SK852012A3 - Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu - Google Patents

Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu Download PDF

Info

Publication number: SK852012A3
Authority: SK; Slovakia
Prior art keywords: glucan; weight; suspension; beta; water
Prior art date: 2012-10-26

Application number

SK85-2012A

Other languages

English (en)

Slovak (sk)

Inventor

Matilda Matznerová

Original Assignee

Matilda Matznerová

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-10-26

Filing date

2012-10-26

Publication date

2014-06-03

2012-10-26 Application filed by Matilda Matznerová filed Critical Matilda Matznerová

2012-10-26 Priority to SK85-2012A priority Critical patent/SK852012A3/sk

2013-05-27 Priority to ATGM8023/2015U priority patent/AT14719U1/de

2013-05-27 Priority to ATA433/2013A priority patent/AT513524A1/de

2014-06-03 Publication of SK852012A3 publication Critical patent/SK852012A3/sk

Links

238000000034 method Methods 0.000 title claims abstract description 29
229920001503 Glucan Polymers 0.000 title claims description 49
230000008569 process Effects 0.000 title claims description 11
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 28
KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 claims abstract description 28
HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 27
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 27
239000000725 suspension Substances 0.000 claims abstract description 26
240000001462 Pleurotus ostreatus Species 0.000 claims abstract description 15
235000001603 Pleurotus ostreatus Nutrition 0.000 claims abstract description 15
238000005406 washing Methods 0.000 claims abstract description 15
239000007864 aqueous solution Substances 0.000 claims abstract description 14
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims abstract description 10
239000007844 bleaching agent Substances 0.000 claims abstract description 9
239000012153 distilled water Substances 0.000 claims abstract description 7
VBIXEXWLHSRNKB-UHFFFAOYSA-N ammonium oxalate Chemical compound [NH4+].[NH4+].[O-]C(=O)C([O-])=O VBIXEXWLHSRNKB-UHFFFAOYSA-N 0.000 claims abstract description 6
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 5
150000008044 alkali metal hydroxides Chemical class 0.000 claims abstract description 3
239000012736 aqueous medium Substances 0.000 claims abstract 2
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 25
238000004061 bleaching Methods 0.000 claims description 16
OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 claims description 14
-1 alkali metal bicarbonate Chemical class 0.000 claims description 13
239000000243 solution Substances 0.000 claims description 10
239000004155 Chlorine dioxide Substances 0.000 claims description 7
SCKXCAADGDQQCS-UHFFFAOYSA-N Performic acid Chemical compound OOC=O SCKXCAADGDQQCS-UHFFFAOYSA-N 0.000 claims description 7
235000019398 chlorine dioxide Nutrition 0.000 claims description 7
239000003651 drinking water Substances 0.000 claims description 7
238000011282 treatment Methods 0.000 claims description 7
235000007685 Pleurotus columbinus Nutrition 0.000 claims description 6
150000001447 alkali salts Chemical class 0.000 claims description 6
XXQBEVHPUKOQEO-UHFFFAOYSA-N potassium superoxide Chemical compound [K+].[K+].[O-][O-] XXQBEVHPUKOQEO-UHFFFAOYSA-N 0.000 claims description 6
229910052783 alkali metal Inorganic materials 0.000 claims description 5
238000004108 freeze drying Methods 0.000 claims description 5
239000000203 mixture Substances 0.000 claims description 5
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 4
230000018044 dehydration Effects 0.000 claims description 4
238000006297 dehydration reaction Methods 0.000 claims description 4
235000016709 nutrition Nutrition 0.000 claims description 4
239000007800 oxidant agent Substances 0.000 claims description 4
239000000654 additive Substances 0.000 claims description 3
230000000996 additive effect Effects 0.000 claims description 3
239000007900 aqueous suspension Substances 0.000 claims description 3
239000003153 chemical reaction reagent Substances 0.000 claims description 3
238000009472 formulation Methods 0.000 claims description 3
159000000011 group IA salts Chemical class 0.000 claims description 3
230000003308 immunostimulating effect Effects 0.000 claims description 3
PFUVRDFDKPNGAV-UHFFFAOYSA-N sodium peroxide Chemical compound [Na+].[Na+].[O-][O-] PFUVRDFDKPNGAV-UHFFFAOYSA-N 0.000 claims description 3
239000000126 substance Substances 0.000 claims description 3
230000001225 therapeutic effect Effects 0.000 claims description 3
239000002253 acid Substances 0.000 claims description 2
229910000288 alkali metal carbonate Inorganic materials 0.000 claims description 2
150000008041 alkali metal carbonates Chemical class 0.000 claims description 2
150000004973 alkali metal peroxides Chemical class 0.000 claims description 2
150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 2
239000003795 chemical substances by application Substances 0.000 claims description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims description 2
230000001590 oxidative effect Effects 0.000 claims description 2
238000000926 separation method Methods 0.000 claims description 2
239000002904 solvent Substances 0.000 claims description 2
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 1
230000035622 drinking Effects 0.000 claims 1
150000004687 hexahydrates Chemical class 0.000 claims 1
238000012958 reprocessing Methods 0.000 claims 1
FYGDTMLNYKFZSV-WFYNLLPOSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,3s,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-WFYNLLPOSA-N 0.000 abstract description 25
238000000605 extraction Methods 0.000 abstract description 8
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical class OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
150000004649 carbonic acid derivatives Chemical class 0.000 abstract 1
238000004537 pulping Methods 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 28
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 26
229920002498 Beta-glucan Polymers 0.000 description 26
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 16
229920002101 Chitin Polymers 0.000 description 14
229910052757 nitrogen Inorganic materials 0.000 description 13
239000011734 sodium Substances 0.000 description 9
229910000029 sodium carbonate Inorganic materials 0.000 description 8
235000013339 cereals Nutrition 0.000 description 6
235000020188 drinking water Nutrition 0.000 description 6
239000000047 product Substances 0.000 description 6
206010028980 Neoplasm Diseases 0.000 description 4
201000011510 cancer Diseases 0.000 description 4
238000002955 isolation Methods 0.000 description 4
239000002245 particle Substances 0.000 description 4
102000004169 proteins and genes Human genes 0.000 description 4
108090000623 proteins and genes Proteins 0.000 description 4
238000000746 purification Methods 0.000 description 4
ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
BDAGIHXWWSANSR-UHFFFAOYSA-M Formate Chemical compound [O-]C=O BDAGIHXWWSANSR-UHFFFAOYSA-M 0.000 description 3
OYNLAAXHIJNWOH-UHFFFAOYSA-N O.O.O.O.O.O.[Cl] Chemical compound O.O.O.O.O.O.[Cl] OYNLAAXHIJNWOH-UHFFFAOYSA-N 0.000 description 3
241000237502 Ostreidae Species 0.000 description 3
240000004808 Saccharomyces cerevisiae Species 0.000 description 3
235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
230000008901 benefit Effects 0.000 description 3
239000012065 filter cake Substances 0.000 description 3
235000020636 oyster Nutrition 0.000 description 3
125000000864 peroxy group Chemical group O(O*)* 0.000 description 3
239000000843 powder Substances 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
235000001674 Agaricus brunnescens Nutrition 0.000 description 2
102000004190 Enzymes Human genes 0.000 description 2
108090000790 Enzymes Proteins 0.000 description 2
240000000599 Lentinula edodes Species 0.000 description 2
239000013543 active substance Substances 0.000 description 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
235000015872 dietary supplement Nutrition 0.000 description 2
BHDAXLOEFWJKTL-UHFFFAOYSA-L dipotassium;carboxylatooxy carbonate Chemical compound [K+].[K+].[O-]C(=O)OOC([O-])=O BHDAXLOEFWJKTL-UHFFFAOYSA-L 0.000 description 2
238000001035 drying Methods 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000005516 engineering process Methods 0.000 description 2
239000000499 gel Substances 0.000 description 2
150000004676 glycans Chemical class 0.000 description 2
238000000227 grinding Methods 0.000 description 2
238000003306 harvesting Methods 0.000 description 2
230000002519 immonomodulatory effect Effects 0.000 description 2
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
230000007935 neutral effect Effects 0.000 description 2
KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 2
229920001282 polysaccharide Polymers 0.000 description 2
239000005017 polysaccharide Substances 0.000 description 2
BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
239000002994 raw material Substances 0.000 description 2
229910052708 sodium Inorganic materials 0.000 description 2
150000008498 β-D-glucosides Chemical class 0.000 description 2
OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
239000004382 Amylase Substances 0.000 description 1
102000013142 Amylases Human genes 0.000 description 1
108010065511 Amylases Proteins 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
208000035143 Bacterial infection Diseases 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
240000001080 Grifola frondosa Species 0.000 description 1
235000007710 Grifola frondosa Nutrition 0.000 description 1
206010020751 Hypersensitivity Diseases 0.000 description 1
241000681116 Laminaria sp. Species 0.000 description 1
235000001715 Lentinula edodes Nutrition 0.000 description 1
206010027476 Metastases Diseases 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
KKCBUQHMOMHUOY-UHFFFAOYSA-N Na2O Inorganic materials [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 1
244000197580 Poria cocos Species 0.000 description 1
235000008599 Poria cocos Nutrition 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
241000700605 Viruses Species 0.000 description 1
GQBMZQUFIOSOMB-UHFFFAOYSA-N [Na].C(C)(=O)OO Chemical compound [Na].C(C)(=O)OO GQBMZQUFIOSOMB-UHFFFAOYSA-N 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000007815 allergy Effects 0.000 description 1
235000019418 amylase Nutrition 0.000 description 1
230000008512 biological response Effects 0.000 description 1
230000037396 body weight Effects 0.000 description 1
150000001720 carbohydrates Chemical class 0.000 description 1
235000014633 carbohydrates Nutrition 0.000 description 1
210000004027 cell Anatomy 0.000 description 1
210000002421 cell wall Anatomy 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
238000002512 chemotherapy Methods 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
235000012000 cholesterol Nutrition 0.000 description 1
230000000295 complement effect Effects 0.000 description 1
230000006378 damage Effects 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
230000007123 defense Effects 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
VTIIJXUACCWYHX-UHFFFAOYSA-L disodium;carboxylatooxy carbonate Chemical compound [Na+].[Na+].[O-]C(=O)OOC([O-])=O VTIIJXUACCWYHX-UHFFFAOYSA-L 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000013583 drug formulation Substances 0.000 description 1
239000012636 effector Substances 0.000 description 1
238000005265 energy consumption Methods 0.000 description 1
230000002708 enhancing effect Effects 0.000 description 1
235000019253 formic acid Nutrition 0.000 description 1
235000011389 fruit/vegetable juice Nutrition 0.000 description 1
239000008103 glucose Substances 0.000 description 1
230000035876 healing Effects 0.000 description 1
229920001519 homopolymer Polymers 0.000 description 1
210000000987 immune system Anatomy 0.000 description 1
239000000367 immunologic factor Substances 0.000 description 1
229960001438 immunostimulant agent Drugs 0.000 description 1
239000003022 immunostimulating agent Substances 0.000 description 1
239000012535 impurity Substances 0.000 description 1
230000005764 inhibitory process Effects 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000007791 liquid phase Substances 0.000 description 1
229920002521 macromolecule Polymers 0.000 description 1
230000009401 metastasis Effects 0.000 description 1
238000002156 mixing Methods 0.000 description 1
239000003607 modifier Substances 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
238000011275 oncology therapy Methods 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
229910000027 potassium carbonate Inorganic materials 0.000 description 1
JWPGVOJUUSVNTL-UHFFFAOYSA-M potassium;oxido formate Chemical compound [K+].[O-]OC=O JWPGVOJUUSVNTL-UHFFFAOYSA-M 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000001959 radiotherapy Methods 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
238000007670 refining Methods 0.000 description 1
208000017520 skin disease Diseases 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
229940045872 sodium percarbonate Drugs 0.000 description 1
SPDUKHLMYVCLOA-UHFFFAOYSA-M sodium;ethaneperoxoate Chemical compound [Na+].CC(=O)O[O-] SPDUKHLMYVCLOA-UHFFFAOYSA-M 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000000758 substrate Substances 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
230000003612 virological effect Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Materials Engineering (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Organic Chemistry (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SK85-2012A 2012-10-26 2012-10-26 Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu SK852012A3 (sk)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
SK85-2012A SK852012A3 (sk)	2012-10-26	2012-10-26	Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu
ATGM8023/2015U AT14719U1 (de)	2012-10-26	2013-05-27	Gewinnung von hochsauberem beta-1,3/1,6-D-Glukan
ATA433/2013A AT513524A1 (de)	2012-10-26	2013-05-27	Gewinnung von hochsauberem beta-1,3/1, 6-D-Glukan

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SK85-2012A SK852012A3 (sk)	2012-10-26	2012-10-26	Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu

Publications (1)

Publication Number	Publication Date
SK852012A3 true SK852012A3 (sk)	2014-06-03

Family

ID=50686276

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK85-2012A SK852012A3 (sk)	2012-10-26	2012-10-26	Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu

Country Status (2)

Country	Link
AT (2)	AT14719U1 (de)
SK (1)	SK852012A3 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CS63090A2 (en) *	1991-12-16	1991-12-17	Univ Slovenska Tech	method of fungal glucan insulation
SK282870B6 (sk) *	2001-04-23	2003-01-09	Pleuran, S. R. O.	Spôsob izolácie imunostimulačného glukánu z hlivy ustricovej
SK288404B6 (sk) *	2009-07-13	2016-10-03	Tibor Doboly	Spôsob získavania vysokočistého beta-1,3/1,6-D-glukánu
CZ305050B6 (cs) *	2009-07-22	2015-04-15	Jihočeská univerzita v Českých Budějovicích, Zemědělská fakulta	Způsob výroby surového β-glukanu z plodnic houby hlívy ústřičné (Pleurotus ostreatus) nebo ze substrátu pro pěstování hlívy ústřičné

2012
- 2012-10-26 SK SK85-2012A patent/SK852012A3/sk not_active Application Discontinuation
2013
- 2013-05-27 AT ATGM8023/2015U patent/AT14719U1/de not_active IP Right Cessation
- 2013-05-27 AT ATA433/2013A patent/AT513524A1/de active IP Right Grant

Also Published As

Publication number	Publication date
AT14719U1 (de)	2016-04-15
AT513524A1 (de)	2014-05-15

Legal Events

Date	Code	Title	Description
2016-04-01	FC9A	Refused patent application

Publication	Publication Date	Title
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