TR200200706T2 - Nöropatik ağrı tedavisi için retigabin kullanımı. - Google Patents

Nöropatik ağrı tedavisi için retigabin kullanımı.

Info

Publication number
TR200200706T2
TR200200706T2 TR2002/00706T TR200200706T TR200200706T2 TR 200200706 T2 TR200200706 T2 TR 200200706T2 TR 2002/00706 T TR2002/00706 T TR 2002/00706T TR 200200706 T TR200200706 T TR 200200706T TR 200200706 T2 TR200200706 T2 TR 200200706T2
Authority
TR
Turkey
Prior art keywords
retigabine
neuropathic pain
treatment
ethoxycarbonylaminobenzene
fluorobenzylamino
Prior art date
Application number
TR2002/00706T
Other languages
English (en)
Inventor
Rundfeldt Chris
Bartsch Reni
Rostock Angelika
Tober Christine
Dost Rita
Original Assignee
Viatris Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh & Co. Kg filed Critical Viatris Gmbh & Co. Kg
Publication of TR200200706T2 publication Critical patent/TR200200706T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Mevcut bulus; nöropatik agri tedavisi veya profilaksisine yönelik 1 formülündeki 2-amino-4(4-flüorobenzilamino)-1-etoksikarbonilaminobenzen (INN: retigabin) veya buna ait farmasötik yönden faydali tuzlar ile ilgilidir.
TR2002/00706T 1999-09-27 2000-09-22 Nöropatik ağrı tedavisi için retigabin kullanımı. TR200200706T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/406,135 US6117900A (en) 1999-09-27 1999-09-27 Use of retigabine for the treatment of neuropathic pain

Publications (1)

Publication Number Publication Date
TR200200706T2 true TR200200706T2 (tr) 2002-10-21

Family

ID=23606675

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00706T TR200200706T2 (tr) 1999-09-27 2000-09-22 Nöropatik ağrı tedavisi için retigabin kullanımı.

Country Status (35)

Country Link
US (1) US6117900A (tr)
EP (1) EP1223927B1 (tr)
JP (1) JP2003510273A (tr)
KR (1) KR100730829B1 (tr)
CN (2) CN101444498A (tr)
AR (1) AR026163A1 (tr)
AT (1) ATE288748T1 (tr)
AU (1) AU777764B2 (tr)
BG (1) BG65795B1 (tr)
BR (1) BR0014293A (tr)
CA (2) CA2659048A1 (tr)
CZ (1) CZ295980B6 (tr)
DE (1) DE50009504D1 (tr)
DK (1) DK1223927T3 (tr)
EE (1) EE05073B1 (tr)
ES (1) ES2237461T3 (tr)
HK (1) HK1052471A1 (tr)
HR (1) HRP20020234A2 (tr)
HU (1) HUP0202853A3 (tr)
IL (3) IL148309A0 (tr)
IS (1) IS6303A (tr)
MX (1) MXPA02003179A (tr)
NO (1) NO329744B1 (tr)
NZ (1) NZ517616A (tr)
PL (1) PL200847B1 (tr)
PT (1) PT1223927E (tr)
RS (1) RS50091B (tr)
RU (1) RU2264813C2 (tr)
SI (1) SI1223927T1 (tr)
SK (1) SK286057B6 (tr)
TR (1) TR200200706T2 (tr)
TW (1) TWI257304B (tr)
UA (1) UA72550C2 (tr)
WO (1) WO2001022953A2 (tr)
ZA (1) ZA200202449B (tr)

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JP2006503025A (ja) * 2002-09-05 2006-01-26 サイオス インク． ｐ３８ＭＡＰキナーゼの抑制による疼痛治療
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WO2004054511A2 (en) * 2002-12-13 2004-07-01 The Regents Of The University Of California Analgesic combination comprising nalbuphine
MXPA05006463A (es) * 2002-12-27 2005-08-26 Lundbeck & Co As H Derivados de 1,2,4-triaminobenceno, utiles para tratar transtornos del sistema nervioso central.
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EP1631546A1 (en) * 2003-04-25 2006-03-08 H. Lundbeck A/S Sustituted indoline and indole derivatives
US20050089559A1 (en) * 2003-10-23 2005-04-28 Istvan Szelenyi Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
TWI357901B (en) 2004-03-12 2012-02-11 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivati
EP1861394A1 (en) 2005-03-03 2007-12-05 H.Lundbeck A/S Substituted pyridine derivatives
US7960436B2 (en) * 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
US20080045534A1 (en) * 2006-08-18 2008-02-21 Valeant Pharmaceuticals North America Derivatives of 1,3-diamino benzene as potassium channel modulators
BRPI0716715B1 (pt) * 2006-08-23 2021-07-06 Xenon Pharmaceuticals, Inc Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potássio, seus usos, produto, composição, comprimido e cápsula
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
CA2670966A1 (en) * 2006-11-28 2008-06-05 Valeant Pharmaceuticals International 1,4 diamino bicyclic retigabine analogues as potassium channel modulators
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
US8765815B2 (en) 2007-09-20 2014-07-01 Ramot At Tel-Aviv University Ltd. N-phenyl anthranilic acid derivatives and uses thereof
US20100120906A1 (en) * 2008-07-18 2010-05-13 Valeant Pharmaceuticals International Modified release formulation and methods of use
US20100323015A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
US20100323016A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
DE102009013613A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Trockenverarbeitung von Retigabin
DE102009013611A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Festes Retigabin in nicht-kristalliner Form
DE102009013612A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Retigabin-Tabletten, bevorzugt mit modifizierter Freisetzung
IT1398282B1 (it) * 2009-07-30 2013-02-22 Difass S A Ora Farmapros S P A Composizione comprendente acido alfa-lipoico e carnosina per il trattamento della sindrome dell arto fantasma
US20110087650A1 (en) * 2009-10-06 2011-04-14 Johnson Controls Technology Company Creation and use of causal relationship models in building management systems and applications
TR201002473A2 (tr) * 2010-03-31 2011-09-21 Mustafa Nevzat �La� Sanay�� A.�. Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi.
RU2446795C1 (ru) * 2011-03-31 2012-04-10 Федеральное государственное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения и социального развития Российской Федерации" ФГУ "МНИОИ им. П.А. Герцена "Минздравсоцразвития России" Способ предотвращения фантомного болевого синдрома после ампутации конечностей
CN102531966B (zh) * 2011-12-23 2013-07-24 山东创新药物研发有限公司 瑞替加滨的晶型d及其制备方法
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
US9345689B2 (en) * 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
CN103271899A (zh) * 2012-12-30 2013-09-04 北京阜康仁生物制药科技有限公司 瑞替加滨粉碎粒度在制剂中的应用
CN105919990A (zh) * 2016-06-29 2016-09-07 青岛云天生物技术有限公司 用于预防和治疗神经病理性疼痛的药物组合物及其用途
CN106176715A (zh) * 2016-06-29 2016-12-07 青岛云天生物技术有限公司 一种神经病理性疼痛治疗用药物组合物及其用途
WO2019014547A1 (en) 2017-07-14 2019-01-17 Texas Tech University System FUNCTIONALIZED PYRIDINE CARBAMATES HAVING ENHANCED NEUROPROTECTOR ACTIVITY
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TWI886158B (zh) 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
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Also Published As

Publication number Publication date
DK1223927T3 (da) 2005-04-11
CZ295980B6 (cs) 2005-12-14
ATE288748T1 (de) 2005-02-15
MXPA02003179A (es) 2003-08-20
EP1223927B1 (de) 2005-02-09
RU2002109240A (ru) 2004-01-10
NZ517616A (en) 2002-12-20
TWI257304B (en) 2006-07-01
JP2003510273A (ja) 2003-03-18
HUP0202853A3 (en) 2003-10-28
YU20302A (sh) 2005-03-15
NO20021418D0 (no) 2002-03-21
AU777764B2 (en) 2004-10-28
RU2264813C2 (ru) 2005-11-27
PT1223927E (pt) 2005-06-30
CZ2002989A3 (cs) 2002-08-14
IL187030A0 (en) 2008-02-09
KR100730829B1 (ko) 2007-06-20
UA72550C2 (en) 2005-03-15
CN1409632A (zh) 2003-04-09
EP1223927A2 (de) 2002-07-24
AU7906100A (en) 2001-04-30
EE05073B1 (et) 2008-10-15
HRP20020234A2 (en) 2003-06-30
IS6303A (is) 2002-03-18
HUP0202853A2 (hu) 2002-12-28
ES2237461T3 (es) 2005-08-01
WO2001022953A2 (de) 2001-04-05
RS50091B (sr) 2009-01-22
BG106450A (en) 2002-09-30
PL353393A1 (en) 2003-11-17
BR0014293A (pt) 2002-05-21
SI1223927T1 (tr) 2005-08-31
WO2001022953A3 (de) 2002-05-23
PL200847B1 (pl) 2009-02-27
HK1052471A1 (zh) 2003-09-19
SK2922002A3 (en) 2002-08-06
CA2384504A1 (en) 2001-04-05
IL187030A (en) 2011-06-30
NO20021418L (no) 2002-03-21
CN101444498A (zh) 2009-06-03
BG65795B1 (bg) 2009-12-31
EE200200145A (et) 2003-04-15
CA2384504C (en) 2009-05-26
SK286057B6 (sk) 2008-02-05
DE50009504D1 (de) 2005-03-17
CN100522155C (zh) 2009-08-05
US6117900A (en) 2000-09-12
CA2659048A1 (en) 2001-04-05
KR20020042691A (ko) 2002-06-05
IL148309A0 (en) 2002-09-12
IL148309A (en) 2007-12-03
AR026163A1 (es) 2003-01-29
NO329744B1 (no) 2010-12-13
ZA200202449B (en) 2003-03-26

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