ATE258930T1 - Dihydrobenzifurane - Google Patents

Dihydrobenzifurane

Info

Publication number
ATE258930T1
ATE258930T1 AT98966288T AT98966288T ATE258930T1 AT E258930 T1 ATE258930 T1 AT E258930T1 AT 98966288 T AT98966288 T AT 98966288T AT 98966288 T AT98966288 T AT 98966288T AT E258930 T1 ATE258930 T1 AT E258930T1
Authority
AT
Austria
Prior art keywords
dihydrobenzifurans
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
AT98966288T
Other languages
English (en)
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-Ruediger Ulrich
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE258930T1 publication Critical patent/ATE258930T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT98966288T 1997-12-15 1998-12-10 Dihydrobenzifurane ATE258930T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
ATE258930T1 true ATE258930T1 (de) 2004-02-15

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966288T ATE258930T1 (de) 1997-12-15 1998-12-10 Dihydrobenzifurane

Country Status (17)

Country Link
US (1) US6380196B1 (de)
EP (1) EP1042319B1 (de)
JP (1) JP2002508368A (de)
AT (1) ATE258930T1 (de)
AU (1) AU753576B2 (de)
CA (1) CA2314111A1 (de)
CZ (1) CZ299304B6 (de)
DE (1) DE69821530T2 (de)
DK (1) DK1042319T3 (de)
EE (1) EE04312B1 (de)
ES (1) ES2216349T3 (de)
HU (1) HU225114B1 (de)
IL (1) IL136359A (de)
PL (1) PL191236B1 (de)
PT (1) PT1042319E (de)
SI (1) SI1042319T1 (de)
WO (1) WO1999031090A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL200923B1 (pl) 1999-08-21 2009-02-27 Nycomed Gmbh Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
WO2001019818A1 (en) * 1999-09-14 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
ATE374189T1 (de) * 1999-10-25 2007-10-15 Nycomed Gmbh Phthalazinon-derivate als pde 4 hemmer
AU781137B2 (en) 1999-10-25 2005-05-05 Altana Pharma Ag Tetrahydrothiopy ranphthalazinone derivatives as PDE4 inhibitors
CN1471515A (zh) * 2000-06-05 2004-01-28 ��̹��ҽҩ��˾ 作为β2-肾上腺素受体激动剂及PDE-4抑制剂的有效的化合物
NZ527424A (en) * 2001-02-15 2005-02-25 Altana Pharma Ag Phthalayinone-piperidino-derivatives as PDE4 inhibitors
BR0209076A (pt) * 2001-04-25 2004-08-10 Altana Pharma Ag Derivados de piperazino e seu uso como inibidor de pde4
EP1385848A2 (de) 2001-04-25 2004-02-04 ALTANA Pharma AG Phtalazinone derivate verwendbar als pde4/7 inhibitoren
AU2003219559A1 (en) * 2002-03-29 2003-10-13 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for preventing or treating respiratory disease
HRP20050198A2 (hr) * 2002-08-10 2006-04-30 Altana Pharma Ag Piperidin-piridazoni i ftalazoni kao inhibitori pde4
WO2004018449A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
US20060166995A1 (en) * 2002-08-10 2006-07-27 Altana Pharma Ag Piperidine-n-oxide-derivatives
US20060167001A1 (en) * 2002-08-10 2006-07-27 Sterk Jan G Pyridazinone-derivatives as pde4 inhibitors
JP2006522151A (ja) 2003-04-01 2006-09-28 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ 不妊症におけるホスホジエステラーゼ阻害剤
EP1716133B1 (de) 2004-02-04 2008-03-26 Nycomed GmbH 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-on-derivate als pde4-inhibitoren
US20080227790A1 (en) * 2004-02-04 2008-09-18 Altana Pharma Ag Pyridazinone Derivatives and their Use as Pde4 Inhibitors
US7763617B2 (en) * 2005-03-07 2010-07-27 Kyorin Pharmaceutical Co., Ltd. Pyrazolopyridine-4-yl pyridazinone derivatives and addition salts thereof, and PDE inhibitors comprising the same derivatives or salts as active ingredient
AR057986A1 (es) * 2005-11-21 2008-01-09 Japan Tobacco Inc Compuesto heterociclico y su uso farmaceutico
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
AU640137B2 (en) * 1989-04-17 1993-08-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel arylpyridazines, their manufacture, use and medicaments containing them
JP3120857B2 (ja) 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
WO1992006963A1 (de) * 1990-10-16 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Arylpyridazinone
US5449676A (en) * 1991-04-26 1995-09-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyridazines
EP0523513A1 (de) * 1991-07-05 1993-01-20 Byk Gulden Lomberg Chemische Fabrik GmbH Verwendung substituierter Pyridazine zur Behandlung von Dermatosen
JP3245165B2 (ja) * 1991-10-09 2002-01-07 シンテックス（ユー・エス・エイ）・インコーポレイテッド ピリドピリダジノンおよびピリダジンチオン化合物
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
DK0672031T3 (da) 1992-12-02 2003-06-10 Pfizer Catecholdiethere som selektive PDE IV-inhibitorer
US5476834A (en) * 1993-03-17 1995-12-19 Sumitomo Chemical Company, Limited Dihydrobenzofuran derivatives, their production and use
ES2152414T3 (es) * 1994-07-22 2001-02-01 Byk Gulden Lomberg Chem Fab Dihidrobenzofuranos.
EP0722936B1 (de) 1994-08-09 2004-05-19 Eisai Co., Ltd. Kondensierte pyridazinverbindungen
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
PL191236B1 (pl) 2006-04-28
US6380196B1 (en) 2002-04-30
ES2216349T3 (es) 2004-10-16
HU225114B1 (en) 2006-06-28
IL136359A (en) 2003-03-12
WO1999031090A1 (en) 1999-06-24
DE69821530D1 (de) 2004-03-11
EP1042319A1 (de) 2000-10-11
EE04312B1 (et) 2004-06-15
AU2270199A (en) 1999-07-05
EE200000335A (et) 2001-10-15
AU753576B2 (en) 2002-10-24
CZ299304B6 (cs) 2008-06-11
DE69821530T2 (de) 2004-12-23
SI1042319T1 (en) 2004-08-31
IL136359A0 (en) 2001-06-14
CA2314111A1 (en) 1999-06-24
CZ20002218A3 (cs) 2000-11-15
HUP0004561A3 (en) 2002-04-29
HUP0004561A2 (hu) 2002-03-28
JP2002508368A (ja) 2002-03-19
EP1042319B1 (de) 2004-02-04
DK1042319T3 (da) 2004-06-01
PT1042319E (pt) 2004-06-30
PL341239A1 (en) 2001-03-26

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