PT930877E - D-metionina para reduzir a toxicidade de compostos antitumorais contendo platina - Google Patents

D-metionina para reduzir a toxicidade de compostos antitumorais contendo platina

Info

Publication number: PT930877E
Authority: PT; Portugal
Prior art keywords: methionine; toxicity; reduce; platinum; compounds containing
Prior art date: 1996-10-03

Application number

PT97911634T

Other languages

English (en)

Inventor

Kathleen C M Campbell

Original Assignee

Univ Southern Illinois

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-03

Filing date

1997-10-02

Publication date

2006-09-29

1997-10-02 Application filed by Univ Southern Illinois filed Critical Univ Southern Illinois

2006-09-29 Publication of PT930877E publication Critical patent/PT930877E/pt

Links

BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title abstract 6
229910052697 platinum Inorganic materials 0.000 title abstract 3
FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 title abstract 2
230000000259 anti-tumor effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
230000001988 toxicity Effects 0.000 title 1
231100000419 toxicity Toxicity 0.000 title 1
239000002246 antineoplastic agent Substances 0.000 abstract 2
229940127089 cytotoxic agent Drugs 0.000 abstract 2
201000004384 Alopecia Diseases 0.000 abstract 1
229930182818 D-methionine Natural products 0.000 abstract 1
206010059024 Gastrointestinal toxicity Diseases 0.000 abstract 1
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
206010029350 Neurotoxicity Diseases 0.000 abstract 1
206010044221 Toxic encephalopathy Diseases 0.000 abstract 1
231100000360 alopecia Toxicity 0.000 abstract 1
229960004316 cisplatin Drugs 0.000 abstract 1
DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 abstract 1
231100000414 gastrointestinal toxicity Toxicity 0.000 abstract 1
229930182817 methionine Natural products 0.000 abstract 1
231100000228 neurotoxicity Toxicity 0.000 abstract 1
230000007135 neurotoxicity Effects 0.000 abstract 1
239000003223 protective agent Substances 0.000 abstract 1
230000004083 survival effect Effects 0.000 abstract 1
230000004580 weight loss Effects 0.000 abstract 1
208000016261 weight loss Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Inorganic Chemistry (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PT97911634T 1996-10-03 1997-10-02 D-metionina para reduzir a toxicidade de compostos antitumorais contendo platina PT930877E (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2775096P	1996-10-03	1996-10-03

Publications (1)

Publication Number	Publication Date
PT930877E true PT930877E (pt)	2006-09-29

Family

ID=21839569

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97911634T PT930877E (pt)	1996-10-03	1997-10-02	D-metionina para reduzir a toxicidade de compostos antitumorais contendo platina

Country Status (10)

Country	Link
EP (1)	EP0930877B1 (pt)
JP (1)	JP4260889B2 (pt)
AT (1)	ATE323475T1 (pt)
AU (1)	AU726392B2 (pt)
CA (1)	CA2265983C (pt)
DE (1)	DE69735722T2 (pt)
DK (1)	DK0930877T3 (pt)
ES (1)	ES2263172T3 (pt)
PT (1)	PT930877E (pt)
WO (1)	WO1998014182A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7071230B2 (en)	1997-10-02	2006-07-04	Board Of Trustees Of Southern Illinois University	Therapeutic use of D-methionine to reduce the toxicity of noise
CA2461219A1 (en) *	2001-09-24	2003-04-03	Tosk, Inc.	Reduced toxicity cisplatin formulations and methods for using the same
US20050090551A1 (en) *	2003-10-27	2005-04-28	Board Of Trustees Of Southern Illinois University	Therapeutic use of methionine for the treatment or prevention of mucositis
USRE48077E1 (en)	2013-02-28	2020-07-07	Anida Pharma Inc.	Methods of treating ototoxicity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH06192109A (ja) *	1992-09-04	1994-07-12	Fuji Kagaku Kogyo Kk	抗腫瘍効果増強剤

1997
- 1997-10-02 JP JP51697398A patent/JP4260889B2/ja not_active Expired - Fee Related
- 1997-10-02 WO PCT/US1997/018114 patent/WO1998014182A1/en not_active Ceased
- 1997-10-02 EP EP97911634A patent/EP0930877B1/en not_active Expired - Lifetime
- 1997-10-02 AU AU48957/97A patent/AU726392B2/en not_active Ceased
- 1997-10-02 ES ES97911634T patent/ES2263172T3/es not_active Expired - Lifetime
- 1997-10-02 CA CA002265983A patent/CA2265983C/en not_active Expired - Fee Related
- 1997-10-02 PT PT97911634T patent/PT930877E/pt unknown
- 1997-10-02 DE DE69735722T patent/DE69735722T2/de not_active Expired - Lifetime
- 1997-10-02 AT AT97911634T patent/ATE323475T1/de not_active IP Right Cessation
- 1997-10-02 DK DK97911634T patent/DK0930877T3/da active

Also Published As

Publication number	Publication date
JP4260889B2 (ja)	2009-04-30
ATE323475T1 (de)	2006-05-15
AU4895797A (en)	1998-04-24
DE69735722D1 (de)	2006-05-24
DE69735722T2 (de)	2007-04-12
DK0930877T3 (da)	2006-08-21
AU726392B2 (en)	2000-11-09
EP0930877A1 (en)	1999-07-28
CA2265983A1 (en)	1998-04-09
WO1998014182A1 (en)	1998-04-09
JP2001501626A (ja)	2001-02-06
CA2265983C (en)	2003-12-23
ES2263172T3 (es)	2006-12-01
EP0930877B1 (en)	2006-04-19

Similar Documents

Publication	Publication Date	Title
DE69815872D1 (de)	2003-07-31	Verwendung von d-methionin zur verminderung der toxizität von ototoxischen arzneimitteln und geräusch
CA2294247A1 (en)	1999-01-14	Antioxidant enhancement of therapy for hyperproliferative conditions
CY2473B1 (en)	2005-06-03	New phenanthridines.
EP1478406A4 (en)	2006-01-11	COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS AND OTHER MATERIALS AND METHOD FOR THE PRODUCTION AND USE THEREOF
DK0612248T3 (da)	2003-12-08	Præparat, der indeholder cisplatin og topotecan som antitumormiddel
MY117526A (en)	2004-07-31	N-(3-benzofuranyl)urea-derivatives
TR199903214T2 (xx)	2000-12-21	Bir antit�m�r maddesi ve bir hidroksimik asit t�revini ihtiva eden, antit�m�r etkinli�i artt�r�lm�� ve yan etkileri d��r�lm�� farmas�tik bile�im.
EP0211354A3 (en)	1988-02-10	Nucleosides and their use as antineoplastic agents
TR199901904T2 (xx)	1999-10-21	3-piridil enantiyomerleri ve bunlar�n analjezik olarak kullan�lmas�.
IL133824A0 (en)	2001-04-30	Tetrazole derivatives, medicaments containing same and use thereof
EP0902789A4 (pt)	1999-04-14
ATE413179T1 (de)	2008-11-15	Therapeutische verwendungen von steroiden bei blutzellmangelzustaenden
MX9400434A (es)	1994-07-29	Potenciamiento de temozolomida en celulas de tumores humanos.
EP2020237A3 (en)	2009-02-11	Ceramide and chemotherapeutic agents for inducing cell death
DK1161228T3 (da)	2003-11-24	Præparat omfattende isoquercetin og ascorbinsyre i en sustained release-form
DK1187611T3 (da)	2004-10-11	Oftalmiske histaminholdige sammensætninger og anvendelse deraf
WO2005039554A3 (en)	2005-12-15	Therapeutic use of methionine for the treatment or prevention of mucositis
DK0930877T3 (da)	2006-08-21	D-methionin til formindskelse af toksiciteten af platinholdige antitumorforbindelser
NZ335125A (en)	1999-11-29	Carriers containing an etherlipid/complementarily shape lipid combination and therapeutic uses thereof
MX9700359A (es)	1997-04-30	Derivados terpenoides utiles como agentes antitumorales.
CA2458856A1 (en)	2003-03-06	Improved therapeutic protocols
ES2105959A1 (es)	1997-10-16	Derivados de 1,4-dioxido de quinoxalina, procedimiento de preparacion y de utilizacion.
GB9710698D0 (en)	1997-07-16	Composition
MX9701606A (es)	1998-04-30	Terapia de combinacion para evitar la perdida osea-progesterona y agonistas de estrogeno.
DE60203895D1 (de)	2005-06-02	Verwendung von n-acetyl-d-glucosamin bei der herstellung eines arzneimittels zur unterdrückung der nebenwirkungen von strahlentherapie und chemotherapie