BR9713968A - Polipeptìdeo do tipo bhlh dotado de uma atividade transcricional, sequência de ácidos nucleicos, vetor, utilização de polipeptìdeos, composição farmacêutica, e, utilização de uma sequência - Google Patents

Polipeptìdeo do tipo bhlh dotado de uma atividade transcricional, sequência de ácidos nucleicos, vetor, utilização de polipeptìdeos, composição farmacêutica, e, utilização de uma sequência

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Publication number
BR9713968A
BR9713968A BR9713968-8A BR9713968A BR9713968A BR 9713968 A BR9713968 A BR 9713968A BR 9713968 A BR9713968 A BR 9713968A BR 9713968 A BR9713968 A BR 9713968A
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BR
Brazil
Prior art keywords
sequence
vector
nucleic acid
pharmaceutical composition
transcriptional activity
Prior art date
Application number
BR9713968-8A
Other languages
English (en)
Inventor
Christine Icard-Liepkalns
Jacques Mallet
Philippe Ravassard
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of BR9713968A publication Critical patent/BR9713968A/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/028Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a herpesvirus

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"POLIPETìDEO DO TIPO BHLH DOTADO DE UMA ATIVIDADE TRANSCRICIONAL, SEQUêNCIA DE áCIDOS NUCLEICOS, VETOR, UTILIZAçãO DE POLIPEPTìDEOS, COMPOSIçãO FARMACêUTICA, E, UTILIZAçãO DE UMA SEQUêNCIA". A presente invenção refere-se a uma nova proteína de tipo bHLH e à sequência nucleica codificada correspondente. Ela visa igualmente vetores de expressão integrando a dita sequência e a utilização desta sequência ou proteína para fins terapêuticos.
BR9713968-8A 1996-12-19 1997-12-19 Polipeptìdeo do tipo bhlh dotado de uma atividade transcricional, sequência de ácidos nucleicos, vetor, utilização de polipeptìdeos, composição farmacêutica, e, utilização de uma sequência BR9713968A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615651A FR2757524B1 (fr) 1996-12-19 1996-12-19 Polypeptides de la famille bhlh, sequences d'acides nucleiques correspondantes
PCT/FR1997/002368 WO1998027206A2 (fr) 1996-12-19 1997-12-19 Polypeptides de la famille 'basic helix-loop-helix' bhlh, sequences d'acides nucleiques correspondantes

Publications (1)

Publication Number Publication Date
BR9713968A true BR9713968A (pt) 2000-04-11

Family

ID=9498862

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9713968-8A BR9713968A (pt) 1996-12-19 1997-12-19 Polipeptìdeo do tipo bhlh dotado de uma atividade transcricional, sequência de ácidos nucleicos, vetor, utilização de polipeptìdeos, composição farmacêutica, e, utilização de uma sequência

Country Status (15)

Country Link
US (1) US6998474B1 (pt)
EP (1) EP0946724A2 (pt)
JP (1) JP2001510464A (pt)
KR (1) KR20000057698A (pt)
AU (1) AU732438B2 (pt)
BR (1) BR9713968A (pt)
CA (1) CA2275454A1 (pt)
CZ (1) CZ219499A3 (pt)
FR (1) FR2757524B1 (pt)
HU (1) HU224305B1 (pt)
IL (1) IL130302A0 (pt)
NO (1) NO993029L (pt)
SK (1) SK81899A3 (pt)
WO (1) WO1998027206A2 (pt)
ZA (1) ZA9711401B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP495598A0 (en) 1998-07-30 1998-08-20 Walter And Eliza Hall Institute Of Medical Research, The A novel regulatory molecule and genetic sequences encoding same
DE60034877T2 (de) * 1999-04-06 2008-01-17 The Regents Of The University Of California, Oakland MENSCHLICHE, FüR NEUROGENIN 3 KODIERENDE NUKLEOTIDSEQUENZEN
EP1354951B1 (en) * 2000-12-27 2008-06-04 Sumitomo Chemical Company, Limited Method of examining ability to control nerve cell plasticity
US20150315607A1 (en) * 2014-01-15 2015-11-05 Academia Sinica Mutated nucleotide molecule, and transformed plant cells and plants comprising the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695995A (en) 1994-05-06 1997-12-09 Fred Hutchinson Cancer Research Center Neurogenic differentiation (neurod) genes
EP0759938A4 (en) * 1994-05-06 1999-10-27 Hutchinson Fred Cancer Res PROTEINS AND NEUROGENIC DIFFERENTIATION GENES (NEURO D)
US6566496B1 (en) * 1996-09-27 2003-05-20 California Institute Of Technology Neurogenin

Also Published As

Publication number Publication date
IL130302A0 (en) 2000-06-01
WO1998027206A2 (fr) 1998-06-25
JP2001510464A (ja) 2001-07-31
AU732438B2 (en) 2001-04-26
HUP0001184A3 (en) 2002-01-28
WO1998027206A3 (fr) 1998-10-01
FR2757524A1 (fr) 1998-06-26
HU224305B1 (hu) 2005-07-28
EP0946724A2 (fr) 1999-10-06
FR2757524B1 (fr) 1999-01-29
NO993029L (no) 1999-08-16
ZA9711401B (en) 1998-06-25
CA2275454A1 (fr) 1998-06-25
HUP0001184A2 (hu) 2000-08-28
AU5667398A (en) 1998-07-15
US6998474B1 (en) 2006-02-14
SK81899A3 (en) 2000-05-16
CZ219499A3 (cs) 1999-10-13
KR20000057698A (ko) 2000-09-25
NO993029D0 (no) 1999-06-18

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1922 DE 06/11/2007.