SK7799A3 - Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses - Google Patents

Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses Download PDF

Info

Publication number: SK7799A3
Authority: SK; Slovakia
Prior art keywords: ige; hsa; polypeptide; leu; glu
Prior art date: 1996-07-26

Application number

SK77-99A

Other languages

English (en)

Slovak (sk)

Inventor

Mary E Digan

Philip Lake

Hermann Gram

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-26

Filing date

1997-07-25

Publication date

1999-07-12

1997-07-25 Application filed by Novartis Ag filed Critical Novartis Ag

1999-07-12 Publication of SK7799A3 publication Critical patent/SK7799A3/sk

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
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Wood Science & Technology (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SK77-99A 1996-07-26 1997-07-25 Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses SK7799A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US69021696A	1996-07-26	1996-07-26
PCT/EP1997/004066 WO1998004718A1 (en)	1996-07-26	1997-07-25	Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses

Publications (1)

Publication Number	Publication Date
SK7799A3 true SK7799A3 (en)	1999-07-12

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ID=24771594

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Application Number	Title	Priority Date	Filing Date
SK77-99A SK7799A3 (en)	1996-07-26	1997-07-25	Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses

Country Status (27)

Country	Link
EP (1)	EP0917581B1 (de)
JP (1)	JP3681402B2 (de)
KR (1)	KR100502879B1 (de)
CN (1)	CN1146664C (de)
AR (1)	AR008077A1 (de)
AT (1)	ATE383429T1 (de)
AU (1)	AU722069B2 (de)
BR (1)	BR9710605A (de)
CA (1)	CA2261562C (de)
CO (1)	CO4650184A1 (de)
CZ (1)	CZ297634B6 (de)
DE (1)	DE69738452T2 (de)
ES (1)	ES2300114T3 (de)
ID (1)	ID19420A (de)
IL (2)	IL128094A0 (de)
MY (1)	MY120425A (de)
NO (1)	NO323611B1 (de)
NZ (1)	NZ333908A (de)
PE (1)	PE99498A1 (de)
PL (1)	PL189415B1 (de)
PT (1)	PT917581E (de)
RU (1)	RU2209211C2 (de)
SK (1)	SK7799A3 (de)
TR (1)	TR199900155T2 (de)
TW (1)	TW565571B (de)
WO (1)	WO1998004718A1 (de)
ZA (1)	ZA976666B (de)

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EP1208194A2 (de) *	1999-08-09	2002-05-29	Genaissance Pharmaceuticals, Inc.	Isogene arzneimittel-ziele: polymorphismen des gens der immunglobulin e rezeptor i alpha untereinheit
JP2003530838A (ja)	2000-04-12	2003-10-21	ヒューマンゲノムサイエンシズインコーポレイテッド	アルブミン融合タンパク質
US6946134B1 (en)	2000-04-12	2005-09-20	Human Genome Sciences, Inc.	Albumin fusion proteins
DE10026998A1 (de) *	2000-05-31	2001-12-13	Fresenius Kabi De Gmbh	Verfahren zur Herstellung einer kosmetischen Zusammensetzung, die humanes Serum Albumin umfasst, welches aus transgenen nicht-menschlichen Säugern erhalten wurde
UA93662C2 (uk)	2000-12-07	2011-03-10	Эли Лилли Энд Компани	Гетерологічний пептидильований глюкагон-подібний білок та його застосування для виготовлення лікарського засобу для лікування пацієнтів, що страждають на ожиріння або інсулінонезалежний цукровий діабет
TWI329129B (en) *	2001-02-08	2010-08-21	Wyeth Corp	Modified and stabilized gdf propeptides and uses thereof
US7507413B2 (en)	2001-04-12	2009-03-24	Human Genome Sciences, Inc.	Albumin fusion proteins
ES2425738T3 (es)	2001-12-21	2013-10-17	Human Genome Sciences, Inc.	Proteínas de fusión de la albúmina
EP1594530A4 (de)	2003-01-22	2006-10-11	Human Genome Sciences Inc	Albuminfusionsproteine
JP5677972B2 (ja)	2008-11-18	2015-02-25	メリマックファーマシューティカルズインコーポレーティッド	ヒト血清アルブミンリンカーおよびそのコンジュゲート
DK2401383T3 (da)	2009-02-27	2013-12-16	Novartis Ag	Fremgangsmåder til udvælgelse af eukaryote celler, som udtrykker et heterologt protein
WO2012169735A2 (ko) *	2011-06-07	2012-12-13	(주)네오팜	FCεRI의 수용성 단편을 포함하는 복합체 및 이를 포함하는 IGE 매개 알레르기성 질환 치료용 조성물
RU2506271C2 (ru) *	2011-06-22	2014-02-10	Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН)	РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД А2, СЕЛЕКТИВНО СВЯЗЫВАЮЩИЙ HSA, РЕКОМБИНАНТНАЯ ДНК pa2, КОДИРУЮЩАЯ HSA-СВЯЗЫВАЮЩУЮ ЧАСТЬ ПОЛИПЕПТИДА A2, ЕГО ПРОДУЦЕНТ - РЕКОМБИНАНТНЫЙ ШТАММ Escherichia coli M15-A2, СОДЕРЖАЩИЙ РЕКОМБИНАНТНУЮ ПЛАЗМИДНУЮ ДНК pQE 32-pa2, ОБЕСПЕЧИВАЮЩУЮ ПОЛУЧЕНИЕ ПОЛИПЕПТИДА A2 И ПРИМЕНЕНИЕ ПОЛИПЕПТИДА А2 ДЛЯ ДИАГНОСТИКИ МИКРОАЛЬБУМИНУРИИ И ВЫДЕЛЕНИЯ HSA ИЗ СЫВОРОТКИ КРОВИ
US20150202287A1 (en)	2012-08-30	2015-07-23	Merrimack Pharmaceuticals, Inc.	Combination therapies comprising anti-erbb3 agents
JP2018515073A (ja) *	2015-05-04	2018-06-14	ラボラトワールフランセデュフラクショヌマンエデビオテクノロジーＬａｂｏｒａｔｏｉｒｅＦｒａｎｃａｉｓｄｕＦｒａｃｔｉｏｎｎｅｍｅｎｔｅｔｄｅｓＢｉｏｔｅｃｈｎｏｌｏｇｉｅｓ	Ｆｃ融合タンパク質のトランスジェニック産生
EP3192806A1 (de)	2016-01-13	2017-07-19	Affiris AG	Alpha-kette des hochaffinen ige-rezeptors (fceria)
JP7127859B2 (ja) *	2016-11-09	2022-08-30	ノースカロライナステートユニバーシティ	キメラタンパク質を用いたアレルギー疾患の治療
WO2019183437A1 (en)	2018-03-23	2019-09-26	North Carolina State University	Methods and compositions for antibody to high affinity receptor for ige
BR112022000246A2 (pt) *	2019-07-08	2022-02-22	Gi Innovation Inc	Dímero polipeptídico com elevado teor de ácido siálico, compreendendo o domínio extracelular da subunidade alfa do receptor fc de ige e composição farmacêutica compreendendo o mesmo
CN114302891A (zh) *	2019-07-08	2022-04-08	普罗根有限公司	新的il-10变体蛋白及其用途
CN111773392B (zh) *	2020-05-25	2023-04-07	河南省生物工程技术研究中心	一种人血白蛋白/寡核苷酸纳米颗粒及其制备方法和用途

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CA2059842A1 (en) *	1991-02-11	1992-08-12	Richard A. Chizzonite	Ige-receptor-antibodies

1997
- 1997-07-24 PE PE1997000662A patent/PE99498A1/es not_active Application Discontinuation
- 1997-07-24 MY MYPI97003371A patent/MY120425A/en unknown
- 1997-07-24 AR ARP970103340A patent/AR008077A1/es active IP Right Grant
- 1997-07-25 BR BR9710605A patent/BR9710605A/pt not_active IP Right Cessation
- 1997-07-25 SK SK77-99A patent/SK7799A3/sk unknown
- 1997-07-25 WO PCT/EP1997/004066 patent/WO1998004718A1/en not_active Ceased
- 1997-07-25 CO CO97042651A patent/CO4650184A1/es unknown
- 1997-07-25 DE DE69738452T patent/DE69738452T2/de not_active Expired - Lifetime
- 1997-07-25 ZA ZA976666A patent/ZA976666B/xx unknown
- 1997-07-25 JP JP50850498A patent/JP3681402B2/ja not_active Expired - Fee Related
- 1997-07-25 ID IDP972592A patent/ID19420A/id unknown
- 1997-07-25 KR KR10-1999-7000621A patent/KR100502879B1/ko not_active Expired - Fee Related
- 1997-07-25 PT PT97940030T patent/PT917581E/pt unknown
- 1997-07-25 EP EP97940030A patent/EP0917581B1/de not_active Expired - Lifetime
- 1997-07-25 ES ES97940030T patent/ES2300114T3/es not_active Expired - Lifetime
- 1997-07-25 AT AT97940030T patent/ATE383429T1/de active
- 1997-07-25 CN CNB971976597A patent/CN1146664C/zh not_active Expired - Fee Related
- 1997-07-25 NZ NZ333908A patent/NZ333908A/en unknown
- 1997-07-25 AU AU42025/97A patent/AU722069B2/en not_active Ceased
- 1997-07-25 RU RU99103326/13A patent/RU2209211C2/ru not_active IP Right Cessation
- 1997-07-25 CZ CZ0024699A patent/CZ297634B6/cs not_active IP Right Cessation
- 1997-07-25 CA CA2261562A patent/CA2261562C/en not_active Expired - Fee Related
- 1997-07-25 IL IL12809497A patent/IL128094A0/xx active IP Right Grant
- 1997-07-25 TR TR1999/00155T patent/TR199900155T2/xx unknown
- 1997-08-08 TW TW086111356A patent/TW565571B/zh not_active IP Right Cessation
1999
- 1999-01-18 IL IL128094A patent/IL128094A/en not_active IP Right Cessation
- 1999-01-25 PL PL97331356A patent/PL189415B1/pl not_active IP Right Cessation
- 1999-01-25 NO NO19990328A patent/NO323611B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP3681402B2 (ja)	2005-08-10
CZ24699A3 (cs)	1999-04-14
IL128094A0 (en)	1999-11-30
CA2261562C (en)	2011-04-05
AU722069B2 (en)	2000-07-20
PL189415B1 (pl)	2005-08-31
ES2300114T3 (es)	2008-06-01
CN1229439A (zh)	1999-09-22
IL128094A (en)	2006-08-20
NO990328L (no)	1999-02-19
AU4202597A (en)	1998-02-20
EP0917581B1 (de)	2008-01-09
CA2261562A1 (en)	1998-02-05
EP0917581A1 (de)	1999-05-26
DE69738452D1 (de)	2008-02-21
WO1998004718A1 (en)	1998-02-05
ATE383429T1 (de)	2008-01-15
ID19420A (id)	1998-07-09
CO4650184A1 (es)	1998-09-03
KR100502879B1 (ko)	2005-07-25
JP2000516089A (ja)	2000-12-05
NO990328D0 (no)	1999-01-25
MY120425A (en)	2005-10-31
DE69738452T2 (de)	2008-12-24
HK1020352A1 (en)	2000-04-14
KR20000029563A (ko)	2000-05-25
NO323611B1 (no)	2007-06-18
TW565571B (en)	2003-12-11
PE99498A1 (es)	1999-01-21
ZA976666B (en)	1999-01-25
CN1146664C (zh)	2004-04-21
TR199900155T2 (xx)	2000-08-21
RU2209211C2 (ru)	2003-07-27
AR008077A1 (es)	1999-12-09
PT917581E (pt)	2008-04-11
NZ333908A (en)	1999-10-28
BR9710605A (pt)	1999-08-17
CZ297634B6 (cs)	2007-02-21
PL331356A1 (en)	1999-07-05

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SK7799A3 (en)	1999-07-12	Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses
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EP2427207A2 (de)	2012-03-14	Fgf21-mutanten und ihre verwendungen
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HK40110187A (en)	2024-12-20	Fgf21 mutants and uses thereof
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