SU893132A3 - Способ получени моногидратной кристаллической формы N-2-(6-метокси)бензтиазолил-N-фенилмочевины - Google Patents
Способ получени моногидратной кристаллической формы N-2-(6-метокси)бензтиазолил-N-фенилмочевины Download PDFInfo
- Publication number
- SU893132A3 SU893132A3 SU802877707A SU2877707A SU893132A3 SU 893132 A3 SU893132 A3 SU 893132A3 SU 802877707 A SU802877707 A SU 802877707A SU 2877707 A SU2877707 A SU 2877707A SU 893132 A3 SU893132 A3 SU 893132A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- text
- methoxy
- benzthiazolyl
- phenylurea
- crystalline form
- Prior art date
Links
- 150000004682 monohydrates Chemical class 0.000 title claims abstract description 4
- 238000000034 method Methods 0.000 title claims description 5
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- 238000000634 powder X-ray diffraction Methods 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 239000004202 carbamide Substances 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 230000003362 replicative effect Effects 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- KZHGPDSVHSDCMX-UHFFFAOYSA-N 6-methoxy-1,3-benzothiazol-2-amine Chemical compound COC1=CC=C2N=C(N)SC2=C1 KZHGPDSVHSDCMX-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 206010011684 Cutaneous tuberculosis Diseases 0.000 description 1
- 150000008064 anhydrides Chemical group 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229940124644 immune regulator Drugs 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 231100000219 mutagenic Toxicity 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- DGTNSSLYPYDJGL-UHFFFAOYSA-N phenyl isocyanate Chemical compound O=C=NC1=CC=CC=C1 DGTNSSLYPYDJGL-UHFFFAOYSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/010,553 US4223153A (en) | 1979-02-09 | 1979-02-09 | Crystalline forms of N-2-(6-methoxy)benzothiazolyl N'-phenyl urea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU893132A3 true SU893132A3 (ru) | 1981-12-23 |
Family
ID=21746293
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU802877707A SU893132A3 (ru) | 1979-02-09 | 1980-02-08 | Способ получени моногидратной кристаллической формы N-2-(6-метокси)бензтиазолил-N-фенилмочевины |
| SU802877902A SU900811A3 (ru) | 1979-02-09 | 1980-02-08 | Способ получени ангидратной кристаллической формы N-2-(6-метокси)бензтиазолил-N -фенилмочевины |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU802877902A SU900811A3 (ru) | 1979-02-09 | 1980-02-08 | Способ получени ангидратной кристаллической формы N-2-(6-метокси)бензтиазолил-N -фенилмочевины |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4223153A (2) |
| EP (1) | EP0014590A1 (2) |
| JP (1) | JPS55105675A (2) |
| AR (1) | AR225303A1 (2) |
| AU (1) | AU5524080A (2) |
| BE (1) | BE881563A (2) |
| CA (2) | CA1131645A (2) |
| DD (2) | DD149068A5 (2) |
| DK (2) | DK52880A (2) |
| ES (2) | ES488425A0 (2) |
| FI (2) | FI800379A7 (2) |
| FR (1) | FR2448538A1 (2) |
| GB (1) | GB2042538A (2) |
| GR (2) | GR70305B (2) |
| IE (1) | IE800232L (2) |
| IL (1) | IL59326A0 (2) |
| IT (1) | IT1193918B (2) |
| LU (1) | LU82141A1 (2) |
| PH (1) | PH15154A (2) |
| PL (2) | PL221872A1 (2) |
| PT (2) | PT70780A (2) |
| SU (2) | SU893132A3 (2) |
| YU (1) | YU29680A (2) |
| ZA (1) | ZA80668B (2) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN182496B (2) * | 1996-02-20 | 1999-04-17 | Reddy Research Foundation | |
| IN191496B (2) | 1999-07-30 | 2003-12-06 | Ranbaxy Lab Ltd | |
| AR062927A1 (es) | 2006-10-11 | 2008-12-17 | Bayer Healthcare Ag | 4- [4-( [ [ 4- cloro-3-( trifluorometil) fenil) carbamoil] amino] -3- fluorofenoxi) -n- metilpiridin-2- carboxamida monohidratada |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4088768A (en) * | 1975-05-06 | 1978-05-09 | Eli Lilly And Company | N-heterocyclic ureas as immune regulants |
-
1979
- 1979-02-09 US US06/010,553 patent/US4223153A/en not_active Expired - Lifetime
-
1980
- 1980-02-05 AU AU55240/80A patent/AU5524080A/en not_active Abandoned
- 1980-02-05 PT PT70780A patent/PT70780A/pt unknown
- 1980-02-05 CA CA345,060A patent/CA1131645A/en not_active Expired
- 1980-02-05 YU YU00296/80A patent/YU29680A/xx unknown
- 1980-02-05 PT PT70779A patent/PT70779A/pt unknown
- 1980-02-05 ZA ZA00800668A patent/ZA80668B/xx unknown
- 1980-02-05 FR FR8002503A patent/FR2448538A1/fr not_active Withdrawn
- 1980-02-06 DD DD80218923A patent/DD149068A5/de unknown
- 1980-02-06 LU LU82141A patent/LU82141A1/fr unknown
- 1980-02-06 GR GR61138A patent/GR70305B/el unknown
- 1980-02-06 BE BE1/9711A patent/BE881563A/fr unknown
- 1980-02-06 PH PH23605A patent/PH15154A/en unknown
- 1980-02-06 GR GR61139A patent/GR70306B/el unknown
- 1980-02-06 IL IL8059326A patent/IL59326A0/xx unknown
- 1980-02-06 JP JP1348280A patent/JPS55105675A/ja active Pending
- 1980-02-06 DD DD80218922A patent/DD157256A5/de unknown
- 1980-02-07 PL PL22187280A patent/PL221872A1/xx unknown
- 1980-02-07 PL PL22187380A patent/PL221873A1/xx unknown
- 1980-02-07 IT IT19771/80A patent/IT1193918B/it active
- 1980-02-07 FI FI800379A patent/FI800379A7/fi not_active Application Discontinuation
- 1980-02-07 DK DK52880A patent/DK52880A/da unknown
- 1980-02-07 DK DK52980A patent/DK52980A/da unknown
- 1980-02-07 IE IE800232A patent/IE800232L/xx unknown
- 1980-02-07 FI FI800378A patent/FI800378A7/fi not_active Application Discontinuation
- 1980-02-07 EP EP80300368A patent/EP0014590A1/en not_active Withdrawn
- 1980-02-07 GB GB8004139A patent/GB2042538A/en not_active Withdrawn
- 1980-02-08 SU SU802877707A patent/SU893132A3/ru active
- 1980-02-08 SU SU802877902A patent/SU900811A3/ru active
- 1980-02-08 ES ES488425A patent/ES488425A0/es active Granted
- 1980-02-08 ES ES488424A patent/ES488424A0/es active Granted
- 1980-02-08 AR AR279909A patent/AR225303A1/es active
-
1982
- 1982-04-23 CA CA000401603A patent/CA1144932A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR70305B (2) | 1982-09-07 |
| FR2448538A1 (fr) | 1980-09-05 |
| IT8019771A0 (it) | 1980-02-07 |
| DK52880A (da) | 1980-08-10 |
| ZA80668B (en) | 1981-09-30 |
| US4223153A (en) | 1980-09-16 |
| GR70306B (2) | 1982-09-07 |
| ES8101570A1 (es) | 1980-12-16 |
| CA1144932A (en) | 1983-04-19 |
| IT1193918B (it) | 1988-08-31 |
| PT70779A (en) | 1980-03-01 |
| ES488424A0 (es) | 1980-12-16 |
| YU29680A (en) | 1983-10-31 |
| IE800232L (en) | 1980-08-09 |
| PL221873A1 (2) | 1980-10-20 |
| PT70780A (en) | 1980-03-01 |
| DK52980A (da) | 1980-08-10 |
| IL59326A0 (en) | 1980-05-30 |
| FI800378A7 (fi) | 1981-01-01 |
| PL221872A1 (2) | 1980-12-15 |
| ES8101571A1 (es) | 1980-12-16 |
| BE881563A (fr) | 1980-08-06 |
| CA1131645A (en) | 1982-09-14 |
| SU900811A3 (ru) | 1982-01-23 |
| AR225303A1 (es) | 1982-03-15 |
| AU5524080A (en) | 1980-08-14 |
| GB2042538A (en) | 1980-09-24 |
| EP0014590A1 (en) | 1980-08-20 |
| PH15154A (en) | 1982-08-24 |
| JPS55105675A (en) | 1980-08-13 |
| DD157256A5 (de) | 1982-10-27 |
| FI800379A7 (fi) | 1981-01-01 |
| LU82141A1 (fr) | 1980-05-07 |
| ES488425A0 (es) | 1980-12-16 |
| DD149068A5 (de) | 1981-06-24 |
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