AR044133A1 - Estructura cristalina de la fosfodiesterasa 5 - Google Patents

Estructura cristalina de la fosfodiesterasa 5

Info

Publication number
AR044133A1
AR044133A1 ARP040101466A ARP040101466A AR044133A1 AR 044133 A1 AR044133 A1 AR 044133A1 AR P040101466 A ARP040101466 A AR P040101466A AR P040101466 A ARP040101466 A AR P040101466A AR 044133 A1 AR044133 A1 AR 044133A1
Authority
AR
Argentina
Prior art keywords
pde5
compound
protein
dimensional representation
ligands
Prior art date
Application number
ARP040101466A
Other languages
English (en)
Spanish (es)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of AR044133A1 publication Critical patent/AR044133A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
ARP040101466A 2003-05-01 2004-04-29 Estructura cristalina de la fosfodiesterasa 5 AR044133A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0310058 2003-05-01

Publications (1)

Publication Number Publication Date
AR044133A1 true AR044133A1 (es) 2005-08-24

Family

ID=33397043

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040101466A AR044133A1 (es) 2003-05-01 2004-04-29 Estructura cristalina de la fosfodiesterasa 5

Country Status (10)

Country Link
EP (1) EP1623026A1 (pt)
JP (1) JP2006525801A (pt)
AR (1) AR044133A1 (pt)
BR (1) BRPI0409931A (pt)
CA (1) CA2522472A1 (pt)
CL (1) CL2004000926A1 (pt)
MX (1) MXPA05011769A (pt)
RU (1) RU2005133628A (pt)
TW (1) TW200510540A (pt)
WO (1) WO2004097010A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2152876A2 (en) * 2007-05-02 2010-02-17 Sirna Therapeutics Inc. Rna interference mediated inhibition of cyclic nucleotide type 4 phosphodiesterase (pde4b) gene expression using short interfering nucleic acid (sina)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE199569T1 (de) * 1993-05-27 2001-03-15 Univ Washington Cyclisch gmp bindende cyclisch gmp spezifische phosphodiesterase materialien und verfahren.
GB9923968D0 (en) * 1999-10-11 1999-12-15 Pfizer Ltd Therapeutic agents
GB0126417D0 (en) * 2001-11-02 2002-01-02 Pfizer Ltd Crystal structure

Also Published As

Publication number Publication date
WO2004097010A1 (en) 2004-11-11
CA2522472A1 (en) 2004-11-11
BRPI0409931A (pt) 2006-04-25
EP1623026A1 (en) 2006-02-08
TW200510540A (en) 2005-03-16
JP2006525801A (ja) 2006-11-16
RU2005133628A (ru) 2007-05-10
MXPA05011769A (es) 2006-01-26
CL2004000926A1 (es) 2005-04-22

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