TR200200521T2 - Parenteral cisplatin emülsiyonu. - Google Patents
Parenteral cisplatin emülsiyonu.Info
- Publication number
- TR200200521T2 TR200200521T2 TR2002/00521T TR200200521T TR200200521T2 TR 200200521 T2 TR200200521 T2 TR 200200521T2 TR 2002/00521 T TR2002/00521 T TR 2002/00521T TR 200200521 T TR200200521 T TR 200200521T TR 200200521 T2 TR200200521 T2 TR 200200521T2
- Authority
- TR
- Turkey
- Prior art keywords
- cisplatin
- mixtures
- emulsion
- oil
- aqueous
- Prior art date
Links
- DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 title abstract 4
- 229960004316 cisplatin Drugs 0.000 title abstract 4
- 239000000839 emulsion Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- 229940009662 edetate Drugs 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Parenteral ilaç verilmesinde düsük toksisiteye sahip sulu-yagli emülsiyon seklinde steril bir farmasötik cisplatin karisimlari tarif edilmistir. Esasen bu karisimlarin yagli fazinda cisplatinli yagli-sulu emülsiyon bulunmaktadir. Bu sinergitik karisimlarin üretim islemi tarif edilmistir. Cisplatin yagli fazda serpistirilir ve emülsiyon yapici kullanilarak sulu fazla emülsiyon yapilir. Bu karisimda belirtilen edetat, otoklavlamada ürünün renk degistirmesini önlemek ve stabilize etmek için gereken miktardadir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN535BO1999 IN186588B (tr) | 1999-07-28 | 1999-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200200521T2 true TR200200521T2 (tr) | 2002-07-22 |
Family
ID=11080186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/00521T TR200200521T2 (tr) | 1999-07-28 | 2000-07-26 | Parenteral cisplatin emülsiyonu. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6572884B1 (tr) |
| EP (1) | EP1204417B1 (tr) |
| JP (1) | JP2003505424A (tr) |
| KR (1) | KR20020063839A (tr) |
| CN (1) | CN100384436C (tr) |
| AP (1) | AP2002002384A0 (tr) |
| AT (1) | ATE269094T1 (tr) |
| AU (1) | AU778852B2 (tr) |
| BG (1) | BG106446A (tr) |
| BR (1) | BR0012796A (tr) |
| CA (1) | CA2379815A1 (tr) |
| CZ (1) | CZ2002268A3 (tr) |
| DE (1) | DE60011625T2 (tr) |
| EA (1) | EA004587B1 (tr) |
| ES (1) | ES2223571T3 (tr) |
| GE (1) | GEP20033046B (tr) |
| HU (1) | HUP0202269A3 (tr) |
| IL (1) | IL147786A0 (tr) |
| IN (1) | IN186588B (tr) |
| MX (1) | MXPA02002174A (tr) |
| NO (1) | NO20020394L (tr) |
| NZ (1) | NZ517502A (tr) |
| PL (1) | PL352577A1 (tr) |
| TR (1) | TR200200521T2 (tr) |
| WO (1) | WO2001007058A2 (tr) |
| YU (1) | YU13302A (tr) |
| ZA (1) | ZA200201548B (tr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003057129A1 (en) * | 2001-12-28 | 2003-07-17 | Terumo Kabushiki Kaisha | Blood bag system and method of inactivating pathogenic microorganisms |
| EP1799266A2 (en) * | 2004-09-13 | 2007-06-27 | Bharat Serums & Vaccines Ltd. | Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy |
| MX2008008009A (es) * | 2005-12-23 | 2008-09-12 | Ajay Gupta | Composicion de nutricion parenteral que contiene hierro. |
| US20100048607A1 (en) * | 2008-08-25 | 2010-02-25 | Chandrashekhar Kocherlakota | Formulations comprising palonosetron |
| CN102525921B (zh) * | 2012-02-06 | 2013-08-07 | 西安力邦制药有限公司 | 2,2’,6,6’-四异丙基-4,4’-二联苯酚脂微球制剂及其制备方法 |
| US9164954B2 (en) * | 2012-10-08 | 2015-10-20 | The Coca-Cola Company | Vending accommodation and accessibility |
| CN104490776B (zh) * | 2014-12-26 | 2017-06-16 | 本溪恒康制药有限公司 | 前列地尔注射液及其制备方法 |
| CN104490777B (zh) * | 2014-12-26 | 2019-07-23 | 北京蓝丹医药科技有限公司 | 一种丁酸氯维地平脂肪乳及其制备方法 |
| CN110870873A (zh) * | 2019-12-18 | 2020-03-10 | 吴昱晔 | 一种glut12蛋白抑制剂及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0647559B2 (ja) * | 1990-04-04 | 1994-06-22 | ナシヨナル・サイエンス・カウンシル | 改良された安定性と徐放作用を有する標的化学療法用抗癌剤エマルジョン及びその製法 |
| US5693337A (en) * | 1994-07-13 | 1997-12-02 | Wakamoto Pharmaceutical Co., Ltd. | Stable lipid emulsion |
| US6077545A (en) * | 1995-10-30 | 2000-06-20 | Matrix Pharmaceuticals, Inc. | Process and composition for therapeutic cisplatin (CDDP) |
-
1999
- 1999-07-28 IN IN535BO1999 patent/IN186588B/en unknown
-
2000
- 2000-07-26 YU YU13302A patent/YU13302A/sh unknown
- 2000-07-26 PL PL00352577A patent/PL352577A1/xx unknown
- 2000-07-26 BR BR0012796-5A patent/BR0012796A/pt not_active IP Right Cessation
- 2000-07-26 KR KR1020027001203A patent/KR20020063839A/ko not_active Ceased
- 2000-07-26 GE GEAP20006345A patent/GEP20033046B/en unknown
- 2000-07-26 IL IL14778600A patent/IL147786A0/xx unknown
- 2000-07-26 DE DE60011625T patent/DE60011625T2/de not_active Expired - Fee Related
- 2000-07-26 WO PCT/IN2000/000069 patent/WO2001007058A2/en not_active Ceased
- 2000-07-26 TR TR2002/00521T patent/TR200200521T2/tr unknown
- 2000-07-26 CZ CZ2002268A patent/CZ2002268A3/cs unknown
- 2000-07-26 AT AT00956778T patent/ATE269094T1/de not_active IP Right Cessation
- 2000-07-26 CN CNB008135487A patent/CN100384436C/zh not_active Expired - Fee Related
- 2000-07-26 US US10/048,151 patent/US6572884B1/en not_active Expired - Lifetime
- 2000-07-26 HU HU0202269A patent/HUP0202269A3/hu unknown
- 2000-07-26 EP EP00956778A patent/EP1204417B1/en not_active Expired - Lifetime
- 2000-07-26 CA CA002379815A patent/CA2379815A1/en not_active Abandoned
- 2000-07-26 ES ES00956778T patent/ES2223571T3/es not_active Expired - Lifetime
- 2000-07-26 EA EA200200217A patent/EA004587B1/ru not_active IP Right Cessation
- 2000-07-26 AP APAP/P/2002/002384A patent/AP2002002384A0/en unknown
- 2000-07-26 JP JP2001511942A patent/JP2003505424A/ja active Pending
- 2000-07-26 NZ NZ517502A patent/NZ517502A/en unknown
- 2000-07-26 MX MXPA02002174A patent/MXPA02002174A/es not_active Application Discontinuation
- 2000-07-26 AU AU68639/00A patent/AU778852B2/en not_active Ceased
-
2002
- 2002-01-25 NO NO20020394A patent/NO20020394L/no not_active Application Discontinuation
- 2002-02-25 ZA ZA200201548A patent/ZA200201548B/xx unknown
- 2002-02-26 BG BG06446A patent/BG106446A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA200200217A1 (ru) | 2002-08-29 |
| BG106446A (bg) | 2002-09-30 |
| ATE269094T1 (de) | 2004-07-15 |
| BR0012796A (pt) | 2002-04-30 |
| EA004587B1 (ru) | 2004-06-24 |
| WO2001007058A3 (en) | 2001-07-26 |
| GEP20033046B (en) | 2003-08-25 |
| CN1630524A (zh) | 2005-06-22 |
| US6572884B1 (en) | 2003-06-03 |
| NO20020394L (no) | 2002-02-28 |
| YU13302A (sh) | 2005-03-15 |
| DE60011625D1 (de) | 2004-07-22 |
| HUP0202269A3 (en) | 2004-11-29 |
| IL147786A0 (en) | 2002-08-14 |
| CZ2002268A3 (cs) | 2002-07-17 |
| AU778852B2 (en) | 2004-12-23 |
| EP1204417B1 (en) | 2004-06-16 |
| IN186588B (tr) | 2001-10-06 |
| DE60011625T2 (de) | 2005-07-07 |
| EP1204417A2 (en) | 2002-05-15 |
| CA2379815A1 (en) | 2001-02-01 |
| ZA200201548B (en) | 2004-01-28 |
| NZ517502A (en) | 2003-07-25 |
| ES2223571T3 (es) | 2005-03-01 |
| HUP0202269A2 (en) | 2002-10-28 |
| PL352577A1 (en) | 2003-08-25 |
| JP2003505424A (ja) | 2003-02-12 |
| MXPA02002174A (es) | 2005-04-11 |
| AP2002002384A0 (en) | 2002-03-31 |
| NO20020394D0 (no) | 2002-01-25 |
| CN100384436C (zh) | 2008-04-30 |
| KR20020063839A (ko) | 2002-08-05 |
| AU6863900A (en) | 2001-02-13 |
| WO2001007058A2 (en) | 2001-02-01 |
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