| SK (1) | SK3242002A3 (sr) |
| TW (1) | TWI263641B (sr) |
| UA (1) | UA74165C2 (sr) |
| WO (1) | WO2001018011A1 (sr) |
| ZA (1) | ZA200202742B (sr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201514188A (zh) * | 2013-03-13 | 2015-04-16 | Lantheus Medical Imaging Inc | 製備釓磷維塞三鈉單水合物之方法 |
| WO2021122941A1 (en) | 2019-12-20 | 2021-06-24 | Bracco Imaging Spa | Calcium bopta complex |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
| TW319763B (sr) * | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| US5919967A (en) * | 1997-04-11 | 1999-07-06 | Epix Medical, Inc. | Process for synthesizing phosphodiesters |
-
1999
- 1999-09-09 DE DE19964224A patent/DE19964224B4/de not_active Expired - Fee Related
-
2000
- 2000-06-09 UA UA2002042826A patent/UA74165C2/uk unknown
- 2000-09-06 NZ NZ517708A patent/NZ517708A/en unknown
- 2000-09-06 HU HU0202873A patent/HUP0202873A3/hu unknown
- 2000-09-06 CZ CZ2002834A patent/CZ2002834A3/cs unknown
- 2000-09-06 BR BR0013871-1A patent/BR0013871A/pt not_active Application Discontinuation
- 2000-09-06 EP EP00967650A patent/EP1210353B1/en not_active Revoked
- 2000-09-06 MX MXPA02001583A patent/MXPA02001583A/es active IP Right Grant
- 2000-09-06 WO PCT/EP2000/008694 patent/WO2001018011A1/en not_active Ceased
- 2000-09-06 HR HR20020302A patent/HRP20020302B1/xx not_active IP Right Cessation
- 2000-09-06 JP JP2001522234A patent/JP2003508537A/ja active Pending
- 2000-09-06 AU AU77749/00A patent/AU783982B2/en not_active Ceased
- 2000-09-06 ES ES00967650T patent/ES2202178T3/es not_active Expired - Lifetime
- 2000-09-06 KR KR1020027003005A patent/KR100650090B1/ko not_active Expired - Fee Related
- 2000-09-06 PL PL00354749A patent/PL354749A1/xx unknown
- 2000-09-06 AT AT00967650T patent/ATE245159T1/de not_active IP Right Cessation
- 2000-09-06 EE EEP200200090A patent/EE05106B1/xx not_active IP Right Cessation
- 2000-09-06 DE DE60003931T patent/DE60003931T2/de not_active Revoked
- 2000-09-06 RU RU2002107456/04A patent/RU2247727C2/ru not_active IP Right Cessation
- 2000-09-06 CA CA002380766A patent/CA2380766C/en not_active Expired - Fee Related
- 2000-09-06 DK DK00967650T patent/DK1210353T3/da active
- 2000-09-06 SK SK324-2002A patent/SK3242002A3/sk not_active Application Discontinuation
- 2000-09-06 CN CNB008126879A patent/CN100341883C/zh not_active Expired - Fee Related
- 2000-09-06 RS YUP-161/02A patent/RS50125B/sr unknown
- 2000-09-06 IL IL14856300A patent/IL148563A/en not_active IP Right Cessation
- 2000-09-06 PT PT00967650T patent/PT1210353E/pt unknown
- 2000-09-28 TW TW089118643A patent/TWI263641B/zh active
-
2002
- 2002-03-07 BG BG106488A patent/BG65280B1/bg unknown
- 2002-03-08 NO NO20021167A patent/NO20021167L/no not_active Application Discontinuation
- 2002-04-08 ZA ZA200202742A patent/ZA200202742B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3401052C2 (de) | Diagnostische Mittel | |
| EP0485045B1 (de) | Mono-N-substituierte 1,4,7,10-Tetraazacyclododecan-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel | |
| EP0405704B1 (de) | Derivatisierte DTPA-Komplexe, diese Verbindungen enthaltende pharmazeutische Mittel, ihre Verwendung und Verfahren zu deren Herstellung | |
| EP0874645A2 (de) | Perfluoralkylhaltige metallkomplexe und ihre verwendung in der nmr-diagnostik | |
| DE3825040A1 (de) | 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel | |
| DE60207288T2 (de) | Gewebespezifische fluoreszierende chelate | |
| EP0680464B1 (de) | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung als nmr- und röntgenkontrastmittel und verfahren zu deren herstellung | |
| SK3242002A3 (en) | Calcium complex of phosphorus containing ethylenediamine derivatives | |
| US6559330B1 (en) | Calcium complex of [[(4r)-4-[bis{carboxy-.kappa.o)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.o)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.n6,.kappa.n9,.kappa.011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents | |
| EP1102770A1 (de) | Paramagnetische 3-,8-substituierte deuteroporphyrinderivate, diese enthaltende pharmazeutische mittel, verfahren zu ihrer herstellung und ihre verwendung für das nekrose- und infarkt-mr-imaging | |
| DE4340809A1 (de) | 1.4,710-Tetraazacyclododecan-Derivate, deren Verwendung, diese enthaltende pharmazeutische Mittel und Verfahren zu deren Herstellung | |
| US20030203879A1 (en) | Calcium complex of [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-.kappa.n]-6,9-bis[(carboxy.kappa.O)methyl]-1-[(4,4-diphenylcyclohexy)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-ylic-acid-.kappa.N6,.Kappa.N9,.Kappa 011]1-oxidato(6-)]-, hexahydrogen, its salts, pharmaceutical agents that contain these complexes, their use in treatment and as additives in diagnosis, as well as processes for the production of the complexes and agents | |
| EP1072604B1 (de) | Calcium-Komplex von (4R)-4-bis(carboxy-kappa.O)methyl amino-.kappa.N-6,9-bis (carboxy-.kappa.O)methyl-1-(4,4-diphenylcyclohexyl)oxy-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6,.kappa.N9,.kappa.O11 1-oxidato(6-)-,hexahydrogen, dessen Salze, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Therapie und als Zusatzstoff in der Diagnostik sowie Verfahren zur Herstellung der Komplexe und Mittel | |
| DE4403039A1 (de) | Oktaazamakrocyclen, deren Metallkomplexe, Verfahren zu deren Herstellung, diese Komplexe enthaltende Mittel sowie deren Verwendung in Diagnostik und Therapie | |
| DE19944893C2 (de) | Calcium-Komplex von [[(4R)-4-[bis[(carboxy-.kappa.O)methyl]amino-. kappa.N]-6,9-bis[(carboxy-.kappa.O)methyl]-1-[(4,4-diphenylcyclohexyl)oxy]-1-hydroxy-2-oxa-6,9-diaza-1-phosphaundecan-11-yl-säure-.kappa.N6, .kappa.N9,.kappa.O11]1-oxidato(6-)]-, hexahydrogen, dessen Salze und diese Komplexe enthaltende pharmazeutische Mittel | |
| WO1998013338A1 (de) | Ionenpaare, verfahren zu ihrer herstellung und ihre verwendung als kontrastmittel | |
| DE19546234C1 (de) | Neue makrobicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese makrobicyclischen Verbindungen enthaltende pharmazeutische Mittel | |
| HK1002810B (en) | Dtpa-complexes derivatives, pharmaceutical compositions containing them, their use and process for their preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC9A | Refused patent application |