TR201907493T4 - RNA interferansının azaltılması aracılığıyla ökaryotik hücrelerde bir transgenin ekspresyonunun arttırılması. - Google Patents

RNA interferansının azaltılması aracılığıyla ökaryotik hücrelerde bir transgenin ekspresyonunun arttırılması. Download PDF

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Publication number
TR201907493T4
TR201907493T4 TR2019/07493T TR201907493T TR201907493T4 TR 201907493 T4 TR201907493 T4 TR 201907493T4 TR 2019/07493 T TR2019/07493 T TR 2019/07493T TR 201907493 T TR201907493 T TR 201907493T TR 201907493 T4 TR201907493 T4 TR 201907493T4
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Turkey
Prior art keywords
transgene
eukaryotic cells
expression
reduction
increasing
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TR2019/07493T
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English (en)
Inventor
Miasnikov Andrei
Original Assignee
Danisco Inc
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Application filed by Danisco Inc filed Critical Danisco Inc
Publication of TR201907493T4 publication Critical patent/TR201907493T4/tr

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    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
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    • C12N9/2414—Alpha-amylase (3.2.1.1.)
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    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
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    • C12Y207/07—Nucleotidyltransferases (2.7.7)
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    • C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003—Ribonuclease III (3.1.26.3)
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01091—Cellulose 1,4-beta-cellobiosidase (3.2.1.91)
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    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)

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Abstract

RNA interferansının (RNAi) azaltılması aracılığıyla ökaryotik hücrelerde bir transgenin ekspresyonunun arttırılmasına yönelik yöntemler ve yöntem tarafından üretilen değişken hücreler açıklanmaktadır. Yöntemler ve değişken hücreler, örneğin ökaryotik hücrelerde terapötik ve endüstriyel polipeptitlerin verimli üretimine yönelik faydalıdır.
TR2019/07493T 2013-08-08 2014-07-31 RNA interferansının azaltılması aracılığıyla ökaryotik hücrelerde bir transgenin ekspresyonunun arttırılması. TR201907493T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361863829P 2013-08-08 2013-08-08

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TR201907493T4 true TR201907493T4 (tr) 2019-06-21

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TR2019/07493T TR201907493T4 (tr) 2013-08-08 2014-07-31 RNA interferansının azaltılması aracılığıyla ökaryotik hücrelerde bir transgenin ekspresyonunun arttırılması.

Country Status (12)

Country Link
US (1) US10450575B2 (tr)
EP (1) EP3030661B1 (tr)
CN (1) CN105683380B (tr)
CA (1) CA2920564C (tr)
DK (1) DK3030661T3 (tr)
ES (1) ES2727530T3 (tr)
LT (1) LT3030661T (tr)
PL (1) PL3030661T3 (tr)
PT (1) PT3030661T (tr)
SI (1) SI3030661T1 (tr)
TR (1) TR201907493T4 (tr)
WO (1) WO2015020876A1 (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015168733A1 (en) * 2014-05-05 2015-11-12 Queensland University Of Technology Decoy molecules
US20240376512A1 (en) 2021-09-09 2024-11-14 Dupont Nutrition Biosciences Aps Over expression of foldases and chaperones improves protein production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1302885B1 (it) * 1998-11-30 2000-10-10 Univ Roma Isolamento e caratterizzazione di un gene per il silenziamento genicoda n. crassa e suoi usi.
IT1306014B1 (it) * 1999-02-22 2001-05-23 Univ Roma Isolamento e caratterizzazione di un gene per il silenziamento genicoda n. crassa e suoi usi.
EP1235842A4 (en) * 1999-10-15 2003-04-23 Univ Massachusetts Rna interference pathway genes as tools for targeted genetic interference
GB201012845D0 (en) * 2010-07-30 2010-09-15 Vib Vzw Inhibition of dicer function for treatment of cancer
WO2012036810A2 (en) * 2010-09-15 2012-03-22 The Regents Of The University Of California Thermophilic mutants of trichoderma reesei endoglucanase i
RU2013122800A (ru) 2010-10-20 2014-11-27 ДАНИСКО ЮЭс ИНК. Термостабильная целлюлаза из trichoderma

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Publication number Publication date
CN105683380B (zh) 2020-07-03
CA2920564A1 (en) 2015-02-12
CA2920564C (en) 2021-11-09
LT3030661T (lt) 2019-04-25
WO2015020876A1 (en) 2015-02-12
DK3030661T3 (da) 2019-06-11
EP3030661B1 (en) 2019-02-27
SI3030661T1 (sl) 2019-06-28
US10450575B2 (en) 2019-10-22
CN105683380A (zh) 2016-06-15
EP3030661A1 (en) 2016-06-15
PT3030661T (pt) 2019-06-06
PL3030661T3 (pl) 2019-06-28
ES2727530T3 (es) 2019-10-16
US20160177319A1 (en) 2016-06-23

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