TR200000563T2 - Atorvastatin ve bir antihipertensif vasıta içeren bileşim terapisi. - Google Patents
Atorvastatin ve bir antihipertensif vasıta içeren bileşim terapisi.Info
- Publication number
- TR200000563T2 TR200000563T2 TR2000/00563T TR200000563T TR200000563T2 TR 200000563 T2 TR200000563 T2 TR 200000563T2 TR 2000/00563 T TR2000/00563 T TR 2000/00563T TR 200000563 T TR200000563 T TR 200000563T TR 200000563 T2 TR200000563 T2 TR 200000563T2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- atorvastatin
- heart disease
- subjects
- antihypertensive
- Prior art date
Links
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 title abstract 3
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 title abstract 3
- 229960005370 atorvastatin Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 208000019622 heart disease Diseases 0.000 abstract 3
- 206010002383 Angina Pectoris Diseases 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 2
- 230000000996 additive effect Effects 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000002195 synergetic effect Effects 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000032023 Signs and Symptoms Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008196 pharmacological composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Pyrrole Compounds (AREA)
Abstract
Bu bulus, atorvastatin'in farmakolojik bilesimleri veya bunun farmakolojik olarak uygun bir tuzuyla ve antihipertensif vasitalarla, bu gibi bilesimleri içeren donanimlarla ve anjina pektoris, aterosklerosis, hipertansiyon ve hiperlipidemia' nin birlikte bulundugu durumlardan rahatsizlik çeken öznelerin tedavisinde ve insanlar da dahil olmak üzere kalp hastaliklariyla ilgili risk tasiyan öznelerin tedavisinde bu gibi bilesimleri kullanma metotlariyla ilgilidir. Ayrica bu bulus, atorvastatin veya bunun farmakolojik olarak uygun bir tuzu ve antihipertensif vasitalarin olusturdugu katki ve sinerjetik bilesimlerle ilgilidir ki bu katki ve sinerjetik bilesimler; anjina pektoris, aterosklerosis, hipertansiyon ve hiperlipidemia' nin birlikte bulundugu durumlardan rahatsizlik çeken öznelerin tedavisi ve insanlar da dahil olmak üzere kalp hastaliklariyla ilgili risk tasidigina dair semptomlar ve belirtiler gösteren öznelerin tedavisi için yararlidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5727697P | 1997-08-29 | 1997-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200000563T2 true TR200000563T2 (tr) | 2000-07-21 |
Family
ID=22009602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/00563T TR200000563T2 (tr) | 1997-08-29 | 1998-08-11 | Atorvastatin ve bir antihipertensif vasıta içeren bileşim terapisi. |
Country Status (41)
| Country | Link |
|---|---|
| US (2) | US20020099046A1 (tr) |
| EP (1) | EP1009400B1 (tr) |
| JP (2) | JP2001514223A (tr) |
| KR (3) | KR20010022477A (tr) |
| CN (3) | CN1268053A (tr) |
| AP (1) | AP1191A (tr) |
| AR (1) | AR016399A1 (tr) |
| AT (1) | ATE285767T1 (tr) |
| AU (1) | AU740424B2 (tr) |
| BG (1) | BG64724B1 (tr) |
| BR (1) | BR9811556A (tr) |
| CA (1) | CA2296723A1 (tr) |
| CO (1) | CO4970724A1 (tr) |
| DE (1) | DE69828413T2 (tr) |
| DZ (1) | DZ2595A1 (tr) |
| EA (1) | EA200000012A1 (tr) |
| EG (1) | EG24678A (tr) |
| ES (1) | ES2234134T3 (tr) |
| GT (1) | GT199800126A (tr) |
| HR (1) | HRP980474A2 (tr) |
| HU (1) | HUP0004318A3 (tr) |
| ID (1) | ID24118A (tr) |
| IL (2) | IL133962A0 (tr) |
| IS (1) | IS5341A (tr) |
| MA (1) | MA26536A1 (tr) |
| MY (1) | MY121008A (tr) |
| NO (1) | NO323987B1 (tr) |
| NZ (2) | NZ530630A (tr) |
| OA (1) | OA11291A (tr) |
| PA (1) | PA8457901A1 (tr) |
| PE (1) | PE107099A1 (tr) |
| PL (1) | PL339091A1 (tr) |
| PT (1) | PT1009400E (tr) |
| SA (1) | SA98190603B1 (tr) |
| SK (1) | SK1432000A3 (tr) |
| TN (1) | TNSN98155A1 (tr) |
| TR (1) | TR200000563T2 (tr) |
| UY (1) | UY25155A1 (tr) |
| WO (1) | WO1999011260A1 (tr) |
| YU (1) | YU2000A (tr) |
| ZA (1) | ZA987839B (tr) |
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| AUPO203996A0 (en) | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
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| AU3103800A (en) | 1998-12-23 | 2000-07-31 | G.D. Searle Llc | Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acidderivatives for cardiovascular indications |
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| JP7474738B2 (ja) * | 2018-07-26 | 2024-04-25 | ザ ジョージ インスティテュート フォー グローバル ヘルス | 高血圧症の処置のための組成物 |
| CN112826937B (zh) * | 2021-03-25 | 2022-03-22 | 山东大学齐鲁医院 | 艾地苯醌与他汀类药物联用在防治动脉粥样硬化中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4681893A (en) * | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
| FI94339C (fi) * | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| US5447922A (en) * | 1994-08-24 | 1995-09-05 | Bristol-Myers Squibb Company | α-phosphonosulfinic squalene synthetase inhibitors |
| NZ286920A (en) * | 1995-07-03 | 1997-06-24 | Sankyo Co | Use of combination of hmg-coa reductase inhibitors and of insulin sensitizers for the prevention/treatment of arteriosclerosis or xanthoma |
| CZ127198A3 (cs) * | 1995-11-02 | 1998-12-16 | Warner-Lambert Company | Způsob regulace koncentrace lipidů a farmaceutická kompozice pro tento způsob |
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1998
- 1998-08-07 GT GT199800126A patent/GT199800126A/es unknown
- 1998-08-11 AU AU84589/98A patent/AU740424B2/en not_active Ceased
- 1998-08-11 KR KR1020007001062A patent/KR20010022477A/ko not_active Ceased
- 1998-08-11 TR TR2000/00563T patent/TR200000563T2/tr unknown
- 1998-08-11 HU HU0004318A patent/HUP0004318A3/hu unknown
- 1998-08-11 AT AT98935250T patent/ATE285767T1/de not_active IP Right Cessation
- 1998-08-11 ES ES98935250T patent/ES2234134T3/es not_active Expired - Lifetime
- 1998-08-11 DE DE69828413T patent/DE69828413T2/de not_active Expired - Fee Related
- 1998-08-11 CN CN98808463A patent/CN1268053A/zh active Pending
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- 1998-08-11 EA EA200000012A patent/EA200000012A1/ru unknown
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- 1998-08-11 EP EP98935250A patent/EP1009400B1/en not_active Expired - Lifetime
- 1998-08-11 ID IDW20000196A patent/ID24118A/id unknown
- 1998-08-11 WO PCT/IB1998/001230 patent/WO1999011260A1/en not_active Ceased
- 1998-08-11 KR KR10-2004-7019432A patent/KR20040106591A/ko not_active Ceased
- 1998-08-11 CN CNA031430929A patent/CN1473566A/zh active Pending
- 1998-08-11 IL IL13396298A patent/IL133962A0/xx not_active IP Right Cessation
- 1998-08-11 CA CA002296723A patent/CA2296723A1/en not_active Abandoned
- 1998-08-11 JP JP2000508363A patent/JP2001514223A/ja not_active Withdrawn
- 1998-08-11 CN CNA031430937A patent/CN1473567A/zh active Pending
- 1998-08-11 KR KR10-2003-7000672A patent/KR20030015394A/ko not_active Ceased
- 1998-08-11 NZ NZ502280A patent/NZ502280A/xx unknown
- 1998-08-11 BR BR9811556-1A patent/BR9811556A/pt not_active Application Discontinuation
- 1998-08-11 SK SK143-2000A patent/SK1432000A3/sk unknown
- 1998-08-17 PA PA19988457901A patent/PA8457901A1/es unknown
- 1998-08-24 PE PE1998000769A patent/PE107099A1/es not_active Application Discontinuation
- 1998-08-26 MA MA25228A patent/MA26536A1/fr unknown
- 1998-08-26 UY UY25155A patent/UY25155A1/es not_active Application Discontinuation
- 1998-08-26 DZ DZ980205A patent/DZ2595A1/xx active
- 1998-08-26 TN TNTNSN98155A patent/TNSN98155A1/fr unknown
- 1998-08-27 MY MYPI98003941A patent/MY121008A/en unknown
- 1998-08-27 AR ARP980104287A patent/AR016399A1/es unknown
- 1998-08-27 AP APAP/P/1998/001332A patent/AP1191A/en active
- 1998-08-27 EG EG102598A patent/EG24678A/xx active
- 1998-08-27 CO CO98049139A patent/CO4970724A1/es unknown
- 1998-08-28 HR HR60/057,276A patent/HRP980474A2/hr not_active Application Discontinuation
- 1998-08-28 ZA ZA9807839A patent/ZA987839B/xx unknown
- 1998-09-30 SA SA98190603A patent/SA98190603B1/ar unknown
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2000
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- 2000-01-13 BG BG104075A patent/BG64724B1/bg unknown
- 2000-01-14 IS IS5341A patent/IS5341A/is unknown
- 2000-02-18 OA OA1200000040A patent/OA11291A/en unknown
- 2000-02-28 NO NO20000996A patent/NO323987B1/no unknown
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2001
- 2001-10-23 US US10/045,329 patent/US20020099046A1/en not_active Abandoned
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2003
- 2003-05-19 US US10/442,285 patent/US20030199492A1/en not_active Abandoned
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2004
- 2004-07-22 JP JP2004214382A patent/JP2005041875A/ja not_active Withdrawn
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