SV2001000188A - Aminoacidos biciclicos como agentes farmaceuticos - Google Patents

Aminoacidos biciclicos como agentes farmaceuticos

Info

Publication number: SV2001000188A
Authority: SV; El Salvador
Prior art keywords: amino acids; bicycle; pharmaceutical agents; compounds; useful
Prior art date: 1999-10-20

Application number

SV2000000188A

Other languages

English (en)

Spanish (es)

Inventor

David Clive Blakemore

Jean Marie Receveur

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-20

Filing date

2000-10-06

Publication date

2001-09-07

2000-10-06 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2001-09-07 Publication of SV2001000188A publication Critical patent/SV2001000188A/es

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/20—All rings being cycloaliphatic the ring system containing seven carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/22—All rings being cycloaliphatic the ring system containing eight carbon atoms, e.g. pentalene
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
- C07C2602/28—Hydrogenated naphthalenes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Anesthesiology (AREA)
Psychology (AREA)
Pulmonology (AREA)
Vascular Medicine (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Obesity (AREA)

SV2000000188A 1999-10-20 2000-10-06 Aminoacidos biciclicos como agentes farmaceuticos SV2001000188A (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US16072599P	1999-10-20	1999-10-20

Publications (1)

Publication Number	Publication Date
SV2001000188A true SV2001000188A (es)	2001-09-07

Family

ID=22578159

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SV2000000188A SV2001000188A (es)	1999-10-20	2000-10-06	Aminoacidos biciclicos como agentes farmaceuticos

Country Status (50)

Country	Link
US (2)	US6689906B1 (2)
EP (2)	EP1506955B1 (2)
JP (2)	JP3632191B2 (2)
KR (2)	KR100593349B1 (2)
CN (1)	CN1165518C (2)
AP (2)	AP2004003186A0 (2)
AR (2)	AR026087A1 (2)
AT (2)	ATE358116T1 (2)
AU (2)	AU778871B2 (2)
BG (2)	BG108860A (2)
BR (1)	BR0014972B1 (2)
CA (1)	CA2386297C (2)
CO (1)	CO5280060A1 (2)
CR (1)	CR6620A (2)
CU (1)	CU23112A3 (2)
CZ (1)	CZ295960B6 (2)
DE (2)	DE60034157T2 (2)
DO (1)	DOP2000000083A (2)
DZ (1)	DZ3197A1 (2)
EA (1)	EA005206B1 (2)
EC (1)	ECSP045393A (2)
EE (1)	EE200200211A (2)
ES (2)	ES2237464T3 (2)
GE (1)	GEP20043297B (2)
GT (2)	GT200000183AA (2)
HK (1)	HK1049826B (2)
HN (1)	HN2000000224A (2)
HR (2)	HRP20040709A2 (2)
HU (1)	HUP0203325A3 (2)
IL (3)	IL149143A0 (2)
IS (2)	IS6348A (2)
MA (1)	MA26842A1 (2)
MX (1)	MXPA02003229A (2)
MY (1)	MY127678A (2)
NO (2)	NO20021780D0 (2)
NZ (1)	NZ517961A (2)
OA (1)	OA12070A (2)
PA (1)	PA8505201A1 (2)
PE (1)	PE20010740A1 (2)
PL (1)	PL354607A1 (2)
PT (1)	PT1226110E (2)
SI (1)	SI1226110T1 (2)
SK (1)	SK5232002A3 (2)
SV (1)	SV2001000188A (2)
TR (2)	TR200201094T2 (2)
TW (2)	TWI225855B (2)
UA (1)	UA72931C2 (2)
WO (1)	WO2001028978A1 (2)
YU (2)	YU73004A (2)
ZA (1)	ZA200202543B (2)

Families Citing this family (38)

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US7164034B2 (en)	1999-06-10	2007-01-16	Pfizer Inc.	Alpha2delta ligands for fibromyalgia and other disorders
PL359872A1 (en) *	2000-06-26	2004-09-06	Warner-Lambert Company	Gabapentin analogues for sleep disorders
US6620829B2 (en)	2000-10-17	2003-09-16	Warner-Lambert Company	Method of treating noninflammatory cartilage damage
EP1226820A1 (en)	2001-01-26	2002-07-31	Warner-Lambert Company	Use of bicyclic amino acids for preventing and treating visceral pain and gastrointestinal disorders
BR0208922A (pt) *	2001-04-19	2004-04-20	Warner Lambert Co	Aminoácidos bicìclicos ou tricìclicos fundidos
GB2375108A (en) *	2001-05-04	2002-11-06	Warner Lambert Co	Production of a bicycloheptanone
GB2375109A (en) *	2001-05-04	2002-11-06	Warner Lambert Co	Process for preparing bicyclic amino acid
CA2449729C (en) *	2001-06-11	2009-11-03	Xenoport, Inc.	Prodrugs of gaba analogs, compositions and uses thereof
US6818787B2 (en)	2001-06-11	2004-11-16	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en)	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7186855B2 (en)	2001-06-11	2007-03-06	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
CN1625393A (zh)	2002-01-31	2005-06-08	沃纳-兰伯特公司	治疗耳鸣的α2δ配体
PL372210A1 (en) *	2002-02-22	2005-07-11	Warner-Lambert Company Llc	Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2
WO2004002462A2 (en) *	2002-06-27	2004-01-08	Warner-Lambert Company Llc	Use of an alpha2delta ligand such as gabapentin or pregabalin for treating ttention deficit hyperactivity disorder
GB0219024D0 (en) *	2002-08-15	2002-09-25	Pfizer Ltd	Synergistic combinations
US7419981B2 (en)	2002-08-15	2008-09-02	Pfizer Inc.	Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor
JP2005539092A (ja) *	2002-08-15	2005-12-22	ファイザー・インク	縮合二環式または三環式アミノ酸の治療における使用
GB0223072D0 (en)	2002-10-04	2002-11-13	Pfizer Ltd	Cyclic nitromethyl acetic acid derivatives
US7018818B2 (en)	2002-10-04	2006-03-28	Pfizer Inc.	Intermediates in the preparation of therapeutic fused bicyclic amino acids
US7060727B2 (en)	2002-12-11	2006-06-13	Xenoport, Inc.	Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
CA2451267A1 (en)	2002-12-13	2004-06-13	Warner-Lambert Company Llc	Pharmaceutical uses for alpha2delta ligands
AU2003303041B2 (en)	2002-12-13	2008-07-24	Warner-Lambert Company Llc	Alpha-2-delta ligand to treat lower urinary tract symptoms
NZ540591A (en)	2002-12-13	2008-03-28	Warner Lambert Co	Pregabalin derivatives for the treatment of fibromyalgia and other disorders
AU2004271800A1 (en)	2003-09-12	2005-03-24	Pfizer Inc.	Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
WO2006092692A1 (en) *	2005-03-01	2006-09-08	Pfizer Limited	Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
AR061728A1 (es) *	2006-06-30	2008-09-17	Pfizer Prod Inc	Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
CA2673545A1 (en)	2006-12-22	2008-07-03	Recordati Ireland Limited	Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids
EP2657219B1 (en)	2007-09-28	2014-12-10	Daiichi Sankyo Company, Limited	Intermediate for producing bicyclic y-amino acid derivative
JP5557292B2 (ja)	2009-03-26	2014-07-23	第一三共株式会社	二環性γ−アミノ酸誘導体の製造方法
EP2719676B1 (en)	2011-06-08	2017-12-13	Daiichi Sankyo Company, Limited	Method for producing bicyclic compound via iminium salt
WO2012169475A1 (ja)	2011-06-08	2012-12-13	第一三共株式会社	クライゼン転位反応による二環性化合物の製造方法
IN2014MN01046A (2)	2011-12-15	2015-05-01	Daiichi Sankyo Companyltd
EP2837689B1 (en)	2012-04-10	2017-02-15	Daiichi Sankyo Company, Limited	Optical resolution method for bicyclic compound using enzyme
US9066853B2 (en)	2013-01-15	2015-06-30	Warsaw Orthopedic, Inc.	Clonidine compounds in a biodegradable fiber
TWI635071B (zh)	2013-07-08	2018-09-11	第一三共股份有限公司	光學活性二環γ－胺基酸衍生物及其製造方法
WO2018166855A1 (en)	2017-03-16	2018-09-20	Basf Se	Heterobicyclic substituted dihydroisoxazoles
CN113045410A (zh) *	2021-03-29	2021-06-29	华东理工大学	一种双环降二萜类化合物及其合成基因及制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3641129A (en)	1969-06-17	1972-02-08	Merck & Co Inc	Antifibrinolytic compounds
DE2460891C2 (de)	1974-12-21	1982-09-23	Gödecke AG, 1000 Berlin	1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) *	1974-12-21	1978-05-02	Warner-Lambert Company	Treatment of cranial dysfunctions using novel cyclic amino acids
HUP0004310A3 (en)	1997-10-27	2001-11-28	Warner Lambert Co	Cyclic amino acids, and derivatives thereof and pharmaceutical compositions comprising the said compounds as active agents

2000
- 2000-10-05 HN HN2000000224A patent/HN2000000224A/es unknown
- 2000-10-06 SV SV2000000188A patent/SV2001000188A/es not_active Application Discontinuation
- 2000-10-17 GE GE4783A patent/GEP20043297B/en unknown
- 2000-10-17 DZ DZ003197A patent/DZ3197A1/xx active
- 2000-10-17 TR TR2002/01094T patent/TR200201094T2/xx unknown
- 2000-10-17 SI SI200030670T patent/SI1226110T1/xx unknown
- 2000-10-17 HR HRP20040709 patent/HRP20040709A2/xx not_active Application Discontinuation
- 2000-10-17 JP JP2001531783A patent/JP3632191B2/ja not_active Expired - Fee Related
- 2000-10-17 EA EA200200293A patent/EA005206B1/ru unknown
- 2000-10-17 AP AP2004003186A patent/AP2004003186A0/xx unknown
- 2000-10-17 AU AU10920/01A patent/AU778871B2/en not_active Ceased
- 2000-10-17 CZ CZ20021310A patent/CZ295960B6/cs not_active IP Right Cessation
- 2000-10-17 HU HU0203325A patent/HUP0203325A3/hu unknown
- 2000-10-17 KR KR1020027005036A patent/KR100593349B1/ko not_active Expired - Fee Related
- 2000-10-17 NZ NZ517961A patent/NZ517961A/xx unknown
- 2000-10-17 UA UA2002032434A patent/UA72931C2/uk unknown
- 2000-10-17 KR KR1020067002249A patent/KR100566462B1/ko not_active Expired - Fee Related
- 2000-10-17 CA CA2386297A patent/CA2386297C/en not_active Expired - Fee Related
- 2000-10-17 SK SK523-2002A patent/SK5232002A3/sk unknown
- 2000-10-17 EE EEP200200211A patent/EE200200211A/xx unknown
- 2000-10-17 HK HK03101868.4A patent/HK1049826B/zh not_active IP Right Cessation
- 2000-10-17 WO PCT/US2000/028687 patent/WO2001028978A1/en not_active Ceased
- 2000-10-17 IL IL14914300A patent/IL149143A0/xx not_active IP Right Cessation
- 2000-10-17 AT AT04027485T patent/ATE358116T1/de not_active IP Right Cessation
- 2000-10-17 US US10/130,023 patent/US6689906B1/en not_active Expired - Fee Related
- 2000-10-17 TR TR2005/00221T patent/TR200500221T2/xx unknown
- 2000-10-17 CN CNB008145644A patent/CN1165518C/zh not_active Expired - Fee Related
- 2000-10-17 YU YU73004A patent/YU73004A/sh unknown
- 2000-10-17 DE DE60034157T patent/DE60034157T2/de not_active Expired - Lifetime
- 2000-10-17 MX MXPA02003229A patent/MXPA02003229A/es active IP Right Grant
- 2000-10-17 EP EP04027485A patent/EP1506955B1/en not_active Expired - Lifetime
- 2000-10-17 PL PL00354607A patent/PL354607A1/xx not_active Application Discontinuation
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- 2000-10-17 BR BRPI0014972-1A patent/BR0014972B1/pt not_active IP Right Cessation
- 2000-10-17 AT AT00972226T patent/ATE293590T1/de not_active IP Right Cessation
- 2000-10-17 YU YU29302A patent/YU29302A/sh unknown
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- 2000-10-17 DE DE60019628T patent/DE60019628T2/de not_active Expired - Lifetime
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- 2000-10-17 EP EP00972226A patent/EP1226110B1/en not_active Expired - Lifetime
- 2000-10-17 HR HR20020428A patent/HRP20020428B1/xx not_active IP Right Cessation
- 2000-10-17 PT PT00972226T patent/PT1226110E/pt unknown
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- 2000-10-20 TW TW089122115A patent/TWI225855B/zh not_active IP Right Cessation
- 2000-10-20 TW TW093125953A patent/TW200505824A/zh unknown
2002
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- 2002-04-16 CU CU78A patent/CU23112A3/es unknown
- 2002-04-16 NO NO20021780A patent/NO20021780D0/no not_active Application Discontinuation
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- 2002-04-18 CR CR6620A patent/CR6620A/es not_active Application Discontinuation
- 2002-05-10 MA MA26634A patent/MA26842A1/fr unknown
- 2002-05-20 BG BG108860A patent/BG108860A/en unknown
- 2002-05-20 BG BG106719A patent/BG106719A/bg unknown
2004
- 2004-01-21 US US10/762,026 patent/US6835751B2/en not_active Expired - Fee Related
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- 2004-09-14 JP JP2004266488A patent/JP3744928B2/ja not_active Expired - Fee Related
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2005
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Also Published As

Publication number	Publication date
KR100593349B1 (ko)	2006-06-26
YU73004A (sh)	2005-11-28
ECSP045393A (es)	2004-10-23
ZA200202543B (en)	2003-09-23
MY127678A (en)	2006-12-29
ES2282785T3 (es)	2007-10-16
IS6348A (is)	2002-04-17
CA2386297A1 (en)	2001-04-26
CN1382118A (zh)	2002-11-27
NO20043663L (no)	2002-04-16
JP2003512348A (ja)	2003-04-02
CZ295960B6 (cs)	2005-12-14
DE60019628D1 (de)	2005-05-25
SI1226110T1 (en)	2005-08-31
KR20060013701A (ko)	2006-02-13
JP3744928B2 (ja)	2006-02-15
TR200500221T2 (tr)	2005-03-21
IL164060A0 (en)	2005-12-18
EA200200293A1 (ru)	2002-10-31
US6689906B1 (en)	2004-02-10
OA12070A (en)	2003-11-10
BG108860A (en)	2006-03-31
HUP0203325A2 (hu)	2003-02-28
CN1165518C (zh)	2004-09-08
ATE293590T1 (de)	2005-05-15
PA8505201A1 (es)	2002-08-29
AU778871B2 (en)	2004-12-23
CA2386297C (en)	2010-02-09
HK1049826B (zh)	2005-02-25
HK1049826A1 (en)	2003-05-30
MA26842A1 (fr)	2004-12-20
AP2004003186A0 (en)	2004-12-31
JP3632191B2 (ja)	2005-03-23
EP1506955A1 (en)	2005-02-16
DE60019628T2 (de)	2006-01-19
KR20020040900A (ko)	2002-05-30
HN2000000224A (es)	2001-04-11
HRP20020428A2 (en)	2005-02-28
DE60034157T2 (de)	2007-12-13
EP1506955B1 (en)	2007-03-28
NO20021780L (no)	2002-04-16
DE60034157D1 (de)	2007-05-10
NO20021780D0 (no)	2002-04-16
CU23112A3 (es)	2006-02-27
EP1226110B1 (en)	2005-04-20
TR200201094T2 (tr)	2002-09-23
CR6620A (es)	2004-02-02
AU2005201268A1 (en)	2005-04-21
UA72931C2 (uk)	2005-05-16
BR0014972B1 (pt)	2011-09-06
SK5232002A3 (en)	2003-07-01
MXPA02003229A (es)	2002-09-30
DZ3197A1 (fr)	2001-04-26
AR026087A1 (es)	2002-12-26
EE200200211A (et)	2003-06-16
ES2237464T3 (es)	2005-08-01
IL149143A (en)	2007-02-11
HUP0203325A3 (en)	2003-12-29
BG106719A (bg)	2003-02-28
US20040152779A1 (en)	2004-08-05
PL354607A1 (en)	2004-01-26
JP2005036009A (ja)	2005-02-10
NZ517961A (en)	2002-12-20
IS7497A (is)	2004-10-08
PE20010740A1 (es)	2001-07-27
EA005206B1 (ru)	2004-12-30
IL149143A0 (en)	2002-11-10
GEP20043297B (en)	2004-01-12
GT200000183A (es)	2000-10-19
KR100566462B1 (ko)	2006-03-31
WO2001028978A1 (en)	2001-04-26
AU1092001A (en)	2001-04-30
ATE358116T1 (de)	2007-04-15
BR0014972A (pt)	2002-07-16
AP2002002517A0 (en)	2002-06-30
YU29302A (sh)	2005-06-10
AR045456A2 (es)	2005-10-26
US6835751B2 (en)	2004-12-28
TWI225855B (en)	2005-01-01
PT1226110E (pt)	2005-07-29
HRP20040709A2 (en)	2004-12-31
DOP2000000083A (es)	2002-03-30
CO5280060A1 (es)	2003-05-30
EP1226110A1 (en)	2002-07-31
TW200505824A (en)	2005-02-16
HRP20020428B1 (en)	2006-02-28
CZ20021310A3 (cs)	2003-05-14
GT200000183AA (es)	2005-06-17

Legal Events

Date	Code	Title	Description
2005-06-10	FG	Grant
2010-01-25	FD	Lapse

Publication	Publication Date	Title
SV2001000188A (es)	2001-09-07	Aminoacidos biciclicos como agentes farmaceuticos
PA8543501A1 (es)	2002-10-31	Aminoácidos bicíclicos o tricíclicos condensados
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ES2176668T3 (es)	2002-12-01	Aminoacidos ciclicos novedosos como agentes farmaceuticos.
UY28450A1 (es)	2005-03-31	Compuestos heteroarilo de 6 miembros para el tratamiento de trastornos neurodegenerativos.
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UY28484A1 (es)	2005-03-31	Compuestos para el tratamiento de trastornos neurodegenerativos
CL2011002766A1 (es)	2012-05-25	Compuestos derivados de carboxamida, inhibidores de calpaina; composicion farmaceutica que los comprende; y su uso en el tratamiento de enfermedades neurodegenerativas, alzahimer, dolor, entre otras.
GT200500378A (es)	2006-11-28	Macrolidos
BR0304218A (pt)	2004-07-27	ésteres alicìclicos com fragrância de almìscar
ECSP034804A (es)	2003-12-01	Aminoácidos bicíclicos o tricíclicos condensados
CL2007003223A1 (es)	2008-01-11	Compuestos derivados de piperidinil 4-arilsulfonamidas n-sustituidas, que actuan como moduladores de la proteina sfrp-1; proceso para preparar los compuestos; co mposicion farmaceutica que comprende a dichos copmpuestos y uso de los compuestos para preparar medicamentos para el tratamiento de enfermedades.
BR0306855A (pt)	2005-04-05	Método para o tratamento de distúrbios cognitivos
GT200700097A (es)	2009-06-04	Nuevos derivados de fenilpiridinilpiperazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
CL2010001429A1 (es)	2011-07-29	Compuestos derivados de piperazinilo, moduladores del receptor p75ntr de neurotrofinas; procedimiento de preparacion; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades neurodegenerativas centrales y perifericas, depresion, afecciones cardiovasculares y cancer.
GT200400231A (es)	2005-06-09	Compuestos de sulfoniltetrahidro-3h-benzo(e)indol-8-amina como ligandos de la 5-hidroxitriptamina-6.
ECSP088280A (es)	2008-04-28	Compuestos de imidazol para el tratamiento de trastornos neurológicos
DOP2005000049A (es)	2005-12-15	Compuestos de sulfonamidas para el tratamiento de trastornos neurodegererativos
ES2187030T3 (es)	2003-05-16	Una nueva sal.
PA8608601A1 (es)	2005-03-03	Compuestos de oxazol para el tratamiento de trastornos neurodegenerativos
PT1682162E (pt)	2008-03-28	Utilização de opuntia para a produção de um medicamento para o tratamento da depressão
UY29823A1 (es)	2007-05-31	Derivados sustituidos de 7-cloro-3h-imidazol-(4,5-b) piridina, composiciones farmacéuticas que los contienen, procesos para la preparación de los mismos y aplicaciones