TW201910314A - 新穎化合物 - Google Patents

新穎化合物 Download PDF

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Publication number
TW201910314A
TW201910314A TW107128474A TW107128474A TW201910314A TW 201910314 A TW201910314 A TW 201910314A TW 107128474 A TW107128474 A TW 107128474A TW 107128474 A TW107128474 A TW 107128474A TW 201910314 A TW201910314 A TW 201910314A
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Taiwan
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group
substituted
mmol
disease
compound
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TW107128474A
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English (en)
Chinese (zh)
Inventor
馬修 庫博
大衛 米勒
安格斯 麥克羅德
吉米 凡威爾頓伯格
史蒂芬 索馬
史蒂芬 聖加雷
強納森 夏農
湯瑪斯 阿拉奈恩
史都華 歐尼恩斯
伊恩 史特拉特
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愛爾蘭商英弗雷佐姆有限公司
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Priority claimed from GBGB1713082.4A external-priority patent/GB201713082D0/en
Priority claimed from GBGB1718563.8A external-priority patent/GB201718563D0/en
Priority claimed from GBGB1721726.6A external-priority patent/GB201721726D0/en
Priority claimed from GBGB1810983.5A external-priority patent/GB201810983D0/en
Application filed by 愛爾蘭商英弗雷佐姆有限公司 filed Critical 愛爾蘭商英弗雷佐姆有限公司
Publication of TW201910314A publication Critical patent/TW201910314A/zh

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

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CN111132974B (zh) 2023-11-21
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KR20200041918A (ko) 2020-04-22
CA3071143A1 (fr) 2019-02-21
MA49901A (fr) 2020-06-24
UY37845A (es) 2020-06-30
US20200361895A1 (en) 2020-11-19
WO2019034686A1 (fr) 2019-02-21
AU2018317794A1 (en) 2020-02-13
JP2023055855A (ja) 2023-04-18
EP3668861A1 (fr) 2020-06-24
RU2020110366A3 (fr) 2022-02-21
SG11202001164SA (en) 2020-03-30
BR112020002948A2 (pt) 2020-08-11
CN111132974A (zh) 2020-05-08
IL272555A (en) 2020-03-31

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