TR199902447T2 - Bir klavülanik asit metal tuzunun hazirlanma prosesi. - Google Patents
Bir klavülanik asit metal tuzunun hazirlanma prosesi.Info
- Publication number
- TR199902447T2 TR199902447T2 TR1999/02447T TR9902447T TR199902447T2 TR 199902447 T2 TR199902447 T2 TR 199902447T2 TR 1999/02447 T TR1999/02447 T TR 1999/02447T TR 9902447 T TR9902447 T TR 9902447T TR 199902447 T2 TR199902447 T2 TR 199902447T2
- Authority
- TR
- Turkey
- Prior art keywords
- metal salt
- clavulanic acid
- acid metal
- preparation process
- preparation
- Prior art date
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 3
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 3
- 229960003324 clavulanic acid Drugs 0.000 title abstract 3
- 239000002184 metal Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- -1 amine salt Chemical class 0.000 abstract 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 abstract 1
- QLOAVXSYZAJECW-UHFFFAOYSA-N methane;molecular fluorine Chemical compound C.FF QLOAVXSYZAJECW-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
Bir klavülanik asit metal tuzunun hazirlanmasi için, bir klavülanik asit organik amin tuzu ile bir metal tuzu ön madde bilesiminin, bir sivi florinatli ve/veya klorinatli hidrokarbon içeren bir sivi ortamda tepkimesini içeren bir proses.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9706846.4A GB9706846D0 (en) | 1997-04-04 | 1997-04-04 | Process |
| GBGB9713887.9A GB9713887D0 (en) | 1997-07-02 | 1997-07-02 | Process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199902447T2 true TR199902447T2 (tr) | 2000-01-21 |
Family
ID=26311317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/02447T TR199902447T2 (tr) | 1997-04-04 | 1998-04-02 | Bir klavülanik asit metal tuzunun hazirlanma prosesi. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US6300495B1 (tr) |
| EP (1) | EP0970087B1 (tr) |
| JP (1) | JP2001521509A (tr) |
| KR (1) | KR100540955B1 (tr) |
| CN (1) | CN1258535C (tr) |
| AR (1) | AR012307A1 (tr) |
| AU (1) | AU736305B2 (tr) |
| BR (1) | BR9808467A (tr) |
| CA (1) | CA2286369C (tr) |
| CO (1) | CO4940460A1 (tr) |
| CZ (1) | CZ298785B6 (tr) |
| DE (1) | DE69838747T2 (tr) |
| DZ (1) | DZ2456A1 (tr) |
| ES (1) | ES2294815T3 (tr) |
| HU (1) | HUP0003621A3 (tr) |
| IL (1) | IL132160A (tr) |
| MA (1) | MA24519A1 (tr) |
| MY (1) | MY120732A (tr) |
| NO (1) | NO325523B1 (tr) |
| NZ (1) | NZ337998A (tr) |
| PE (1) | PE62499A1 (tr) |
| PL (1) | PL190943B1 (tr) |
| TR (1) | TR199902447T2 (tr) |
| TW (1) | TW444016B (tr) |
| WO (1) | WO1998045300A1 (tr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2086946A2 (en) * | 2006-11-29 | 2009-08-12 | Dr. Reddy's Laboratories Ltd. | Rosuvastatin dehydroabietylamine salt |
| CN103833774A (zh) * | 2014-03-21 | 2014-06-04 | 山东新时代药业有限公司 | 一种从克拉维酸钾混粉中回收有效成分的方法 |
| CN109305978A (zh) * | 2017-07-26 | 2019-02-05 | 山东睿鹰先锋制药有限公司 | 一种制备克拉维酸盐的新方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT399155B (de) * | 1992-03-26 | 1995-03-27 | Lek Tovarna Farmacevtskih | Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung |
| SI9300296B (sl) * | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | Postopek in intermedianti za pripravo klavulanske kisline |
| KR100200239B1 (ko) | 1992-10-21 | 1999-06-15 | 김충환 | 클라불란산 칼륨염의 제조방법 |
| GB9305565D0 (en) | 1993-03-18 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds and processes |
| US5821364A (en) * | 1993-03-26 | 1998-10-13 | Gist-Brocades N.V. | Diamine salts of clavulanic acid |
| GB9401969D0 (en) * | 1994-02-02 | 1994-03-30 | Smithkline Beecham Plc | Process |
| SI9400107A (en) * | 1994-03-02 | 1995-10-31 | Lek Tovarna Farmacevtskih | New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804. |
| DE69618045D1 (de) * | 1995-02-25 | 2002-01-31 | Spurcourt Ltd | Clavulansäure Salz |
| SI9500074A (en) * | 1995-03-10 | 1996-10-31 | Lek Tovarna Farmacevtskih | Process for preparation of alkani salts of clavulanic acid. |
| KR100200242B1 (ko) * | 1995-05-16 | 1999-06-15 | 김충환 | 클라불란산염의 제조 방법 |
| GB9515809D0 (en) * | 1995-08-02 | 1995-10-04 | Smithkline Beecham Plc | Process |
-
1998
- 1998-03-31 DZ DZ980066A patent/DZ2456A1/xx active
- 1998-04-02 PE PE1998000240A patent/PE62499A1/es not_active Application Discontinuation
- 1998-04-02 PL PL336040A patent/PL190943B1/pl unknown
- 1998-04-02 EP EP98922693A patent/EP0970087B1/en not_active Expired - Lifetime
- 1998-04-02 HU HU0003621A patent/HUP0003621A3/hu unknown
- 1998-04-02 AR ARP980101494A patent/AR012307A1/es active IP Right Grant
- 1998-04-02 CA CA002286369A patent/CA2286369C/en not_active Expired - Fee Related
- 1998-04-02 MA MA25026A patent/MA24519A1/fr unknown
- 1998-04-02 AU AU75242/98A patent/AU736305B2/en not_active Ceased
- 1998-04-02 MY MYPI98001467A patent/MY120732A/en unknown
- 1998-04-02 ES ES98922693T patent/ES2294815T3/es not_active Expired - Lifetime
- 1998-04-02 CZ CZ0350099A patent/CZ298785B6/cs not_active IP Right Cessation
- 1998-04-02 TR TR1999/02447T patent/TR199902447T2/tr unknown
- 1998-04-02 BR BR9808467-4A patent/BR9808467A/pt active Search and Examination
- 1998-04-02 US US09/402,231 patent/US6300495B1/en not_active Expired - Fee Related
- 1998-04-02 IL IL13216098A patent/IL132160A/xx not_active IP Right Cessation
- 1998-04-02 NZ NZ337998A patent/NZ337998A/en unknown
- 1998-04-02 DE DE69838747T patent/DE69838747T2/de not_active Expired - Fee Related
- 1998-04-02 JP JP54240798A patent/JP2001521509A/ja not_active Ceased
- 1998-04-02 WO PCT/EP1998/002137 patent/WO1998045300A1/en not_active Ceased
- 1998-04-02 CN CNB988055074A patent/CN1258535C/zh not_active Expired - Fee Related
- 1998-04-02 KR KR1019997009044A patent/KR100540955B1/ko not_active Expired - Fee Related
- 1998-04-03 CO CO98018885A patent/CO4940460A1/es unknown
- 1998-04-03 TW TW087105104A patent/TW444016B/zh not_active IP Right Cessation
-
1999
- 1999-10-01 NO NO19994793A patent/NO325523B1/no unknown
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