SMT202000213T1 - Modulatori dell'attivita' del complemento - Google Patents

Modulatori dell'attivita' del complemento

Info

Publication number
SMT202000213T1
SMT202000213T1 SM20200213T SMT202000213T SMT202000213T1 SM T202000213 T1 SMT202000213 T1 SM T202000213T1 SM 20200213 T SM20200213 T SM 20200213T SM T202000213 T SMT202000213 T SM T202000213T SM T202000213 T1 SMT202000213 T1 SM T202000213T1
Authority
SM
San Marino
Prior art keywords
modulators
complement activity
complement
activity
Prior art date
Application number
SM20200213T
Other languages
English (en)
Inventor
Michelle Denise Hoarty
Alonso Ricardo
Douglas A Treco
Steven James Demarco
Grace Victoria Parker
Sylvia Tobe
Original Assignee
Ra Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ra Pharmaceuticals Inc filed Critical Ra Pharmaceuticals Inc
Publication of SMT202000213T1 publication Critical patent/SMT202000213T1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Steroid Compounds (AREA)
  • Amplifiers (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SM20200213T 2015-12-16 2016-12-07 Modulatori dell'attivita' del complemento SMT202000213T1 (it)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562268360P 2015-12-16 2015-12-16
US201662331320P 2016-05-03 2016-05-03
US201662347486P 2016-06-08 2016-06-08
EP16823378.1A EP3389692B1 (en) 2015-12-16 2016-12-07 Modulators of complement activity
PCT/US2016/065228 WO2017105939A1 (en) 2015-12-16 2016-12-07 Modulators of complement activity

Publications (1)

Publication Number Publication Date
SMT202000213T1 true SMT202000213T1 (it) 2020-05-08

Family

ID=57758701

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20200213T SMT202000213T1 (it) 2015-12-16 2016-12-07 Modulatori dell'attivita' del complemento

Country Status (24)

Country Link
US (3) US10835574B2 (it)
EP (4) EP4218790B1 (it)
JP (2) JP7126940B2 (it)
CN (2) CN108697759B (it)
AU (1) AU2016370210A1 (it)
CA (1) CA3007772A1 (it)
CY (2) CY1123031T1 (it)
DK (2) DK3685847T5 (it)
ES (3) ES2941640T3 (it)
FI (1) FI3685847T3 (it)
HR (3) HRP20200508T1 (it)
HU (1) HUE061759T2 (it)
IL (1) IL259762B (it)
LT (2) LT3389692T (it)
MX (2) MX2018007352A (it)
PL (2) PL3685847T3 (it)
PT (2) PT3389692T (it)
RS (2) RS64067B1 (it)
RU (2) RU2769701C2 (it)
SG (1) SG11201804721SA (it)
SI (2) SI3685847T1 (it)
SM (1) SMT202000213T1 (it)
TW (2) TWI745320B (it)
WO (1) WO2017105939A1 (it)

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* Cited by examiner, † Cited by third party
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HUE045646T2 (hu) 2014-06-12 2020-01-28 Ra Pharmaceuticals Inc Komplement aktivitás modulálása
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CA3045114A1 (en) 2016-12-07 2018-06-14 Ra Pharmaceuticals, Inc. Modulators of complement activity
KR20200095485A (ko) 2017-12-04 2020-08-10 라 파마슈티컬스 인코포레이티드 보체 활성의 조절인자
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EP3934675A2 (en) 2019-03-08 2022-01-12 RA Pharmaceuticals, Inc. Zilucoplan as deep tissue penetrating c5 inhibitor
CA3137895A1 (en) * 2019-04-24 2020-10-29 Ra Pharmaceuticals, Inc. Compositions and methods for modulating complement activity
US12558398B2 (en) 2019-06-04 2026-02-24 Ucb Holdings, Inc. Inflammatory disease treatment with complement inhibitors
US20220370548A1 (en) * 2019-09-12 2022-11-24 Ra Pharmaceuticals, Inc. Neurological disease treatment with complement inhibitors
EP4142738A1 (en) 2020-04-30 2023-03-08 Alnylam Pharmaceuticals, Inc. Complement factor b (cfb) irna compositions and methods of use thereof
CN116194478A (zh) 2020-06-24 2023-05-30 阿雷克森制药公司 皮下(sc)施用抗c5抗体治疗补体相关病症
CA3234636A1 (en) 2021-10-29 2023-05-04 Alnylam Pharmaceuticals, Inc. Complement factor b (cfb) irna compositions and methods of use thereof

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Also Published As

Publication number Publication date
LT3389692T (lt) 2020-04-27
HRP20200508T1 (hr) 2020-09-04
ES2941640T3 (es) 2023-05-24
RS64067B1 (sr) 2023-04-28
RU2018121615A (ru) 2020-01-20
RU2020131790A3 (it) 2021-11-18
EP3389692A1 (en) 2018-10-24
EP3389692B1 (en) 2020-03-04
FI3685847T3 (fi) 2023-04-03
US20250090624A1 (en) 2025-03-20
MX2022013454A (es) 2023-02-22
PL3685847T3 (pl) 2023-05-08
IL259762A (en) 2018-07-31
HRP20230182T1 (hr) 2023-04-14
TWI745320B (zh) 2021-11-11
HRP20260470T1 (hr) 2026-05-08
PT3389692T (pt) 2020-04-07
AU2016370210A1 (en) 2018-06-21
CA3007772A1 (en) 2017-06-22
US20210077572A1 (en) 2021-03-18
LT3685847T (lt) 2023-03-27
JP2022159479A (ja) 2022-10-17
WO2017105939A1 (en) 2017-06-22
CY1123031T1 (el) 2021-10-29
SI3685847T1 (sl) 2023-05-31
CN108697759B (zh) 2022-08-02
ES2781551T3 (es) 2020-09-03
CN108697759A (zh) 2018-10-23
CN115920000B (zh) 2025-04-25
MX2018007352A (es) 2019-05-16
EP3685847B1 (en) 2023-01-11
DK3389692T3 (da) 2020-03-30
CN115920000A (zh) 2023-04-07
HUE061759T2 (hu) 2023-08-28
RU2018121615A3 (it) 2020-03-16
TW202200189A (zh) 2022-01-01
DK3685847T5 (da) 2024-08-26
US10835574B2 (en) 2020-11-17
EP3685847A1 (en) 2020-07-29
TWI779805B (zh) 2022-10-01
PL3389692T3 (pl) 2020-06-15
KR20180094913A (ko) 2018-08-24
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JP7379615B2 (ja) 2023-11-14
EP4218790C0 (en) 2026-02-18
DK3685847T3 (da) 2023-02-27
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TW201733609A (zh) 2017-10-01
RU2733720C2 (ru) 2020-10-06
US20180369322A1 (en) 2018-12-27
JP2019504012A (ja) 2019-02-14
PT3685847T (pt) 2023-03-14
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SG11201804721SA (en) 2018-07-30
RS60134B1 (sr) 2020-05-29
EP4729094A2 (en) 2026-04-22
RU2020131790A (ru) 2020-10-20
EP4218790A1 (en) 2023-08-02
IL259762B (en) 2020-06-30
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ES3066593T3 (en) 2026-05-13
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BR112018012174A2 (pt) 2018-12-04
RU2769701C2 (ru) 2022-04-05

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