SK81899A3 - Polypeptides of the "basic-helix-loop-helix" bhlh family, corresponding nucleic acid sequences - Google Patents
Polypeptides of the "basic-helix-loop-helix" bhlh family, corresponding nucleic acid sequences Download PDFInfo
- Publication number
- SK81899A3 SK81899A3 SK818-99A SK81899A SK81899A3 SK 81899 A3 SK81899 A3 SK 81899A3 SK 81899 A SK81899 A SK 81899A SK 81899 A3 SK81899 A3 SK 81899A3
- Authority
- SK
- Slovakia
- Prior art keywords
- sequence
- nucleic acid
- seq
- bhlh
- helix
- Prior art date
Links
- 150000007523 nucleic acids Chemical group 0.000 title claims description 29
- 108090000765 processed proteins & peptides Proteins 0.000 title claims description 29
- 229920001184 polypeptide Polymers 0.000 title claims description 23
- 102000004196 processed proteins & peptides Human genes 0.000 title claims description 23
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 45
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- 239000002773 nucleotide Substances 0.000 claims description 13
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- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 9
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- 108010027344 Basic Helix-Loop-Helix Transcription Factors Proteins 0.000 abstract description 13
- 102000018720 Basic Helix-Loop-Helix Transcription Factors Human genes 0.000 abstract description 13
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- 125000003275 alpha amino acid group Chemical group 0.000 description 8
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- 108091092195 Intron Proteins 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 241000701168 Murine adenovirus 1 Species 0.000 description 1
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- 101100163890 Rattus norvegicus Ascl2 gene Proteins 0.000 description 1
- 101000606117 Rattus norvegicus Tyrosine 3-monooxygenase Proteins 0.000 description 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 description 1
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- 238000012300 Sequence Analysis Methods 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
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- 238000000137 annealing Methods 0.000 description 1
- 239000000074 antisense oligonucleotide Substances 0.000 description 1
- 238000012230 antisense oligonucleotides Methods 0.000 description 1
- 108091067133 bHLH protein family Proteins 0.000 description 1
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- 239000000872 buffer Substances 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
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- 108020001507 fusion proteins Proteins 0.000 description 1
- 102000037865 fusion proteins Human genes 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 230000003037 histogenic effect Effects 0.000 description 1
- 210000003016 hypothalamus Anatomy 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000001823 molecular biology technique Methods 0.000 description 1
- 238000007857 nested PCR Methods 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 210000000276 neural tube Anatomy 0.000 description 1
- 230000007472 neurodevelopment Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
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- 230000003362 replicative effect Effects 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
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- 210000001202 rhombencephalon Anatomy 0.000 description 1
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- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/028—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a herpesvirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9615651A FR2757524B1 (fr) | 1996-12-19 | 1996-12-19 | Polypeptides de la famille bhlh, sequences d'acides nucleiques correspondantes |
| PCT/FR1997/002368 WO1998027206A2 (fr) | 1996-12-19 | 1997-12-19 | Polypeptides de la famille 'basic helix-loop-helix' bhlh, sequences d'acides nucleiques correspondantes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK81899A3 true SK81899A3 (en) | 2000-05-16 |
Family
ID=9498862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK818-99A SK81899A3 (en) | 1996-12-19 | 1997-12-19 | Polypeptides of the "basic-helix-loop-helix" bhlh family, corresponding nucleic acid sequences |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6998474B1 (fr) |
| EP (1) | EP0946724A2 (fr) |
| JP (1) | JP2001510464A (fr) |
| KR (1) | KR20000057698A (fr) |
| AU (1) | AU732438B2 (fr) |
| BR (1) | BR9713968A (fr) |
| CA (1) | CA2275454A1 (fr) |
| CZ (1) | CZ219499A3 (fr) |
| FR (1) | FR2757524B1 (fr) |
| HU (1) | HU224305B1 (fr) |
| IL (1) | IL130302A0 (fr) |
| NO (1) | NO993029L (fr) |
| SK (1) | SK81899A3 (fr) |
| WO (1) | WO1998027206A2 (fr) |
| ZA (1) | ZA9711401B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP495598A0 (en) | 1998-07-30 | 1998-08-20 | Walter And Eliza Hall Institute Of Medical Research, The | A novel regulatory molecule and genetic sequences encoding same |
| DE60034877T2 (de) * | 1999-04-06 | 2008-01-17 | The Regents Of The University Of California, Oakland | MENSCHLICHE, FüR NEUROGENIN 3 KODIERENDE NUKLEOTIDSEQUENZEN |
| EP1354951B1 (fr) * | 2000-12-27 | 2008-06-04 | Sumitomo Chemical Company, Limited | Methode d'examen de la capacite a controler la plasticite des cellules nerveuses |
| US20150315607A1 (en) * | 2014-01-15 | 2015-11-05 | Academia Sinica | Mutated nucleotide molecule, and transformed plant cells and plants comprising the same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5695995A (en) | 1994-05-06 | 1997-12-09 | Fred Hutchinson Cancer Research Center | Neurogenic differentiation (neurod) genes |
| EP0759938A4 (fr) * | 1994-05-06 | 1999-10-27 | Hutchinson Fred Cancer Res | Proteines et genes de differentiation neurogene (neuro d) |
| US6566496B1 (en) * | 1996-09-27 | 2003-05-20 | California Institute Of Technology | Neurogenin |
-
1996
- 1996-12-19 FR FR9615651A patent/FR2757524B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-18 ZA ZA9711401A patent/ZA9711401B/xx unknown
- 1997-12-19 BR BR9713968-8A patent/BR9713968A/pt not_active IP Right Cessation
- 1997-12-19 HU HU0001184A patent/HU224305B1/hu not_active IP Right Cessation
- 1997-12-19 CZ CZ992194A patent/CZ219499A3/cs unknown
- 1997-12-19 JP JP52741598A patent/JP2001510464A/ja not_active Ceased
- 1997-12-19 EP EP97952961A patent/EP0946724A2/fr not_active Withdrawn
- 1997-12-19 IL IL13030297A patent/IL130302A0/xx unknown
- 1997-12-19 CA CA002275454A patent/CA2275454A1/fr not_active Abandoned
- 1997-12-19 AU AU56673/98A patent/AU732438B2/en not_active Ceased
- 1997-12-19 WO PCT/FR1997/002368 patent/WO1998027206A2/fr not_active Ceased
- 1997-12-19 SK SK818-99A patent/SK81899A3/sk unknown
- 1997-12-19 KR KR1019990705560A patent/KR20000057698A/ko not_active Ceased
-
1999
- 1999-06-18 NO NO993029A patent/NO993029L/no not_active Application Discontinuation
-
2000
- 2000-06-16 US US09/595,947 patent/US6998474B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL130302A0 (en) | 2000-06-01 |
| BR9713968A (pt) | 2000-04-11 |
| WO1998027206A2 (fr) | 1998-06-25 |
| JP2001510464A (ja) | 2001-07-31 |
| AU732438B2 (en) | 2001-04-26 |
| HUP0001184A3 (en) | 2002-01-28 |
| WO1998027206A3 (fr) | 1998-10-01 |
| FR2757524A1 (fr) | 1998-06-26 |
| HU224305B1 (hu) | 2005-07-28 |
| EP0946724A2 (fr) | 1999-10-06 |
| FR2757524B1 (fr) | 1999-01-29 |
| NO993029L (no) | 1999-08-16 |
| ZA9711401B (en) | 1998-06-25 |
| CA2275454A1 (fr) | 1998-06-25 |
| HUP0001184A2 (hu) | 2000-08-28 |
| AU5667398A (en) | 1998-07-15 |
| US6998474B1 (en) | 2006-02-14 |
| CZ219499A3 (cs) | 1999-10-13 |
| KR20000057698A (ko) | 2000-09-25 |
| NO993029D0 (no) | 1999-06-18 |
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