SMT202000435T1 - Combinazione di agonisti inversi di recettore di istamina-3 con inibitori di acetilcolinesterasi - Google Patents
Combinazione di agonisti inversi di recettore di istamina-3 con inibitori di acetilcolinesterasiInfo
- Publication number
- SMT202000435T1 SMT202000435T1 SM20200435T SMT202000435T SMT202000435T1 SM T202000435 T1 SMT202000435 T1 SM T202000435T1 SM 20200435 T SM20200435 T SM 20200435T SM T202000435 T SMT202000435 T SM T202000435T SM T202000435 T1 SMT202000435 T1 SM T202000435T1
- Authority
- SM
- San Marino
- Prior art keywords
- histamine
- combination
- inverse agonists
- acetylcholinesterase inhibitors
- receptor inverse
- Prior art date
Links
- 239000000544 cholinesterase inhibitor Substances 0.000 title 1
- 239000002469 receptor inverse agonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201641028166 | 2016-08-18 | ||
| PCT/IB2017/054938 WO2018033847A1 (en) | 2016-08-18 | 2017-08-14 | Combination of histamine-3 receptor inverse agonists with acetylcholinesterase inhibitors |
| EP17768234.1A EP3500253B1 (en) | 2016-08-18 | 2017-08-14 | Combination of histamine-3 receptor inverse agonists with acetylcholinesterase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202000435T1 true SMT202000435T1 (it) | 2020-09-10 |
Family
ID=59887325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20200435T SMT202000435T1 (it) | 2016-08-18 | 2017-08-14 | Combinazione di agonisti inversi di recettore di istamina-3 con inibitori di acetilcolinesterasi |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US10603323B2 (it) |
| EP (1) | EP3500253B1 (it) |
| JP (1) | JP6734470B2 (it) |
| KR (1) | KR102039585B1 (it) |
| CN (1) | CN109640975B (it) |
| AU (1) | AU2017313427B2 (it) |
| CA (1) | CA3033039C (it) |
| CY (1) | CY1123238T1 (it) |
| DK (1) | DK3500253T3 (it) |
| EA (1) | EA032957B1 (it) |
| ES (1) | ES2810983T3 (it) |
| HR (1) | HRP20201262T1 (it) |
| HU (1) | HUE052003T2 (it) |
| IL (1) | IL264406B (it) |
| LT (1) | LT3500253T (it) |
| MA (1) | MA45990B1 (it) |
| MD (1) | MD3500253T2 (it) |
| ME (1) | ME03812B (it) |
| MX (1) | MX374114B (it) |
| NZ (1) | NZ750150A (it) |
| PL (1) | PL3500253T3 (it) |
| PT (1) | PT3500253T (it) |
| RS (1) | RS60669B1 (it) |
| SG (1) | SG11201900681SA (it) |
| SI (1) | SI3500253T1 (it) |
| SM (1) | SMT202000435T1 (it) |
| WO (1) | WO2018033847A1 (it) |
| ZA (1) | ZA201900467B (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3806859T (lt) * | 2018-05-31 | 2025-03-25 | Suven Life Sciences Limited | Gydymo histamino-3 receptorių atvirkštiniu agonistu būdas |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20120035183A (ko) * | 2009-06-10 | 2012-04-13 | 선오비온 파마슈티컬스 인코포레이티드 | 히스타민 ｈ3 역 작용제 및 길항제, 및 이의 사용 방법 |
| EA023260B1 (ru) * | 2011-02-23 | 2016-05-31 | Сувен Лайф Сайенсиз Лимитед | Новые соединения в качестве лигандов гистаминовых h-рецепторов |
| FR2974729B1 (fr) | 2011-05-02 | 2013-04-19 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide et un inhibiteur de l'acetylcholinesterase et les compositions pharmaceutiques qui la contiennent |
| HUP1300139A2 (en) * | 2013-03-06 | 2014-09-29 | Richter Gedeon Nyrt | Phenoxypiperidine h3 antagonists |
| EP3043799A1 (en) | 2013-09-09 | 2016-07-20 | Sanofi | An h3 receptor antagonist combined with a cholinesterase inhibitor for use in the treatment of alzheimer's disease |
-
2017
- 2017-08-14 AU AU2017313427A patent/AU2017313427B2/en active Active
- 2017-08-14 NZ NZ750150A patent/NZ750150A/en unknown
- 2017-08-14 ME MEP-2020-167A patent/ME03812B/me unknown
- 2017-08-14 PT PT177682341T patent/PT3500253T/pt unknown
- 2017-08-14 LT LTEP17768234.1T patent/LT3500253T/lt unknown
- 2017-08-14 ES ES17768234T patent/ES2810983T3/es active Active
- 2017-08-14 HU HUE17768234A patent/HUE052003T2/hu unknown
- 2017-08-14 CA CA3033039A patent/CA3033039C/en active Active
- 2017-08-14 RS RS20200949A patent/RS60669B1/sr unknown
- 2017-08-14 SI SI201730360T patent/SI3500253T1/sl unknown
- 2017-08-14 MA MA45990A patent/MA45990B1/fr unknown
- 2017-08-14 MX MX2019001696A patent/MX374114B/es active IP Right Grant
- 2017-08-14 SG SG11201900681SA patent/SG11201900681SA/en unknown
- 2017-08-14 WO PCT/IB2017/054938 patent/WO2018033847A1/en not_active Ceased
- 2017-08-14 HR HRP20201262TT patent/HRP20201262T1/hr unknown
- 2017-08-14 US US16/320,949 patent/US10603323B2/en active Active
- 2017-08-14 JP JP2019506640A patent/JP6734470B2/ja active Active
- 2017-08-14 SM SM20200435T patent/SMT202000435T1/it unknown
- 2017-08-14 KR KR1020197007056A patent/KR102039585B1/ko active Active
- 2017-08-14 EA EA201990480A patent/EA032957B1/ru unknown
- 2017-08-14 EP EP17768234.1A patent/EP3500253B1/en active Active
- 2017-08-14 DK DK17768234.1T patent/DK3500253T3/da active
- 2017-08-14 PL PL17768234T patent/PL3500253T3/pl unknown
- 2017-08-14 CN CN201780049311.9A patent/CN109640975B/zh active Active
- 2017-08-14 MD MDE20190714T patent/MD3500253T2/ro unknown
-
2019
- 2019-01-22 IL IL264406A patent/IL264406B/en active IP Right Grant
- 2019-01-23 ZA ZA2019/00467A patent/ZA201900467B/en unknown
-
2020
- 2020-08-05 CY CY20201100725T patent/CY1123238T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL288519B1 (en) | inhibitors of ret | |
| ZA201801750B (en) | Farnesoid x receptor agonists and uses thereof | |
| PL3099720T3 (pl) | Zastosowanie dodatków opartych na kwasach polikarboksylowych do paliw silnikowych | |
| IL279949A (en) | Heterocyclic MCT4 inhibitors | |
| IL284005A (en) | Glucocorticoid receptor inhibitors | |
| EP3405477C0 (en) | TRANSGLUTAMINASE INHIBITORS | |
| IL264628A (en) | Combination of fxr agonists | |
| IL262921B (en) | Combination of pure 5-HT6 receptor antagonists with acetylcholinesterase inhibitors | |
| GB201417529D0 (en) | Beta lactamase inhibitors | |
| AU2017313427B2 (en) | Combination of histamine-3 receptor inverse agonists with acetylcholinesterase inhibitors | |
| IL264405B (en) | Triple combination of histamine-3 receptor inverse agonists, acetylcholinesterase inhibitors and nmda receptor antagonist | |
| PL3529338T3 (pl) | Kombinacja dodatków do paliwa | |
| IL258573A (en) | Inhibitor of the p2x7 receptor | |
| GB201621528D0 (en) | Use of trpv1 agonist |