UA109105C2 - Молекула нуклеїнової кислоти, що кодує істотно нетоксичний мутеїн альфа-токсину clostridium perfringens, та істотно нетоксичний мутеїн альфа-токсину clostridium perfringens - Google Patents

Молекула нуклеїнової кислоти, що кодує істотно нетоксичний мутеїн альфа-токсину clostridium perfringens, та істотно нетоксичний мутеїн альфа-токсину clostridium perfringens

Info

Publication number: UA109105C2
Authority: UA; Ukraine
Prior art keywords: toxin; nucleic acid; musheline; clstine; trophy
Prior art date: 2006-04-17

Application number

UAA201106572A

Other languages

English (en)

Ukrainian (uk)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-17

Filing date

2007-04-12

Publication date

2015-07-27

2007-04-12 Application filed filed Critical

2015-07-27 Publication of UA109105C2 publication Critical patent/UA109105C2/ru

Links

231100000252 nontoxic Toxicity 0.000 title abstract 3
230000003000 nontoxic effect Effects 0.000 title abstract 3
241000193468 Clostridium perfringens Species 0.000 title abstract 2
150000007523 nucleic acids Chemical class 0.000 title abstract 2
102000039446 nucleic acids Human genes 0.000 title abstract 2
108020004707 nucleic acids Proteins 0.000 title abstract 2
NMNIAXSDJGZKKT-UHFFFAOYSA-N methyl 3-hydroxy-4-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]pentanoate Chemical compound C1=CC(OC(C)C(O)CC(=O)OC)=CC=C1OC1=CC=C(C(F)(F)F)C=N1 NMNIAXSDJGZKKT-UHFFFAOYSA-N 0.000 title 1
239000003053 toxin Substances 0.000 title 1
125000000539 amino acid group Chemical group 0.000 abstract 3
101710092462 Alpha-hemolysin Proteins 0.000 abstract 2
101710197219 Alpha-toxin Proteins 0.000 abstract 2
101710124951 Phospholipase C Proteins 0.000 abstract 2
239000002776 alpha toxin Substances 0.000 abstract 2
125000003275 alpha amino acid group Chemical group 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Mycology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Communicable Diseases (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Fodder In General (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Feed For Specific Animals (AREA)

UAA201106572A 2006-04-17 2007-04-12 Молекула нуклеїнової кислоти, що кодує істотно нетоксичний мутеїн альфа-токсину clostridium perfringens, та істотно нетоксичний мутеїн альфа-токсину clostridium perfringens UA109105C2 (uk)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US79255306P	2006-04-17	2006-04-17

Publications (1)

Publication Number	Publication Date
UA109105C2 true UA109105C2 (uk)	2015-07-27

Family

ID=38625523

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
UAA201106572A UA109105C2 (uk)	2006-04-17	2007-04-12	Молекула нуклеїнової кислоти, що кодує істотно нетоксичний мутеїн альфа-токсину clostridium perfringens, та істотно нетоксичний мутеїн альфа-токсину clostridium perfringens
UAA200813301A UA95951C2 (en)	2006-04-17	2007-12-04	Recombinant attenuated clostridium organisms

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
UAA200813301A UA95951C2 (en)	2006-04-17	2007-12-04	Recombinant attenuated clostridium organisms

Country Status (23)

Country	Link
US (3)	US7732187B2 (ru)
EP (2)	EP2368571A1 (ru)
JP (2)	JP5551933B2 (ru)
KR (1)	KR20080110908A (ru)
CN (1)	CN101489584B (ru)
AR (2)	AR060471A1 (ru)
AU (1)	AU2007240949B2 (ru)
BR (1)	BRPI0711572A2 (ru)
CA (1)	CA2649426C (ru)
CO (1)	CO6140037A2 (ru)
EC (1)	ECSP088827A (ru)
ES (1)	ES2401810T3 (ru)
IL (1)	IL194714A (ru)
MX (1)	MX2008013451A (ru)
NO (1)	NO20084810L (ru)
NZ (1)	NZ571970A (ru)
PE (1)	PE20080167A1 (ru)
PL (1)	PL2007420T3 (ru)
RU (2)	RU2445364C2 (ru)
TW (1)	TWI338045B (ru)
UA (2)	UA109105C2 (ru)
WO (1)	WO2007123850A2 (ru)
ZA (1)	ZA200808872B (ru)

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US20070077256A1 (en)	1999-11-19	2007-04-05	Los Angeles Biomedical Research Institute	Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents
US20060083750A1 (en) *	1999-11-19	2006-04-20	Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center	Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis
JP2011519049A (ja) *	2008-04-29	2011-06-30	イミューンエクサイトインコーポレイテッド	免疫調節組成物およびその使用方法
EP2613802A4 (en) *	2010-09-10	2014-03-26	Viropharma Inc	ENVIRONMENTAL CLOSTRIDAL BACTERIOTHERAPY AND ASSOCIATED FORMULATIONS AND METHODS OF MAKING AND USING SAME
GEP201706766B (en)	2011-07-22	2017-10-25	Los Angeles Biomedical Res Center	Methods and compositions for vaccinating against staphylococcus aureus
AR090219A1 (es) *	2012-03-02	2014-10-29	Regeneron Pharma	Anticuerpos humanos frente a toxinas de clostridium difficile
ES2759583T3 (es)	2012-10-26	2020-05-11	Intervet Int Bv	Vacunas de Salmonella de protección cruzada
US10130691B2 (en)	2013-03-15	2018-11-20	Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center	Compositions and methods for treating fungal and bacterial pathogens
EP3426287A4 (en)	2016-03-09	2020-03-11	Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center	Methods and kits for use in preventing and treating vulvovaginal candidiasis
CN109602898B (zh) *	2018-12-28	2022-02-22	江苏省农业科学院	一种产气荚膜梭菌α毒素基因工程疫苗及其制备方法
US10973908B1 (en)	2020-05-14	2021-04-13	David Gordon Bermudes	Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en)	2020-07-22	2026-01-27	David Gordon Bermudes	Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
GB202019767D0 (en)	2020-12-15	2021-01-27	Chain Biotechnology Ltd	Compostitions and methods
CN114621963A (zh) *	2022-03-11	2022-06-14	牧原食品股份有限公司	一种猪魏氏梭菌a型的亚单位疫苗及其制备
CN116970505A (zh) *	2022-04-22	2023-10-31	金宇保灵生物药品有限公司	一种A型产气荚膜梭菌α毒素的产毒培养基及其制备方法和应用

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GB1483042A (en) *	1974-07-29	1977-08-17	Lapointe J	Anti-tumour product of bacterial origin
SU627611A1 (ru)	1977-09-30	1980-02-05	В.П. Землякова	Вакцинный препарат в.п. земл ковой против клостридиозов животных и птиц
GB9115332D0 (en) *	1991-07-16	1991-08-28	Connaught Lab	Manipulation of gene copy number in bordetella
NZ253189A (en) *	1992-05-20	1996-08-27	Secr Defence	Peptides comprising amino acid sequences of clostridium perfringens alpha toxins, vaccines containing them, antibodies and their use
GB9605222D0 (en)	1996-03-12	1996-05-15	Secr Defence	Clostridium perfringens epsilon toxin vaccines
ES2276448T3 (es) *	1997-06-20	2007-06-16	Intervet International Bv	Vacuna contra clostridium perfringens.
RU2129441C1 (ru) *	1997-12-10	1999-04-27	Пирожков Михаил Константинович	Вакцина, ассоциированная против анаэробной энтеротоксемии и эшерихиоза поросят
US6399074B1 (en) *	1998-07-24	2002-06-04	Megan Health, Inc.	Live attenuated salmonella vaccines to control avian pathogens
AUPQ899700A0 (en) *	2000-07-25	2000-08-17	Borody, Thomas Julius	Probiotic recolonisation therapy
US6908620B2 (en) *	2002-12-09	2005-06-21	University Of Georgia Research Foundation, Inc.	Coccidial vaccine and methods of making and using same
JP2007512006A (ja) *	2003-11-10	2007-05-17	ザユーエービーリサーチファウンデーション	細菌輸送およびｃｎｓ侵襲を低減させるための組成物およびこの組成物を使用する方法
MY149604A (en)	2005-04-18	2013-09-13	Schering Plough Ltd	C.perfringens alpha toxoid vaccine

2007
- 2007-04-12 BR BRPI0711572-5A patent/BRPI0711572A2/pt not_active IP Right Cessation
- 2007-04-12 UA UAA201106572A patent/UA109105C2/ru unknown
- 2007-04-12 ES ES07755417T patent/ES2401810T3/es active Active
- 2007-04-12 CN CN2007800225963A patent/CN101489584B/zh not_active Expired - Fee Related
- 2007-04-12 WO PCT/US2007/009135 patent/WO2007123850A2/en not_active Ceased
- 2007-04-12 MX MX2008013451A patent/MX2008013451A/es active IP Right Grant
- 2007-04-12 KR KR1020087027923A patent/KR20080110908A/ko not_active Ceased
- 2007-04-12 JP JP2009506518A patent/JP5551933B2/ja not_active Expired - Fee Related
- 2007-04-12 AU AU2007240949A patent/AU2007240949B2/en not_active Ceased
- 2007-04-12 CA CA2649426A patent/CA2649426C/en not_active Expired - Fee Related
- 2007-04-12 RU RU2008144913/10A patent/RU2445364C2/ru active
- 2007-04-12 RU RU2011147308/10A patent/RU2593945C2/ru active
- 2007-04-12 US US11/734,454 patent/US7732187B2/en active Active
- 2007-04-12 PL PL07755417T patent/PL2007420T3/pl unknown
- 2007-04-12 EP EP11157448A patent/EP2368571A1/en not_active Withdrawn
- 2007-04-12 NZ NZ571970A patent/NZ571970A/en not_active IP Right Cessation
- 2007-04-12 EP EP07755417A patent/EP2007420B1/en active Active
- 2007-04-16 AR ARP070101608A patent/AR060471A1/es active IP Right Grant
- 2007-04-16 PE PE2007000464A patent/PE20080167A1/es not_active Application Discontinuation
- 2007-04-17 TW TW096113489A patent/TWI338045B/zh not_active IP Right Cessation
- 2007-12-04 UA UAA200813301A patent/UA95951C2/ru unknown
2008
- 2008-10-12 IL IL194714A patent/IL194714A/en not_active IP Right Cessation
- 2008-10-16 EC EC2008008827A patent/ECSP088827A/es unknown
- 2008-10-16 ZA ZA200808872A patent/ZA200808872B/xx unknown
- 2008-10-17 CO CO08110815A patent/CO6140037A2/es unknown
- 2008-11-14 NO NO20084810A patent/NO20084810L/no not_active Application Discontinuation
2009
- 2009-12-17 US US12/640,645 patent/US7807456B2/en active Active
2010
- 2010-08-27 US US12/869,813 patent/US7972604B2/en active Active
2011
- 2011-01-19 AR ARP110100176A patent/AR079941A2/es not_active Application Discontinuation
2013
- 2013-09-17 JP JP2013191854A patent/JP2013255518A/ja active Pending

Also Published As

Publication number	Publication date
RU2593945C2 (ru)	2016-08-10
WO2007123850A2 (en)	2007-11-01
RU2445364C2 (ru)	2012-03-20
US7972604B2 (en)	2011-07-05
PE20080167A1 (es)	2008-03-10
RU2008144913A (ru)	2010-05-27
IL194714A0 (en)	2011-08-01
IL194714A (en)	2015-03-31
JP2013255518A (ja)	2013-12-26
CN101489584B (zh)	2013-05-01
ES2401810T3 (es)	2013-04-24
NO20084810L (no)	2009-01-16
NZ571970A (en)	2012-02-24
AR060471A1 (es)	2008-06-18
MX2008013451A (es)	2008-10-30
AU2007240949A1 (en)	2007-11-01
US20110008389A1 (en)	2011-01-13
TWI338045B (en)	2011-03-01
EP2007420B1 (en)	2013-03-06
KR20080110908A (ko)	2008-12-19
EP2368571A1 (en)	2011-09-28
US20100166800A1 (en)	2010-07-01
RU2011147308A (ru)	2013-05-27
BRPI0711572A2 (pt)	2011-11-16
JP2009533071A (ja)	2009-09-17
AR079941A2 (es)	2012-02-29
ZA200808872B (en)	2009-11-25
CA2649426A1 (en)	2007-11-01
US20070286874A1 (en)	2007-12-13
CN101489584A (zh)	2009-07-22
UA95951C2 (en)	2011-09-26
JP5551933B2 (ja)	2014-07-16
PL2007420T3 (pl)	2013-08-30
EP2007420A2 (en)	2008-12-31
AU2007240949B2 (en)	2013-03-14
HK1125315A1 (en)	2009-08-07
TW200801182A (en)	2008-01-01
WO2007123850A3 (en)	2008-03-06
CO6140037A2 (es)	2010-03-19
ECSP088827A (es)	2008-11-27
CA2649426C (en)	2014-04-01
US7732187B2 (en)	2010-06-08
US7807456B2 (en)	2010-10-05

Publication	Publication Date	Title
UA109105C2 (uk)	2015-07-27	Молекула нуклеїнової кислоти, що кодує істотно нетоксичний мутеїн альфа-токсину clostridium perfringens, та істотно нетоксичний мутеїн альфа-токсину clostridium perfringens
ATE417595T1 (de)	2009-01-15	Keratin-bindende polypeptide
HRP20090245T1 (en)	2009-07-31	Pyy agonists and uses thereof
MX347545B (es)	2017-05-02	Polipeptidos con actividad xilanasa.
NZ600732A (en)	2014-06-27	Oxyntomodulin peptide analogue
DE60330346D1 (de)	2010-01-14	Mehrfachsubstituierte proteasevarianten
NZ583783A (en)	2012-10-26	Avian interferon-lambda polypeptide and genetic sequences encoding the same
WO2009069808A1 (ja)	2009-06-04	新規活性を有するEphA4ポリペプチドおよびその用途
ATE551048T1 (de)	2012-04-15	Proteinhydrolysate enthaltende kosmetische zusammensetzungen
DE602006018856D1 (de)	2011-01-27	Neue nutrazeutika-zusammensetzungen
CY1111630T1 (el)	2015-10-07	Παραγωγα κυτοκινων
ATE548380T1 (de)	2012-03-15	Mutante des hgf-precursor-proteins und aktivierte form davon
WO2006134190A8 (es)	2008-01-31	Agentes y métodos basados en el uso del dominio eda de la fibronectina
NZ601647A (en)	2013-09-27	Variant hhip1 protein and methods and uses thereof
DE602004028266D1 (de)	2010-09-02	Angiogene peptide und ihre verwendungen
MX2007000334A (es)	2007-06-25	Polipeptido.
DK1664102T3 (da)	2012-02-27	Isoleret photoprotein mtclytin, samt dets anvendelse
DE50013400D1 (de)	2006-10-12	Dna-sequenz und rekombinante herstellung eines graminaen-allergens
DK1174469T3 (da)	2006-09-18	Lineære polydialkylorganosiloxaner med polyoxyalkylen- og aminofunktionelle grupper, som yderligere har endestillede alkoxygrupper
WO2006097432A3 (de)	2007-04-19	Keratin-biktdende desmoplakinpolypeptidsequenzen
WO2007058267A8 (ja)	2008-02-14	新規タンパク質及びそれをコードする遺伝子
NO20081503L (no)	2008-06-30	T-celle adhesjonsmolekyl, og antistoff dertil
SE0101519D0 (sv)	2001-04-27	Nucleic ACID
WO2005057486A3 (en)	2005-08-11	Protein engineering with analogous contact environments
DE602005016417D1 (de)	2009-10-15	Neue polypeptide zur in-vintro-isolierung und vorbeugung von infektionen mit legionella pneumophila