TR200200930T2 - Katyonik dosper virosomlar - Google Patents

Katyonik dosper virosomlar

Info

Publication number
TR200200930T2
TR200200930T2 TR2002/00930T TR200200930T TR200200930T2 TR 200200930 T2 TR200200930 T2 TR 200200930T2 TR 2002/00930 T TR2002/00930 T TR 2002/00930T TR 200200930 T TR200200930 T TR 200200930T TR 200200930 T2 TR200200930 T2 TR 200200930T2
Authority
TR
Turkey
Prior art keywords
cationic
virosomes
relates
dosper
lipids
Prior art date
Application number
TR2002/00930T
Other languages
English (en)
Inventor
Rudolf Walti Ernst
Gl�Ck Reinhard
Klein Peter
Original Assignee
Nika Health Products Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/414,872 external-priority patent/US6210708B1/en
Application filed by Nika Health Products Limited filed Critical Nika Health Products Limited
Publication of TR200200930T2 publication Critical patent/TR200200930T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Bu bulus bir non-sendai viral hemaglutinin olan en az bir aktif füzojenik peptid ihtiva eden bir katyonik virozom ile ilgili olup, burada virozom membrani toplam lipidlere göre agirlik bazinda %5 ila %30 oraninda 1,3-dioleoiloksi-2(6-karboksi-spermil)-propilamidi (DOSPER) fosfatidilkolin (PC) veya bunu bir türevi ve opsiyonel olarakda fosfatidiletanolamin (PE) ve/veya sair katyonik lipidler ile kombinasyon halinde ihtiva eder. Virozomlar negatif sarjli maddelerin ve özellikle de nükleik asit bilesiklerinin, hedef hücrelere verilmesinde çok randimanli olur. Bu bulus, ayni zamanda,virozomlarin imaline yönelik bir metod ve bunlarin diyagnostik , kozmetik, tibbi veya bilimsel gayelerle kullanimlari ile ilgilidir.
TR2002/00930T 1999-10-08 2000-09-29 Katyonik dosper virosomlar TR200200930T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/414,872 US6210708B1 (en) 1996-05-08 1999-10-08 Cationic virosomes as transfer system for genetic material

Publications (1)

Publication Number Publication Date
TR200200930T2 true TR200200930T2 (tr) 2002-08-21

Family

ID=23643351

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00930T TR200200930T2 (tr) 1999-10-08 2000-09-29 Katyonik dosper virosomlar

Country Status (19)

Country Link
EP (1) EP1217990B1 (tr)
JP (1) JP2003512306A (tr)
KR (1) KR100869195B1 (tr)
AT (1) ATE258428T1 (tr)
AU (1) AU778399B2 (tr)
CA (1) CA2388053A1 (tr)
CO (1) CO5280052A1 (tr)
CZ (1) CZ20021216A3 (tr)
DE (1) DE60008006T2 (tr)
DK (1) DK1217990T3 (tr)
ES (1) ES2215073T3 (tr)
HU (1) HUP0202809A2 (tr)
NO (1) NO20021607L (tr)
PE (1) PE20010703A1 (tr)
PL (1) PL355231A1 (tr)
RU (1) RU2002112224A (tr)
SK (1) SK4782002A3 (tr)
TR (1) TR200200930T2 (tr)
WO (1) WO2001026628A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045582A1 (en) * 2002-11-21 2004-06-03 Pevion Biotech Ltd. High-efficiency fusogenic vesicles, methods of producing them, and pharmaceutical compositions containing them
JP4497894B2 (ja) * 2003-11-07 2010-07-07 明彦 河合 物質導入剤およびその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL296382A1 (en) * 1991-02-02 1993-11-02 Nika Health Products Ltd Li Li Artificial membrane beads containing functionally active peptides responsible for fusion as a drug administering system
DE19521412A1 (de) * 1995-06-14 1996-12-19 Boehringer Mannheim Gmbh Neue kationische und polykationische Amphiphile, diese enthaltende Reagenzien und deren Verwendung
CZ299809B6 (cs) * 1996-05-08 2008-12-03 Nika Health Products Limited Lipidový vácek mající kladne nabitou membránu z lipidové dvojvrstvy pro prenos genetického materiálu a zpusob jeho prípravy
DE69736692T2 (de) * 1996-07-16 2007-06-14 Archibald James Mixson Kationisches Vehikel: DNS Komplexe und ihre Verwendung in Gentherapie

Also Published As

Publication number Publication date
ATE258428T1 (de) 2004-02-15
ES2215073T3 (es) 2004-10-01
PE20010703A1 (es) 2001-07-11
AU778399B2 (en) 2004-12-02
CA2388053A1 (en) 2001-04-19
WO2001026628A1 (en) 2001-04-19
PL355231A1 (en) 2004-04-05
NO20021607D0 (no) 2002-04-05
RU2002112224A (ru) 2004-01-10
DE60008006D1 (de) 2004-03-04
NO20021607L (no) 2002-06-07
KR100869195B1 (ko) 2008-11-18
DK1217990T3 (da) 2004-05-24
CZ20021216A3 (cs) 2002-10-16
KR20020063872A (ko) 2002-08-05
CO5280052A1 (es) 2003-05-30
EP1217990A1 (en) 2002-07-03
EP1217990B1 (en) 2004-01-28
DE60008006T2 (de) 2004-09-09
HUP0202809A2 (hu) 2002-12-28
JP2003512306A (ja) 2003-04-02
SK4782002A3 (en) 2002-09-10
AU7785000A (en) 2001-04-23

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