SU1318149A3 - Способ получени вакцины против таежного весенне-летнего энцефалита - Google Patents

Способ получени вакцины против таежного весенне-летнего энцефалита Download PDF

Info

Publication number: SU1318149A3
Authority: SU; USSR - Soviet Union
Prior art keywords: virus; fractions; carried out; vaccine against; ultracentrifugation
Prior art date: 1978-12-22

Application number

SU792854825K

Other languages

English (en)

Russian (ru)

Inventor

Хайнц Франц

Кунц Кристиан

Фаума Йоханн

Шварц Отто

Original Assignee

Иммуно Аг Фюр Хемиш-Медицинише Продукте (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-22

Filing date

1979-12-21

Publication date

1987-06-15

1979-12-21 Application filed by Иммуно Аг Фюр Хемиш-Медицинише Продукте (Фирма) filed Critical Иммуно Аг Фюр Хемиш-Медицинише Продукте (Фирма)

1987-06-15 Application granted granted Critical

1987-06-15 Publication of SU1318149A3 publication Critical patent/SU1318149A3/ru

Links

229960005486 vaccine Drugs 0.000 title claims abstract description 7
238000000034 method Methods 0.000 title claims description 10
208000004006 Tick-borne encephalitis Diseases 0.000 title 1
241000700605 Viruses Species 0.000 claims abstract description 19
239000000725 suspension Substances 0.000 claims abstract description 14
238000005119 centrifugation Methods 0.000 claims abstract description 4
239000002245 particle Substances 0.000 claims abstract description 3
238000004062 sedimentation Methods 0.000 claims abstract description 3
206010014599 encephalitis Diseases 0.000 claims abstract 2
229930006000 Sucrose Natural products 0.000 claims description 8
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 8
239000005720 sucrose Substances 0.000 claims description 8
238000010790 dilution Methods 0.000 claims description 5
239000012895 dilution Substances 0.000 claims description 5
102000008100 Human Serum Albumin Human genes 0.000 claims description 4
108091006905 Human Serum Albumin Proteins 0.000 claims description 4
238000005199 ultracentrifugation Methods 0.000 claims description 4
102000007327 Protamines Human genes 0.000 claims description 3
108010007568 Protamines Proteins 0.000 claims description 3
230000008033 biological extinction Effects 0.000 claims description 3
210000002308 embryonic cell Anatomy 0.000 claims description 3
239000007853 buffer solution Substances 0.000 claims description 2
229950008679 protamine sulfate Drugs 0.000 claims description 2
238000005352 clarification Methods 0.000 claims 2
239000012530 fluid Substances 0.000 claims 1
230000002779 inactivation Effects 0.000 claims 1
239000007788 liquid Substances 0.000 claims 1
239000008363 phosphate buffer Substances 0.000 claims 1
238000000746 purification Methods 0.000 claims 1
241000271566 Aves Species 0.000 abstract 1
238000002835 absorbance Methods 0.000 abstract 1
238000012258 culturing Methods 0.000 abstract 1
238000002298 density-gradient ultracentrifugation Methods 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
230000000415 inactivating effect Effects 0.000 abstract 1
210000001161 mammalian embryo Anatomy 0.000 abstract 1
201000011475 meningoencephalitis Diseases 0.000 abstract 1
230000001681 protective effect Effects 0.000 description 5
239000000243 solution Substances 0.000 description 4
210000004027 cell Anatomy 0.000 description 3
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
241000287828 Gallus gallus Species 0.000 description 2
241000699670 Mus sp. Species 0.000 description 2
239000000872 buffer Substances 0.000 description 2
LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 2
229940079593 drug Drugs 0.000 description 2
239000003814 drug Substances 0.000 description 2
239000002953 phosphate buffered saline Substances 0.000 description 2
239000000047 product Substances 0.000 description 2
241001385733 Aesculus indica Species 0.000 description 1
241000272525 Anas platyrhynchos Species 0.000 description 1
235000010469 Glycine max Nutrition 0.000 description 1
244000068988 Glycine max Species 0.000 description 1
102000010029 Homer Scaffolding Proteins Human genes 0.000 description 1
108010077223 Homer Scaffolding Proteins Proteins 0.000 description 1
241000726306 Irus Species 0.000 description 1
241000497429 Obus Species 0.000 description 1
235000014676 Phragmites communis Nutrition 0.000 description 1
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
239000006143 cell culture medium Substances 0.000 description 1
235000013330 chicken meat Nutrition 0.000 description 1
238000004140 cleaning Methods 0.000 description 1
230000015271 coagulation Effects 0.000 description 1
238000005345 coagulation Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000002708 enhancing effect Effects 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
230000005484 gravity Effects 0.000 description 1
239000001963 growth medium Substances 0.000 description 1
239000012535 impurity Substances 0.000 description 1
238000011534 incubation Methods 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
239000002609 medium Substances 0.000 description 1
239000000203 mixture Substances 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
229940048914 protamine Drugs 0.000 description 1
239000010802 sludge Substances 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000000108 ultra-filtration Methods 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B28—WORKING CEMENT, CLAY, OR STONE
- B28D—WORKING STONE OR STONE-LIKE MATERIALS
- B28D1/00—Working stone or stone-like materials, e.g. brick, concrete or glass, not provided for elsewhere; Machines, devices, tools therefor
- B28D1/02—Working stone or stone-like materials, e.g. brick, concrete or glass, not provided for elsewhere; Machines, devices, tools therefor by sawing
- B28D1/06—Working stone or stone-like materials, e.g. brick, concrete or glass, not provided for elsewhere; Machines, devices, tools therefor by sawing with reciprocating saw-blades
- B28D1/068—Components, e.g. guiding means, vibrations damping means, frames, driving means, suspension
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Mycology (AREA)
Mechanical Engineering (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Mining & Mineral Resources (AREA)
Microbiology (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

SU792854825K 1978-12-22 1979-12-21 Способ получени вакцины против таежного весенне-летнего энцефалита SU1318149A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AT922078A AT358167B (de)	1978-12-22	1978-12-22	Verfahren zur herstellung von fruehsommer- -meningoenzephalitis-virus (fsme-virus)- -vakzinen

Publications (1)

Publication Number	Publication Date
SU1318149A3 true SU1318149A3 (ru)	1987-06-15

Family

ID=3612255

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SU792854825K SU1318149A3 (ru)	1978-12-22	1979-12-21	Способ получени вакцины против таежного весенне-летнего энцефалита
SU792854825A SU1003738A3 (ru)	1978-12-22	1979-12-21	Способ получени вакцины таежного весенне-летнего энцефалитного вируса

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SU792854825A SU1003738A3 (ru)	1978-12-22	1979-12-21	Способ получени вакцины таежного весенне-летнего энцефалитного вируса

Country Status (11)

Country	Link
AT (1)	AT358167B (de)
BE (1)	BE880732A (de)
CH (1)	CH644271A5 (de)
CS (1)	CS223975B2 (de)
DE (1)	DE2950004C2 (de)
FR (1)	FR2444466A1 (de)
GB (1)	GB2038179B (de)
IT (1)	IT1126676B (de)
SE (1)	SE447789B (de)
SU (2)	SU1318149A3 (de)
YU (1)	YU42204B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT384363B (de) *	1982-10-05	1987-11-10	Immuno Ag	Verfahren zur verwendung von antigenreaktiven peptiden zur herstellung von gegen fsme-virusinfektionen wirksamen vakzinen
AT385203B (de) *	1985-04-26	1988-03-10	Immuno Ag	Verfahren zur herstellung einer fruehsommermeningoenzephalitis-virus (fsme-virus)-vakzine
AT393356B (de) *	1989-12-22	1991-10-10	Immuno Ag	Verfahren zur herstellung von fsme-virus-antigen
US5719051A (en) *	1989-12-22	1998-02-17	Immuno Aktiengesellschaft	Perfusion system and a method for the large scale production of virus or virus antigen
AT393277B (de) *	1990-01-04	1991-09-25	Immuno Ag	Verfahren zur herstellung von fruehsommer- meningoenzephalitis-virus (fsme-virus)-antigen
IT1305405B1 (it) *	1998-02-18	2001-05-04	Augusto Cappelli	Telaio di taglio per la segagione di blocchi di pietra, roccia,granito, marmo, o simili.
RU2203089C2 (ru) *	2001-06-28	2003-04-27	Федеральное Государственное унитарное предприятие научно-производственное объединение "Вирион"	Способ получения вакцины клещевого энцефалита

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1152626A (en) *	1967-07-07	1969-05-21	Merck & Co Inc	Rubella Vaccine
GB1453035A (en) *	1972-12-21	1976-10-20	Secr Defence	Virus vaccine production

1978
- 1978-12-22 AT AT922078A patent/AT358167B/de not_active IP Right Cessation
1979
- 1979-12-06 SE SE7910054A patent/SE447789B/sv not_active IP Right Cessation
- 1979-12-12 DE DE2950004A patent/DE2950004C2/de not_active Expired - Lifetime
- 1979-12-12 GB GB7942857A patent/GB2038179B/en not_active Expired
- 1979-12-18 CS CS798966A patent/CS223975B2/cs unknown
- 1979-12-18 CH CH1122379A patent/CH644271A5/de not_active IP Right Cessation
- 1979-12-19 YU YU311779A patent/YU42204B/xx unknown
- 1979-12-19 BE BE0/198645A patent/BE880732A/fr not_active IP Right Cessation
- 1979-12-20 FR FR7931278A patent/FR2444466A1/fr active Granted
- 1979-12-21 IT IT2834179A patent/IT1126676B/it active
- 1979-12-21 SU SU792854825K patent/SU1318149A3/ru active
- 1979-12-21 SU SU792854825A patent/SU1003738A3/ru active

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент GB № 453035. кл. А5В, 1977. Авторское свидетельство СССР № 660389, кл. С 12 N 7/04, 1977, *

Also Published As

Publication number	Publication date
SU1003738A3 (ru)	1983-03-07
IT7928341A0 (it)	1979-12-21
YU311779A (en)	1983-10-31
YU42204B (en)	1988-06-30
GB2038179B (en)	1983-02-16
IT1126676B (it)	1986-05-21
CS223975B2 (en)	1983-11-25
ATA922078A (de)	1980-01-15
DE2950004C2 (de)	1991-04-18
SE7910054L (sv)	1980-06-23
FR2444466A1 (fr)	1980-07-18
SE447789B (sv)	1986-12-15
BE880732A (fr)	1980-04-16
CH644271A5 (de)	1984-07-31
GB2038179A (en)	1980-07-23
FR2444466B1 (de)	1983-07-08
DE2950004A1 (de)	1980-07-03
AT358167B (de)	1980-08-25

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