SK69094A3 - Optical isomers of leukotriene antagonists and method of their separation - Google Patents

Optical isomers of leukotriene antagonists and method of their separation Download PDF

Info

Publication number
SK69094A3
SK69094A3 SK690-94A SK69094A SK69094A3 SK 69094 A3 SK69094 A3 SK 69094A3 SK 69094 A SK69094 A SK 69094A SK 69094 A3 SK69094 A3 SK 69094A3
Authority
SK
Slovakia
Prior art keywords
alkyl
salt
formula
radical
alkoxy
Prior art date
Application number
SK690-94A
Other languages
English (en)
Slovak (sk)
Inventor
Robert J Mills
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of SK69094A3 publication Critical patent/SK69094A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK690-94A 1991-12-12 1992-12-11 Optical isomers of leukotriene antagonists and method of their separation SK69094A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/806,031 US5214201A (en) 1991-12-12 1991-12-12 Crystallization of optical isomers of leukotriene antagonists
PCT/US1992/010583 WO1993012054A1 (en) 1991-12-12 1992-12-11 Crystallization of optical isomers of leukotriene antagonists

Publications (1)

Publication Number Publication Date
SK69094A3 true SK69094A3 (en) 1995-03-08

Family

ID=25193150

Family Applications (1)

Application Number Title Priority Date Filing Date
SK690-94A SK69094A3 (en) 1991-12-12 1992-12-11 Optical isomers of leukotriene antagonists and method of their separation

Country Status (21)

Country Link
US (1) US5214201A (cs)
EP (1) EP0638055A1 (cs)
JP (1) JPH07501823A (cs)
CN (1) CN1074212A (cs)
AP (1) AP371A (cs)
AU (1) AU3243993A (cs)
BG (1) BG98842A (cs)
BR (1) BR9207022A (cs)
CA (1) CA2125495A1 (cs)
CZ (1) CZ141294A3 (cs)
FI (1) FI942746A7 (cs)
HU (1) HUT70850A (cs)
IL (1) IL104077A0 (cs)
MA (1) MA22742A1 (cs)
MX (1) MX9207252A (cs)
NO (1) NO942187D0 (cs)
OA (1) OA10025A (cs)
SI (1) SI9200386A (cs)
SK (1) SK69094A3 (cs)
WO (1) WO1993012054A1 (cs)
ZA (1) ZA929677B (cs)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845272A (en) * 1987-07-10 1989-07-04 Kuraray Co., Ltd. Process for the optical resolution of (±)-cis or (±)-trans-permethric acid
IT1217988B (it) * 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
US4904822A (en) * 1988-02-19 1990-02-27 Kuraray Co., Ltd. Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid
IT1226300B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.
CA2018437A1 (en) * 1989-06-14 1990-12-14 James Simpson Frazee Leukotriene antagonists

Also Published As

Publication number Publication date
WO1993012054A1 (en) 1993-06-24
AU3243993A (en) 1993-07-19
JPH07501823A (ja) 1995-02-23
AP371A (en) 1994-11-10
BG98842A (bg) 1995-05-31
NO942187L (cs) 1994-06-10
SI9200386A (en) 1993-06-30
CN1074212A (zh) 1993-07-14
MA22742A1 (fr) 1993-07-01
BR9207022A (pt) 1995-12-12
ZA929677B (en) 1993-10-13
EP0638055A1 (en) 1995-02-15
HU9401744D0 (en) 1994-09-28
NO942187D0 (no) 1994-06-10
CA2125495A1 (en) 1993-06-24
FI942746A0 (fi) 1994-06-10
EP0638055A4 (en) 1994-10-19
AP9200462A0 (en) 1993-01-31
OA10025A (en) 1996-10-14
MX9207252A (es) 1993-07-01
US5214201A (en) 1993-05-25
CZ141294A3 (en) 1995-01-18
FI942746L (fi) 1994-06-10
IL104077A0 (en) 1993-05-13
FI942746A7 (fi) 1994-06-10
HUT70850A (en) 1995-11-28

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