TR200602095T2 - Hümanize Anti-LT-Beta-R antikorları - Google Patents

Hümanize Anti-LT-Beta-R antikorları

Info

Publication number
TR200602095T2
TR200602095T2 TR2006/02095T TR200602095T TR200602095T2 TR 200602095 T2 TR200602095 T2 TR 200602095T2 TR 2006/02095 T TR2006/02095 T TR 2006/02095T TR 200602095 T TR200602095 T TR 200602095T TR 200602095 T2 TR200602095 T2 TR 200602095T2
Authority
TR
Turkey
Prior art keywords
beta
antibodies
humanized anti
humanized
humanized antibodies
Prior art date
Application number
TR2006/02095T
Other languages
English (en)
Inventor
Gardber Ellen
W. Saldanha Jose
Lyne Paul
Original Assignee
Biogen Idec Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Ma Inc. filed Critical Biogen Idec Ma Inc.
Publication of TR200602095T2 publication Critical patent/TR200602095T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LT-Beta-R'ye insancıllaştırılmış antikorlar ve bunların kullanım metodu sağlanmıştır.
TR2006/02095T 2000-10-13 2001-10-12 Hümanize Anti-LT-Beta-R antikorları TR200602095T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24028500P 2000-10-13 2000-10-13
US27528901P 2001-03-13 2001-03-13
US29998701P 2001-06-21 2001-06-21

Publications (1)

Publication Number Publication Date
TR200602095T2 true TR200602095T2 (tr) 2007-02-21

Family

ID=27399340

Family Applications (2)

Application Number Title Priority Date Filing Date
TR2003/00478T TR200300478T2 (tr) 2000-10-13 2001-10-12 Hümanize antiLT-ß-R antikorları
TR2006/02095T TR200602095T2 (tr) 2000-10-13 2001-10-12 Hümanize Anti-LT-Beta-R antikorları

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR2003/00478T TR200300478T2 (tr) 2000-10-13 2001-10-12 Hümanize antiLT-ß-R antikorları

Country Status (25)

Country Link
US (2) US7429644B2 (tr)
EP (1) EP1326897A2 (tr)
JP (1) JP2004532608A (tr)
KR (1) KR20030041164A (tr)
CN (1) CN1547590A (tr)
AR (1) AR035352A1 (tr)
AU (2) AU1174702A (tr)
BG (1) BG107802A (tr)
BR (1) BR0114646A (tr)
CA (1) CA2425809A1 (tr)
CZ (1) CZ20031307A3 (tr)
EA (1) EA006945B1 (tr)
EE (1) EE200300179A (tr)
GE (1) GEP20063752B (tr)
HU (1) HUP0302573A2 (tr)
IL (1) IL155340A0 (tr)
IS (1) IS6779A (tr)
MX (1) MXPA03003144A (tr)
NO (1) NO20031642L (tr)
NZ (1) NZ525793A (tr)
PL (1) PL366307A1 (tr)
SK (1) SK5672003A3 (tr)
TR (2) TR200300478T2 (tr)
WO (1) WO2002030986A2 (tr)
YU (1) YU28503A (tr)

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EP2067041A2 (en) 2006-10-03 2009-06-10 Biogen Idec MA, Inc. Biomarkers and assays for the treatment of cancer
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US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
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CN106084055A (zh) 2006-11-02 2016-11-09 健泰科生物技术公司 人源化的抗‑d因子抗体
US8003761B2 (en) * 2007-01-23 2011-08-23 Hoffmann-La Roche Inc. Cancerous disease modifying antibodies
CL2008001071A1 (es) * 2007-04-17 2009-05-22 Smithkline Beecham Corp Metodo para obtener anticuerpo penta-especifico contra il-8/cxcl8, gro-alfa/cxcl1, gro-beta/cxcl2), gro-gama/cxcl3 y ena-78/cxcl5 humanas; anticuerpo penta-especifico; proceso de produccion del mismo; vector, hbridoma o celela que lo comprende; composicion farmceutica; uso para tratar copd, otras enfermedades.
NZ581468A (en) 2007-06-25 2012-09-28 Esbatech Alcon Biomed Res Unit Methods of modifying antibodies, and modified antibodies with improved functional properties
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
TWI513465B (zh) 2009-06-25 2015-12-21 Regeneron Pharma 以ｄｌｌ４拮抗劑與化學治療劑治療癌症之方法
JP6400470B2 (ja) 2011-05-16 2018-10-03 ジェネロン（シャンハイ）コーポレイション リミテッド 多重特異性Ｆａｂ融合タンパク質および使用法
WO2013012733A1 (en) 2011-07-15 2013-01-24 Biogen Idec Ma Inc. Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
MX2016001854A (es) 2013-08-12 2016-09-06 Genentech Inc Composiciones y metodo para tratar condiciones asociadas con el complemento.
SG11201608868PA (en) 2014-05-01 2016-11-29 Genentech Inc Anti-factor d antibody variants and uses thereof
PT3215528T (pt) 2014-11-06 2019-10-11 Hoffmann La Roche Variantes da região fc com ligação modificada ao fcrn e métodos de utilização
SG10201913431QA (en) 2015-07-14 2020-03-30 Immunext Inc Anti-cd154 antibody having improved binding, functional and safety characteristics and use in human immunotherapy
TW201730211A (zh) 2015-10-30 2017-09-01 建南德克公司 抗因子d抗體及結合物
JP2018536650A (ja) 2015-10-30 2018-12-13 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体変異体コンジュゲート及びその使用
WO2017157305A1 (en) 2016-03-15 2017-09-21 Generon (Shanghai) Corporation Ltd. Multispecific fab fusion proteins and use thereof
EP3847196A4 (en) 2018-09-07 2023-01-04 ITabMed (HK) Limited BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF
WO2020132810A1 (en) 2018-12-24 2020-07-02 Generon (Shanghai) Corporation Ltd. Multispecific antigen binding proteins capable of binding cd19 and cd3, and use thereof
WO2021116337A1 (en) 2019-12-11 2021-06-17 Cilag Gmbh International Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof
JP2024508207A (ja) 2020-12-02 2024-02-26 ブイアイビー ブイゼットダブリュ がんに対する組み合わせ治療におけるｌｔｂｒアゴニスト
WO2022117569A1 (en) 2020-12-02 2022-06-09 Oncurious Nv A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
CN115594759B (zh) * 2021-07-08 2026-04-24 洛阳普泰生物技术有限公司 犬轮状病毒单克隆抗体对及其应用
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WO2023218320A1 (en) * 2022-05-11 2023-11-16 Pfizer Inc. Anti-lymphotoxin beta receptor antibodies and methods of use thereof
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TW202540200A (zh) 2023-12-01 2025-10-16 美商基利科學股份有限公司 抗ｆａｐ－ｌｉｇｈｔ融合蛋白及其用途
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Also Published As

Publication number Publication date
HUP0302573A2 (hu) 2003-10-28
TR200300478T2 (tr) 2004-10-21
MXPA03003144A (es) 2004-12-06
NO20031642L (no) 2003-06-13
SK5672003A3 (en) 2003-10-07
CZ20031307A3 (cs) 2003-10-15
EA006945B1 (ru) 2006-06-30
BG107802A (bg) 2004-01-30
JP2004532608A (ja) 2004-10-28
IL155340A0 (en) 2003-11-23
BR0114646A (pt) 2006-02-21
WO2002030986A2 (en) 2002-04-18
EE200300179A (et) 2003-08-15
NO20031642D0 (no) 2003-04-10
KR20030041164A (ko) 2003-05-23
PL366307A1 (en) 2005-01-24
AU1174702A (en) 2002-04-22
NZ525793A (en) 2008-04-30
WO2002030986A3 (en) 2003-03-13
CN1547590A (zh) 2004-11-17
CA2425809A1 (en) 2002-04-18
US20040058394A1 (en) 2004-03-25
EP1326897A2 (en) 2003-07-16
US20090092601A1 (en) 2009-04-09
GEP20063752B (en) 2006-02-27
YU28503A (sh) 2006-05-25
US7429644B2 (en) 2008-09-30
EA200300464A1 (ru) 2003-10-30
AR035352A1 (es) 2004-05-12
IS6779A (is) 2003-04-11
AU2002211747B2 (en) 2007-11-29

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