TR199903065T2 - Oral uygulamaya yönelik rapamisin formülasyonlari. - Google Patents

Oral uygulamaya yönelik rapamisin formülasyonlari.

Info

Publication number
TR199903065T2
TR199903065T2 TR1999/03065T TR9903065T TR199903065T2 TR 199903065 T2 TR199903065 T2 TR 199903065T2 TR 1999/03065 T TR1999/03065 T TR 1999/03065T TR 9903065 T TR9903065 T TR 9903065T TR 199903065 T2 TR199903065 T2 TR 199903065T2
Authority
TR
Turkey
Prior art keywords
oral administration
rapamycin
rapamycin formulations
formulations
sugar
Prior art date
Application number
TR1999/03065T
Other languages
English (en)
Inventor
Singh Nagi Arwinder
Original Assignee
American Home Products Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corporation filed Critical American Home Products Corporation
Publication of TR199903065T2 publication Critical patent/TR199903065T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Bu bulus bir çekirdek ve bir seker kaplama ihtiva eden rapamisinli kati dozaj ünitesini ortaya koymakta, ve sözü geçen seker kaplama da rapamisin, bir veya daha fazla seker, ve bir veya daha fazla birlestirici madde içermektedir.
TR1999/03065T 1997-06-13 1998-06-11 Oral uygulamaya yönelik rapamisin formülasyonlari. TR199903065T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87496597A 1997-06-13 1997-06-13

Publications (1)

Publication Number Publication Date
TR199903065T2 true TR199903065T2 (tr) 2000-09-21

Family

ID=25364977

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/03065T TR199903065T2 (tr) 1997-06-13 1998-06-11 Oral uygulamaya yönelik rapamisin formülasyonlari.

Country Status (26)

Country Link
EP (1) EP0994697B1 (tr)
JP (1) JP2002504124A (tr)
KR (1) KR20010013650A (tr)
CN (1) CN1133424C (tr)
AR (1) AR012971A1 (tr)
AT (1) ATE283687T1 (tr)
AU (1) AU743584B2 (tr)
BR (1) BR9810746A (tr)
CA (1) CA2293793C (tr)
CZ (1) CZ295276B6 (tr)
DE (1) DE69827947T2 (tr)
DK (1) DK0994697T3 (tr)
ES (1) ES2232948T3 (tr)
HU (1) HUP0003341A3 (tr)
IL (1) IL132986A0 (tr)
NO (1) NO996044L (tr)
NZ (1) NZ501652A (tr)
PL (1) PL337320A1 (tr)
PT (1) PT994697E (tr)
RU (1) RU2184541C2 (tr)
SK (1) SK284472B6 (tr)
TR (1) TR199903065T2 (tr)
TW (1) TW574040B (tr)
UA (1) UA65573C2 (tr)
WO (1) WO1998056358A1 (tr)
ZA (1) ZA985095B (tr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
EP1709974A3 (en) * 2000-06-16 2006-12-06 Wyeth Method of treating cardiovascular disease using rapamycin
US6670355B2 (en) 2000-06-16 2003-12-30 Wyeth Method of treating cardiovascular disease
US20020013335A1 (en) * 2000-06-16 2002-01-31 American Home Products Corporation Method of treating cardiovascular disease
JP4969747B2 (ja) * 2001-01-19 2012-07-04 武田薬品工業株式会社 錠剤フィルムコーティング用組成物
GB0123400D0 (en) 2001-09-28 2001-11-21 Novartis Ag Organic compounds
BR0307544A (pt) 2002-02-01 2004-12-07 Ariad Gene Therapeutics Inc Compostos contendo fósforos, componentes e composição bem como, sua utilização através de métodos de tratamentos
GB0602632D0 (en) * 2006-02-08 2006-03-22 Pliva Istrazivacki Inst D O O Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus
CN102138903B (zh) * 2011-03-17 2012-12-12 苏州特瑞药业有限公司 一种依维莫司固体口服药物组合物
CN110585159B (zh) * 2019-09-12 2021-11-02 杭州华东医药集团新药研究院有限公司 一种含有西罗莫司的片剂
CN116236453A (zh) * 2023-02-08 2023-06-09 江苏和汇医药科技有限公司 一种延长药品释放的糖包衣及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU174057B (hu) * 1976-09-17 1979-10-28 Richter Gedeon Vegyeszet Sostav dlja pokrytij obespechivajuhhij uregulirovannuju otdachy aktivnogo vehhestva biologicheski aktivnykh preparatov i sposob poluchenija takikh preparatov s uregulirovannoj otdachej aktivnogo vehhestva
SG43072A1 (en) * 1991-06-18 1997-10-17 American Home Prod Method of treating adult t-cell leukemia/lymphoma
US5352783A (en) * 1993-06-09 1994-10-04 Merck & Co., Inc. Microbial transformation product having immunosuppressive activity
IL111004A (en) * 1993-09-30 1998-06-15 American Home Prod Oral formulations of rapamycin
US5536729A (en) * 1993-09-30 1996-07-16 American Home Products Corporation Rapamycin formulations for oral administration
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
CA2230748C (en) * 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration

Also Published As

Publication number Publication date
KR20010013650A (ko) 2001-02-26
ATE283687T1 (de) 2004-12-15
AU743584B2 (en) 2002-01-31
AU7836898A (en) 1998-12-30
EP0994697A1 (en) 2000-04-26
DE69827947T2 (de) 2005-04-21
PL337320A1 (en) 2000-08-14
SK171799A3 (en) 2000-07-11
CZ295276B6 (cs) 2005-06-15
RU2184541C2 (ru) 2002-07-10
WO1998056358A1 (en) 1998-12-17
BR9810746A (pt) 2000-09-19
ES2232948T3 (es) 2005-06-01
SK284472B6 (sk) 2005-04-01
UA65573C2 (uk) 2004-04-15
NO996044D0 (no) 1999-12-08
TW574040B (en) 2004-02-01
NZ501652A (en) 2001-09-28
CA2293793C (en) 2006-07-11
CN1259864A (zh) 2000-07-12
IL132986A0 (en) 2001-03-19
HUP0003341A2 (hu) 2001-02-28
NO996044L (no) 1999-12-08
ZA985095B (en) 1999-12-13
EP0994697B1 (en) 2004-12-01
JP2002504124A (ja) 2002-02-05
PT994697E (pt) 2005-02-28
DK0994697T3 (da) 2005-02-14
HUP0003341A3 (en) 2001-03-28
CZ450299A3 (cs) 2000-08-16
CA2293793A1 (en) 1998-12-17
AR012971A1 (es) 2000-11-22
DE69827947D1 (de) 2005-01-05
CN1133424C (zh) 2004-01-07

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