SU479294A3 - Способ получени производных 1,8-нафтиридина - Google Patents

Способ получени производных 1,8-нафтиридина

Info

Publication number: SU479294A3
Authority: SU; USSR - Soviet Union
Prior art keywords: methyl; oil; preparing; oxo; naphthyridine derivatives
Prior art date: 1972-06-29

Application number

SU1951080A

Other languages

English (en)

Russian (ru)

Inventor

Месарош Золтан

Хермец Иштван

Вашвари Лелле

Хорват Агнеш

Давид Агоштон

Хорват Габор

Ковач Вера

Понгор Марианне

Original Assignee

Хиноин Дьедисер-Еш Ведьесети Термекек Дьяра Рт

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-29

Filing date

1973-06-27

Publication date

1975-07-30

1973-06-27 Application filed by Хиноин Дьедисер-Еш Ведьесети Термекек Дьяра Рт filed Critical Хиноин Дьедисер-Еш Ведьесети Термекек Дьяра Рт

1975-07-30 Application granted granted Critical

1975-07-30 Publication of SU479294A3 publication Critical patent/SU479294A3/ru

Links

238000000034 method Methods 0.000 title description 6
150000005058 1,8-naphthyridines Chemical class 0.000 title 1
239000003921 oil Substances 0.000 description 9
-1 nirrolidinyl) Chemical group 0.000 description 8
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
150000003839 salts Chemical class 0.000 description 5
125000003545 alkoxy group Chemical group 0.000 description 4
125000000217 alkyl group Chemical group 0.000 description 4
125000003710 aryl alkyl group Chemical group 0.000 description 4
150000001875 compounds Chemical class 0.000 description 4
239000013078 crystal Substances 0.000 description 4
MHCVCKDNQYMGEX-UHFFFAOYSA-N 1,1'-biphenyl;phenoxybenzene Chemical group C1=CC=CC=C1C1=CC=CC=C1.C=1C=CC=CC=1OC1=CC=CC=C1 MHCVCKDNQYMGEX-UHFFFAOYSA-N 0.000 description 3
125000003118 aryl group Chemical group 0.000 description 3
229910052736 halogen Inorganic materials 0.000 description 3
150000002367 halogens Chemical class 0.000 description 3
239000012442 inert solvent Substances 0.000 description 3
239000003208 petroleum Substances 0.000 description 3
239000007858 starting material Substances 0.000 description 3
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
125000002252 acyl group Chemical group 0.000 description 2
125000004442 acylamino group Chemical group 0.000 description 2
150000001732 carboxylic acid derivatives Chemical class 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 description 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
239000001257 hydrogen Substances 0.000 description 2
229910052739 hydrogen Inorganic materials 0.000 description 2
125000004435 hydrogen atom Chemical class [H]* 0.000 description 2
BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
150000002825 nitriles Chemical class 0.000 description 2
229910052757 nitrogen Inorganic materials 0.000 description 2
125000004433 nitrogen atom Chemical group N* 0.000 description 2
238000001953 recrystallisation Methods 0.000 description 2
UPQKNTNJVQSGIH-UHFFFAOYSA-N 2,6-dimethylpyrido[1,2-a]pyrimidin-4-one Chemical compound CC1=CC=CC2=NC(C)=CC(=O)N21 UPQKNTNJVQSGIH-UHFFFAOYSA-N 0.000 description 1
KSLLTJJSGWXUMZ-UHFFFAOYSA-N 2,7-dimethyl-1h-1,8-naphthyridin-4-one Chemical compound N1C(C)=CC(=O)C=2C1=NC(C)=CC=2 KSLLTJJSGWXUMZ-UHFFFAOYSA-N 0.000 description 1
PCISLWUXJKQROS-UHFFFAOYSA-N 3,7-dimethyl-1h-1,8-naphthyridin-4-one Chemical compound N1C=C(C)C(=O)C=2C1=NC(C)=CC=2 PCISLWUXJKQROS-UHFFFAOYSA-N 0.000 description 1
OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
JGLMVXWAHNTPRF-CMDGGOBGSA-N CCN1N=C(C)C=C1C(=O)NC1=NC2=CC(=CC(OC)=C2N1C\C=C\CN1C(NC(=O)C2=CC(C)=NN2CC)=NC2=CC(=CC(OCCCN3CCOCC3)=C12)C(N)=O)C(N)=O Chemical compound CCN1N=C(C)C=C1C(=O)NC1=NC2=CC(=CC(OC)=C2N1C\C=C\CN1C(NC(=O)C2=CC(C)=NN2CC)=NC2=CC(=CC(OCCCN3CCOCC3)=C12)C(N)=O)C(N)=O JGLMVXWAHNTPRF-CMDGGOBGSA-N 0.000 description 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 1
101100240886 Rattus norvegicus Nptx2 gene Proteins 0.000 description 1
125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 description 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
239000002253 acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 description 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
125000004432 carbon atom Chemical group C* 0.000 description 1
150000003857 carboxamides Chemical class 0.000 description 1
125000005518 carboxamido group Chemical group 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
229910052801 chlorine Inorganic materials 0.000 description 1
238000001816 cooling Methods 0.000 description 1
125000004663 dialkyl amino group Chemical group 0.000 description 1
125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 description 1
ZLYHSYOPYSDSHB-UHFFFAOYSA-N ethyl 6-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carboxylate Chemical compound C1=CC=C(C)N2C(=O)C(C(=O)OCC)=CN=C21 ZLYHSYOPYSDSHB-UHFFFAOYSA-N 0.000 description 1
235000019253 formic acid Nutrition 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
235000010446 mineral oil Nutrition 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
125000005936 piperidyl group Chemical group 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000007787 solid Substances 0.000 description 1
125000000547 substituted alkyl group Chemical group 0.000 description 1
125000003107 substituted aryl group Chemical group 0.000 description 1
238000003419 tautomerization reaction Methods 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SU1951080A 1972-06-29 1973-06-27 Способ получени производных 1,8-нафтиридина SU479294A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HUME001512 HU165405B (cs)	1972-06-29	1972-06-29

Publications (1)

Publication Number	Publication Date
SU479294A3 true SU479294A3 (ru)	1975-07-30

Family

ID=10999288

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU1951080A SU479294A3 (ru)	1972-06-29	1973-06-27	Способ получени производных 1,8-нафтиридина

Country Status (9)

Country	Link
JP (1)	JPS527000B2 (cs)
BE (1)	BE801669A (cs)
CS (1)	CS184873B1 (cs)
ES (1)	ES416973A1 (cs)
FR (1)	FR2190820B1 (cs)
GB (1)	GB1432967A (cs)
HU (1)	HU165405B (cs)
SU (1)	SU479294A3 (cs)
YU (1)	YU175973A (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3644825A1 (de) *	1986-12-31	1988-07-14	Basf Ag	Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide
SK1822001A3 (en) *	1998-08-11	2002-08-06	Pfizer Prod Inc	Substituted 1,8-naphthyridin-4(1h)-ones as phosphodiesterase 4 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH66A (de) *		1889-01-08	J Kobler	Feueranzünder

1972
- 1972-06-29 HU HUME001512 patent/HU165405B/hu not_active IP Right Cessation
1973
- 1973-06-27 SU SU1951080A patent/SU479294A3/ru active
- 1973-06-28 GB GB3089973A patent/GB1432967A/en not_active Expired
- 1973-06-28 JP JP48073235A patent/JPS527000B2/ja not_active Expired
- 1973-06-29 CS CS474873A patent/CS184873B1/cs unknown
- 1973-06-29 FR FR7323957A patent/FR2190820B1/fr not_active Expired
- 1973-06-29 BE BE132909A patent/BE801669A/xx not_active IP Right Cessation
- 1973-06-30 ES ES416973A patent/ES416973A1/es not_active Expired
- 1973-07-28 YU YU175973A patent/YU175973A/xx unknown

Also Published As

Publication number	Publication date
YU175973A (en)	1982-05-31
JPS4962498A (cs)	1974-06-17
GB1432967A (cs)	1976-04-22
CS184873B1 (en)	1978-09-15
ES416973A1 (es)	1976-03-16
FR2190820B1 (cs)	1976-06-18
FR2190820A1 (cs)	1974-02-01
BE801669A (fr)	1973-10-15
HU165405B (cs)	1974-08-28
JPS527000B2 (cs)	1977-02-26

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