TW200510540A - Crystal structure - Google Patents

Crystal structure

Info

Publication number
TW200510540A
TW200510540A TW093112336A TW93112336A TW200510540A TW 200510540 A TW200510540 A TW 200510540A TW 093112336 A TW093112336 A TW 093112336A TW 93112336 A TW93112336 A TW 93112336A TW 200510540 A TW200510540 A TW 200510540A
Authority
TW
Taiwan
Prior art keywords
pde5
ligands
crystals
present
relates
Prior art date
Application number
TW093112336A
Other languages
English (en)
Chinese (zh)
Inventor
David Graham Brown
Colin Roger Groom
Andrew Lee Hopkins
Timothy Mark Jenkins
Sarah Helen Kamp
Gara Margaret Mary O'
Heather Joan Ringrose
Colin Mark Robinson
Wendy Elaine Taylor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of TW200510540A publication Critical patent/TW200510540A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
TW093112336A 2003-05-01 2004-04-30 Crystal structure TW200510540A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0310058 2003-05-01

Publications (1)

Publication Number Publication Date
TW200510540A true TW200510540A (en) 2005-03-16

Family

ID=33397043

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093112336A TW200510540A (en) 2003-05-01 2004-04-30 Crystal structure

Country Status (10)

Country Link
EP (1) EP1623026A1 (pt)
JP (1) JP2006525801A (pt)
AR (1) AR044133A1 (pt)
BR (1) BRPI0409931A (pt)
CA (1) CA2522472A1 (pt)
CL (1) CL2004000926A1 (pt)
MX (1) MXPA05011769A (pt)
RU (1) RU2005133628A (pt)
TW (1) TW200510540A (pt)
WO (1) WO2004097010A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2152876A2 (en) * 2007-05-02 2010-02-17 Sirna Therapeutics Inc. Rna interference mediated inhibition of cyclic nucleotide type 4 phosphodiesterase (pde4b) gene expression using short interfering nucleic acid (sina)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE199569T1 (de) * 1993-05-27 2001-03-15 Univ Washington Cyclisch gmp bindende cyclisch gmp spezifische phosphodiesterase materialien und verfahren.
GB9923968D0 (en) * 1999-10-11 1999-12-15 Pfizer Ltd Therapeutic agents
GB0126417D0 (en) * 2001-11-02 2002-01-02 Pfizer Ltd Crystal structure

Also Published As

Publication number Publication date
WO2004097010A1 (en) 2004-11-11
CA2522472A1 (en) 2004-11-11
BRPI0409931A (pt) 2006-04-25
EP1623026A1 (en) 2006-02-08
JP2006525801A (ja) 2006-11-16
RU2005133628A (ru) 2007-05-10
MXPA05011769A (es) 2006-01-26
CL2004000926A1 (es) 2005-04-22
AR044133A1 (es) 2005-08-24

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