TN2009000147A1 - Crystal modifications -3-(1h-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-d ione - Google Patents

Crystal modifications -3-(1h-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-d ione

Info

Publication number: TN2009000147A1
Authority: TN; Tunisia
Prior art keywords: quinazolin; piperazin; indol; pyrrole; methyl
Prior art date: 2006-10-20

Application number

TNP2009000147A

Other languages

English (en)

Inventor

Piotr Karpinski

Stephanie Monnier

Elias Ndzie

Dimitris Papoutsakis

Paul Allen Sutton

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-10-20

Filing date

2009-04-17

Publication date

2010-10-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38921707&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2009000147(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-04-17 Application filed by Novartis Ag filed Critical Novartis Ag

2010-10-18 Publication of TN2009000147A1 publication Critical patent/TN2009000147A1/fr

Links

241000575946 Ione Species 0.000 title 1
LTXREWYXXSTFRX-QGZVFWFLSA-N Linagliptin Chemical compound N=1C=2N(C)C(=O)N(CC=3N=C4C=CC=CC4=C(C)N=3)C(=O)C=2N(CC#CC)C=1N1CCC[C@@H](N)C1 LTXREWYXXSTFRX-QGZVFWFLSA-N 0.000 title 1
239000013078 crystal Substances 0.000 title 1
238000012986 modification Methods 0.000 title 1
230000004048 modification Effects 0.000 title 1
159000000021 acetate salts Chemical class 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

TNP2009000147A 2006-10-20 2009-04-17 Crystal modifications -3-(1h-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-d ione TN2009000147A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US85338406P	2006-10-20	2006-10-20
PCT/US2007/022241 WO2008051440A1 (fr)	2006-10-20	2007-10-18	Modifications cristallines

Publications (1)

Publication Number	Publication Date
TN2009000147A1 true TN2009000147A1 (en)	2010-10-18

Family

ID=38921707

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000147A TN2009000147A1 (en)	2006-10-20	2009-04-17	Crystal modifications -3-(1h-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-d ione

Country Status (23)

Country	Link
US (1)	US8865897B2 (fr)
EP (1)	EP2102195A1 (fr)
JP (1)	JP5302199B2 (fr)
KR (1)	KR20090073231A (fr)
CN (2)	CN101522664B (fr)
AR (1)	AR063491A1 (fr)
AU (1)	AU2007309558B2 (fr)
BR (1)	BRPI0717461A2 (fr)
CA (1)	CA2666965A1 (fr)
CL (1)	CL2007003006A1 (fr)
EC (1)	ECSP099344A (fr)
IL (1)	IL197962A (fr)
MA (1)	MA30886B1 (fr)
MX (1)	MX2009004048A (fr)
MY (1)	MY158026A (fr)
NO (1)	NO20091970L (fr)
NZ (1)	NZ576241A (fr)
PE (1)	PE20081133A1 (fr)
RU (1)	RU2481341C2 (fr)
TN (1)	TN2009000147A1 (fr)
TW (1)	TWI399374B (fr)
WO (1)	WO2008051440A1 (fr)
ZA (1)	ZA200902048B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008112479A1 (fr) *	2007-03-09	2008-09-18	Novartis Ag	Composés
US9017528B2 (en)	2011-04-14	2015-04-28	Tel Nexx, Inc.	Electro chemical deposition and replenishment apparatus
US9005409B2 (en)	2011-04-14	2015-04-14	Tel Nexx, Inc.	Electro chemical deposition and replenishment apparatus
US9303329B2 (en)	2013-11-11	2016-04-05	Tel Nexx, Inc.	Electrochemical deposition apparatus with remote catholyte fluid management

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG159378A1 (en) *	2000-11-07	2010-03-30	Novartis Ag	Indolylmaleimide derivatives as protein kinase c inhibitors
GB0504203D0 (en) *	2005-03-01	2005-04-06	Novartis Ag	Organic compounds
CA2690243A1 (fr)	2007-06-18	2008-12-24	Sanofi-Aventis	Derives du pyrrole en tant qu'antagonistes de p2y12

2007
- 2007-10-18 MX MX2009004048A patent/MX2009004048A/es active IP Right Grant
- 2007-10-18 EP EP07839661A patent/EP2102195A1/fr not_active Withdrawn
- 2007-10-18 BR BRPI0717461-6A2A patent/BRPI0717461A2/pt not_active IP Right Cessation
- 2007-10-18 AR ARP070104622A patent/AR063491A1/es unknown
- 2007-10-18 WO PCT/US2007/022241 patent/WO2008051440A1/fr not_active Ceased
- 2007-10-18 NZ NZ576241A patent/NZ576241A/en not_active IP Right Cessation
- 2007-10-18 CN CN2007800383914A patent/CN101522664B/zh not_active Expired - Fee Related
- 2007-10-18 MY MYPI20091403A patent/MY158026A/en unknown
- 2007-10-18 CA CA002666965A patent/CA2666965A1/fr not_active Abandoned
- 2007-10-18 PE PE2007001411A patent/PE20081133A1/es not_active Application Discontinuation
- 2007-10-18 US US12/445,371 patent/US8865897B2/en not_active Expired - Fee Related
- 2007-10-18 JP JP2009533377A patent/JP5302199B2/ja not_active Expired - Fee Related
- 2007-10-18 CN CN2013101739586A patent/CN103265533A/zh active Pending
- 2007-10-18 AU AU2007309558A patent/AU2007309558B2/en not_active Ceased
- 2007-10-18 KR KR1020097010201A patent/KR20090073231A/ko not_active Ceased
- 2007-10-18 RU RU2009118816/04A patent/RU2481341C2/ru not_active IP Right Cessation
- 2007-10-19 TW TW096139386A patent/TWI399374B/zh not_active IP Right Cessation
- 2007-10-19 CL CL200703006A patent/CL2007003006A1/es unknown
2009
- 2009-03-24 ZA ZA200902048A patent/ZA200902048B/xx unknown
- 2009-04-05 IL IL197962A patent/IL197962A/en not_active IP Right Cessation
- 2009-04-17 TN TNP2009000147A patent/TN2009000147A1/fr unknown
- 2009-05-13 MA MA31867A patent/MA30886B1/fr unknown
- 2009-05-19 EC EC2009009344A patent/ECSP099344A/es unknown
- 2009-05-20 NO NO20091970A patent/NO20091970L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL197962A (en)	2013-08-29
ZA200902048B (en)	2010-01-27
CN101522664B (zh)	2013-06-12
KR20090073231A (ko)	2009-07-02
WO2008051440A1 (fr)	2008-05-02
MX2009004048A (es)	2009-04-27
TW200829572A (en)	2008-07-16
JP5302199B2 (ja)	2013-10-02
PE20081133A1 (es)	2008-09-16
ECSP099344A (es)	2009-06-30
EP2102195A1 (fr)	2009-09-23
AU2007309558B2 (en)	2012-05-24
CN103265533A (zh)	2013-08-28
IL197962A0 (en)	2009-12-24
AU2007309558A1 (en)	2008-05-02
TWI399374B (zh)	2013-06-21
AR063491A1 (es)	2009-01-28
CL2007003006A1 (es)	2008-05-23
RU2481341C2 (ru)	2013-05-10
NO20091970L (no)	2009-05-20
MY158026A (en)	2016-08-30
US8865897B2 (en)	2014-10-21
RU2009118816A (ru)	2010-11-27
CA2666965A1 (fr)	2008-05-02
CN101522664A (zh)	2009-09-02
NZ576241A (en)	2012-05-25
BRPI0717461A2 (pt)	2013-10-08
US20100041884A1 (en)	2010-02-18
MA30886B1 (fr)	2009-11-02
JP2010506927A (ja)	2010-03-04

Publication	Publication Date	Title
WO2010002655A3 (fr)	2010-04-01	Composés et compositions en tant qu’inhibiteurs de kinase
MX2010002336A (es)	2010-03-25	Derivados de 2-bifenil-amino-4-amino-pirimidina como inhibidores de cinasa.
TW200626068A (en)	2006-08-01	Active compounds for seed treatment
UA101346C2 (ru)	2013-03-25	4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и 2-фенилциклогексан-1,3,5-трионы как гербициды
MY146989A (en)	2012-10-15	Kinase inhibitors
MX2009010595A (es)	2009-10-22	Derivados de pirrolopirimidina.
UA101057C2 (en)	2013-02-25	Pyrimidine derivatives as kinase inhibitors
MX2009003316A (es)	2009-04-09	Derivados de pirazina-2-carboxamida como moduladores receptores de cb2.
TW200618800A (en)	2006-06-16	Heterocyclic compounds
SG170772A1 (en)	2011-05-30	Salts of 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl- phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
UA104731C2 (ru)	2014-03-11	Ингибиторы р38 мар-киназ
TW200621721A (en)	2006-07-01	Methods of preparing indazole compounds
WO2008053334A3 (fr)	2008-07-03	Procédé amélioré de préparation de rosuvastatine calcique
TW200728277A (en)	2007-08-01	Bicyclic derivatives as P38 inhibitors
TW200738651A (en)	2007-10-16	Cyclohexyl sulfonamide derivatives
WO2008061108A3 (fr)	2008-07-10	Dérivés de phtalazine
MX2010008226A (es)	2010-10-25	Derivados de difluorobifenilamida para el tratamiento de hipertension ocular.
MX2011012629A (es)	2012-03-06	Inhibidores de actividad de cinasa tipo pirimidina.
MX2009004947A (es)	2009-05-19	Arilsulfonil-pirrolidinas como inhibidores 5-hidroxitriptaminas6 (5-ht6).
MX2011012632A (es)	2012-03-06	Inhibidores de actividad de cinasa tipo pirimidina.
MX2009007336A (es)	2009-07-15	Indazoles substituidos con 5-furopiridinona.
EA201100696A1 (ru)	2011-10-31	1-(арилсульфонил)-4-(пиперазин-1-ил)-1h-бензимидазолы в качестве лигандов 5-гидрокситриптамина-6
MX2011006560A (es)	2011-08-03	Derivados heterociclicos fucionados con oxadiazola utiles para el tratamiento de esclerosis multiple.
ATE466854T1 (de)	2010-05-15	1h-indol-6-ylpiperazin-1-ylmethanonderivate zur verwendung als h3-rezeptormodulatoren
MXPA05013149A (es)	2006-03-17	Derivados de imidazol como antagonistas del receptor de glutamato.