SU518130A3 - "Способ получени фталазино(2,3-в) фталазин-5(14н) - Google Patents

"Способ получени фталазино(2,3-в) фталазин-5(14н)

Info

Publication number: SU518130A3
Authority: SU; USSR - Soviet Union
Prior art keywords: catalyst; phthalazino; acid; water; solution
Prior art date: 1973-04-27

Application number

SU2019273A

Other languages

English (en)

Russian (ru)

Inventor

Джанантонио Анаклето

Коко Антонио

Original Assignee

Группо Лепетит С.П.А.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-04-27

Filing date

1974-04-26

Publication date

1976-06-15

1974-04-26 Application filed by Группо Лепетит С.П.А. filed Critical Группо Лепетит С.П.А.

1976-06-15 Application granted granted Critical

1976-06-15 Publication of SU518130A3 publication Critical patent/SU518130A3/ru

Links

238000000034 method Methods 0.000 title claims description 9
239000003054 catalyst Substances 0.000 claims description 10
239000002253 acid Substances 0.000 claims description 7
239000000047 product Substances 0.000 claims description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
229910052739 hydrogen Inorganic materials 0.000 claims description 6
239000001257 hydrogen Substances 0.000 claims description 6
238000005984 hydrogenation reaction Methods 0.000 claims description 6
239000000203 mixture Substances 0.000 claims description 6
229910052763 palladium Inorganic materials 0.000 claims description 6
LZRPGFXKXJHZIR-UHFFFAOYSA-N 2-(3-oxo-1h-2-benzofuran-1-yl)phthalazin-1-one Chemical compound N1=CC2=CC=CC=C2C(=O)N1C1OC(=O)C2=CC=CC=C21 LZRPGFXKXJHZIR-UHFFFAOYSA-N 0.000 claims description 4
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 4
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 4
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 4
238000001816 cooling Methods 0.000 claims description 4
238000001914 filtration Methods 0.000 claims description 3
CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims description 2
238000006243 chemical reaction Methods 0.000 claims description 2
239000000284 extract Substances 0.000 claims description 2
150000002431 hydrogen Chemical class 0.000 claims description 2
229910052759 nickel Inorganic materials 0.000 claims description 2
238000010992 reflux Methods 0.000 claims description 2
239000008096 xylene Substances 0.000 claims description 2
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 6
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 6
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
230000002378 acidificating effect Effects 0.000 claims 2
125000001931 aliphatic group Chemical group 0.000 claims 2
229910052799 carbon Inorganic materials 0.000 claims 2
229910052751 metal Inorganic materials 0.000 claims 2
239000002184 metal Substances 0.000 claims 2
229910052725 zinc Inorganic materials 0.000 claims 2
239000011701 zinc Substances 0.000 claims 2
VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims 1
125000005907 alkyl ester group Chemical group 0.000 claims 1
229910052782 aluminium Inorganic materials 0.000 claims 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
239000000908 ammonium hydroxide Substances 0.000 claims 1
239000003638 chemical reducing agent Substances 0.000 claims 1
239000012043 crude product Substances 0.000 claims 1
238000002425 crystallisation Methods 0.000 claims 1
230000008025 crystallization Effects 0.000 claims 1
238000000605 extraction Methods 0.000 claims 1
230000020477 pH reduction Effects 0.000 claims 1
229910052697 platinum Inorganic materials 0.000 claims 1
229910052703 rhodium Inorganic materials 0.000 claims 1
229910052707 ruthenium Inorganic materials 0.000 claims 1
150000003839 salts Chemical class 0.000 claims 1
229910052718 tin Inorganic materials 0.000 claims 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 27
238000002360 preparation method Methods 0.000 description 7
239000000725 suspension Substances 0.000 description 7
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 6
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
KDLHZDBZIXYQEI-UHFFFAOYSA-N palladium Substances [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 6
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
239000002023 wood Substances 0.000 description 4
239000003610 charcoal Substances 0.000 description 3
239000003245 coal Substances 0.000 description 3
238000005406 washing Methods 0.000 description 3
NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 description 2
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 description 2
239000002244 precipitate Substances 0.000 description 2
229910000029 sodium carbonate Inorganic materials 0.000 description 2
239000002904 solvent Substances 0.000 description 2
235000011149 sulphuric acid Nutrition 0.000 description 2
241000701085 Human alphaherpesvirus 3 Species 0.000 description 1
-1 Methyl orthopropylbenzoic acid ester Chemical class 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
YKIOKAURTKXMSB-UHFFFAOYSA-N adams's catalyst Chemical compound O=[Pt]=O YKIOKAURTKXMSB-UHFFFAOYSA-N 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
XSCHRSMBECNVNS-UHFFFAOYSA-N benzopyrazine Natural products N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 description 1
238000001354 calcination Methods 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
IJAPPYDYQCXOEF-UHFFFAOYSA-N phthalazin-1(2H)-one Chemical compound C1=CC=C2C(=O)NN=CC2=C1 IJAPPYDYQCXOEF-UHFFFAOYSA-N 0.000 description 1
LFSXCDWNBUNEEM-UHFFFAOYSA-N phthalazine Chemical compound C1=NN=CC2=CC=CC=C21 LFSXCDWNBUNEEM-UHFFFAOYSA-N 0.000 description 1
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
235000017550 sodium carbonate Nutrition 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
210000004243 sweat Anatomy 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SU2019273A 1973-04-27 1974-04-26 "Способ получени фталазино(2,3-в) фталазин-5(14н) SU518130A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2020073A GB1412527A (en)	1973-04-27	1973-04-27	Method for the preparation of phthalqzino o2,3-b phthalazine-5 14h, 12 7h-dione

Publications (1)

Publication Number	Publication Date
SU518130A3 true SU518130A3 (ru)	1976-06-15

Family

ID=10142085

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU2019273A SU518130A3 (ru)	1973-04-27	1974-04-26	"Способ получени фталазино(2,3-в) фталазин-5(14н)

Country Status (25)

Country	Link
US (1)	US3886154A (2)
JP (1)	JPS5221519B2 (2)
AR (1)	AR198571A1 (2)
AT (1)	AT333773B (2)
AU (1)	AU476794B2 (2)
BE (1)	BE814249A (2)
CA (1)	CA1021339A (2)
CH (2)	CH589087A5 (2)
CS (2)	CS179443B2 (2)
DD (1)	DD110871A5 (2)
DE (1)	DE2414681C3 (2)
DK (1)	DK138329B (2)
EG (1)	EG11284A (2)
ES (1)	ES425748A1 (2)
FR (1)	FR2227275B1 (2)
GB (1)	GB1412527A (2)
HU (1)	HU169350B (2)
IN (1)	IN138635B (2)
NL (1)	NL7405323A (2)
NO (1)	NO140302C (2)
PL (1)	PL88726B1 (2)
RO (1)	RO63625A2 (2)
SE (1)	SE419221B (2)
SU (1)	SU518130A3 (2)
ZA (1)	ZA741850B (2)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62162066U (2) *	1986-04-07	1987-10-15
JPS62259897A (ja) *	1986-04-29	1987-11-12	花山　重次郎	綴込用フアイル及びフアイル方法
JPH0193400A (ja) *	1987-05-29	1989-04-12	Jujiro Hanayama	綴込用ファイル及びファイル方法
CN106008478A (zh) *	2016-06-16	2016-10-12	桂林理工大学	邻羧基苯甲醛缩水合肼希夫碱及其制备方法
KR102545875B1 (ko) *	2018-07-20	2023-06-23	주식회사 제우스	바이오칩 기판 처리지그 및 바이오칩 기판 처리방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1199482A (en) *	1967-02-01	1970-07-22	Lepetit Spa	Novel-Phthalazino [2,3-b] Pthalazine Derivatives, the preparation thereof and Compositions containing them

1973
- 1973-04-27 GB GB2020073A patent/GB1412527A/en not_active Expired
1974
- 1974-03-21 ZA ZA00741850A patent/ZA741850B/xx unknown
- 1974-03-22 AU AU67006/74A patent/AU476794B2/en not_active Expired
- 1974-03-27 DE DE2414681A patent/DE2414681C3/de not_active Expired
- 1974-03-28 IN IN699/CAL/74A patent/IN138635B/en unknown
- 1974-03-29 NO NO741127A patent/NO140302C/no unknown
- 1974-04-17 EG EG123/74A patent/EG11284A/xx active
- 1974-04-18 AR AR253347A patent/AR198571A1/es active
- 1974-04-18 US US461837A patent/US3886154A/en not_active Expired - Lifetime
- 1974-04-19 NL NL7405323A patent/NL7405323A/xx not_active Application Discontinuation
- 1974-04-23 DK DK221274AA patent/DK138329B/da unknown
- 1974-04-25 RO RO78560A patent/RO63625A2/ro unknown
- 1974-04-25 CH CH65477A patent/CH589087A5/xx not_active IP Right Cessation
- 1974-04-25 AT AT343074A patent/AT333773B/de not_active IP Right Cessation
- 1974-04-25 CH CH569474A patent/CH589085A5/xx not_active IP Right Cessation
- 1974-04-25 PL PL1974170583A patent/PL88726B1/pl unknown
- 1974-04-26 CA CA198,289A patent/CA1021339A/en not_active Expired
- 1974-04-26 HU HULE746A patent/HU169350B/hu unknown
- 1974-04-26 SU SU2019273A patent/SU518130A3/ru active
- 1974-04-26 JP JP49047455A patent/JPS5221519B2/ja not_active Expired
- 1974-04-26 CS CS7400003010A patent/CS179443B2/cs unknown
- 1974-04-26 CS CS7700000413A patent/CS184350B2/cs unknown
- 1974-04-26 BE BE143669A patent/BE814249A/xx unknown
- 1974-04-26 FR FR7414732A patent/FR2227275B1/fr not_active Expired
- 1974-04-26 DD DD178162A patent/DD110871A5/xx unknown
- 1974-04-27 ES ES425748A patent/ES425748A1/es not_active Expired
1977
- 1977-04-13 SE SE7704257A patent/SE419221B/xx unknown

Also Published As

Publication number	Publication date
US3886154A (en)	1975-05-27
SE7704257L (sv)	1977-04-13
ZA741850B (en)	1975-03-26
EG11284A (en)	1977-08-15
ATA343074A (de)	1976-04-15
SE419221B (sv)	1981-07-20
AT333773B (de)	1976-12-10
DD110871A5 (2)	1975-01-12
AU6700674A (en)	1975-09-25
DK138329C (2)	1979-01-29
NO140302B (no)	1979-04-30
FR2227275B1 (2)	1977-10-21
BE814249A (fr)	1974-08-16
DE2414681A1 (de)	1974-11-21
CH589085A5 (2)	1977-06-30
CA1021339A (en)	1977-11-22
GB1412527A (en)	1975-11-05
PL88726B1 (2)	1976-09-30
NO741127L (no)	1974-10-29
HU169350B (2)	1976-11-28
FR2227275A1 (2)	1974-11-22
RO63625A2 (ro)	1978-09-15
JPS5013400A (2)	1975-02-12
DK138329B (da)	1978-08-14
CH589087A5 (2)	1977-06-30
NO140302C (no)	1979-08-08
IN138635B (2)	1976-03-06
ES425748A1 (es)	1976-06-16
CS184350B2 (en)	1978-08-31
NL7405323A (2)	1974-10-29
JPS5221519B2 (2)	1977-06-10
DE2414681B2 (de)	1980-04-30
CS179443B2 (en)	1977-10-31
AU476794B2 (en)	1976-10-07
AR198571A1 (es)	1974-06-28
DE2414681C3 (de)	1981-01-08

Publication	Publication Date	Title
KR100192007B1 (ko)	1999-06-15	락탐 유도체의 제조방법
Kanakarajan et al.	1986	Synthesis and some reactions of hexaazatriphenylenehexanitrile, a hydrogen-free polyfunctional heterocycle with D3h symmetry
SU509220A3 (ru)	1976-03-30	Способ получени производныхкарбазола или их опти-ческих изомеров,или их солей
US3242190A (en)	1966-03-22	3-hydroxy-5-aminomethylisoxazole compounds
SU576940A3 (ru)	1977-10-15	Способ получени производных триазолопиридазина или их солей
SU518130A3 (ru)	1976-06-15	"Способ получени фталазино(2,3-в) фталазин-5(14н)
Wenkert et al.	1964	Derivatives of Hemimellitic Acid. A Synthesis of Erythrocentaurin1
CH558362A (de)	1975-01-31	Verfahren zur herstellung von endoaethano-tetrahydrothebainen bzw. -oripavinen.
US4284797A (en)	1981-08-18	Process for separating mixtures of 3- and 4-nitrophthalic acid
US2785163A (en)	1957-03-12	Process for the formylation of a 5-nitrosouracil
US2380479A (en)	1945-07-31	dl-tryptophane and processes for producing the same
US2723268A (en)	1955-11-08	Process and intermediates for preparing
US2766245A (en)	1956-10-09	dehydroisomorphinanes intermedi-
NZ204367A (en)	1985-08-30	2-(6-methoxy-2-naphthyl)propionic acid,preparation by resolution method and glucamine resolving agent
US2695902A (en)	1954-11-30	2-methyl-3-(beta-chloroethyl)-4, 6-dichloro pyridine and method of making same
SU520916A3 (ru)	1976-07-05	Способ получени фталазино /2,3-в/ фталазин-5(14н),12(7н)диона
JPS6031824B2 (ja)	1985-07-24	ヒドロキシフェニルピペリジニルメタノ−ル誘導体の製法
Ferrier et al.	1960	704. Some derivatives of 2, 7-naphthyridine
NO137093B (no)	1977-09-19	Fremgangsm}te til fremstilling av 2,4-diamino-5-benzylpyrimidiner
US2785162A (en)	1957-03-12	Process for the formylation of a 5 nitrosouracil
Collins et al.	1958	The Reaction of Reissert Compounds and Related 1-Acyl-1, 2-dihydroquinoline Derivatives1
HU186528B (en)	1985-08-28	Process for producing tetronnoic acid
US2948749A (en)	1960-08-09	Production of 1, 2, 3, 4-tetrahydro-1-naphthoic acid
SU703019A3 (ru)	1979-12-05	Способ получени гидразидов индазол-3-карбоновой кислоты или их солей
US3578670A (en)	1971-05-11	Nicotinamide intermediates and process for preparing same