ATE258930T1 - Dihydrobenzifurane - Google Patents

Dihydrobenzifurane

Info

Publication number
ATE258930T1
ATE258930T1 AT98966288T AT98966288T ATE258930T1 AT E258930 T1 ATE258930 T1 AT E258930T1 AT 98966288 T AT98966288 T AT 98966288T AT 98966288 T AT98966288 T AT 98966288T AT E258930 T1 ATE258930 T1 AT E258930T1
Authority
AT
Austria
Prior art keywords
dihydrobenzifurans
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
AT98966288T
Other languages
English (en)
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-Ruediger Ulrich
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE258930T1 publication Critical patent/ATE258930T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98966288T 1997-12-15 1998-12-10 Dihydrobenzifurane ATE258930T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
ATE258930T1 true ATE258930T1 (de) 2004-02-15

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966288T ATE258930T1 (de) 1997-12-15 1998-12-10 Dihydrobenzifurane

Country Status (17)

Country Link
US (1) US6380196B1 (de)
EP (1) EP1042319B1 (de)
JP (1) JP2002508368A (de)
AT (1) ATE258930T1 (de)
AU (1) AU753576B2 (de)
CA (1) CA2314111A1 (de)
CZ (1) CZ299304B6 (de)
DE (1) DE69821530T2 (de)
DK (1) DK1042319T3 (de)
EE (1) EE04312B1 (de)
ES (1) ES2216349T3 (de)
HU (1) HU225114B1 (de)
IL (1) IL136359A (de)
PL (1) PL191236B1 (de)
PT (1) PT1042319E (de)
SI (1) SI1042319T1 (de)
WO (1) WO1999031090A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
AU7654200A (en) * 1999-09-14 2001-04-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
HUP0203487A2 (hu) 1999-10-25 2003-02-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahidrotiopirán-ftalazinon-származékok, mint PDE4-inhibitorok és ezeket tartalmazó gyógyszerkészítmények
WO2001030766A1 (en) * 1999-10-25 2001-05-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pde 4 inhibitors
NZ522882A (en) 2000-06-05 2004-07-30 Altana Pharma Bv Pyridazinone compounds effective as beta-2-adrenoreceptor agonists as well as PDE4-inhibitors
CZ20032491A3 (cs) * 2001-02-15 2004-01-14 Altana Pharma Ag Ftalazinonpiperidinové deriváty
EP1385848A2 (de) 2001-04-25 2004-02-04 ALTANA Pharma AG Phtalazinone derivate verwendbar als pde4/7 inhibitoren
BR0209076A (pt) * 2001-04-25 2004-08-10 Altana Pharma Ag Derivados de piperazino e seu uso como inibidor de pde4
CN1646118A (zh) * 2002-03-29 2005-07-27 中外制药株式会社 预防或治疗呼吸系统疾病的药物组合物
US20060166995A1 (en) * 2002-08-10 2006-07-27 Altana Pharma Ag Piperidine-n-oxide-derivatives
BR0313330A (pt) * 2002-08-10 2005-06-14 Altana Pharma Ag Piperidina-ftalazonas substituìdas com pirrolidinadiona como inibidores de pde4
EP1556369A1 (de) * 2002-08-10 2005-07-27 ALTANA Pharma AG Pyridazinonderivate als pde4-inhibitoren
WO2004018449A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
US20080227790A1 (en) * 2004-02-04 2008-09-18 Altana Pharma Ag Pyridazinone Derivatives and their Use as Pde4 Inhibitors
DE602005005638T2 (de) * 2004-02-04 2009-05-14 Nycomed Gmbh 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-on-derivate als pde4-inhibitoren
WO2006095666A1 (ja) * 2005-03-07 2006-09-14 Kyorin Pharmaceutical Co., Ltd. ピラゾロピリジン－４－イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするｐｄｅ阻害剤
AR057986A1 (es) * 2005-11-21 2008-01-09 Japan Tobacco Inc Compuesto heterociclico y su uso farmaceutico
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
DE59009351D1 (de) * 1989-04-17 1995-08-03 Byk Gulden Lomberg Chem Fab Neue arylpyridazine, ihre herstellung, verwendung und sie enthaltende arzneimittel.
JP3120857B2 (ja) 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
EP0553174B1 (de) * 1990-10-16 1998-07-08 Byk Gulden Lomberg Chemische Fabrik Gmbh Arylpyridazinone
WO1992019602A1 (de) * 1991-04-26 1992-11-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
EP0593567B1 (de) * 1991-07-05 1996-08-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung substituierter pyridazine gegen dermatosen
ZA927755B (en) * 1991-10-09 1994-04-08 Syntex Inc Pyrido pyridazinone and pyridazinthione compounds
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
NZ257955A (en) * 1992-12-02 1996-05-28 Pfizer Catechol diethers pharmaceutical compositions
US5411935A (en) * 1993-03-17 1995-05-02 Sumitomo Chemical Co., Ltd. Dihydrobenzofuran derivatives, their production and use
DK0772610T3 (da) * 1994-07-22 2001-01-29 Byk Gulden Lomberg Chem Fab Dihydrobenzofuraner
DE69533057T2 (de) 1994-08-09 2005-06-16 Eisai Co., Ltd. Kondensierte pyridazinverbindungen
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
SI1042319T1 (en) 2004-08-31
HU225114B1 (en) 2006-06-28
EE04312B1 (et) 2004-06-15
PL341239A1 (en) 2001-03-26
HUP0004561A2 (hu) 2002-03-28
PT1042319E (pt) 2004-06-30
EP1042319A1 (de) 2000-10-11
JP2002508368A (ja) 2002-03-19
US6380196B1 (en) 2002-04-30
DE69821530D1 (de) 2004-03-11
PL191236B1 (pl) 2006-04-28
HUP0004561A3 (en) 2002-04-29
DE69821530T2 (de) 2004-12-23
AU2270199A (en) 1999-07-05
AU753576B2 (en) 2002-10-24
CZ299304B6 (cs) 2008-06-11
DK1042319T3 (da) 2004-06-01
IL136359A (en) 2003-03-12
EE200000335A (et) 2001-10-15
IL136359A0 (en) 2001-06-14
EP1042319B1 (de) 2004-02-04
ES2216349T3 (es) 2004-10-16
CA2314111A1 (en) 1999-06-24
CZ20002218A3 (cs) 2000-11-15
WO1999031090A1 (en) 1999-06-24

Similar Documents

Publication Publication Date Title
DE69821530D1 (de) Dihydrobenzifurane
DK1070056T3 (da) Phthalazinon-PDE III/IV-inhibitorer
ATE269850T1 (de) 3-thiocarbamoylpyrazol-derivate als pestiziden
DE69910831D1 (de) Epothilonderivate und ihre verwendung als antitumormittel
DK1147089T3 (da) Phenylphenanthridiner med PDE-IV-inhiberende virkning
EE200000033A (et) Uudsed tetrasoolderivaadid
TR200000059T2 (tr) Piridin türevleri
TR199901653T2 (xx) Fitalazinonlar.
YU19499A (sh) Benzonaftiridini kao bronhijalni terapeutici
DE59909760D1 (de) Benzonaphthyridin-n-oxide mit pde3 und pde4 inhibierender aktivität
PT1086096E (pt) Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4
NO20022976D0 (no) 2-(1H-indol-3yl)-2-okso-acetamider med antitumoraktivitet
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
ATE294793T1 (de) Phenantrhridin-n-oxides mit pde-iv hemmender wirkung
DE60202669D1 (de) 6-phenylbenzonaphthyidine
ATE286887T1 (de) Antibakterielle mittel
ATE213236T1 (de) Substituierte benzyloxyimino-verbindungen
BR0110328A (pt) Compostos heterocìclicos com atividade antiinflamatória
DE59711147D1 (de) Neue Imidazo- und Oxazolopyridine als Phosphodiesterase Inhibitoren.
AU758194C (en) Novel benzimidazoles and benzoxazoles

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1042319

Country of ref document: EP

REN Ceased due to non-payment of the annual fee