TR199903214T2 - Bir antitümör maddesi ve bir hidroksimik asit türevini ihtiva eden, antitümör etkinligi arttirilmis ve yan etkileri düsürülmüs farmasötik bilesim. - Google Patents
Bir antitümör maddesi ve bir hidroksimik asit türevini ihtiva eden, antitümör etkinligi arttirilmis ve yan etkileri düsürülmüs farmasötik bilesim.Info
- Publication number
- TR199903214T2 TR199903214T2 TR1999/03214T TR9903214T TR199903214T2 TR 199903214 T2 TR199903214 T2 TR 199903214T2 TR 1999/03214 T TR1999/03214 T TR 1999/03214T TR 9903214 T TR9903214 T TR 9903214T TR 199903214 T2 TR199903214 T2 TR 199903214T2
- Authority
- TR
- Turkey
- Prior art keywords
- antithyroid
- side effects
- reduced side
- increased
- pharmaceutical composition
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940043671 antithyroid preparations Drugs 0.000 title 2
- 230000003208 anti-thyroid effect Effects 0.000 title 1
- 239000003200 antithyroid agent Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Bulus, antitümör etkisine sahip olan bir bilinen aktif maddeyi ya da bu maddenin farmasötik açidan kabul edilebilir bir tuzunu ve (I) formülünün bir hidrosimik asit türevini ya da bu türevin bir terapötik açidan yararli asit ilave tuzunu içeren, antitümör etkinligi arttirilmis ya da yan etkileri düsürülmüs farmasötik bilesimlerine iliskindir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9701081A HU9701081D0 (en) | 1997-06-23 | 1997-06-23 | Pharmaceutical composition of antitumoral activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199903214T2 true TR199903214T2 (tr) | 2000-12-21 |
Family
ID=89995266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/03214T TR199903214T2 (tr) | 1997-06-23 | 1998-06-22 | Bir antitümör maddesi ve bir hidroksimik asit türevini ihtiva eden, antitümör etkinligi arttirilmis ve yan etkileri düsürülmüs farmasötik bilesim. |
Country Status (24)
| Country | Link |
|---|---|
| US (4) | US6440998B1 (tr) |
| EP (1) | EP0993304B1 (tr) |
| JP (1) | JP2002508762A (tr) |
| KR (1) | KR20010020496A (tr) |
| CN (1) | CN1127984C (tr) |
| AT (1) | ATE235918T1 (tr) |
| AU (1) | AU735922B2 (tr) |
| BR (1) | BR9810312A (tr) |
| CA (1) | CA2294913C (tr) |
| CZ (1) | CZ298468B6 (tr) |
| DE (1) | DE69812949T2 (tr) |
| DK (1) | DK0993304T3 (tr) |
| ES (1) | ES2195344T3 (tr) |
| HU (1) | HU9701081D0 (tr) |
| IL (1) | IL133508A (tr) |
| NO (1) | NO322206B1 (tr) |
| NZ (1) | NZ502039A (tr) |
| PL (1) | PL191718B1 (tr) |
| PT (1) | PT993304E (tr) |
| RU (2) | RU2254129C2 (tr) |
| SK (1) | SK282877B6 (tr) |
| TR (1) | TR199903214T2 (tr) |
| UA (1) | UA64757C2 (tr) |
| WO (1) | WO1998058676A1 (tr) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6884424B2 (en) * | 1995-12-22 | 2005-04-26 | N-Gene Research Laboratories Inc. | Method for treating the pathological lesions of the skin that develop by ultraviolet radiation of the sunlight |
| US20030158220A1 (en) * | 1997-11-03 | 2003-08-21 | Foss Joseph F. | Use of methylnaltrexone and related compounds to treat chronic opioid use side effects |
| CA2811272C (en) | 2003-04-08 | 2016-12-20 | Progenics Pharmaceuticals, Inc. | Pharmaceutical formulations containing methylnaltrexone |
| FR2878749B1 (fr) * | 2004-12-03 | 2007-12-21 | Aventis Pharma Sa | Combinaisons antitumorales contenant en agent inhibiteur de vegt et du 5fu ou un de ses derives |
| ES2714198T3 (es) * | 2005-03-07 | 2019-05-27 | Univ Chicago | Uso de antagonistas opioideos para atenuar la proliferación y la migración de células endoteliales |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| US8524731B2 (en) * | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| TW200817048A (en) * | 2006-09-08 | 2008-04-16 | Wyeth Corp | Dry powder compound formulations and uses thereof |
| US20080108602A1 (en) * | 2006-11-02 | 2008-05-08 | N-Gene Research Laboratories, Inc. | Prevention of obesity in antipsychotic, antidepressant and antiepileptic medication |
| US7763601B2 (en) * | 2006-11-02 | 2010-07-27 | N-Gene Research Laboratories, Inc. | Prevention and treatment of obesity |
| PL2137191T3 (pl) * | 2007-03-29 | 2016-12-30 | Antagoniści obwodowego receptora opioidowego i ich zastosowania | |
| JP2010522756A (ja) * | 2007-03-29 | 2010-07-08 | プロジェニックス ファーマシューティカルズ,インコーポレーテッド | 結晶形およびその使用 |
| EP2565195B1 (en) * | 2007-03-29 | 2015-05-06 | Wyeth LLC | Peripheral opioid receptor and antagonists and uses thereof |
| WO2009092892A2 (fr) * | 2007-10-30 | 2009-07-30 | Trophos | Nouvelle composition pour traiter les effets secondaires des traitements anticancereux |
| WO2009074835A1 (en) * | 2007-12-10 | 2009-06-18 | N-Gene Research Laboratories Inc. | Dose reduction of a cannabinoid cb1 receptor antagonist in the treatment of overweight or obesity |
| AU2008349873B2 (en) | 2008-02-06 | 2014-02-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone |
| CA2719134C (en) | 2008-03-21 | 2015-06-30 | The University Of Chicago | Treatment with opioid antagonists and mtor inhibitors |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| ITMI20110792A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri appartenenti al genere bifidobacterium per uso nel trattamento della ipercolesterolemia. |
| ITMI20110791A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri in grado di metabolizzare gli ossalati. |
| ITMI20110793A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati. |
| HUP1100445A2 (en) * | 2011-08-17 | 2013-02-28 | Pharma Gene Sa | Pharmaceutical composition |
| HUP1100444A2 (en) | 2011-08-17 | 2013-02-28 | Pharma Gene Sa | Pharmaceutical composition |
| RU2522548C2 (ru) * | 2012-09-26 | 2014-07-20 | Федеральное государственное бюджетное учреждение науки Институт кристаллографии им. А.В. Шубникова Российской академии наук (ИК РАН) | Ингибитор уридинфосфорилаз |
| US9938279B2 (en) * | 2013-04-09 | 2018-04-10 | Energenesis Biomedical Co., Ltd | Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) |
| CN104447746A (zh) * | 2013-09-18 | 2015-03-25 | 华安医学股份有限公司 | 一种活化ampk的化合物及其用途 |
| ITUA20162013A1 (it) | 2016-03-24 | 2017-09-24 | Probiotical Spa | Composizione a base di batteri lattici per il trattamento contemporaneo di infezioni vaginali di origine micotica e batterica. |
| RU2679136C1 (ru) * | 2018-03-13 | 2019-02-06 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" (ФИЦ КНЦ СО РАН, КНЦ СО РАН) | Способ получения препарата на основе взаимодействия цис-диамин(циклобутан-1,1-дикарбоксилат-о,о')платины(ii) с арабиногалактаном |
| HUP1800298A1 (hu) | 2018-08-30 | 2020-05-28 | N Gene Res Laboratories Inc | Gyógyszerkombináció béta-receptor blokkolók hatásának módosítására és a mellékhatások csökkentésére |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4308399A (en) * | 1977-08-30 | 1981-12-29 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same |
| US4599361A (en) * | 1985-09-10 | 1986-07-08 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
| HU207988B (en) * | 1988-10-20 | 1993-07-28 | Biorex Kutato Fejlesztoe Kft | Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components |
| HUT54347A (en) * | 1989-01-10 | 1991-02-28 | Chinoin Gyogyszer Es Vegyeszet | Improved process for producing amidoximes |
| JPH05125029A (ja) * | 1991-11-06 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド化合物又はその塩 |
| RO118000B1 (ro) * | 1993-03-31 | 2002-12-30 | Merck & Co Inc | Metoda pentru tratamentul sida, prevenirea si tratamentul infectiei cu hiv sau inhibarea proteazei hiv si compozitie farmaceutica pentru aplicarea metodei |
| TW381025B (en) * | 1993-08-05 | 2000-02-01 | Hoffmann La Roche | Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor |
| HU9502843D0 (en) * | 1995-09-29 | 1995-11-28 | Livigene Ltd | Pharmaceutical composition |
| UA64716C2 (en) * | 1996-08-09 | 2004-03-15 | Pharmaceuticals for therapy or prevention of illnesses connected with dysfunction of vascular endothelial cells |
-
1997
- 1997-06-23 HU HU9701081A patent/HU9701081D0/hu unknown
-
1998
- 1998-06-22 KR KR1019997012198A patent/KR20010020496A/ko not_active Ceased
- 1998-06-22 DE DE69812949T patent/DE69812949T2/de not_active Expired - Fee Related
- 1998-06-22 RU RU2003101319/15A patent/RU2254129C2/ru not_active IP Right Cessation
- 1998-06-22 DK DK98925873T patent/DK0993304T3/da active
- 1998-06-22 CN CN98807103A patent/CN1127984C/zh not_active Expired - Fee Related
- 1998-06-22 UA UA2000010341A patent/UA64757C2/uk unknown
- 1998-06-22 AT AT98925873T patent/ATE235918T1/de not_active IP Right Cessation
- 1998-06-22 RU RU2000102359/14A patent/RU2214238C2/ru not_active IP Right Cessation
- 1998-06-22 JP JP50404999A patent/JP2002508762A/ja not_active Withdrawn
- 1998-06-22 NZ NZ502039A patent/NZ502039A/xx unknown
- 1998-06-22 AU AU77837/98A patent/AU735922B2/en not_active Ceased
- 1998-06-22 CZ CZ0462599A patent/CZ298468B6/cs not_active IP Right Cessation
- 1998-06-22 PT PT98925873T patent/PT993304E/pt unknown
- 1998-06-22 TR TR1999/03214T patent/TR199903214T2/tr unknown
- 1998-06-22 PL PL337719A patent/PL191718B1/pl unknown
- 1998-06-22 WO PCT/IB1998/000961 patent/WO1998058676A1/en not_active Ceased
- 1998-06-22 EP EP98925873A patent/EP0993304B1/en not_active Expired - Lifetime
- 1998-06-22 ES ES98925873T patent/ES2195344T3/es not_active Expired - Lifetime
- 1998-06-22 US US09/446,064 patent/US6440998B1/en not_active Expired - Fee Related
- 1998-06-22 SK SK1764-99A patent/SK282877B6/sk not_active IP Right Cessation
- 1998-06-22 BR BR9810312-1A patent/BR9810312A/pt active Search and Examination
- 1998-06-22 CA CA002294913A patent/CA2294913C/en not_active Expired - Fee Related
- 1998-06-22 IL IL13350898A patent/IL133508A/xx not_active IP Right Cessation
-
1999
- 1999-12-20 NO NO19996349A patent/NO322206B1/no unknown
-
2002
- 2002-02-28 US US10/084,183 patent/US6656955B2/en not_active Expired - Fee Related
- 2002-02-28 US US10/084,095 patent/US6838469B2/en not_active Expired - Fee Related
- 2002-03-27 US US10/106,227 patent/US6720337B2/en not_active Expired - Fee Related
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