TR200200972T2 - İkameli 2-fenilbenzimidazoller, üretimleri ve kullanımları - Google Patents

İkameli 2-fenilbenzimidazoller, üretimleri ve kullanımları

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Publication number
TR200200972T2
TR200200972T2 TR2002/00972T TR200200972T TR200200972T2 TR 200200972 T2 TR200200972 T2 TR 200200972T2 TR 2002/00972 T TR2002/00972 T TR 2002/00972T TR 200200972 T TR200200972 T TR 200200972T TR 200200972 T2 TR200200972 T2 TR 200200972T2
Authority
TR
Turkey
Prior art keywords
phenylbenzimidazoles
production
substituted
relates
structures
Prior art date
Application number
TR2002/00972T
Other languages
English (en)
Inventor
Lubisch Wilfried
Kock Micheal
H�Ger Thomas
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR200200972T2 publication Critical patent/TR200200972T2/tr

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    • C07—ORGANIC CHEMISTRY
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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
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Abstract

Bulus genel formül (I)'in ya da (II)'nin yeni 2-fenilbenzimidazolleri ile, ki burada bulunan radikaller açiklamada belirtilmis olan anlamlara sahiptirler, ve bunlarin tautomerik yapilari, mümkün olan enetiomerik ve diasteromerik yapilari ile, bunlarin ön ilaçlari ve fizyolojik olarak uygun olan olasi tuzlari ile ilgilidir. Bulus söz konusu bilesiklerin üretimi ve bunlarin kullanimlari ile de ilgilidir.
TR2002/00972T 1998-11-03 1999-10-28 İkameli 2-fenilbenzimidazoller, üretimleri ve kullanımları TR200200972T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19850709 1998-11-03
DE19852801 1998-11-16
DE19908733 1999-03-01

Publications (1)

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TR200200972T2 true TR200200972T2 (tr) 2002-07-22

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TR2001/01239T TR200101239T2 (tr) 1998-11-03 1999-10-28 İkameli-2-fenilbenzimidazoller, üretimleri ve kullanımları
TR2002/00972T TR200200972T2 (tr) 1998-11-03 1999-10-28 İkameli 2-fenilbenzimidazoller, üretimleri ve kullanımları

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TR2001/01239T TR200101239T2 (tr) 1998-11-03 1999-10-28 İkameli-2-fenilbenzimidazoller, üretimleri ve kullanımları

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US (1) US7781596B1 (tr)
EP (2) EP1127052B1 (tr)
JP (4) JP2002528531A (tr)
KR (1) KR20010100977A (tr)
CN (1) CN1331682A (tr)
AR (1) AR024517A1 (tr)
AT (1) ATE284392T1 (tr)
AU (1) AU765224B2 (tr)
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CY (1) CY1105410T1 (tr)
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DE (1) DE59911249D1 (tr)
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PL (1) PL347500A1 (tr)
PT (1) PT1127052E (tr)
SK (1) SK5952001A3 (tr)
TR (2) TR200101239T2 (tr)
WO (1) WO2000026192A1 (tr)

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US6919366B2 (en) 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6911462B2 (en) 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
TR200101239T2 (tr) 1998-11-03 2001-11-21 Basf Aktiengesellschaft İkameli-2-fenilbenzimidazoller, üretimleri ve kullanımları
DE19920936A1 (de) * 1999-05-07 2000-11-09 Basf Ag Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung
US6759425B2 (en) 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
BR0208010A (pt) 2001-03-12 2004-12-21 Avanir Pharmaceuticals Composto de benzimidazol para modulação de ige e inibição de proliferação celular
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