SK9682000A3 - Novel polyethoxylated castor oil, process of making the same and formulations thereof - Google Patents

Novel polyethoxylated castor oil, process of making the same and formulations thereof Download PDF

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Publication number
SK9682000A3
SK9682000A3 SK968-2000A SK9682000A SK9682000A3 SK 9682000 A3 SK9682000 A3 SK 9682000A3 SK 9682000 A SK9682000 A SK 9682000A SK 9682000 A3 SK9682000 A3 SK 9682000A3
Authority
SK
Slovakia
Prior art keywords
castor oil
polyethoxylated castor
polyethoxylated
formulation
cation
Prior art date
Application number
SK968-2000A
Other languages
English (en)
Slovak (sk)
Inventor
Alexandr Nikolayev
Sayeed Fakrul
Rupa IYAR
Mitchell Garber
Robert C Butterhof
Todd M Hoyer
Marvin Samson
Original Assignee
Schein Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schein Pharmaceutical Inc filed Critical Schein Pharmaceutical Inc
Publication of SK9682000A3 publication Critical patent/SK9682000A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/43Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/56Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
SK968-2000A 1997-12-24 1998-04-28 Novel polyethoxylated castor oil, process of making the same and formulations thereof SK9682000A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/998,306 US5925776A (en) 1997-12-24 1997-12-24 Polyethoxylated castor oil, process of making the same and formulations thereof
PCT/US1998/008521 WO1999033780A1 (en) 1997-12-24 1998-04-28 Novel polyethoxylated castor oil, process of making the same and formulations thereof

Publications (1)

Publication Number Publication Date
SK9682000A3 true SK9682000A3 (en) 2000-12-11

Family

ID=25545031

Family Applications (1)

Application Number Title Priority Date Filing Date
SK968-2000A SK9682000A3 (en) 1997-12-24 1998-04-28 Novel polyethoxylated castor oil, process of making the same and formulations thereof

Country Status (14)

Country Link
US (1) US5925776A (no)
EP (1) EP1045825A1 (no)
JP (1) JP2003518140A (no)
KR (1) KR20010033607A (no)
AU (1) AU7261798A (no)
BG (1) BG104555A (no)
CA (1) CA2315853A1 (no)
EA (1) EA200000569A1 (no)
HU (1) HUP0100211A2 (no)
IL (1) IL136942A0 (no)
NO (1) NO20003206L (no)
PL (1) PL341757A1 (no)
SK (1) SK9682000A3 (no)
WO (1) WO1999033780A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100330373B1 (ko) * 1996-05-28 2002-11-07 주식회사한국신약 탁솔을 함유한 주사용 약제 조성물
KR19990075621A (ko) * 1998-03-23 1999-10-15 임성주 경사 평판형 배양조
US6388112B1 (en) 1998-10-20 2002-05-14 Ben Venue Laboratories, Inc. Process for purification of solvents useful in the preparation of pharmaceutical compositions
US6828346B2 (en) * 1999-10-25 2004-12-07 Supergen, Inc. Methods for administration of paclitaxel
US6136846A (en) 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
JP2003520230A (ja) * 2000-01-20 2003-07-02 ベーカー ノートン ファーマシューティカルズ インコーポレイテッド 活性炭を用いたポリオキシエチル化ヒマシ油の精製およびこれの医薬組成物
US6919370B2 (en) * 2000-11-28 2005-07-19 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
WO2002058689A1 (en) 2000-12-05 2002-08-01 Childrens Hospital Los Angeles Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same
AU2002351169B2 (en) * 2001-11-26 2007-09-20 Intas Pharmaceuticals Limited Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions
AU2002357012A1 (en) * 2001-11-27 2003-06-10 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
CZ294371B6 (cs) * 2002-06-10 2004-12-15 Pliva - Lachema, A. S. Stabilizovaná farmaceutická kompozice na bázi polyoxyethylovaného ricinového oleje a způsob její přípravy
WO2004100994A2 (de) * 2003-05-19 2004-11-25 Ebewe Pharma Ges.M.B.H. Nfg.Kg Werfahren zur herstellung einer stabilen injizierbaren formulierung von schwer löslichen antineoplastischen wirkstoffen
US20050016926A1 (en) * 2003-07-24 2005-01-27 Dabur Research Foundation Stabilized formulation
US20050256097A1 (en) * 2004-05-11 2005-11-17 Kosan Biosciences, Inc. Pharmaceutical solution formulations containing 17-AAG
JP2009511643A (ja) * 2005-06-21 2009-03-19 ザ・コカ−コーラ・カンパニー エッセンシャル・オイルから汚染物質を除去するための方法
CA2880727C (en) 2005-08-31 2019-05-07 Neil P. Desai Compositions comprising poorly water soluble pharmaceutical agents and antimicrobial agents
CA2642324C (en) * 2006-02-21 2011-03-29 Dabur Pharma Limited Stable pharmaceutical composition of taxanes
EP2777691A1 (en) * 2013-03-14 2014-09-17 Pharmachemie B.V. Taxoid - Purification of Liquid Excipients
CN112778513A (zh) * 2020-12-30 2021-05-11 江苏优仿医药科技有限公司 一种聚氧乙烯蓖麻油的精制方法及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
US5407683A (en) * 1990-06-01 1995-04-18 Research Corporation Technologies, Inc. Pharmaceutical solutions and emulsions containing taxol
FR2698543B1 (fr) * 1992-12-02 1994-12-30 Rhone Poulenc Rorer Sa Nouvelles compositions à base de taxoides.
TW406020B (en) * 1993-09-29 2000-09-21 Bristol Myers Squibb Co Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
US5415869A (en) * 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
US5462726A (en) * 1993-12-17 1995-10-31 Bristol-Myers Squibb Company Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents
US5681846A (en) * 1995-03-17 1997-10-28 Board Of Regents, The University Of Texas System Extended stability formulations for paclitaxel

Also Published As

Publication number Publication date
AU7261798A (en) 1999-07-19
EP1045825A1 (en) 2000-10-25
BG104555A (en) 2001-08-31
PL341757A1 (en) 2001-05-07
IL136942A0 (en) 2001-06-14
HUP0100211A2 (hu) 2001-06-28
WO1999033780A1 (en) 1999-07-08
CA2315853A1 (en) 1999-07-08
US5925776A (en) 1999-07-20
NO20003206L (no) 2000-08-22
EA200000569A1 (ru) 2001-04-23
NO20003206D0 (no) 2000-06-21
KR20010033607A (ko) 2001-04-25
JP2003518140A (ja) 2003-06-03

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