TR200901984T1 - Olmesartan medoksomil ve amlodipinin katı dozaj formu - Google Patents
Olmesartan medoksomil ve amlodipinin katı dozaj formuInfo
- Publication number
- TR200901984T1 TR200901984T1 TR2009/01984T TR200901984T TR200901984T1 TR 200901984 T1 TR200901984 T1 TR 200901984T1 TR 2009/01984 T TR2009/01984 T TR 2009/01984T TR 200901984 T TR200901984 T TR 200901984T TR 200901984 T1 TR200901984 T1 TR 200901984T1
- Authority
- TR
- Turkey
- Prior art keywords
- solid dosage
- dosage form
- amlodipine
- medoxomil
- olmesartan
- Prior art date
Links
- 239000007909 solid dosage form Substances 0.000 title abstract 4
- 239000005480 Olmesartan Substances 0.000 title 1
- HTIQEAQVCYTUBX-UHFFFAOYSA-N amlodipine Chemical compound CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl HTIQEAQVCYTUBX-UHFFFAOYSA-N 0.000 title 1
- 229960000528 amlodipine Drugs 0.000 title 1
- VTRAEEWXHOVJFV-UHFFFAOYSA-N olmesartan Chemical compound CCCC1=NC(C(C)(C)O)=C(C(O)=O)N1CC1=CC=C(C=2C(=CC=CC=2)C=2NN=NN=2)C=C1 VTRAEEWXHOVJFV-UHFFFAOYSA-N 0.000 title 1
- 229960005117 olmesartan Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 abstract 1
- 229960002003 hydrochlorothiazide Drugs 0.000 abstract 1
- 229940043092 olmesartan medoxomil and amlodipine Drugs 0.000 abstract 1
- 235000000346 sugar Nutrition 0.000 abstract 1
- 150000008163 sugars Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Bu buluş, olmesartan medoksomil ve amlodipin ya da bunun farmakolojik olarak kabul edilebilen bir tuzunu içeren kararlı, katı bir dozaj formu ile ilgilidir. Özellikle de, indirgen şekerlerden muaf olan katı dozaj formları ile ilgilidir. Kararlı, katı dozaj formu isteğe bağlı olarak hidroklorotiazit ve bunun farmakolojik olarak kabul edilebilen bir tuzunu da içerebilmektedir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84509006P | 2006-09-15 | 2006-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200901984T1 true TR200901984T1 (tr) | 2009-08-21 |
Family
ID=38754721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2009/01984T TR200901984T1 (tr) | 2006-09-15 | 2007-10-12 | Olmesartan medoksomil ve amlodipinin katı dozaj formu |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20090175942A1 (tr) |
| JP (1) | JP5344620B2 (tr) |
| AT (1) | AT509493B1 (tr) |
| AU (1) | AU2007297333B2 (tr) |
| BR (1) | BRPI0716893A2 (tr) |
| CH (1) | CH703897B1 (tr) |
| DE (1) | DE212007000063U1 (tr) |
| DK (1) | DK200900369A (tr) |
| FI (1) | FI124122B (tr) |
| GB (1) | GB2454620B (tr) |
| IL (1) | IL197518A0 (tr) |
| IS (1) | IS8808A (tr) |
| MY (1) | MY157716A (tr) |
| NZ (1) | NZ575422A (tr) |
| PT (1) | PT2008032107W (tr) |
| RU (1) | RU2423975C2 (tr) |
| SE (1) | SE0900332L (tr) |
| SK (1) | SK288460B6 (tr) |
| TR (1) | TR200901984T1 (tr) |
| TW (1) | TWI399223B (tr) |
| WO (1) | WO2008032107A1 (tr) |
| ZA (1) | ZA200810616B (tr) |
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| JP2598449Y2 (ja) | 1993-08-06 | 1999-08-09 | 株式会社ソミック石川 | ボールジョイント |
| ES2510866T3 (es) | 2008-03-13 | 2014-10-21 | Daiichi Sankyo Company, Limited | Mejora de la solubilidad de una preparación que contiene olmesartán medoxomilo |
| TW201000097A (en) * | 2008-05-30 | 2010-01-01 | Daiichi Sankyo Co Ltd | Medicament for the prophylaxis or treament of hypertension |
| US20120115837A1 (en) * | 2009-04-30 | 2012-05-10 | Takeda Pharmaceutical Company Limited | Solid Preparation |
| JP5719385B2 (ja) * | 2010-02-24 | 2015-05-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ラミプリル及びベシル酸アムロジピンの固形医薬製剤及びその製造 |
| EP2425859A1 (en) * | 2010-08-08 | 2012-03-07 | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi | Olmesartan formulations |
| CN102028663B (zh) * | 2010-12-14 | 2011-11-30 | 北京万生药业有限责任公司 | 一种稳定的奥美沙坦酯固体制剂 |
| JP6018420B2 (ja) * | 2012-06-05 | 2016-11-02 | ニプロ株式会社 | アンジオテンシンii受容体拮抗薬およびサイアザイド系利尿薬を含む医薬組成物 |
| CN103565807B (zh) * | 2012-07-25 | 2015-11-04 | 天津市汉康医药生物技术有限公司 | 一种奥美沙坦酯氨氯地平药物组合物 |
| WO2014058047A1 (ja) * | 2012-10-12 | 2014-04-17 | 味の素株式会社 | カルシウム拮抗薬/アンジオテンシンii受容体拮抗薬含有医薬製剤の製造方法 |
| JP5871984B2 (ja) * | 2013-04-15 | 2016-03-01 | 株式会社三和化学研究所 | オルメサルタンメドキソミルを含有する医薬組成物 |
| JPWO2014188729A1 (ja) * | 2013-05-24 | 2017-02-23 | 持田製薬株式会社 | 経口用組成物 |
| EP2883539A1 (en) | 2013-12-12 | 2015-06-17 | Sanovel Ilac Sanayi ve Ticaret A.S. | Pharmaceutical combinations of olmesartan and amlodipine |
| CN104739799B (zh) * | 2013-12-27 | 2018-01-05 | 辰欣药业股份有限公司 | 一种用于直接压片的苯磺酸氨氯地平组合物及其片剂制备方法 |
| KR102222917B1 (ko) * | 2014-06-25 | 2021-03-05 | 한림제약(주) | 암로디핀 및 올메사탄 메독소밀을 포함하는 약학 조성물 |
| CN104997778A (zh) * | 2015-07-08 | 2015-10-28 | 南京正大天晴制药有限公司 | 一种奥美沙坦酯氨氯地平药物组合物 |
| CN105902510A (zh) * | 2015-12-24 | 2016-08-31 | 嘉实(湖南)医药科技有限公司 | 一种奥美沙坦酯氨氯地平复方制剂的制备工艺 |
| AU2020229265B2 (en) * | 2019-02-26 | 2023-09-14 | Daewoong Pharmaceutical Co., Ltd. | Pharmaceutical composition of single dosage form for treating or preventing hypertension and hyperlipidemia |
| CN115300476B (zh) * | 2022-09-01 | 2024-04-16 | 华润双鹤药业股份有限公司 | 一种药物组合物及其制备方法 |
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-
2007
- 2007-09-14 TW TW096134347A patent/TWI399223B/zh active
- 2007-10-12 PT PT2007003933A patent/PT2008032107W/pt unknown
- 2007-10-12 JP JP2009527899A patent/JP5344620B2/ja active Active
- 2007-10-12 AU AU2007297333A patent/AU2007297333B2/en active Active
- 2007-10-12 GB GB0903844A patent/GB2454620B/en active Active
- 2007-10-12 WO PCT/GB2007/003933 patent/WO2008032107A1/en not_active Ceased
- 2007-10-12 SE SE0900332A patent/SE0900332L/sv unknown
- 2007-10-12 RU RU2009114166/15A patent/RU2423975C2/ru active
- 2007-10-12 DE DE212007000063U patent/DE212007000063U1/de not_active Ceased
- 2007-10-12 SK SK5021-2009A patent/SK288460B6/sk unknown
- 2007-10-12 CH CH00742/08A patent/CH703897B1/de unknown
- 2007-10-12 NZ NZ575422A patent/NZ575422A/en unknown
- 2007-10-12 BR BRPI0716893-4A2A patent/BRPI0716893A2/pt not_active Application Discontinuation
- 2007-10-12 TR TR2009/01984T patent/TR200901984T1/tr unknown
- 2007-10-12 MY MYPI20091051A patent/MY157716A/en unknown
- 2007-10-12 AT AT0939307A patent/AT509493B1/de active
-
2008
- 2008-12-15 ZA ZA200810616A patent/ZA200810616B/xx unknown
-
2009
- 2009-03-10 IL IL197518A patent/IL197518A0/en unknown
- 2009-03-11 US US12/401,748 patent/US20090175942A1/en not_active Abandoned
- 2009-03-12 IS IS8808A patent/IS8808A/is unknown
- 2009-03-13 FI FI20090094A patent/FI124122B/fi active IP Right Grant
- 2009-03-16 DK DK200900369A patent/DK200900369A/en not_active Application Discontinuation
-
2015
- 2015-06-09 US US14/734,893 patent/US20160129008A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2009114166A (ru) | 2010-10-20 |
| WO2008032107A1 (en) | 2008-03-20 |
| GB2454620A (en) | 2009-05-13 |
| TWI399223B (zh) | 2013-06-21 |
| US20160129008A1 (en) | 2016-05-12 |
| NZ575422A (en) | 2011-01-28 |
| GB2454620B (en) | 2011-08-17 |
| FI124122B (fi) | 2014-03-31 |
| FI20090094L (fi) | 2009-03-13 |
| TW200817052A (en) | 2008-04-16 |
| SE0900332L (sv) | 2009-06-12 |
| HK1127282A1 (en) | 2009-09-25 |
| AT509493A5 (de) | 2011-09-15 |
| ZA200810616B (en) | 2009-08-26 |
| MY157716A (en) | 2016-07-15 |
| AU2007297333A1 (en) | 2008-03-20 |
| SK50212009A3 (sk) | 2009-06-05 |
| AT509493B1 (de) | 2012-01-15 |
| GB0903844D0 (en) | 2009-04-22 |
| RU2423975C2 (ru) | 2011-07-20 |
| BRPI0716893A2 (pt) | 2014-05-06 |
| IS8808A (is) | 2009-03-12 |
| IL197518A0 (en) | 2009-12-24 |
| SK288460B6 (sk) | 2017-03-01 |
| DE212007000063U1 (de) | 2009-05-14 |
| JP5344620B2 (ja) | 2013-11-20 |
| US20090175942A1 (en) | 2009-07-09 |
| JP2011500505A (ja) | 2011-01-06 |
| DK200900369A (en) | 2009-03-16 |
| CH703897B1 (de) | 2012-04-13 |
| PT2008032107W (pt) | 2013-07-09 |
| AU2007297333B2 (en) | 2010-10-28 |
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