TR200003101T2 - Levosimendan ve aljinik asit içeren kararlı kompozisyonlar - Google Patents
Levosimendan ve aljinik asit içeren kararlı kompozisyonlarInfo
- Publication number
- TR200003101T2 TR200003101T2 TR2000/03101T TR200003101T TR200003101T2 TR 200003101 T2 TR200003101 T2 TR 200003101T2 TR 2000/03101 T TR2000/03101 T TR 2000/03101T TR 200003101 T TR200003101 T TR 200003101T TR 200003101 T2 TR200003101 T2 TR 200003101T2
- Authority
- TR
- Turkey
- Prior art keywords
- alginic acid
- levosimendan
- compositions containing
- stable compositions
- containing levosimendan
- Prior art date
Links
- WHXMKTBCFHIYNQ-SECBINFHSA-N levosimendan Chemical compound C[C@@H]1CC(=O)NN=C1C1=CC=C(NN=C(C#N)C#N)C=C1 WHXMKTBCFHIYNQ-SECBINFHSA-N 0.000 title abstract 4
- 229960000692 levosimendan Drugs 0.000 title abstract 4
- 229960001126 alginic acid Drugs 0.000 title abstract 2
- 235000010443 alginic acid Nutrition 0.000 title abstract 2
- 229920000615 alginic acid Polymers 0.000 title abstract 2
- 239000000783 alginic acid Substances 0.000 title abstract 2
- 150000004781 alginic acids Chemical class 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000036772 blood pressure Effects 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Inorganic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Jellies, Jams, And Syrups (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Bu son bulus levosimendanin kompozisyonlardaki kararliliginin arttirilmasi için aljinik asit içeren levosimendanin farmasötik kompozisyonlari ile ilgilidir. Levosimendan kan basimina ait kalp bozuklugunun tedavisinde faydalidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI980902A FI980902A7 (fi) | 1998-04-23 | 1998-04-23 | Levosimendaanin stabiileja koostumuksia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200003101T2 true TR200003101T2 (tr) | 2001-01-22 |
Family
ID=8551576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/03101T TR200003101T2 (tr) | 1998-04-23 | 1999-04-23 | Levosimendan ve aljinik asit içeren kararlı kompozisyonlar |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6531458B1 (tr) |
| EP (1) | EP1079834B1 (tr) |
| JP (1) | JP4475809B2 (tr) |
| KR (1) | KR100590622B1 (tr) |
| CN (1) | CN1165309C (tr) |
| AT (1) | ATE231395T1 (tr) |
| AU (1) | AU756338B2 (tr) |
| BG (1) | BG64766B1 (tr) |
| BR (1) | BR9909867A (tr) |
| CA (1) | CA2329232C (tr) |
| CZ (1) | CZ290911B6 (tr) |
| DE (1) | DE69905034T2 (tr) |
| DK (1) | DK1079834T3 (tr) |
| EA (1) | EA002428B1 (tr) |
| EE (1) | EE04143B1 (tr) |
| ES (1) | ES2191426T3 (tr) |
| FI (1) | FI980902A7 (tr) |
| GE (1) | GEP20032942B (tr) |
| HR (1) | HRP20000703B1 (tr) |
| HU (1) | HUP0105446A3 (tr) |
| ID (1) | ID26650A (tr) |
| IL (2) | IL138950A0 (tr) |
| MX (1) | MXPA00010368A (tr) |
| NO (1) | NO318575B1 (tr) |
| NZ (1) | NZ507455A (tr) |
| PL (1) | PL192274B1 (tr) |
| PT (1) | PT1079834E (tr) |
| RS (1) | RS49955B (tr) |
| SK (1) | SK284600B6 (tr) |
| TR (1) | TR200003101T2 (tr) |
| WO (1) | WO1999055337A1 (tr) |
| ZA (1) | ZA200005630B (tr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI980901A7 (fi) * | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaania säädellysti vapauttavia oraalisia koostumuksia |
| FI109659B (fi) * | 1999-09-10 | 2002-09-30 | Orion Yhtymae Oyj | Levosimendaanin farmaseuttisia liuoksia |
| FI20010233A0 (fi) * | 2001-02-08 | 2001-02-08 | Orion Corp | Menetelmä sydämen vajaatoiminnan hoitoon |
| WO2002064120A1 (fr) * | 2001-02-13 | 2002-08-22 | Taisho Pharmaceutical Co., Ltd. | Preparations de gel a usage interne |
| CA2599575A1 (en) * | 2005-03-14 | 2006-09-21 | Orion Corporation | A combination treatment for enhancing diuresis |
| SI3370693T1 (sl) * | 2015-11-06 | 2020-07-31 | Carinopharm Gmbh | Izboljšane formulacije levosimendana za intravensko dajanje kot infuzija ali injekcija in infuzijski koncentrat |
| CA3161960A1 (en) | 2019-12-16 | 2021-06-24 | Tenax Therapeutics, Inc. | Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1509866A (en) | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
| PT76448B (en) * | 1982-04-05 | 1986-03-20 | Merck Sharp & Dohme | Process for preparing stabilization of unstable drugs or food supplements containing antibiotics mainly ephrotomycin |
| EP0123291A2 (en) | 1983-04-20 | 1984-10-31 | Kyowa Hakko Kogyo Co., Ltd. | Method for stabilizing interferon |
| US4906630A (en) * | 1985-11-22 | 1990-03-06 | Rorer Pharmaceutical Corporation | Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds |
| US4716042A (en) * | 1986-06-16 | 1987-12-29 | American Home Products Corporation | Stabilized coated aspirin tablets |
| GB8903130D0 (en) | 1989-02-11 | 1989-03-30 | Orion Yhtymae Oy | Substituted pyridazinones |
| GB2251615B (en) * | 1991-01-03 | 1995-02-08 | Orion Yhtymae Oy | (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile |
| GB2266841A (en) | 1992-05-06 | 1993-11-17 | Orion Yhtymae Oy | Compounds for use as anti-ischemic medicaments |
| GB9614098D0 (en) * | 1996-07-05 | 1996-09-04 | Orion Yhtymae Oy | Transdermal delivery of levosimendan |
| FI973804A7 (fi) * | 1997-09-26 | 1999-03-27 | Orion Yhtymae Oy | Levosimendaanin oraalisia koostumuksia |
-
1998
- 1998-04-23 FI FI980902A patent/FI980902A7/fi unknown
-
1999
- 1999-04-23 IL IL13895099A patent/IL138950A0/xx active IP Right Grant
- 1999-04-23 NZ NZ507455A patent/NZ507455A/en unknown
- 1999-04-23 TR TR2000/03101T patent/TR200003101T2/tr unknown
- 1999-04-23 EE EEP200000616A patent/EE04143B1/xx not_active IP Right Cessation
- 1999-04-23 DE DE69905034T patent/DE69905034T2/de not_active Expired - Lifetime
- 1999-04-23 CN CNB998053805A patent/CN1165309C/zh not_active Expired - Fee Related
- 1999-04-23 ES ES99916943T patent/ES2191426T3/es not_active Expired - Lifetime
- 1999-04-23 EP EP99916943A patent/EP1079834B1/en not_active Expired - Lifetime
- 1999-04-23 DK DK99916943T patent/DK1079834T3/da active
- 1999-04-23 AT AT99916943T patent/ATE231395T1/de not_active IP Right Cessation
- 1999-04-23 JP JP2000545535A patent/JP4475809B2/ja not_active Expired - Lifetime
- 1999-04-23 CA CA002329232A patent/CA2329232C/en not_active Expired - Fee Related
- 1999-04-23 PT PT99916943T patent/PT1079834E/pt unknown
- 1999-04-23 BR BR9909867-9A patent/BR9909867A/pt not_active Application Discontinuation
- 1999-04-23 GE GEAP19995638A patent/GEP20032942B/en unknown
- 1999-04-23 HR HR20000703A patent/HRP20000703B1/xx not_active IP Right Cessation
- 1999-04-23 HU HU0105446A patent/HUP0105446A3/hu unknown
- 1999-04-23 EA EA200001097A patent/EA002428B1/ru not_active IP Right Cessation
- 1999-04-23 KR KR1020007011789A patent/KR100590622B1/ko not_active Expired - Fee Related
- 1999-04-23 WO PCT/FI1999/000331 patent/WO1999055337A1/en not_active Ceased
- 1999-04-23 PL PL343722A patent/PL192274B1/pl not_active IP Right Cessation
- 1999-04-23 US US09/673,793 patent/US6531458B1/en not_active Expired - Fee Related
- 1999-04-23 RS YUP-640/00A patent/RS49955B/sr unknown
- 1999-04-23 SK SK1555-2000A patent/SK284600B6/sk not_active IP Right Cessation
- 1999-04-23 MX MXPA00010368A patent/MXPA00010368A/es active IP Right Grant
- 1999-04-23 CZ CZ20003779A patent/CZ290911B6/cs not_active IP Right Cessation
- 1999-04-23 AU AU35248/99A patent/AU756338B2/en not_active Ceased
- 1999-04-23 ID IDW20002368A patent/ID26650A/id unknown
-
2000
- 2000-10-11 IL IL138950A patent/IL138950A/en not_active IP Right Cessation
- 2000-10-12 ZA ZA200005630A patent/ZA200005630B/en unknown
- 2000-10-20 NO NO20005312A patent/NO318575B1/no not_active IP Right Cessation
- 2000-11-17 BG BG104958A patent/BG64766B1/bg unknown
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