TR200102008T2 - Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı. - Google Patents
Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı.Info
- Publication number
- TR200102008T2 TR200102008T2 TR2001/02008T TR200102008T TR200102008T2 TR 200102008 T2 TR200102008 T2 TR 200102008T2 TR 2001/02008 T TR2001/02008 T TR 2001/02008T TR 200102008 T TR200102008 T TR 200102008T TR 200102008 T2 TR200102008 T2 TR 200102008T2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- cerebral ischemia
- prophylaxis
- pyridine derivatives
- formula
- Prior art date
Links
- 201000006474 Brain Ischemia Diseases 0.000 title abstract 2
- 206010008120 Cerebral ischaemia Diseases 0.000 title abstract 2
- 206010008118 cerebral infarction Diseases 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bulus, ikame ajanlarinin açiklamada tanimlandigi gibi oldugu formül (I)'in pirimidin türevlerinin ve bunlarin fizyolojik olarak uygun tuzlarinin serebral iskeminin ve inmelerin önlenmesi ve tedavi edilmesi amaciyla ilaçlarin üretiminde kullanimi ile ilgilidir. (FORMÜL VAR)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19900545A DE19900545A1 (de) | 1999-01-11 | 1999-01-11 | Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200102008T2 true TR200102008T2 (tr) | 2001-12-21 |
Family
ID=7893836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/02008T TR200102008T2 (tr) | 1999-01-11 | 1999-12-24 | Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6387912B1 (tr) |
| EP (1) | EP1140096A1 (tr) |
| JP (1) | JP2002534465A (tr) |
| KR (1) | KR20010101442A (tr) |
| CN (1) | CN1334732A (tr) |
| AU (1) | AU2433800A (tr) |
| BG (1) | BG105689A (tr) |
| BR (1) | BR9916887A (tr) |
| CA (1) | CA2359253A1 (tr) |
| CZ (2) | CZ20012484A3 (tr) |
| DE (1) | DE19900545A1 (tr) |
| HK (1) | HK1042649A1 (tr) |
| HU (1) | HUP0201149A3 (tr) |
| ID (1) | ID30022A (tr) |
| IL (1) | IL144146A0 (tr) |
| MX (1) | MXPA01006967A (tr) |
| MY (1) | MY133107A (tr) |
| NO (1) | NO20013409L (tr) |
| NZ (1) | NZ512767A (tr) |
| PL (1) | PL348920A1 (tr) |
| SK (1) | SK9692001A3 (tr) |
| TR (1) | TR200102008T2 (tr) |
| WO (1) | WO2000041695A1 (tr) |
| ZA (1) | ZA200105475B (tr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19900673A1 (de) | 1999-01-11 | 2000-07-13 | Basf Ag | Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen |
| US6988199B2 (en) * | 2000-07-07 | 2006-01-17 | Message Secure | Secure and reliable document delivery |
| JP4548882B2 (ja) * | 1999-11-30 | 2010-09-22 | 興和創薬株式会社 | 4,5,6,7−テトラヒドロチエノ〔2,3−c〕ピリジン化合物 |
| DE10031390A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
| DE10031389A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
| DE10259382A1 (de) * | 2002-12-18 | 2004-07-01 | Abbott Gmbh & Co. Kg | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung |
| CA2685753A1 (en) * | 2007-05-09 | 2008-11-20 | Neuromed Pharmaceuticals Ltd. | Bicyclic pyrimidine derivatives as calcium channel blockers |
| US8927718B2 (en) | 2009-08-26 | 2015-01-06 | Takeda Pharmaceutical Company Limited | Fused heterocyclic ring derivative and use thereof |
| US11691971B2 (en) | 2020-06-19 | 2023-07-04 | Incyte Corporation | Naphthyridinone compounds as JAK2 V617F inhibitors |
| WO2021257863A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Pyrrolotriazine compounds as jak2 v617f inhibitors |
| WO2022006456A1 (en) | 2020-07-02 | 2022-01-06 | Incyte Corporation | Tricyclic pyridone compounds as jak2 v617f inhibitors |
| BR112023000047A2 (pt) | 2020-07-02 | 2023-03-14 | Incyte Corp | Compostos de ureia tricíclicos como inibidores da v617f da jak2 |
| US11661422B2 (en) | 2020-08-27 | 2023-05-30 | Incyte Corporation | Tricyclic urea compounds as JAK2 V617F inhibitors |
| WO2022140231A1 (en) | 2020-12-21 | 2022-06-30 | Incyte Corporation | Deazaguaine compounds as jak2 v617f inhibitors |
| AR125273A1 (es) | 2021-02-25 | 2023-07-05 | Incyte Corp | Lactamas espirocíclicas como inhibidores de jak2 v617f |
| KR20240163688A (ko) | 2022-03-17 | 2024-11-19 | 인사이트 코포레이션 | Jak2 v617f 억제제로서의 삼환계 우레아 화합물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4670560A (en) | 1986-04-28 | 1987-06-02 | Ortho Pharmaceutical Corporation | Thienopyrimidine-2,4-dione derivatives and intermediates thereof |
| DE19636769A1 (de) | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724979A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724980A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
-
1999
- 1999-01-11 DE DE19900545A patent/DE19900545A1/de not_active Withdrawn
- 1999-12-22 CZ CZ20012484A patent/CZ20012484A3/cs unknown
- 1999-12-22 ID IDW00200101717A patent/ID30022A/id unknown
- 1999-12-24 TR TR2001/02008T patent/TR200102008T2/tr unknown
- 1999-12-24 WO PCT/EP1999/010369 patent/WO2000041695A1/de not_active Ceased
- 1999-12-24 PL PL99348920A patent/PL348920A1/xx not_active Application Discontinuation
- 1999-12-24 KR KR1020017008692A patent/KR20010101442A/ko not_active Ceased
- 1999-12-24 CZ CZ20012485A patent/CZ20012485A3/cs unknown
- 1999-12-24 NZ NZ512767A patent/NZ512767A/en unknown
- 1999-12-24 BR BR9916887-1A patent/BR9916887A/pt not_active IP Right Cessation
- 1999-12-24 HK HK02104075.8A patent/HK1042649A1/zh unknown
- 1999-12-24 AU AU24338/00A patent/AU2433800A/en not_active Abandoned
- 1999-12-24 US US09/889,162 patent/US6387912B1/en not_active Expired - Fee Related
- 1999-12-24 CN CN99816172A patent/CN1334732A/zh active Pending
- 1999-12-24 JP JP2000593306A patent/JP2002534465A/ja active Pending
- 1999-12-24 MX MXPA01006967A patent/MXPA01006967A/es not_active Application Discontinuation
- 1999-12-24 HU HU0201149A patent/HUP0201149A3/hu unknown
- 1999-12-24 SK SK969-2001A patent/SK9692001A3/sk unknown
- 1999-12-24 IL IL14414699A patent/IL144146A0/xx unknown
- 1999-12-24 CA CA002359253A patent/CA2359253A1/en not_active Abandoned
- 1999-12-24 EP EP99967980A patent/EP1140096A1/de not_active Withdrawn
-
2000
- 2000-01-11 MY MYPI20000084A patent/MY133107A/en unknown
-
2001
- 2001-07-03 ZA ZA200105475A patent/ZA200105475B/en unknown
- 2001-07-10 NO NO20013409A patent/NO20013409L/no not_active Application Discontinuation
- 2001-07-10 BG BG105689A patent/BG105689A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20012485A3 (cs) | 2002-04-17 |
| PL348920A1 (en) | 2002-06-17 |
| NZ512767A (en) | 2003-05-30 |
| BR9916887A (pt) | 2001-11-20 |
| NO20013409D0 (no) | 2001-07-10 |
| NO20013409L (no) | 2001-08-30 |
| US6387912B1 (en) | 2002-05-14 |
| BG105689A (en) | 2002-02-28 |
| MY133107A (en) | 2007-10-31 |
| JP2002534465A (ja) | 2002-10-15 |
| MXPA01006967A (es) | 2002-04-10 |
| SK9692001A3 (en) | 2002-05-09 |
| HK1042649A1 (zh) | 2002-08-23 |
| KR20010101442A (ko) | 2001-11-14 |
| AU2433800A (en) | 2000-08-01 |
| WO2000041695A1 (de) | 2000-07-20 |
| EP1140096A1 (de) | 2001-10-10 |
| CN1334732A (zh) | 2002-02-06 |
| CA2359253A1 (en) | 2000-07-20 |
| IL144146A0 (en) | 2002-05-23 |
| HUP0201149A2 (hu) | 2002-07-29 |
| ID30022A (id) | 2001-11-01 |
| HUP0201149A3 (en) | 2003-07-28 |
| CZ20012484A3 (cs) | 2002-05-15 |
| DE19900545A1 (de) | 2000-07-13 |
| ZA200105475B (en) | 2002-10-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA03005464A (es) | Agentes antivirales. | |
| MY139302A (en) | Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof | |
| MA27040A1 (fr) | Nucleosides substitues en 4' | |
| AU2002218167A1 (en) | N-phenyl-2-pyrimidine-amine derivatives | |
| WO2004060882A8 (en) | Cb 1/cb 2 receptor ligands and their use in the treatment of pain | |
| TR200200579T2 (tr) | Amino-tirazolpiridin türevleri. | |
| MY137039A (en) | Thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof | |
| TR199802060T2 (tr) | Aminoisokinolinler ve aminopiridin türevlerinin iltihap önleyiciler olarak kullanimi. | |
| SE9900961D0 (sv) | Novel compounds | |
| BG103947A (en) | Derivatives of 9-oxymerythromycin | |
| SE9802208D0 (sv) | Novel compounds | |
| MY133107A (en) | Use of pyrimidine derivatives for the prophylaxis and therapy of cerebral ischemia | |
| TW200504029A (en) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| GEP20053617B (en) | Bridged Piperazine Derivatives | |
| UA83832C2 (ru) | Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и их применение | |
| GEP20074058B (en) | 4-(7-halo-2-quino(xa) linyloxy-phenoxy-propionic acid derivatives as antineoplastic agents | |
| DE69530988D1 (de) | Benzimidazolderivate mit dopaminerger wirkung | |
| SE0302570D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| MXPA02004441A (es) | Derivados de isoxazol como inhibidores de la fosfodiesterasa. | |
| SE0302572D0 (sv) | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof | |
| SE9802209D0 (sv) | Novel compounds | |
| ATE299027T1 (de) | Verwendung von übersulfatierten polysacchariden als hiv-hemmer | |
| TR200102009T2 (tr) | Serebral işlemi profilaksı ve tedavisi için formül I'e göre bileşiklerin kullanımı | |
| NO20042729L (no) | Heksasykliske forbindelser | |
| PT1232173E (pt) | Derivados do acido fusidico |