SMT202000522T1 - Composizioni farmaceutiche per uso topico a base di acido ialuronico solfatato come promotore dell'assorbimento cutaneo - Google Patents

Composizioni farmaceutiche per uso topico a base di acido ialuronico solfatato come promotore dell'assorbimento cutaneo

Info

Publication number: SMT202000522T1
Authority: SM; San Marino
Prior art keywords: pharmaceutical compositions; hyaluronic acid; use based; topical use; skin absorption
Prior art date: 2009-05-14

Application number

SM20200522T

Other languages

English (en)

Inventor

Giovanni Gennari

Matteo D'este

Original Assignee

Fidia Farm Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-05-14

Filing date

2010-05-14

Publication date

2020-11-10

2010-05-14 Application filed by Fidia Farm Spa filed Critical Fidia Farm Spa

2020-11-10 Publication of SMT202000522T1 publication Critical patent/SMT202000522T1/it

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
229940124532 absorption promoter Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
230000037384 skin absorption Effects 0.000 title 1
231100000274 skin absorption Toxicity 0.000 title 1
230000000699 topical effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
- A61Q1/06—Lipsticks
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01035—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Dermatology (AREA)
Virology (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Biochemistry (AREA)
Birds (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oral & Maxillofacial Surgery (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Polymers & Plastics (AREA)
Materials Engineering (AREA)
Diabetes (AREA)
Hematology (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)

SM20200522T 2009-05-14 2010-05-14 Composizioni farmaceutiche per uso topico a base di acido ialuronico solfatato come promotore dell'assorbimento cutaneo SMT202000522T1 (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITPD2009A000134A IT1397246B1 (it)	2009-05-14	2009-05-14	Nuovi medicamenti ad uso topico a base di acido ialuronico solfatato come agente attivante o inibente l'attivita' citochinica
EP18185228.6A EP3417855B1 (en)	2009-05-14	2010-05-14	Pharmaceutical compositions for topical use based on sulfated hyaluronic acid as skin absorption promoter

Publications (1)

Publication Number	Publication Date
SMT202000522T1 true SMT202000522T1 (it)	2020-11-10

Family

ID=41226841

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SM20190015T SMT201900015T1 (it)	2009-05-14	2010-05-14	Medicamento per uso topico a base di acido ialuronico solfatato per il trattamento dei coaguli di fibrina e dei trombi
SM20200522T SMT202000522T1 (it)	2009-05-14	2010-05-14	Composizioni farmaceutiche per uso topico a base di acido ialuronico solfatato come promotore dell'assorbimento cutaneo
SM201600455T SMT201600455B (it)	2009-05-14	2016-12-14	Nuovi medicamenti ad uso topico a base di acido ialuronico solfatato come agente attivante o inibente l'attività citochinica

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SM20190015T SMT201900015T1 (it)	2009-05-14	2010-05-14	Medicamento per uso topico a base di acido ialuronico solfatato per il trattamento dei coaguli di fibrina e dei trombi

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SM201600455T SMT201600455B (it)	2009-05-14	2016-12-14	Nuovi medicamenti ad uso topico a base di acido ialuronico solfatato come agente attivante o inibente l'attività citochinica

Country Status (15)

Country	Link
US (4)	US20120121572A1 (it)
EP (3)	EP3417855B1 (it)
CN (1)	CN102427808B (it)
CA (2)	CA2995610C (it)
ES (3)	ES2704921T3 (it)
HR (1)	HRP20161574T1 (it)
HU (1)	HUE030673T2 (it)
IT (1)	IT1397246B1 (it)
LT (1)	LT2429515T (it)
PL (1)	PL2429515T3 (it)
PT (1)	PT2429515T (it)
RU (3)	RU2543354C2 (it)
SI (1)	SI2429515T1 (it)
SM (3)	SMT201900015T1 (it)
WO (1)	WO2010130468A1 (it)

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US8343942B2 (en) *	2008-04-04	2013-01-01	University Of Utah Research Foundation	Methods for treating interstitial cystitis
JP5758797B2 (ja)	2008-04-04	2015-08-05	ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション	アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法
IT1397247B1 (it) *	2009-05-14	2013-01-04	Fidia Farmaceutici	Nuovi agenti regolatori dell'attivita' citochinica
US20130209531A1 (en)	2010-06-08	2013-08-15	University Of Utah Research Foundation	Applications of partially and fully sulfated hyaluronan
CA2830933A1 (en)	2011-03-23	2012-09-27	University Of Utah Research Foundation	Methods for treating or preventing urological inflammation
ES2991296T3 (es)	2014-10-17	2024-12-03	Fidia Farm Spa	Sistema terapéutico dérmico de alta adhesividad
ITUB20155623A1 (it) *	2015-11-16	2017-05-16	Fidia Farm Spa	Processo migliorato per la produzione di HA solfatato di elevata purezza
US11576925B2 (en) *	2016-04-25	2023-02-14	Mizhou Hui	Application of low-molecular-weight hyaluronic acid (LMW-HA) fragments
WO2018053111A1 (en)	2016-09-15	2018-03-22	University Of Utah Research Foundation	In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
IT201600117042A1 (it) *	2016-11-18	2018-05-18	Fidia Farm Spa	Acidi ialuronici solfatati funzionalizzati con dopamina
CN111228653A (zh)	2018-11-13	2020-06-05	格莱科米拉治疗公司	用电离辐射加强癌症治疗的方法
IT201900003887A1 (it)	2019-03-18	2020-09-18	Fidia Farm Spa	Sistemi di stabilizzazione e di rilascio controllato di farmaci instabili alla sterilizzazione
WO2021133000A1 (ko) *	2019-12-23	2021-07-01	주식회사 엘지화학	항염 또는 항혈관신생용 약제학적 조성물
KR20240125432A (ko) *	2020-09-29	2024-08-19	지로파, 인코포레이티드	통증 완화 및 마취를 위한 조성물 및 방법
CN113754795B (zh) *	2021-10-19	2023-03-10	澳门大学	磺酸化透明质酸类化合物、其制备方法及其应用
US20260232768A1 (en) *	2023-02-09	2026-08-13	Yanhui Xie	Treatment of atopic dermatitis with polyethylene glycol-modified interleukin 2, glucocorticoid and hyaluronic acid

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US4303676A (en) *	1980-03-21	1981-12-01	Balazs Endre A	Hyaluronate based compositions and cosmetic formulations containing same
US5639738A (en) *	1992-02-20	1997-06-17	Hyal Pharmaceutical Corporation	Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs
ITPD940054A1 (it) *	1994-03-23	1995-09-23	Fidia Advanced Biopolymers Srl	Polisaccaridi solfatati
DE69621528T2 (de)	1995-02-07	2003-01-16	Shiseido Co. Ltd., Tokio/Tokyo	Anti-inflamatorische agenzien
GB2317182B (en) *	1996-09-11	2000-11-01	Johnson & Johnson Medical	Sulfated polysaccharides and uses thereof in medical treatment
JPH10195107A (ja) *	1997-01-10	1998-07-28	Shiseido Co Ltd	オリゴ硫酸化ヒアルロン酸
ATE229038T1 (de)	1997-04-04	2002-12-15	Fidia Advanced Biopolymers Srl	N-sulfatierte hyaluronsäureverbindungen, ihre derivate und verfahren zu ihrer herstellung
DE19813234A1 (de) *	1998-03-26	1999-09-30	Knoell Hans Forschung Ev	Verfahren zur Herstellung hochsulfatierter Hyaluronsäuren
JPH11279042A (ja)	1998-03-30	1999-10-12	Shiseido Co Ltd	皮膚外用剤
CN1116044C (zh) *	1998-06-24	2003-07-30	凌沛学	含有透明质酸钠的防粘连颗粒剂和粉雾剂及其制作方法
JP2000178196A (ja) *	1998-12-11	2000-06-27	Seikagaku Kogyo Co Ltd	新規ヒアルロニダーゼ阻害剤及び外用剤
DE59906392D1 (de) *	1998-12-23	2003-08-28	Esparma Gmbh	Hyaluronatlyase als penetrationsförderer in topischen mitteln
WO2000069917A1 (fr) *	1999-05-18	2000-11-23	Maruho Kabushikikaisha	Compositions medicinales destinees a inhiber le systeme kallikreine-kinine ou la phospholipase a¿2?
JP2001163789A (ja) *	1999-12-13	2001-06-19	Maruho Co Ltd	マトリックスメタロプロテアーゼ阻害用医薬組成物
AU2001242315A1 (en) *	2000-03-21	2001-10-15	Astion Development Aps	Chemical complex comprising a substituted pyridine carboxy derivative and a glucosaminoglycan
IL137559A (en) *	2000-07-27	2006-12-31	Amnon Sintov	A system for administering drugs through the skin
DE10053053A1 (de)	2000-10-19	2002-05-16	Knoell Hans Forschung Ev	Pharmazeutische Formulierungen zur Hemmung von entzündlichen Arthritiden
US20030162732A1 (en) *	2001-07-05	2003-08-28	Astion Development A/S	Combination of aminosugars and cysteine or cysteine derivatives
ITMI20020756A1 (it) *	2002-04-09	2003-10-09	Sinclair Pharma S R L	Composizioni farmaceutiche topiche per il trattamento delle dermatiti
US20060094643A1 (en) *	2002-07-03	2006-05-04	Yuri Svirkin	Compositions of hyaluronic acid and methods of use
RU2329037C2 (ru) *	2003-02-14	2008-07-20	Комбинаторкс, Инкорпорейтед	Комбинированная терапия для лечения иммуновоспалительных заболеваний
DE102004002001A1 (de) *	2004-01-14	2005-08-11	Reinmüller, Johannes, Dr.med.	Mittel zur Behandlung von entzündlichen Erkrankungen
GB0411165D0 (en) *	2004-05-19	2004-06-23	Bionovate Ltd	Hyaluronic acid containing pharmaceutical or veterinary compounds
ITPD20050168A1 (it) *	2005-06-01	2006-12-02	Fidia Advanced Biopolymers Srl	Formulazioni di acido lipoico ed acido ialuronico e o suoi derivati e loro impiego in campo farmaceutico e cosmetico
RU2302231C1 (ru) *	2006-02-08	2007-07-10	Александр Егорович Петренко	Глазные капли для лечения синдрома сухого глаза
ITPD20060219A1 (it) *	2006-05-31	2007-12-01	Fidia Farmaceutici	Composizioni farmaceutiche contenenti acido ialuronico solfatato nel trattamento dell'osteoartrosi
ITMI20071724A1 (it) *	2007-09-05	2009-03-06	Fidia Farmaceutici	Formulazioni topiche antivirali in forma di gel bioadesivo
IT1397247B1 (it) *	2009-05-14	2013-01-04	Fidia Farmaceutici	Nuovi agenti regolatori dell'attivita' citochinica

2009
- 2009-05-14 IT ITPD2009A000134A patent/IT1397246B1/it active
2010
- 2010-05-14 SM SM20190015T patent/SMT201900015T1/it unknown
- 2010-05-14 EP EP18185228.6A patent/EP3417855B1/en active Active
- 2010-05-14 CA CA2995610A patent/CA2995610C/en active Active
- 2010-05-14 SI SI201031318A patent/SI2429515T1/sl unknown
- 2010-05-14 PL PL10721126T patent/PL2429515T3/pl unknown
- 2010-05-14 PT PT107211260T patent/PT2429515T/pt unknown
- 2010-05-14 ES ES16178620T patent/ES2704921T3/es active Active
- 2010-05-14 EP EP10721126.0A patent/EP2429515B1/en active Active
- 2010-05-14 US US13/320,000 patent/US20120121572A1/en active Granted
- 2010-05-14 CA CA2761628A patent/CA2761628C/en active Active
- 2010-05-14 ES ES18185228T patent/ES2808575T3/es active Active
- 2010-05-14 RU RU2011145992/15A patent/RU2543354C2/ru active
- 2010-05-14 LT LTEP10721126.0T patent/LT2429515T/lt unknown
- 2010-05-14 US US13/320,000 patent/US9504708B2/en active Active
- 2010-05-14 ES ES10721126.0T patent/ES2601681T3/es active Active
- 2010-05-14 HU HUE10721126A patent/HUE030673T2/hu unknown
- 2010-05-14 HR HRP20161574TT patent/HRP20161574T1/hr unknown
- 2010-05-14 CN CN201080020708.3A patent/CN102427808B/zh active Active
- 2010-05-14 EP EP16178620.7A patent/EP3103449B1/en active Active
- 2010-05-14 SM SM20200522T patent/SMT202000522T1/it unknown
- 2010-05-14 WO PCT/EP2010/003050 patent/WO2010130468A1/en not_active Ceased
2014
- 2014-11-21 RU RU2014146985A patent/RU2673066C2/ru active
- 2014-11-21 RU RU2014146977A patent/RU2673661C2/ru active
2016
- 2016-10-27 US US15/336,498 patent/US10435483B2/en active Active
- 2016-12-14 SM SM201600455T patent/SMT201600455B/it unknown
2019
- 2019-08-26 US US16/550,810 patent/US11198741B2/en active Active

Also Published As

Publication number	Publication date
SI2429515T1 (sl)	2016-12-30
PT2429515T (pt)	2016-11-10
US20170107303A1 (en)	2017-04-20
SMT201600455B (it)	2017-01-10
CA2761628C (en)	2018-04-10
RU2014146977A (ru)	2016-06-10
EP3103449A3 (en)	2017-02-15
US11198741B2 (en)	2021-12-14
CA2995610C (en)	2020-04-28
ES2808575T3 (es)	2021-03-01
IT1397246B1 (it)	2013-01-04
EP3103449B1 (en)	2018-10-17
US10435483B2 (en)	2019-10-08
RU2543354C2 (ru)	2015-02-27
EP3417855A1 (en)	2018-12-26
US9504708B2 (en)	2016-11-29
CA2761628A1 (en)	2010-11-18
RU2014146985A3 (it)	2018-06-05
CN102427808A (zh)	2012-04-25
HUE030673T2 (hu)	2017-05-29
CA2995610A1 (en)	2010-11-18
CN102427808B (zh)	2020-05-19
RU2011145992A (ru)	2013-06-20
RU2014146977A3 (it)	2018-06-05
LT2429515T (lt)	2016-12-12
SMT201900015T1 (it)	2019-02-28
EP3417855B1 (en)	2020-07-01
ES2601681T3 (es)	2017-02-15
RU2014146985A (ru)	2016-06-10
PL2429515T3 (pl)	2017-02-28
EP2429515A1 (en)	2012-03-21
US20120121572A1 (en)	2012-05-17
EP2429515B1 (en)	2016-09-07
WO2010130468A1 (en)	2010-11-18
ITPD20090134A1 (it)	2010-11-15
RU2673661C2 (ru)	2018-11-29
HRP20161574T1 (hr)	2016-12-30
ES2704921T3 (es)	2019-03-20
US20200010573A1 (en)	2020-01-09
RU2673066C2 (ru)	2018-11-22
EP3103449A2 (en)	2016-12-14

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