TR200200467T2 - Hidrodinamik dengelemeli oral yoldan ilaç verme sistemi. - Google Patents
Hidrodinamik dengelemeli oral yoldan ilaç verme sistemi.Info
- Publication number
- TR200200467T2 TR200200467T2 TR2002/00467T TR200200467T TR200200467T2 TR 200200467 T2 TR200200467 T2 TR 200200467T2 TR 2002/00467 T TR2002/00467 T TR 2002/00467T TR 200200467 T TR200200467 T TR 200200467T TR 200200467 T2 TR200200467 T2 TR 200200467T2
- Authority
- TR
- Turkey
- Prior art keywords
- delivery system
- drug delivery
- oral drug
- stomach
- hydrodynamic balancing
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title 1
- 229940126701 oral medication Drugs 0.000 title 1
- 210000002784 stomach Anatomy 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229940088679 drug related substance Drugs 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000000813 small intestine Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Mevcut bulus, en az bir ilaç maddesi, seker(ler), gaz olusturma bilesenleri ve istege bagli olarak farmasötik açidan kabul edilebilir yardimci bilesenlerden olusan oldukça gözenekli bir matris içeren, midede tutulan oral ilaç verme sistemi ile ilgilidir. Topaklar (çok partikülatli veya tek üniteli dozaj formu), taneler, granüller veya kapsüller formundaki farmasötik kompozisyon midede tutulurken ilaç(lar) uzun bir süre zarfinda ince bagirsagin üst kisimlarinda ve mide seviyelerinde seçici olarak birakilir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB1999/001386 WO2001010405A1 (en) | 1999-08-04 | 1999-08-04 | Hydrodynamically balanced oral drug delivery system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200200467T2 true TR200200467T2 (tr) | 2002-08-21 |
Family
ID=11004886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/00467T TR200200467T2 (tr) | 1999-08-04 | 2000-08-01 | Hidrodinamik dengelemeli oral yoldan ilaç verme sistemi. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1206249A4 (tr) |
| JP (1) | JP2003506400A (tr) |
| CN (1) | CN1376059A (tr) |
| AP (1) | AP2002002410A0 (tr) |
| AU (2) | AU5060499A (tr) |
| BR (1) | BR0012981A (tr) |
| CA (1) | CA2378468A1 (tr) |
| CZ (1) | CZ2002415A3 (tr) |
| EA (1) | EA200200126A1 (tr) |
| HK (1) | HK1047226A1 (tr) |
| HR (1) | HRP20020108A2 (tr) |
| HU (1) | HUP0202497A3 (tr) |
| IL (1) | IL147966A0 (tr) |
| MX (1) | MXPA02001272A (tr) |
| NZ (1) | NZ516959A (tr) |
| OA (1) | OA12003A (tr) |
| PL (1) | PL353321A1 (tr) |
| SK (1) | SK1832002A3 (tr) |
| TR (1) | TR200200467T2 (tr) |
| WO (2) | WO2001010405A1 (tr) |
| ZA (1) | ZA200200926B (tr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100457458B1 (ko) * | 2001-04-02 | 2004-11-17 | 삼아약품 주식회사 | 속용정 및 그의 제조방법 |
| RU2325152C2 (ru) | 2001-07-04 | 2008-05-27 | Сан Фармасьютикл Индастриз Лимитид | Удерживаемая в желудке система регулируемой доставки лекарственного средства |
| WO2003037296A2 (en) * | 2001-10-29 | 2003-05-08 | Labopharm Inc. | Methods and dosage forms for improving the bioavailability of therapeutic agents |
| US20050226926A1 (en) | 2002-07-25 | 2005-10-13 | Pfizer Inc | Sustained-release tablet composition of pramipexole |
| WO2005020879A2 (en) * | 2003-08-27 | 2005-03-10 | Vecta Ltd. | Compositions for treating pathologies that necessitate suppression of gastric acid secretion |
| TW200533391A (en) | 2004-03-25 | 2005-10-16 | Sun Pharmaceutical Ind Ltd | Gastric retention drug delivery system |
| CA2569919A1 (en) * | 2004-06-28 | 2006-01-05 | Solvay Pharmaceuticals B.V. | Oral sustained release formulation of tedisamil with gastric retention properties |
| UA93608C2 (ru) | 2004-08-13 | 2011-02-25 | Берингер Ингельхайм Интернациональ Гмбх | композициЯ таблетки пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, СПОСОБ EE ИЗГОТОВЛЕНИЯ И EE ПРИМЕНЕНИЕ |
| DE102004042139B4 (de) * | 2004-08-31 | 2009-06-10 | Aristocon Verwaltungs- Gmbh | Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit |
| EP1690540A1 (en) * | 2005-02-15 | 2006-08-16 | Neuro3D | Composition comprising ocaperidone |
| BRPI0620268B8 (pt) | 2005-12-22 | 2021-05-25 | Oakwood Laboratories LLC | composição eficaz como sistema de fornecimento para liberação controlada, seu uso, seu método de fabricação, e método para proteger um agente biologicamente ativo |
| EP1886665A1 (en) * | 2006-08-01 | 2008-02-13 | Boehringer Ingelheim Pharma GmbH & Co. KG | Gastro retentive delivery system |
| ATE476176T1 (de) * | 2007-03-02 | 2010-08-15 | Farnam Co Inc | Wachsähnliches material enthaltende tabletten mit verzögerter freisetzung |
| CN102202656A (zh) | 2008-08-15 | 2011-09-28 | 蒂宝制药公司 | 治疗和预防cns障碍的胃滞留药用组合物 |
| JP2012500230A (ja) | 2008-08-18 | 2012-01-05 | 北京天衡▲薬▼物研究院 | 胃内滞留薬物放出システム及びその製造方法と使用 |
| WO2010041279A2 (en) * | 2008-10-08 | 2010-04-15 | V.B. Medicare Pvt. Ltd. | Sustained release drug delivery system |
| EP2283824B1 (en) | 2009-07-30 | 2017-04-19 | Special Products Line S.p.A. | Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin |
| JP2013103879A (ja) * | 2011-11-10 | 2013-05-30 | Nakanihon Capsule Co Ltd | ハードカプセル |
| KR102241487B1 (ko) | 2013-02-20 | 2021-04-16 | 주식회사 종근당 | 제어방출 펠릿으로 된 약제학적 조성물 |
| JP6466399B2 (ja) * | 2013-03-15 | 2019-02-06 | アプレシア・ファーマスーティカルズ・カンパニー | トピラマートの急速分散性の剤形 |
| CN103462917A (zh) * | 2013-09-12 | 2013-12-25 | 南京正宽医药科技有限公司 | 一种用于抗病毒的阿昔洛韦片剂及其制备方法 |
| EP3468382A4 (en) * | 2016-06-14 | 2020-01-22 | Prevtec Microbia Inc | ANIMAL FEED PELLETS WITH FEED ADDITIVE, METHOD FOR THE PRODUCTION AND USE THEREOF |
| US10987311B2 (en) | 2017-06-16 | 2021-04-27 | Kashiv Specialty Pharmaceuticals, Llc | Extended release compositions comprising pyridostigmine |
| US10918597B2 (en) | 2017-06-16 | 2021-02-16 | Kashiv Specialty Pharmaceuticals, Llc | Gastroretentive dosage forms for sustained drug delivery |
| US10588863B2 (en) | 2017-06-16 | 2020-03-17 | Kashiv Biosciences, Llc | Extended release compositions comprising pyridostigmine |
| CN107375287B (zh) * | 2017-08-22 | 2019-11-29 | 安徽省肿瘤医院 | 一种硫酸阿托品在制备治疗原发性肝癌药物中的用途 |
| CN107441115A (zh) * | 2017-08-22 | 2017-12-08 | 安徽省肿瘤医院 | 一种维拉帕米联合碳酸氢钠在制备原发性肝癌治疗药物中的用途 |
| CN107349195A (zh) * | 2017-08-22 | 2017-11-17 | 安徽省肿瘤医院 | 一种维拉帕米在制备治疗转移性肝癌药物中的用途 |
| EP3824881B1 (en) | 2018-06-18 | 2022-02-16 | Amneal Complex Products Research LLC | Extended release compositions comprising pyridostigmine |
| EP3970701B1 (en) | 2018-06-27 | 2025-05-07 | Amneal Complex Products Research LLC | Self-regulating osmotic gastroretentive drug delivery systems |
| US11389398B2 (en) | 2019-05-14 | 2022-07-19 | Clexio Biosciences Ltd. | Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
| WO2022195476A1 (en) | 2021-03-15 | 2022-09-22 | Clexio Biosciences Ltd. | Gastroretentive devices for assessment of intragastric conditions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH675537A5 (tr) * | 1988-03-25 | 1990-10-15 | Ciba Geigy Ag | |
| US5096714A (en) * | 1988-06-28 | 1992-03-17 | Hauser-Kuhrts, Inc. | Prolonged release drug tablet formulations |
| EP0497977B1 (en) * | 1989-10-26 | 1995-03-15 | Nippon Shinyaku Company, Limited | Gastric preparation |
| MX9300110A (es) * | 1992-01-13 | 1994-07-29 | Gerhard Gergely | Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion. |
| GB9322314D0 (en) * | 1993-10-29 | 1993-12-15 | Scherer Ltd R P | Foam generating capsules |
| DE4403943A1 (de) * | 1994-02-08 | 1995-08-10 | Hexal Pharma Gmbh | Orale Azrneimittelzubereitung mit Diclofenac-Natrium |
| GB9418530D0 (en) * | 1994-09-14 | 1994-11-02 | Glaxo Group Ltd | Medicaments |
| US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| IT1293764B1 (it) * | 1997-07-23 | 1999-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua |
-
1999
- 1999-08-04 AP APAP/P/2002/002410A patent/AP2002002410A0/en unknown
- 1999-08-04 WO PCT/IB1999/001386 patent/WO2001010405A1/en not_active Ceased
- 1999-08-04 AU AU50604/99A patent/AU5060499A/en not_active Abandoned
-
2000
- 2000-08-01 PL PL00353321A patent/PL353321A1/xx not_active Application Discontinuation
- 2000-08-01 CN CN00813344A patent/CN1376059A/zh active Pending
- 2000-08-01 CZ CZ2002415A patent/CZ2002415A3/cs unknown
- 2000-08-01 CA CA002378468A patent/CA2378468A1/en not_active Abandoned
- 2000-08-01 EP EP00949840A patent/EP1206249A4/en not_active Withdrawn
- 2000-08-01 JP JP2001514939A patent/JP2003506400A/ja active Pending
- 2000-08-01 MX MXPA02001272A patent/MXPA02001272A/es not_active Application Discontinuation
- 2000-08-01 HK HK02108477.3A patent/HK1047226A1/zh unknown
- 2000-08-01 EA EA200200126A patent/EA200200126A1/ru unknown
- 2000-08-01 BR BR0012981-0A patent/BR0012981A/pt not_active IP Right Cessation
- 2000-08-01 WO PCT/IB2000/001083 patent/WO2001010419A1/en not_active Ceased
- 2000-08-01 IL IL14796600A patent/IL147966A0/xx unknown
- 2000-08-01 OA OA1200200041A patent/OA12003A/en unknown
- 2000-08-01 NZ NZ516959A patent/NZ516959A/en unknown
- 2000-08-01 HU HU0202497A patent/HUP0202497A3/hu unknown
- 2000-08-01 AU AU63099/00A patent/AU774957B2/en not_active Ceased
- 2000-08-01 TR TR2002/00467T patent/TR200200467T2/tr unknown
- 2000-08-01 HR HR20020108A patent/HRP20020108A2/xx not_active Application Discontinuation
- 2000-08-01 SK SK183-2002A patent/SK1832002A3/sk unknown
-
2002
- 2002-02-01 ZA ZA200200926A patent/ZA200200926B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6309900A (en) | 2001-03-05 |
| OA12003A (en) | 2006-04-18 |
| WO2001010405A1 (en) | 2001-02-15 |
| HUP0202497A2 (hu) | 2002-11-28 |
| HUP0202497A3 (en) | 2004-05-28 |
| CN1376059A (zh) | 2002-10-23 |
| EP1206249A4 (en) | 2004-12-22 |
| AP2002002410A0 (en) | 2002-03-31 |
| PL353321A1 (en) | 2003-11-17 |
| CA2378468A1 (en) | 2001-02-15 |
| IL147966A0 (en) | 2002-09-12 |
| HK1047226A1 (zh) | 2003-02-14 |
| ZA200200926B (en) | 2002-11-27 |
| EA200200126A1 (ru) | 2002-10-31 |
| SK1832002A3 (en) | 2002-08-06 |
| MXPA02001272A (es) | 2002-07-22 |
| CZ2002415A3 (cs) | 2002-08-14 |
| WO2001010419A1 (en) | 2001-02-15 |
| HRP20020108A2 (en) | 2003-12-31 |
| BR0012981A (pt) | 2002-06-18 |
| AU774957B2 (en) | 2004-07-15 |
| NZ516959A (en) | 2003-10-31 |
| JP2003506400A (ja) | 2003-02-18 |
| EP1206249A1 (en) | 2002-05-22 |
| AU5060499A (en) | 2001-03-05 |
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