SMAP201000112A - Derivati di imidazo[1,2-B]piridazina per il trattamento di una malattia mediata da tirosina chinasi c-met. - Google Patents

Derivati di imidazo[1,2-B]piridazina per il trattamento di una malattia mediata da tirosina chinasi c-met.

Info

Publication number
SMAP201000112A
SMAP201000112A SM201000112T SM201000112T SMAP201000112A SM AP201000112 A SMAP201000112 A SM AP201000112A SM 201000112 T SM201000112 T SM 201000112T SM 201000112 T SM201000112 T SM 201000112T SM AP201000112 A SMAP201000112 A SM AP201000112A
Authority
SM
San Marino
Prior art keywords
pyridazine
treatment
tyrosine kinase
mediated disease
met tyrosine
Prior art date
Application number
SM201000112T
Other languages
English (en)
Inventor
Frederic Stauffer
Pascal Furet
Clive Mccarthy
Joseph Schoepfer
Carsten Spanka
Melanie Stang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39672115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMAP201000112(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SMAP201000112A publication Critical patent/SMAP201000112A/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SM201000112T 2008-02-28 2010-09-28 Derivati di imidazo[1,2-B]piridazina per il trattamento di una malattia mediata da tirosina chinasi c-met. SMAP201000112A (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08152068 2008-02-28
PCT/EP2009/052302 WO2009106577A1 (en) 2008-02-28 2009-02-26 Imidazo [1,2-b] pyridazine derivatives for the treatment of c-met tyrosine kinase mediated disease

Publications (1)

Publication Number Publication Date
SMAP201000112A true SMAP201000112A (it) 2010-11-12

Family

ID=39672115

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201000112T SMAP201000112A (it) 2008-02-28 2010-09-28 Derivati di imidazo[1,2-B]piridazina per il trattamento di una malattia mediata da tirosina chinasi c-met.

Country Status (25)

Country Link
US (1) US8822468B2 (it)
EP (1) EP2265614A1 (it)
JP (1) JP5576802B2 (it)
KR (1) KR20100128305A (it)
CN (1) CN102015716B (it)
AR (1) AR070487A1 (it)
AU (1) AU2009218459A1 (it)
BR (1) BRPI0908504A2 (it)
CA (1) CA2717034A1 (it)
CL (1) CL2009000443A1 (it)
CO (1) CO6300957A2 (it)
CR (1) CR11620A (it)
DO (1) DOP2010000263A (it)
EA (1) EA201001365A1 (it)
EC (1) ECSP10010427A (it)
IL (1) IL207434A0 (it)
MA (1) MA32167B1 (it)
MX (1) MX2010009414A (it)
NI (1) NI201000145A (it)
PE (1) PE20091468A1 (it)
SM (1) SMAP201000112A (it)
TW (1) TW200940545A (it)
UY (1) UY31676A1 (it)
WO (1) WO2009106577A1 (it)
ZA (1) ZA201005602B (it)

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US8637516B2 (en) * 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
HK1197063A1 (en) * 2011-06-22 2015-01-02 拜耳知识产权有限责任公司 Heterocyclyl aminoimidazopyridazines
CN103958509B (zh) * 2011-09-15 2015-12-23 诺华股份有限公司 作为酪氨酸激酶抑制剂的6-取代的3-(喹啉-6-基硫代)-[1,2,4]三唑并[4,3-a]吡啶化合物
UY34329A (es) 2011-09-15 2013-04-30 Novartis Ag Compuestos de triazolopiridina
CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
SI2925757T1 (en) 2012-11-19 2018-01-31 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
US9370515B2 (en) 2013-03-07 2016-06-21 Califia Bio, Inc. Mixed lineage kinase inhibitors and method of treatments
AR097543A1 (es) * 2013-09-06 2016-03-23 Lexicon Pharmaceuticals Inc COMPUESTOS BASADOS EN IMIDAZO[1,2-b]PIRIDAZINA, COMPOSICIONES QUE LOS COMPRENDEN Y SUS MÉTODOS DE USO
CN105326793A (zh) * 2014-08-06 2016-02-17 中美冠科生物技术（太仓）有限公司 一种包含c-Met激酶抑制剂的固体分散体及其制备方法和用途
HUE045220T2 (hu) * 2014-12-19 2019-12-30 Janssen Pharmaceutica Nv Imidazopiridazin-származékok mint PI3Kbéta inhibitorok
MX2017008076A (es) * 2014-12-19 2018-01-09 Janssen Pharmaceutica Nv DERIVADOS DE IMIDAZOPIRIDAZINA ENLAZADOS A HETEROCICLILO COMO INHIBIDORES DE PI3Kß.
CN109715631B (zh) * 2016-09-16 2022-02-18 德国亥姆霍兹慕尼黑中心健康与环境研究中心（有限公司） Traf 6抑制剂
WO2018115319A2 (en) * 2016-12-23 2018-06-28 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Inhibitors of cytochrome p450 family 7 subfamily b member 1 (cyp7b1) for use in treating diseases
WO2018138050A1 (de) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel
WO2018237349A1 (en) * 2017-06-23 2018-12-27 University Of Washington Inhibitors of typed 1 methionyl-trna synthetase and methods of using them
JP7296992B2 (ja) * 2018-05-28 2023-06-23 エフ． ホフマン－ラ ロシュ アーゲー 細菌感染症の処置および予防のための新規オキソキノリジン化合物
US20230059009A1 (en) * 2019-12-18 2023-02-23 The Regents Of The University Of California Inhibitors of lin28 and methods of use thereof
CN119081395B (zh) * 2024-09-07 2025-03-18 广东环塑众创实业有限公司 一种耐高温尼龙工程塑料及其制备方法

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Also Published As

Publication number Publication date
CL2009000443A1 (es) 2010-09-10
DOP2010000263A (es) 2010-09-30
KR20100128305A (ko) 2010-12-07
CN102015716A (zh) 2011-04-13
WO2009106577A1 (en) 2009-09-03
PE20091468A1 (es) 2009-10-22
CR11620A (es) 2010-10-08
AR070487A1 (es) 2010-04-07
ECSP10010427A (es) 2010-09-30
CN102015716B (zh) 2014-09-17
EA201001365A1 (ru) 2011-04-29
AU2009218459A1 (en) 2009-09-03
JP2011513279A (ja) 2011-04-28
UY31676A1 (es) 2009-09-30
US8822468B2 (en) 2014-09-02
IL207434A0 (en) 2010-12-30
BRPI0908504A2 (pt) 2015-08-11
EP2265614A1 (en) 2010-12-29
US20090264406A1 (en) 2009-10-22
MX2010009414A (es) 2010-09-24
ZA201005602B (en) 2011-04-28
MA32167B1 (fr) 2011-03-01
NI201000145A (es) 2011-03-02
CO6300957A2 (es) 2011-07-21
TW200940545A (en) 2009-10-01
CA2717034A1 (en) 2009-09-03
JP5576802B2 (ja) 2014-08-20

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